RU2008122166A - PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF UROGENITAL INFECTIONS - Google Patents
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF UROGENITAL INFECTIONS Download PDFInfo
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- RU2008122166A RU2008122166A RU2008122166/15A RU2008122166A RU2008122166A RU 2008122166 A RU2008122166 A RU 2008122166A RU 2008122166/15 A RU2008122166/15 A RU 2008122166/15A RU 2008122166 A RU2008122166 A RU 2008122166A RU 2008122166 A RU2008122166 A RU 2008122166A
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- Prior art keywords
- component
- pharmaceutical composition
- composition according
- extract
- lactic acid
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 14
- 208000015181 infectious disease Diseases 0.000 title claims abstract 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract 8
- 230000000843 anti-fungal effect Effects 0.000 claims abstract 6
- 230000002421 anti-septic effect Effects 0.000 claims abstract 6
- 229940121375 antifungal agent Drugs 0.000 claims abstract 6
- 239000000284 extract Substances 0.000 claims abstract 6
- 235000014655 lactic acid Nutrition 0.000 claims abstract 6
- 239000004310 lactic acid Substances 0.000 claims abstract 6
- 230000003444 anaesthetic effect Effects 0.000 claims abstract 5
- 210000001215 vagina Anatomy 0.000 claims abstract 5
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims abstract 4
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract 4
- 239000011668 ascorbic acid Substances 0.000 claims abstract 4
- 229960005070 ascorbic acid Drugs 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 4
- 235000010378 sodium ascorbate Nutrition 0.000 claims abstract 4
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims abstract 4
- 229960005055 sodium ascorbate Drugs 0.000 claims abstract 4
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims abstract 4
- 239000000654 additive Substances 0.000 claims abstract 3
- 230000000996 additive effect Effects 0.000 claims abstract 3
- 235000015872 dietary supplement Nutrition 0.000 claims abstract 3
- 239000000829 suppository Substances 0.000 claims abstract 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims abstract 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims abstract 2
- 235000004866 D-panthenol Nutrition 0.000 claims abstract 2
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract 2
- 239000011703 D-panthenol Substances 0.000 claims abstract 2
- 241000196324 Embryophyta Species 0.000 claims abstract 2
- 241000195955 Equisetum hyemale Species 0.000 claims abstract 2
- 241000208680 Hamamelis mollis Species 0.000 claims abstract 2
- ABSPRNADVQNDOU-UHFFFAOYSA-N Menaquinone 1 Natural products C1=CC=C2C(=O)C(CC=C(C)C)=C(C)C(=O)C2=C1 ABSPRNADVQNDOU-UHFFFAOYSA-N 0.000 claims abstract 2
- 241001465754 Metazoa Species 0.000 claims abstract 2
- 244000274883 Urtica dioica Species 0.000 claims abstract 2
- 235000009108 Urtica dioica Nutrition 0.000 claims abstract 2
- JQQZCIIDNVIQKO-UHFFFAOYSA-N benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC1=CC=CC=C1 JQQZCIIDNVIQKO-UHFFFAOYSA-N 0.000 claims abstract 2
- 229940119217 chamomile extract Drugs 0.000 claims abstract 2
- 235000020221 chamomile extract Nutrition 0.000 claims abstract 2
- 229960003260 chlorhexidine Drugs 0.000 claims abstract 2
- 229960003949 dexpanthenol Drugs 0.000 claims abstract 2
- 229960003255 natamycin Drugs 0.000 claims abstract 2
- 235000010298 natamycin Nutrition 0.000 claims abstract 2
- 239000004311 natamycin Substances 0.000 claims abstract 2
- NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 claims abstract 2
- 229920000847 nonoxynol Polymers 0.000 claims abstract 2
- 150000003904 phospholipids Chemical class 0.000 claims abstract 2
- MBWXNTAXLNYFJB-NKFFZRIASA-N phylloquinone Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C)C(=O)C2=C1 MBWXNTAXLNYFJB-NKFFZRIASA-N 0.000 claims abstract 2
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims abstract 2
- 235000019175 phylloquinone Nutrition 0.000 claims abstract 2
- 239000011772 phylloquinone Substances 0.000 claims abstract 2
- 229960001898 phytomenadione Drugs 0.000 claims abstract 2
- 229940108325 retinyl palmitate Drugs 0.000 claims abstract 2
- 235000019172 retinyl palmitate Nutrition 0.000 claims abstract 2
- 239000011769 retinyl palmitate Substances 0.000 claims abstract 2
- 229940042585 tocopherol acetate Drugs 0.000 claims abstract 2
- 229940118846 witch hazel Drugs 0.000 claims abstract 2
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims 2
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims 1
- MPIPASJGOJYODL-SFHVURJKSA-N (R)-isoconazole Chemical compound ClC1=CC(Cl)=CC=C1[C@@H](OCC=1C(=CC=CC=1Cl)Cl)CN1C=NC=C1 MPIPASJGOJYODL-SFHVURJKSA-N 0.000 claims 1
- LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229960005274 benzocaine Drugs 0.000 claims 1
- 229960003913 econazole Drugs 0.000 claims 1
- 229960004849 isoconazole Drugs 0.000 claims 1
- 229960004125 ketoconazole Drugs 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
- 229960002409 mepivacaine Drugs 0.000 claims 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 claims 1
- 229960002509 miconazole Drugs 0.000 claims 1
- 229960000988 nystatin Drugs 0.000 claims 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 claims 1
- 229960004919 procaine Drugs 0.000 claims 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
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- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1. Фармацевтическая композиция для лечения урогенитальных инфекций, содержащая антисептический компонент, биологически активную добавку, компонент, обеспечивающий естественную кислотность влагалища, и основу, отличающаяся тем, что она дополнительно содержит противогрибковый компонент и анестетик и выполнена в виде суппозитория при следующем соотношении компонентов, мас.%: ! Антисептический компонентне более 0,67Биологически активная добавкане более 16,67Компонент, обеспечивающий естественную кислотность влагалищане более 16,67Противогрибковый компонентне более 20,0Анестетикне более 16,67Основадо 100 ! 2. Фармацевтическая композиция по п.1, отличающаяся тем, что она в качестве антисептического компонента содержит хлоргексидина биглюконат, или ноноксинол, или мирамистин. ! 3. Фармацевтическая композиция по п.1, отличающаяся тем, что она в качестве биологически активной добавки, наряду с декспантенолом, или токоферола ацетатом, или экстрактом ромашки, может также содержать фосфолипид растительного или животного происхождения, или ретинола пальмитат, или филлохинон, или экстракт хвоща, или экстракт гамамелиса, или экстракт крапивы. ! 4. Фармацевтическая композиция по п.1, отличающаяся тем, что она в качестве компонента, обеспечивающего естественную кислотность влагалища, наряду с молочной кислотой, может также содержать аскорбиновую кислоту, или аскорбат натрия, или смесь молочной кислоты и аскорбиновой кислоты в соотношении 1:1, или смесь молочной кислоты и аскорбата натрия в соотношении 1:1. ! 5. Фармацевтическая композиция по п.1, отличающаяся тем, что в качестве противогрибкового компонента она содержит натамицин, и�1. A pharmaceutical composition for the treatment of urogenital infections, containing an antiseptic component, a biologically active additive, a component that provides the natural acidity of the vagina, and a base, characterized in that it additionally contains an antifungal component and anesthetic and is made in the form of a suppository in the following ratio of components, wt. %:! Antiseptic component not more than 0.67 Biologically active additive more than 16.67 Component that provides the natural acidity of the vagina more than 16.67 Antifungal component not more than 20.0 Anesthetic more than 16.67 Basically 100! 2. The pharmaceutical composition according to claim 1, characterized in that it contains as an antiseptic component chlorhexidine bigluconate, or nonoxynol, or miramistin. ! 3. The pharmaceutical composition according to claim 1, characterized in that it, as a dietary supplement, along with dexpanthenol, or tocopherol acetate, or chamomile extract, may also contain a phospholipid of plant or animal origin, or retinol palmitate, or phylloquinone, or extract horsetail, or witch hazel extract, or nettle extract. ! 4. The pharmaceutical composition according to claim 1, characterized in that it, as a component providing the natural acidity of the vagina, along with lactic acid, may also contain ascorbic acid, or sodium ascorbate, or a mixture of lactic acid and ascorbic acid in a ratio of 1: 1 , or a mixture of lactic acid and sodium ascorbate in a ratio of 1: 1. ! 5. The pharmaceutical composition according to claim 1, characterized in that it contains natamycin as an antifungal component, and
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008122166/15A RU2401102C2 (en) | 2008-06-02 | 2008-06-02 | Pharmaceutical composition for treating urogenital infections |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008122166/15A RU2401102C2 (en) | 2008-06-02 | 2008-06-02 | Pharmaceutical composition for treating urogenital infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008122166A true RU2008122166A (en) | 2009-12-10 |
| RU2401102C2 RU2401102C2 (en) | 2010-10-10 |
Family
ID=41489087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008122166/15A RU2401102C2 (en) | 2008-06-02 | 2008-06-02 | Pharmaceutical composition for treating urogenital infections |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2401102C2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2486912C1 (en) * | 2012-06-25 | 2013-07-10 | Антон Евгеньевич Супрун | Agent for vaginal douche in first stage of treatment of vaginal thrush (vaginal yeast) |
| RU2486911C1 (en) * | 2012-06-25 | 2013-07-10 | Антон Евгеньевич Супрун | Agent for vaginal douche in phase of vaginal microflora recovery following treatment of bacterial vaginosis and vaginal thrush (vaginal yeast) |
| RU2486913C1 (en) * | 2012-06-25 | 2013-07-10 | Антон Евгеньевич Супрун | Agent for vaginal douche in first stage of treatment of bacterial vaginosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA27543C2 (en) * | 1995-09-14 | 2000-09-15 | Georgij Andreevich Golik | A biologically active preparation containing vinylene ethonium and decamethoxin |
| RU2308951C2 (en) * | 2005-08-18 | 2007-10-27 | Виктор Игоревич Высоков | Complex method for preventing vaginal dysbacteriosis (variants) |
-
2008
- 2008-06-02 RU RU2008122166/15A patent/RU2401102C2/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2401102C2 (en) | 2010-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20200603 |