PT869955E - As n-acil-2-substituidas-4-(substituidas com residuos benzimidazolilo ou imidapiridinilo)-piperidinas como antagonistas das taquicininas - Google Patents

As n-acil-2-substituidas-4-(substituidas com residuos benzimidazolilo ou imidapiridinilo)-piperidinas como antagonistas das taquicininas

Info

Publication number: PT869955E
Authority: PT; Portugal
Prior art keywords: substituted; taquicinines; imidapyridinyl; piperidines; benzimidazolyl
Prior art date: 1995-12-27

Application number

PT96944686T

Other languages

English (en)

Inventor

Dominique Louis Nest Surleraux

Frans Eduard Janssens

Francois Maria Sommen

Joseph Elisabeth Leenaerts

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-27

Filing date

1996-12-20

Publication date

2002-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26139977&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT869955(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-12-20 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2002-04-29 Publication of PT869955E publication Critical patent/PT869955E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Immunology (AREA)
Virology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT96944686T 1995-12-27 1996-12-20 As n-acil-2-substituidas-4-(substituidas com residuos benzimidazolilo ou imidapiridinilo)-piperidinas como antagonistas das taquicininas PT869955E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95203650		1995-12-27
EP95203653		1995-12-27

Publications (1)

Publication Number	Publication Date
PT869955E true PT869955E (pt)	2002-04-29

Family

ID=26139977

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96944686T PT869955E (pt)	1995-12-27	1996-12-20	As n-acil-2-substituidas-4-(substituidas com residuos benzimidazolilo ou imidapiridinilo)-piperidinas como antagonistas das taquicininas

Country Status (26)

Country	Link
US (1)	US6110939A (pt)
EP (1)	EP0869955B1 (pt)
JP (1)	JP4177895B2 (pt)
KR (1)	KR100439846B1 (pt)
CN (1)	CN1117090C (pt)
AR (1)	AR005279A1 (pt)
AT (1)	ATE207484T1 (pt)
AU (1)	AU707116B2 (pt)
BR (1)	BR9612326A (pt)
CA (1)	CA2238816C (pt)
CZ (1)	CZ294199B6 (pt)
DE (1)	DE69616379T2 (pt)
DK (1)	DK0869955T3 (pt)
EA (1)	EA001247B1 (pt)
ES (1)	ES2166915T3 (pt)
HU (1)	HU227799B1 (pt)
MY (1)	MY121580A (pt)
NO (1)	NO313291B1 (pt)
NZ (1)	NZ325839A (pt)
PL (1)	PL184489B1 (pt)
PT (1)	PT869955E (pt)
SI (1)	SI0869955T1 (pt)
SK (1)	SK283533B6 (pt)
TR (1)	TR199801218T2 (pt)
TW (1)	TW429256B (pt)
WO (1)	WO1997024350A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5889006A (en) *	1995-02-23	1999-03-30	Schering Corporation	Muscarinic antagonists
TW531537B (en) *	1995-12-27	2003-05-11	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4-substituted piperidine derivatives
AU7788500A (en) *	1999-10-25	2001-05-08	Janssen Pharmaceutica N.V.	Use of substance p antagonists for influencing the circadian timing system
US8101629B2 (en)	2001-08-13	2012-01-24	Janssen Pharmaceutica N.V.	Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
JO3429B1 (ar)	2001-08-13	2019-10-20	Janssen Pharmaceutica Nv	مشتقات برميدينات مثبطة فيروس الايدز
AU2002356715B2 (en)	2001-11-23	2008-05-15	Janssen Pharmaceutica N.V.	The use of anti-histaminics for acute reduction of elevated intracranial pressure
US20040063744A1 (en) *	2002-05-28	2004-04-01	Tao Wang	Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides
US7348337B2 (en)	2002-05-28	2008-03-25	Bristol-Myers Squibb Company	Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides
AR044152A1 (es) *	2003-05-09	2005-08-24	Bayer Corp	Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad
JO2676B1 (en)	2004-04-06	2012-06-17	جانسين فارماسوتيكا ان. في	Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
US20060100432A1 (en)	2004-11-09	2006-05-11	Matiskella John D	Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
EA012421B1 (ru)	2005-03-03	2009-10-30	Янссен Фармацевтика Н. В.	Замещённые производные оксадиазаспиро[5.5]ундеканона и их применение в качестве антагонистов нейрокинина
CN101137657B (zh)	2005-03-08	2011-02-02	詹森药业有限公司	作为神经激肽（nk1）拮抗剂的二氮杂-螺-[4.4]-壬烷衍生物
US7807671B2 (en)	2006-04-25	2010-10-05	Bristol-Myers Squibb Company	Diketo-piperazine and piperidine derivatives as antiviral agents
AU2008208920A1 (en)	2007-01-24	2008-07-31	Glaxo Group Limited	Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or R(-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an NK1
KR20090035279A (ko) *	2007-10-05	2009-04-09	경희대학교 산학협력단	위장관 손상 예방 및 치료용 조성물
BR112015018847A2 (pt)	2013-02-08	2017-07-18	Gen Mills Inc	produtos alimentícios reduzidos em sódio

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
US4835161A (en) *	1986-02-03	1989-05-30	Janssen Pharmaceutica N.V.	Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
EG17993A (en) *	1986-02-03	1991-08-30	Janssen Pharmaceutica Nv	Anti-histaminic compositions containing n-heterocyclyl-4-piperidinanines
NZ223654A (en) *	1987-03-09	1990-03-27	Janssen Pharmaceutica Nv	1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4943580A (en) *	1987-03-09	1990-07-24	Janssen Pharmaceutica N.V.	Anti-histaminic benzimidazole, imidazopyridine and purine derivatives
EP0721941A4 (en) *	1994-07-15	1996-09-25	Meiji Seika Co	NOVEL COMPOUNDS HAVING AN INHIBITING EFFECT ON PLATELET AGGREGATION
ATE212981T1 (de) *	1994-09-30	2002-02-15	Novartis Erfind Verwalt Gmbh	1-acyl-4-aliphatische aminopiperidin verbindungen
NZ321575A (en) *	1995-10-30	1999-05-28	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives

1996
- 1996-12-13 TW TW085115389A patent/TW429256B/zh not_active IP Right Cessation
- 1996-12-20 HU HU9903987A patent/HU227799B1/hu not_active IP Right Cessation
- 1996-12-20 DE DE69616379T patent/DE69616379T2/de not_active Expired - Lifetime
- 1996-12-20 ES ES96944686T patent/ES2166915T3/es not_active Expired - Lifetime
- 1996-12-20 PT PT96944686T patent/PT869955E/pt unknown
- 1996-12-20 EA EA199800602A patent/EA001247B1/ru not_active IP Right Cessation
- 1996-12-20 PL PL96327440A patent/PL184489B1/pl unknown
- 1996-12-20 SK SK829-98A patent/SK283533B6/sk unknown
- 1996-12-20 DK DK96944686T patent/DK0869955T3/da active
- 1996-12-20 CA CA002238816A patent/CA2238816C/en not_active Expired - Fee Related
- 1996-12-20 BR BR9612326A patent/BR9612326A/pt not_active IP Right Cessation
- 1996-12-20 TR TR1998/01218T patent/TR199801218T2/xx unknown
- 1996-12-20 EP EP96944686A patent/EP0869955B1/en not_active Expired - Lifetime
- 1996-12-20 KR KR10-1998-0704829A patent/KR100439846B1/ko not_active Expired - Fee Related
- 1996-12-20 NZ NZ325839A patent/NZ325839A/xx not_active IP Right Cessation
- 1996-12-20 AU AU13080/97A patent/AU707116B2/en not_active Ceased
- 1996-12-20 SI SI9630394T patent/SI0869955T1/xx unknown
- 1996-12-20 JP JP52402997A patent/JP4177895B2/ja not_active Expired - Fee Related
- 1996-12-20 CZ CZ19981866A patent/CZ294199B6/cs not_active IP Right Cessation
- 1996-12-20 CN CN96199406A patent/CN1117090C/zh not_active Expired - Fee Related
- 1996-12-20 WO PCT/EP1996/005877 patent/WO1997024350A1/en not_active Ceased
- 1996-12-20 AT AT96944686T patent/ATE207484T1/de active
- 1996-12-26 AR ARP960105896A patent/AR005279A1/es active IP Right Grant
- 1996-12-26 MY MYPI96005483A patent/MY121580A/en unknown
1998
- 1998-05-27 NO NO19982406A patent/NO313291B1/no not_active IP Right Cessation
- 1998-06-19 US US09/102,121 patent/US6110939A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2166915T3 (es)	2002-05-01
AU1308097A (en)	1997-07-28
HK1012187A1 (en)	1999-07-30
AR005279A1 (es)	1999-04-28
NZ325839A (en)	1999-05-28
CA2238816A1 (en)	1997-07-10
CA2238816C (en)	2006-03-21
SK82998A3 (en)	1999-01-11
WO1997024350A1 (en)	1997-07-10
JP4177895B2 (ja)	2008-11-05
EA001247B1 (ru)	2000-12-25
EA199800602A1 (ru)	1998-12-24
KR100439846B1 (ko)	2004-10-22
MY121580A (en)	2006-02-28
BR9612326A (pt)	1999-07-13
HUP9903987A2 (hu)	2000-05-28
KR19990076714A (ko)	1999-10-15
CZ186698A3 (cs)	1998-11-11
EP0869955A1 (en)	1998-10-14
EP0869955B1 (en)	2001-10-24
CN1206414A (zh)	1999-01-27
HU227799B1 (hu)	2012-03-28
TR199801218T2 (xx)	1998-12-21
TW429256B (en)	2001-04-11
PL184489B1 (pl)	2002-11-29
HUP9903987A3 (en)	2002-01-28
DK0869955T3 (da)	2002-02-18
NO982406D0 (no)	1998-05-27
ATE207484T1 (de)	2001-11-15
DE69616379T2 (de)	2002-07-04
AU707116B2 (en)	1999-07-01
CN1117090C (zh)	2003-08-06
SI0869955T1 (en)	2002-04-30
DE69616379D1 (de)	2001-11-29
PL327440A1 (en)	1998-12-07
CZ294199B6 (cs)	2004-10-13
NO982406L (no)	1998-08-24
NO313291B1 (no)	2002-09-09
US6110939A (en)	2000-08-29
SK283533B6 (sk)	2003-09-11
JP2000502689A (ja)	2000-03-07

Publication	Publication Date	Title
PT869955E (pt)	2002-04-29	As n-acil-2-substituidas-4-(substituidas com residuos benzimidazolilo ou imidapiridinilo)-piperidinas como antagonistas das taquicininas
BR9506499A (pt)	1997-09-09	Antagonistas biciclicos de fibrinogênio
PT940391E (pt)	2004-12-31	Derivados de quinolina como antagonistas do receptor de taquicinina nk3
PT818454E (pt)	2004-08-31	Derivados de benzimidazole com actividade anti-histaminica
FI905022A7 (fi)	1991-04-14	Fibrinogeenin reseptorin antagonisteja
FI914533A7 (fi)	1992-03-28	Fibrinogeenireseptoriantagonisteja
FI955258L (fi)	1995-11-30	Takykiniiniantagonisteina käyttökelpoisia substituoituja pyrrolidiini-3-yl-alkyyli-piperidiineja
FI946140L (fi)	1995-06-30	Diatsabisyklisiä neurokiniiniantagonisteja
DE69531331D1 (de)	2003-08-28	Phenylpiperidinderivate als neurokinin antagonists
MX9101311A (es)	1992-05-04	Antagonistas receptores de fibrinogeno
FI914535A7 (fi)	1992-03-28	Uusia fibrinogeenireseptoriantagonisteja
FI971685L (fi)	1997-08-13	Takykiniini-antagonisteja
FI960727L (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
FI970523A7 (fi)	1997-02-07	(Atsetidin-1-yylialkyyli)laktaamit takykiniiniantagonisteina
FI941580L (fi)	1994-10-08	Bisyklisiä ansamysiinejä
BR8906451A (pt)	1990-08-28	Composicao de limpeza e alvejamento,aquosa,espessa,estavel
EP0866705A4 (en)	1999-03-03	FIBRINOGENIC RECEPTOR ANTAGONISTS
MX9100717A (es)	1992-04-01	Antagonistas de la bradiquinina
BR9612412A (pt)	1999-07-13	3-Azetidinilalquilpiperidinas ou pirrolidinas como antagonistas taquicinina
DK1021541T3 (da)	2004-08-02	Aminoterminalt trunkeret MCP-2 som chemokinantagonister
KR950703530A (ko)	1995-09-20	5-HT4 길항제(5-HT4 Antagonists)
FI953916L (fi)	1995-08-21	Fibrinogeenireseptoriantagonisteja
PT796848E (pt)	2003-08-29	Antagonistas de bradiquinina heterociclicos substituidos com fluoroalquilo ou fluoroalcoxilo
PT964863E (pt)	2003-10-31	Oxazolidinonas como antagonistas de 5-ht2a
PT923550E (pt)	2003-01-31	Derivados de acilaminoalcenileno-amida como antagonistas de nk1 e nk2