RU2007118979A - PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLYTIC AND PROTEOLYTIC ENZYMES - Google Patents
PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLYTIC AND PROTEOLYTIC ENZYMES Download PDFInfo
- Publication number
- RU2007118979A RU2007118979A RU2007118979/15A RU2007118979A RU2007118979A RU 2007118979 A RU2007118979 A RU 2007118979A RU 2007118979/15 A RU2007118979/15 A RU 2007118979/15A RU 2007118979 A RU2007118979 A RU 2007118979A RU 2007118979 A RU2007118979 A RU 2007118979A
- Authority
- RU
- Russia
- Prior art keywords
- proxanol
- polyethylene oxide
- purified water
- preparation according
- ratio
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title claims 24
- 108091005804 Peptidases Proteins 0.000 title claims 2
- 102000035195 Peptidases Human genes 0.000 title claims 2
- 230000001420 bacteriolytic effect Effects 0.000 title claims 2
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 title claims 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 34
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 32
- 239000008213 purified water Substances 0.000 claims 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 24
- 239000002953 phosphate buffered saline Substances 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 18
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims 17
- -1 for example Proteins 0.000 claims 17
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 15
- 229960004063 propylene glycol Drugs 0.000 claims 14
- 239000004698 Polyethylene Substances 0.000 claims 12
- 229920000573 polyethylene Polymers 0.000 claims 12
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 6
- 229920002385 Sodium hyaluronate Polymers 0.000 claims 6
- 229920002674 hyaluronan Polymers 0.000 claims 6
- 229960003160 hyaluronic acid Drugs 0.000 claims 6
- 229940010747 sodium hyaluronate Drugs 0.000 claims 6
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 5
- 239000003589 local anesthetic agent Substances 0.000 claims 5
- 239000000654 additive Substances 0.000 claims 4
- 239000002552 dosage form Substances 0.000 claims 4
- 239000008055 phosphate buffer solution Substances 0.000 claims 4
- 230000000996 additive effect Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 239000003995 emulsifying agent Substances 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- 235000019271 petrolatum Nutrition 0.000 claims 2
- CEYGNZMCCVVXQW-UHFFFAOYSA-N phosphoric acid;propane-1,2-diol Chemical compound CC(O)CO.OP(O)(O)=O CEYGNZMCCVVXQW-UHFFFAOYSA-N 0.000 claims 2
- VEPZOLKTNZOTTQ-UHFFFAOYSA-N 1-butyl-n-(2,4,6-trimethylphenyl)pyrrolidine-2-carboxamide Chemical compound CCCCN1CCCC1C(=O)NC1=C(C)C=C(C)C=C1C VEPZOLKTNZOTTQ-UHFFFAOYSA-N 0.000 claims 1
- CRWIVQWPUFWSCJ-UHFFFAOYSA-N 2-[(6-amino-7h-purin-8-yl)amino]ethanol Chemical compound NC1=NC=NC2=C1NC(NCCO)=N2 CRWIVQWPUFWSCJ-UHFFFAOYSA-N 0.000 claims 1
- YUXPJMWDDQCARU-UHFFFAOYSA-N 2-[bis(2-hydroxyethyl)amino]ethanol;2-(2-methylphenoxy)acetic acid Chemical compound OCCN(CCO)CCO.CC1=CC=CC=C1OCC(O)=O YUXPJMWDDQCARU-UHFFFAOYSA-N 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- 239000004264 Petrolatum Substances 0.000 claims 1
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims 1
- 229960002079 calcium pantothenate Drugs 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 229960001747 cinchocaine Drugs 0.000 claims 1
- PUFQVTATUTYEAL-UHFFFAOYSA-N cinchocaine Chemical compound C1=CC=CC2=NC(OCCCC)=CC(C(=O)NCCN(CC)CC)=C21 PUFQVTATUTYEAL-UHFFFAOYSA-N 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000002727 hyperosmolar Effects 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
- 108010013286 lysoamidase Proteins 0.000 claims 1
- XBCXJKGHPABGSD-UHFFFAOYSA-N methyluracil Natural products CN1C=CC(=O)NC1=O XBCXJKGHPABGSD-UHFFFAOYSA-N 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 229940066842 petrolatum Drugs 0.000 claims 1
- 239000008363 phosphate buffer Substances 0.000 claims 1
- 235000013772 propylene glycol Nutrition 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 claims 1
- 229950002569 trimecaine Drugs 0.000 claims 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (23)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007118979/15A RU2367456C2 (en) | 2007-05-23 | 2007-05-23 | Antibacterial and necrolytic local pharmaceutical composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007118979/15A RU2367456C2 (en) | 2007-05-23 | 2007-05-23 | Antibacterial and necrolytic local pharmaceutical composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007118979A true RU2007118979A (en) | 2008-11-27 |
| RU2367456C2 RU2367456C2 (en) | 2009-09-20 |
Family
ID=41168132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007118979/15A RU2367456C2 (en) | 2007-05-23 | 2007-05-23 | Antibacterial and necrolytic local pharmaceutical composition |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2367456C2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012013812A2 (en) * | 2009-12-08 | 2018-05-29 | Healthpoint Ltd | "enzymatic debridement compositions of wounds with enhanced enzyme activity" |
| RU2655808C2 (en) * | 2016-10-11 | 2018-05-29 | Закрытое Акционерное Общество "Биологические Исследования И Системы" (Зао "Бис") | Pharmaceutical combined composition for local and external use on basis of bacteriolytic and proteolytic complex of enzymes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2161959C2 (en) * | 1996-11-01 | 2001-01-20 | Далгатов Гимат Далгатович | Method for preventing connective tissue adhesion |
| RU2139348C1 (en) * | 1997-10-06 | 1999-10-10 | Институт биохимии и физиологии микроорганизмов им.Г.К.Скрябина РАН | Agent for lysis of cells of gram-positive and gram-negative microorganisms |
| RU2195262C2 (en) * | 1999-08-13 | 2002-12-27 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Hyaluronic acid-base pharmacological agent showing antibacterial, wound-healing and anti-inflammatory effect |
| RU2200565C1 (en) * | 2001-06-29 | 2003-03-20 | Всероссийский научно-исследовательский институт ветеринарной санитарии, гигиены и экологии | Preparation for treating mastitis in cattle during lactation period |
-
2007
- 2007-05-23 RU RU2007118979/15A patent/RU2367456C2/en active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2367456C2 (en) | 2009-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2314049T3 (en) | LIQUID FORMULATIONS FOR THE PREVENTION AND TREATMENT OF MUCOSA DISEASES AND DISORDERS. | |
| ES8500738A1 (en) | A PROCEDURE FOR THE PREPARATION OF A TOPIC ANTI-INFLAMMATORY COMPOSITION AS AN OIL IN THE FORM OF GEL | |
| ECSP055890A (en) | TETRAHIDRO-4H-PIRIDO [1,2-a] PIRIMIDINES AND RELATED COMPOUNDS USEFUL AS INHIBITORS OF HIV INTEGRESS | |
| AR037490A1 (en) | SOLID PHARMACEUTICAL COMPOSITIONS, PROCESS FOR PREPARATION, KIT FOR THE TREATMENT OF OBESITY AND USE OF SUCH COMPOSITIONS IN THE DEVELOPMENT OF MEDICINES | |
| WO2005039498A3 (en) | Methods of treating cancer with hdac inhibitors | |
| MY137060A (en) | Topical pharmaceutical compositions comprising proanthocyanidins, glycyrrhetinic acid and telmesteine for the treatment of dermatitis | |
| RU2014146985A (en) | NEW MEDICINES FOR LOCAL USE ON THE BASIS OF SULPHATED HYALURONIC ACID AS STIMULATORS OR INHIBITORS OF CYTOKINE ACTIVITY | |
| US20050287219A1 (en) | Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same | |
| ATE418970T1 (en) | PHARMACEUTICAL COMPOSITIONS - CONTAINING PH-SENSITIVE BLOCK COPOLYMERS AND A HYDROPHOBIC ACTIVE INGREDIENT | |
| EA200601654A1 (en) | HIV INTEGRASE INHIBITORS | |
| MY173582A (en) | Extended-release formulation for reducing the frequency of urination and method of use thereof | |
| RU2007148444A (en) | PEDIATRIC TOPIRAMAT COMPOSITION | |
| RU2019140862A (en) | VARIANTS OF SULPHAMIDASE (SGSH), VECTORS, COMPOSITIONS AND METHODS AND APPLICATIONS FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS TYPE IIIA (MPS IIIA) | |
| RU2012109392A (en) | PHARMACEUTICAL COMPOSITION FOR REDUCING PAIN | |
| RU2007118979A (en) | PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLYTIC AND PROTEOLYTIC ENZYMES | |
| RU2007118971A (en) | PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLOGICAL AND PROTEOLYTIC ENZYMES | |
| CN101524363A (en) | Artificial saliva | |
| RU2007118984A (en) | PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLYTIC AND PROTEOLYTIC ENZYMES | |
| MXPA05008403A (en) | Use of edible acid in fast-dispersing pharmaceutical solid dosage forms. | |
| SI21079B (en) | Formulation having mobilising activity | |
| RU2007118975A (en) | PHARMACOLOGICAL PRODUCT FOR LOCAL APPLICATION BASED ON THE COMPLEX OF BACTERIOLOGICAL AND PROTEOLYTIC ENZYMES | |
| HRP20050342B1 (en) | OLANZAPINE PHARMACEUTICAL FORMULATION | |
| RU2018125252A (en) | Synergistic combination of pyrrolidone-carboxylic acid and / or its salts and hyaluronic acid and / or its salts for use in the treatment and / or prevention of dryness and irritation of mucous membranes | |
| CN103211755A (en) | Production method of sterile stable azithromycin eye drops | |
| RU2006131812A (en) | PHARMACEUTICAL COMPOSITION OF ANTI-INFLAMMATORY AND ANTIMICROBIC ACTION IN THE FORM OF OILS ON A HYDROPHOBIC BASIS FOR TREATMENT OF SKIN DISEASES (OPTIONS) |