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RU2011150214A - Bifidobacterium longum NCC2705 (CNCM 1-2618) И ИММУННЫЕ РАССТРОЙСТВА - Google Patents

Bifidobacterium longum NCC2705 (CNCM 1-2618) И ИММУННЫЕ РАССТРОЙСТВА Download PDF

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Publication number
RU2011150214A
RU2011150214A RU2011150214/02A RU2011150214A RU2011150214A RU 2011150214 A RU2011150214 A RU 2011150214A RU 2011150214/02 A RU2011150214/02 A RU 2011150214/02A RU 2011150214 A RU2011150214 A RU 2011150214A RU 2011150214 A RU2011150214 A RU 2011150214A
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RU
Russia
Prior art keywords
cncm
composition according
longum ncc
replicating
infections
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RU2011150214/02A
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English (en)
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RU2554772C2 (ru
Inventor
Валери ПТИ
Клара ГАРСИЯ-РОДЕНАС
Моник ЮЛИТА
Гюноле ПРИУ
Анник МЕРСЕНЬЕ
Софи НЮТТЕН
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Нестек С.А.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42646295&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2011150214(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP09159925A external-priority patent/EP2251020A1/en
Priority claimed from EP09159929A external-priority patent/EP2251022A1/en
Application filed by Нестек С.А. filed Critical Нестек С.А.
Publication of RU2011150214A publication Critical patent/RU2011150214A/ru
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Abstract

1. Композиция, содержащая B.longum NCC 2705, депозитарный номер CNCM 1-2618, для применения при лечении или при профилактике инфекций и расстройств, связанных с иммунной системой, включая инфекции.2. Композиция по п.1, в которой B.longum NCC 2705 CNCM 1-2618 приведен, по меньшей мере, частично в нереплицирующееся состояние термической инактивацией, предпочтительно обработкой, по меньшей мере, при около 70°C.3. Композиция по п.2, в которой термическую обработку проводят в течение, по меньшей мере, 10 с.4. Композиция по п.1, в которой B.longum NCC 2705 CNCM I-2618 приведен в нереплицирующееся состояние температурой от 110°C до 140°C в течение 10-20 с или температурой от 75°C до 95°C в течение 10-30 мин.5. Композиция по п.1, которая содержит количество нереплицирующихся B.longum NCC 2705 CNCM 1-2618, соответствующее диапазону от около 10до 10КОЕ на ежедневную дозу.6. Композиция по п.1, которая содержит около 0,005-1000 мг нереплицирующихся B.longum NCC 2705 CNCM 1-2618 на ежедневную дозу.7. Композиция по п.1, в которой, по меньшей мере, 95% B.longum NCC 2705 CNCM 1-2618 являются нереплицирующимися, предпочтительно все B.longum NCC 2705 CNCM 1-2618 являются нереплицирующимися.8. Композиция по любому из предшествующих пунктов, которая выбрана из группы, состоящей из пищевых композиций, пищевых продуктов, включая пищу для домашних животных, напитков, диетических смесей, питательных смесей, нутрицевтиков, биологически активных добавок к пище, фармацевтических композиций, косметических композиций, композиций для местного применения и лекарственных средств.9. Композиция по п.1, в которой расстройство, связанное с иммунной системой, выбирают из группы, состоящей из инфекций, в частности из бактериальной, вирусной, грибковой и/или паразитарной инфе�

Claims (15)

1. Композиция, содержащая B.longum NCC 2705, депозитарный номер CNCM 1-2618, для применения при лечении или при профилактике инфекций и расстройств, связанных с иммунной системой, включая инфекции.
2. Композиция по п.1, в которой B.longum NCC 2705 CNCM 1-2618 приведен, по меньшей мере, частично в нереплицирующееся состояние термической инактивацией, предпочтительно обработкой, по меньшей мере, при около 70°C.
3. Композиция по п.2, в которой термическую обработку проводят в течение, по меньшей мере, 10 с.
4. Композиция по п.1, в которой B.longum NCC 2705 CNCM I-2618 приведен в нереплицирующееся состояние температурой от 110°C до 140°C в течение 10-20 с или температурой от 75°C до 95°C в течение 10-30 мин.
5. Композиция по п.1, которая содержит количество нереплицирующихся B.longum NCC 2705 CNCM 1-2618, соответствующее диапазону от около 104 до 1012 КОЕ на ежедневную дозу.
6. Композиция по п.1, которая содержит около 0,005-1000 мг нереплицирующихся B.longum NCC 2705 CNCM 1-2618 на ежедневную дозу.
7. Композиция по п.1, в которой, по меньшей мере, 95% B.longum NCC 2705 CNCM 1-2618 являются нереплицирующимися, предпочтительно все B.longum NCC 2705 CNCM 1-2618 являются нереплицирующимися.
8. Композиция по любому из предшествующих пунктов, которая выбрана из группы, состоящей из пищевых композиций, пищевых продуктов, включая пищу для домашних животных, напитков, диетических смесей, питательных смесей, нутрицевтиков, биологически активных добавок к пище, фармацевтических композиций, косметических композиций, композиций для местного применения и лекарственных средств.
9. Композиция по п.1, в которой расстройство, связанное с иммунной системой, выбирают из группы, состоящей из инфекций, в частности из бактериальной, вирусной, грибковой и/или паразитарной инфекций; фагоцитарных недостаточностей, дефекта эпителиального барьера или незрелости иммунной системы, избыточного бактериального роста в тонкой кишке (ИБРТК) и их комбинаций.
10. Композиция по п.1, в которой расстройство, связанное с иммунной системой, выбирают из группы расстройств, связанных со сниженным уровнем дефенсинов, в частности hBD2.
11. Композиция по п.10, в которой расстройство, связанное со сниженным уровнем hBD2, выбирают из группы, состоящей из кистозного фиброза, раздражения дыхательных путей, инфекций легких из-за курения табака, астмы, пневмонии, ринита, отита, синусита, туберкулеза, болезни Крона (толстой и подвздошной кишки), неспецифического язвенного колита, кишечной незрелости, гастрита и язвы желудка индуцированных инфекцией Helicobacter pylori, инфекционной диареи, некротизирующего энтероколита, антибиотик-ассоциированной диареи, бактериального вагиноза, ВИЧ, вируса простого герпеса, инфекции мочевыводящих путей, атопического дерматита, хронической язвы, карциномы, атопической экземы, ожогов, ангины, воспаления десен, кариеса зубов, кератита глаз.
12. Композиция по п.1, которую применяют для усиления эндогенной противомикробной защиты и/или эндогенной экспрессии hBD2 и hBD1.
13. Способ повышения эффективности В.longum NCC 2705 CNCM 1-2618 при лечении или при профилактике расстройств, связанных с иммунной системой, включающий стадию приведения B.longum NCC 2705 CNCM 1-2618 в нереплицирующееся состояние.
14. Способ по п.13, в котором В.longum NCC 2705 CNCM 1-2618 приведен в нереплицирующееся состояние на стадии тепловой обработки, по меньшей мере, при 75°C в течение, по меньшей мере, около 10 с.
15. Композиция, содержащая B.longum NCC 2705 CNCM 1-2618, в которой, по меньшей мере, 95%, предпочтительно, по меньшей мере, 98%, наиболее предпочтительно, по меньшей мере, 99%, в идеале, по меньшей мере, 99,9% или 100% B.longum NCC 2705 CNCM 1-2618 являются нереплицирующимися.
RU2011150214/15A 2009-05-11 2010-05-07 Bifidobacterium longum NCC 2705 (CNCM 1-2618) И ИММУННЫЕ РАССТРОЙСТВА RU2554772C2 (ru)

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