RU1832031C - Method of treatment of intestine infection of proteus etiology - Google Patents

Abstract

The invention relates to medicine and relates to a method for treating an intestinal infection of a proteic etiology. The purpose of the invention is. No reduction in treatment time. The invention consists in the introduction simultaneously with antibacterial drugs and methyluracil of splenin and decoction of St. John's wort, root and rhizome of the bloodlet and rhizome of the cinquefoil, taken in the ratio, wt.%: 2.5: 1.5: 1.0 and water to 100 50-100 ml 3 times a day for 5-7 days. The positive effect is to reduce the treatment time from 11 to 8 days. 1 tab.

Description

The invention relates to the field of medicine and relates to methods for treating infectious diseases.

The aim of the invention is to reduce the treatment time for acute intestinal infection of proteic etiology.

This goal is achieved by the fact that, in addition to antibacterial drugs, saline solutions, vitamins, enzymes and methyluracil, 2 ml splenin is administered intramuscularly and inside a decoction of the following composition: 2.5 g of St. John's wort grass, 1.5 g of rhizome and root of the blood pot and 1 g rhizomes of cinquefoil in 100 ml of water up to 50-100 ml 3 times a day for 5-7 days.

This proposal is based on the results of clinical observations of the authors over 168 patients with intestinal infection of proteic etiology at the age of 32 to 65 years old with a diagnosis confirmed bacteriologically. All patients with intestinal infection were randomly divided into 2 groups, the first of which included 89

sick and second -.79. Patients of the first group received treatment in accordance with the proposed method, the second - according to the existing method (prototype).

Treatment in both groups included antibacterial drugs (primarily polymyxin), saline solutions, multivitamins, enzymes, and methyluracil. In the main group, in addition, 2 ml splenin was administered intramuscularly and inside a decoction of St. John's wort, rhizomes, and blood-root root and cinquefoil rhizomes, 50-100 ml 3 times a day.

Investigations carried out by the authors of the studies showed that it is the appointment of splenin that accelerates the elimination of symptoms of infectious toxicosis in patients and normalizes indicators of immune status.

The effect of prescribing a decoction of St. John's wort, rhizome and root of the bloodlet and root of the cinquefoil is a significant reduction in the duration

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diarrhea syndrome and accelerate the regeneration of the intestinal mucosa.

The results obtained when comparing the effectiveness of the existing and proposed methods of treating patients with intestinal infection of proteic etiology are presented in the table.

As a result of comparing the proposed and existing methods for treating intestinal infections of proteic etiology, it has been found that the proposed method has significant advantages in increasing the efficiency and accelerating the duration of the heat. Moreover, the duration of treatment of patients in the hospital is reduced by an average of 3.0 ± 0.3 days (.05).

The invention is illustrated by the following examples.

PRI me R 1. Patient K., 62 years old, a pensioner, became ill sharply, suddenly after eating meat salad, which was stored in the refrigerator for 2 days. Onset of the disease with a rise in temperature to 38.9 ° C, onset of nausea, repeated vomiting, pain in the zypastria and near the navel. She was hospitalized in an infectious diseases hospital where repeated vomiting was noted, repeated loose stools with mucus, with an unpleasant fetid odor. Vulgar protea was isolated from feces in the amount of 10 / g of feces,

Prescribed treatment with polymyxin 0.5 g 4 times a day, oral solution of Oralit, multivitamins Undevit, pancreatin, methyluracil 1.0 g 4 times a day, splenin 2 ml intramuscularly 1 time per day, decoction of St. John's wort, rhizomes and hemorrhagic root, cinquefoil rhizomes (2.5: 1.5: 1.0) per 100 ml of water / 50 ml 3 times a day. The treatment was carried out for 7 days.

Under the influence of the treatment, the patient's condition quickly improved. The duration of the fever was 4 days, the weakness also persisted for 4 days, the decrease in appetite disappeared on the 5th day, and nausea on the 3rd day. The duration of diarrhea was 3 days, abdominal pain - 3 days. An admixture of mucus in the stool disappeared on the 4th day. With repeated bacteriological examination, the pathogen was not isolated. The level of T-lymphocytes on the 8th day of the treatment was 51%, and the CEC was 2.3 g / l. The duration of inpatient treatment was 8 days. In the study, the dynamics showed an increase in the titer in the agglutination reaction with the auto strain prote from 1:50 to 1: 200 (4 times). A definitive diagnosis: acute intestinal infection of proteic etiology, gastroenteric variant, moderate yellow course.

Discharged home in satisfactory condition, clinically healthy.

Example 2. Sick N., 48 years old. a nurse. Suffers from drug allergy to penicillin, novocaine. For exacerbation of chronic pneumonia, she received antibiotics for a long time. Periodically worries

diarrhea. The present disease began sharply, suddenly, with an increase in temperature to 39.1 ° C, due to nausea, repeated vomiting, abdominal pain, and loose stools. Epidemiologically, the disease is associated with

5 eating stale rumble sha. There was vomiting with an admixture of bile, multiple loose stools with a fetid odor and an admixture of mucus. On palpation, abdominal pain was noted - epigastric and umbilical

0 area. Vulgar protea was isolated from feces in the amount of 109 / g of feces.

Prescribed treatment in accordance with the sensitivity of the culture of prote ampicillin 0.5 g 4 times a day, inside

5 saline solution Oralit, multivitamins Decamevit, pancreatin, methyluracil 0.5 g 4 times a day, splenin 2 ml intramuscularly, decoction of St. John's wort, rhizome and root of the bloodlet, root rhizome

0 to 100 ml 3 times a day. The treatment was carried out for 5 days.

Under the influence of the treatment, the patient's condition improved significantly. The duration of the fever was 5 days, weakness and loss of appetite disappeared on the 4th day, and nausea on the 2nd day. The duration of diarrheal syndrome was 3 days, abdominal pain disappeared on the 3rd day, an admixture of mucus in the stool on the 4th

0 day. With repeated bacteriological investigation, the pathogen was not detected. The level of T cells on the 8th day of treatment was 52%, CK-2.2 g / L. The duration of treatment in the hospital is 8 days.

5 During the study, a 4-fold increase in the titer in the agglutination reaction with the auto-strain prote was noted in dynamics. Final diagnosis: acute intestinal infection of proteic etiology, gastroenteric variant, moderate yellow course. Discharged home in satisfactory condition, clinically healthy.

Thus, the proposed method for the treatment of acute intestinal infection of proteic etiology has advantages over the existing one, consisting in accelerating the time of recovery of patients. The technical method is simple, does not require scarce and expensive medicines and imported drugs, and can be carried out in

conditions of medical institutions of both city and district level, as well as, if necessary, and outpatient practice. The method is well tolerated by patients and does not cause adverse reactions.

Claims (1)

SUMMARY OF THE INVENTION A method for treating an intestinal infection of a proteic etiology by administering antibacterial drugs, saline solutions, vitamins, enzymes and methyluracil, characterized in that, in order to shorten the treatment time, they additionally introduce splenin, 2 ml intramuscularly and inside, a decoction of St. John's wort grass, rhizome and root of the bloodlet, root of the cinquefoil in the following ratio of components, wt.%: St. John's wort grass 2.5 rhizome and root of the hemophilus 1.5 water up to 100 50-100 ml 3 times a day for 5-7 days.