MX2009005849A - Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas. - Google Patents
Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas.Info
- Publication number
- MX2009005849A MX2009005849A MX2009005849A MX2009005849A MX2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- cancer
- aeruginosa
- present
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 6
- 201000011510 cancer Diseases 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108010007337 Azurin Proteins 0.000 abstract 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract 2
- 108010092351 cupredoxin Proteins 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a composiciones que comprenden ADN rico en CpG a partir de Pseudomonas aeruginosa. Las composiciones opcionalmente comprenden una cupredoxina. La presente invención incluye ADNs de CpG específicos apartir de Pseudomonas aeruginosa, que son empledos para tratarcáncer y otras condiciones en pacientes. Estas composiciones están opcionalmente en un portador farmacéuticamente aceptable y también comprendenopcionalmente una cupredoxina. La presente invención además se refiere a métodos para expresar proteínas cerca de células de cáncer. Estos métodos pueden ser usados para expresarproteínas de diagnósticas cerca de células de cáncer en un paciente que sufre de cáncer u otras condiciones, y también pueden ser usados pára diagnosticar cáncer en un paciente. Este método usa el gen de azurina a partir de P. aeruginosa como un sistema de expresión para azurina o proteínas heterólogas en P. aeruginosa células hetrólogas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87247106P | 2006-12-04 | 2006-12-04 | |
| PCT/US2007/086393 WO2008070672A2 (en) | 2006-12-04 | 2007-12-04 | Compositions and methods to treat cancer with cupredoxins and cpg rich dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009005849A true MX2009005849A (es) | 2009-08-12 |
Family
ID=39493039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009005849A MX2009005849A (es) | 2006-12-04 | 2007-12-04 | Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8017749B2 (es) |
| EP (1) | EP2089411A4 (es) |
| JP (2) | JP2010511408A (es) |
| KR (1) | KR20090095626A (es) |
| CN (1) | CN101600728A (es) |
| AU (1) | AU2007329375A1 (es) |
| BR (1) | BRPI0718360A2 (es) |
| CA (1) | CA2671492A1 (es) |
| MX (1) | MX2009005849A (es) |
| NO (1) | NO20092522L (es) |
| RU (1) | RU2009125599A (es) |
| WO (2) | WO2008070666A2 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6977245B2 (en) * | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| WO2000061151A2 (en) | 1999-04-12 | 2000-10-19 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US20030129251A1 (en) * | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| US7381701B2 (en) | 2001-02-15 | 2008-06-03 | The Borad Of Trustees Of The University Of Illinois | Compositions and methods for treating conditions related to ephrin signaling with cupredoxins |
| US9096663B2 (en) * | 2001-02-15 | 2015-08-04 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof |
| US20030199466A1 (en) * | 2001-06-21 | 2003-10-23 | Fearon Karen L. | Chimeric immunomodulatory compounds and methods of using the same - ll |
| CN101948835A (zh) * | 2002-10-29 | 2011-01-19 | 科勒制药集团股份有限公司 | Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用 |
| CA2536139A1 (en) * | 2003-09-25 | 2005-04-07 | Coley Pharmaceutical Group, Inc. | Nucleic acid-lipophilic conjugates |
| US9598470B2 (en) * | 2004-10-07 | 2017-03-21 | Craig W. Beattie | Compositions and methods to prevent cancer by stabilizing P53 through non MDM2-mediated pathways |
| EP1797114A4 (en) * | 2004-10-07 | 2009-07-15 | Ananda Chakrabarty | CUPREDOXIN-DERIVED TRANSPORT AGENTS AND METHODS OF USE |
| WO2008070666A2 (en) * | 2006-12-04 | 2008-06-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods to treat cancer with cpg rich dna and cupredoxins |
| RU2009133473A (ru) * | 2007-02-08 | 2011-03-20 | Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Иллинойс (Us) | Композиции и способы для предотвращения рака с помощью купредоксинов |
| PE20110998A1 (es) | 2008-12-09 | 2012-02-10 | Coley Pharm Group Inc | Oligonucleotidos inmunoestimuladores |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| WO2014049604A2 (en) * | 2012-09-05 | 2014-04-03 | Amrita Therapeutics Limited | A novel biomedical device for cancer therapy |
| MX2015007794A (es) * | 2012-12-21 | 2015-09-04 | Teva Pharma | Suministro transmucosal de acetato de glatiramer mediante parches orales. |
| EP3115039B1 (de) * | 2015-07-09 | 2021-12-15 | beniag GmbH | Verfahren zum herstellen einer fusionsmischung zur übertragung eines geladenen moleküls in und/oder durch eine lipidmembran |
| RU204475U1 (ru) * | 2020-09-24 | 2021-05-26 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова" (ФГБНУ "НИИ МТ") | Медицинский аппликатор для местного лечения кожных заболеваний |
| CN119367528A (zh) * | 2024-10-25 | 2025-01-28 | 重庆医科大学附属第二医院 | 联合CpG-ODN佐剂的铜绿假单胞菌DNA疫苗的制备方法及应用 |
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| US7301010B2 (en) * | 2001-02-15 | 2007-11-27 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating HIV infection with cupredoxin and cytochrome c |
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| US8685720B2 (en) * | 2006-11-03 | 2014-04-01 | The Trustees Of Princeton University | Engineered cellular pathways for programmed autoregulation of differentiation |
| WO2008070666A2 (en) * | 2006-12-04 | 2008-06-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods to treat cancer with cpg rich dna and cupredoxins |
| RU2009133473A (ru) * | 2007-02-08 | 2011-03-20 | Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Иллинойс (Us) | Композиции и способы для предотвращения рака с помощью купредоксинов |
| WO2009078977A2 (en) * | 2007-12-14 | 2009-06-25 | Cdg Therapeutics Inc | Compositions and methods to concurrently treat or prevent multiple diseases with cupredoxins |
| JP5873499B2 (ja) * | 2010-10-01 | 2016-03-01 | アムリタ セラピューティクス リミテッドAmrita Therapeutics Limited | 抗がん剤 |
| PT2574597E (pt) * | 2011-09-30 | 2016-02-08 | Elaflex Hiby Tanktechnik Gmbh & Co | Válvula de distribuição |
| WO2017012661A1 (en) * | 2015-07-22 | 2017-01-26 | Curetis Gmbh | Genetic testing for predicting resistance of pseudomonas species against antimicrobial agents |
| KR102024186B1 (ko) * | 2017-05-04 | 2019-09-23 | 주식회사 젠센 | 톨-유사 수용체(tlr) 억제를 위한 펩타이드 및 이를 포함하는 약학적 조성물 |
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2007
- 2007-12-04 WO PCT/US2007/086385 patent/WO2008070666A2/en not_active Ceased
- 2007-12-04 BR BRPI0718360-7A2A patent/BRPI0718360A2/pt not_active Application Discontinuation
- 2007-12-04 WO PCT/US2007/086393 patent/WO2008070672A2/en not_active Ceased
- 2007-12-04 US US11/950,165 patent/US8017749B2/en active Active
- 2007-12-04 AU AU2007329375A patent/AU2007329375A1/en not_active Abandoned
- 2007-12-04 EP EP07868980A patent/EP2089411A4/en not_active Withdrawn
- 2007-12-04 KR KR1020097013765A patent/KR20090095626A/ko not_active Withdrawn
- 2007-12-04 MX MX2009005849A patent/MX2009005849A/es active IP Right Grant
- 2007-12-04 CA CA002671492A patent/CA2671492A1/en not_active Abandoned
- 2007-12-04 JP JP2009540425A patent/JP2010511408A/ja active Pending
- 2007-12-04 RU RU2009125599/10A patent/RU2009125599A/ru not_active Application Discontinuation
- 2007-12-04 CN CNA2007800505771A patent/CN101600728A/zh active Pending
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2009
- 2009-07-03 NO NO20092522A patent/NO20092522L/no not_active Application Discontinuation
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2011
- 2011-09-12 US US13/230,055 patent/US9969781B2/en active Active
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2014
- 2014-04-10 JP JP2014081387A patent/JP2014158486A/ja active Pending
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2017
- 2017-12-11 US US15/837,066 patent/US11046733B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014158486A (ja) | 2014-09-04 |
| WO2008070672A3 (en) | 2009-04-16 |
| WO2008070672A2 (en) | 2008-06-12 |
| CA2671492A1 (en) | 2008-06-12 |
| BRPI0718360A2 (pt) | 2013-11-12 |
| CN101600728A (zh) | 2009-12-09 |
| US8017749B2 (en) | 2011-09-13 |
| WO2008070666A2 (en) | 2008-06-12 |
| WO2008070666A3 (en) | 2009-04-09 |
| US9969781B2 (en) | 2018-05-15 |
| US11046733B2 (en) | 2021-06-29 |
| US20120014877A1 (en) | 2012-01-19 |
| NO20092522L (no) | 2009-09-04 |
| US20200172581A1 (en) | 2020-06-04 |
| JP2010511408A (ja) | 2010-04-15 |
| EP2089411A2 (en) | 2009-08-19 |
| AU2007329375A2 (en) | 2009-08-13 |
| US20090226405A1 (en) | 2009-09-10 |
| EP2089411A4 (en) | 2010-01-27 |
| AU2007329375A1 (en) | 2008-06-12 |
| KR20090095626A (ko) | 2009-09-09 |
| RU2009125599A (ru) | 2011-01-20 |
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