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PT975638E - Epothilons modificados nas cadeias laterais - Google Patents

Epothilons modificados nas cadeias laterais

Info

Publication number
PT975638E
PT975638E PT98912388T PT98912388T PT975638E PT 975638 E PT975638 E PT 975638E PT 98912388 T PT98912388 T PT 98912388T PT 98912388 T PT98912388 T PT 98912388T PT 975638 E PT975638 E PT 975638E
Authority
PT
Portugal
Prior art keywords
epothilons
modified
lateral chains
chains
lateral
Prior art date
Application number
PT98912388T
Other languages
English (en)
Inventor
Hofle Prof Dr Gerhard
Michael Sefkow
Original Assignee
Biotechnolog Forschung Mbh Gbf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotechnolog Forschung Mbh Gbf filed Critical Biotechnolog Forschung Mbh Gbf
Publication of PT975638E publication Critical patent/PT975638E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Epoxy Compounds (AREA)
  • Silicon Polymers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98912388T 1997-02-25 1998-02-25 Epothilons modificados nas cadeias laterais PT975638E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19707505 1997-02-25

Publications (1)

Publication Number Publication Date
PT975638E true PT975638E (pt) 2002-12-31

Family

ID=7821415

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98912388T PT975638E (pt) 1997-02-25 1998-02-25 Epothilons modificados nas cadeias laterais

Country Status (24)

Country Link
US (1) US6359140B1 (pt)
EP (2) EP0975638B1 (pt)
JP (1) JP2001513098A (pt)
KR (1) KR100494179B1 (pt)
CN (2) CN1544436A (pt)
AR (1) AR011878A1 (pt)
AT (1) ATE221888T1 (pt)
AU (1) AU736062B2 (pt)
BR (1) BR9807742B1 (pt)
CA (1) CA2281105A1 (pt)
CZ (1) CZ298027B6 (pt)
DE (2) DE19880193D2 (pt)
DK (1) DK0975638T3 (pt)
ES (1) ES2183338T3 (pt)
HU (1) HU228851B1 (pt)
IL (1) IL131343A (pt)
NO (1) NO327211B1 (pt)
NZ (1) NZ337195A (pt)
PL (1) PL190422B1 (pt)
PT (1) PT975638E (pt)
RU (1) RU2201932C2 (pt)
TW (1) TW480263B (pt)
WO (1) WO1998038192A1 (pt)
ZA (1) ZA981575B (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
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JP4579351B2 (ja) 1996-12-03 2010-11-10 スローン−ケッタリング インスティトュート フォア キャンサー リサーチ エポチロンの合成とその中間体及びその類似物並びにその使用
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US20050043376A1 (en) * 1996-12-03 2005-02-24 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6380394B1 (en) 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
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US6660758B1 (en) 1996-12-13 2003-12-09 The Scripps Research Institute Epothilone analogs
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US6365749B1 (en) 1997-12-04 2002-04-02 Bristol-Myers Squibb Company Process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
US6320045B1 (en) 1997-12-04 2001-11-20 Bristol-Myers Squibb Company Process for the reduction of oxiranyl epothilones to olefinic epothilones
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
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Family Cites Families (4)

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DE4138042C2 (de) * 1991-11-19 1993-10-14 Biotechnolog Forschung Gmbh Epothilone, deren Herstellungsverfahren sowie diese Verbindungen enthaltende Mittel
PT873341E (pt) * 1995-11-17 2004-02-27 Biotechnolog Forschung Mbh Gbf Derivados de epotilona preparacao e utilizacao
US6441186B1 (en) * 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
HU228851B1 (en) * 1997-02-25 2013-06-28 Biotechnolog Forschung Gmbh Process for preparing epothilones with a modified side chain and compounds prepared by this process

Also Published As

Publication number Publication date
AU6724998A (en) 1998-09-18
ATE221888T1 (de) 2002-08-15
US6359140B1 (en) 2002-03-19
EP1201666A2 (de) 2002-05-02
CZ298027B6 (cs) 2007-05-30
PL190422B1 (pl) 2005-12-30
DE19880193D2 (de) 2000-08-24
CA2281105A1 (en) 1998-09-03
EP0975638A1 (de) 2000-02-02
BR9807742B1 (pt) 2010-12-14
HUP0002189A3 (en) 2001-12-28
JP2001513098A (ja) 2001-08-28
CZ286599A3 (cs) 2000-03-15
HU228851B1 (en) 2013-06-28
AU736062B2 (en) 2001-07-26
PL335329A1 (en) 2000-04-25
KR20000075705A (ko) 2000-12-26
NZ337195A (en) 2001-05-25
EP0975638B1 (de) 2002-08-07
CN1248974A (zh) 2000-03-29
AR011878A1 (es) 2000-09-13
TW480263B (en) 2002-03-21
NO994071L (no) 1999-10-21
CN1128803C (zh) 2003-11-26
ZA981575B (en) 1998-09-08
HK1023774A1 (en) 2000-09-22
WO1998038192A1 (de) 1998-09-03
CN1544436A (zh) 2004-11-10
DE59805110D1 (de) 2002-09-12
EP1201666A3 (de) 2003-03-05
BR9807742A (pt) 2000-02-22
NO327211B1 (no) 2009-05-11
KR100494179B1 (ko) 2005-06-10
HUP0002189A2 (hu) 2001-10-28
NO994071D0 (no) 1999-08-24
ES2183338T3 (es) 2003-03-16
IL131343A (en) 2004-03-28
DK0975638T3 (da) 2002-11-18
IL131343A0 (en) 2001-01-28
RU2201932C2 (ru) 2003-04-10

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