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MX2009005849A - Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas. - Google Patents

Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas.

Info

Publication number
MX2009005849A
MX2009005849A MX2009005849A MX2009005849A MX2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A MX 2009005849 A MX2009005849 A MX 2009005849A
Authority
MX
Mexico
Prior art keywords
compositions
methods
cancer
aeruginosa
present
Prior art date
Application number
MX2009005849A
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English (en)
Inventor
Ananda Chakrabarty
Gupta Tapas Das
Original Assignee
Univ Illinois
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Application filed by Univ Illinois filed Critical Univ Illinois
Publication of MX2009005849A publication Critical patent/MX2009005849A/es

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a composiciones que comprenden ADN rico en CpG a partir de Pseudomonas aeruginosa. Las composiciones opcionalmente comprenden una cupredoxina. La presente invención incluye ADNs de CpG específicos apartir de Pseudomonas aeruginosa, que son empledos para tratarcáncer y otras condiciones en pacientes. Estas composiciones están opcionalmente en un portador farmacéuticamente aceptable y también comprendenopcionalmente una cupredoxina. La presente invención además se refiere a métodos para expresar proteínas cerca de células de cáncer. Estos métodos pueden ser usados para expresarproteínas de diagnósticas cerca de células de cáncer en un paciente que sufre de cáncer u otras condiciones, y también pueden ser usados pára diagnosticar cáncer en un paciente. Este método usa el gen de azurina a partir de P. aeruginosa como un sistema de expresión para azurina o proteínas heterólogas en P. aeruginosa células hetrólogas.
MX2009005849A 2006-12-04 2007-12-04 Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas. MX2009005849A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87247106P 2006-12-04 2006-12-04
PCT/US2007/086393 WO2008070672A2 (en) 2006-12-04 2007-12-04 Compositions and methods to treat cancer with cupredoxins and cpg rich dna

Publications (1)

Publication Number Publication Date
MX2009005849A true MX2009005849A (es) 2009-08-12

Family

ID=39493039

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005849A MX2009005849A (es) 2006-12-04 2007-12-04 Composiciones y metodos para tratar cancer con adn rico en cpg y cupredoxinas.

Country Status (12)

Country Link
US (3) US8017749B2 (es)
EP (1) EP2089411A4 (es)
JP (2) JP2010511408A (es)
KR (1) KR20090095626A (es)
CN (1) CN101600728A (es)
AU (1) AU2007329375A1 (es)
BR (1) BRPI0718360A2 (es)
CA (1) CA2671492A1 (es)
MX (1) MX2009005849A (es)
NO (1) NO20092522L (es)
RU (1) RU2009125599A (es)
WO (2) WO2008070666A2 (es)

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Also Published As

Publication number Publication date
JP2014158486A (ja) 2014-09-04
WO2008070672A3 (en) 2009-04-16
WO2008070672A2 (en) 2008-06-12
CA2671492A1 (en) 2008-06-12
BRPI0718360A2 (pt) 2013-11-12
CN101600728A (zh) 2009-12-09
US8017749B2 (en) 2011-09-13
WO2008070666A2 (en) 2008-06-12
WO2008070666A3 (en) 2009-04-09
US9969781B2 (en) 2018-05-15
US11046733B2 (en) 2021-06-29
US20120014877A1 (en) 2012-01-19
NO20092522L (no) 2009-09-04
US20200172581A1 (en) 2020-06-04
JP2010511408A (ja) 2010-04-15
EP2089411A2 (en) 2009-08-19
AU2007329375A2 (en) 2009-08-13
US20090226405A1 (en) 2009-09-10
EP2089411A4 (en) 2010-01-27
AU2007329375A1 (en) 2008-06-12
KR20090095626A (ko) 2009-09-09
RU2009125599A (ru) 2011-01-20

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