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PT826375E - Utilizacao de lipidos complexos como aditivos estabilizadores para preparacoes farmaceuticas de misturas de enzimas digestivas - Google Patents

Utilizacao de lipidos complexos como aditivos estabilizadores para preparacoes farmaceuticas de misturas de enzimas digestivas

Info

Publication number
PT826375E
PT826375E PT97114330T PT97114330T PT826375E PT 826375 E PT826375 E PT 826375E PT 97114330 T PT97114330 T PT 97114330T PT 97114330 T PT97114330 T PT 97114330T PT 826375 E PT826375 E PT 826375E
Authority
PT
Portugal
Prior art keywords
pharmaceutical preparations
digestive enzyme
stabilizing additives
enzyme mixtures
complex lipids
Prior art date
Application number
PT97114330T
Other languages
English (en)
Inventor
Galle Manfred
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of PT826375E publication Critical patent/PT826375E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
PT97114330T 1996-08-28 1997-08-20 Utilizacao de lipidos complexos como aditivos estabilizadores para preparacoes farmaceuticas de misturas de enzimas digestivas PT826375E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19634752 1996-08-28
DE19724845A DE19724845A1 (de) 1996-08-28 1997-06-12 Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (1)

Publication Number Publication Date
PT826375E true PT826375E (pt) 2005-02-28

Family

ID=26028823

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97114330T PT826375E (pt) 1996-08-28 1997-08-20 Utilizacao de lipidos complexos como aditivos estabilizadores para preparacoes farmaceuticas de misturas de enzimas digestivas

Country Status (21)

Country Link
US (1) US5993806A (pt)
EP (1) EP0826375B1 (pt)
JP (1) JP4593697B2 (pt)
CN (1) CN1199694C (pt)
AR (1) AR008807A1 (pt)
AT (1) ATE284225T1 (pt)
AU (1) AU722151B2 (pt)
BR (1) BR9704554B1 (pt)
CA (1) CA2213151C (pt)
CZ (1) CZ295329B6 (pt)
DE (2) DE19724845A1 (pt)
DK (1) DK0826375T3 (pt)
EE (1) EE04179B1 (pt)
ES (1) ES2235206T3 (pt)
HU (1) HUP9701437A3 (pt)
NO (1) NO973940L (pt)
NZ (1) NZ328616A (pt)
PL (1) PL190140B1 (pt)
PT (1) PT826375E (pt)
SK (1) SK284639B6 (pt)
TR (1) TR199700872A2 (pt)

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US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) * 2000-08-03 2000-09-27 Danisco Solid phase glycerolysis
CN1262308C (zh) * 2000-11-02 2006-07-05 茨利安公司 得自纤毛虫类的酶作为促进消化的药物的应用
US20030099626A1 (en) * 2001-11-20 2003-05-29 Health Education Corporation Nutrient absorption enhancing compositions and methods
JP5032300B2 (ja) 2004-03-22 2012-09-26 アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 界面活性剤を含有している、リパーゼを含有する生成物の、とりわけパンクレアチンの経口医薬組成物
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
WO2007012069A2 (en) * 2005-07-20 2007-01-25 Brophy James S Modification of particle morphology to improve product functionality
AU2006274835B2 (en) * 2005-07-29 2012-05-24 Abbott Laboratories Gmbh Processes for the manufacture of sterilized pancreatin powder
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) * 2006-07-20 2011-07-28 Brophy James S Modification of particle morphology to improve product functionality
US8444967B2 (en) 2010-07-09 2013-05-21 Master Supplements, Inc. Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
BRPI0922653B8 (pt) 2009-01-29 2021-05-25 Nordmark Arzneimittel Gmbh & Co Kg uso de uma lipase bacteriana do tipo pseudomonas em solução aquosa
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
PT2621476E (pt) 2010-10-01 2014-10-16 Aptalis Pharma Ltd Formulações de pancrelipase de baixa potência com revestimento entérico
WO2015020943A2 (en) 2013-08-09 2015-02-12 Aptalis Pharma Ltd. Digestive enzyme composition suitable for enteral administration
AU2014346930A1 (en) * 2013-11-05 2016-01-07 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
CN107073084B (zh) * 2014-11-05 2022-03-25 雅培制药股份有限公司 用于生产具有改善的安全特性的具有脂肪酶活性的组合物和适用于药物用途的组合物的方法
WO2016126970A1 (en) 2015-02-04 2016-08-11 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114862A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956483A (en) * 1968-10-24 1976-05-11 Wilson Pharmaceutical & Chemical Corporation Preparing pancreatin
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) * 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
JPS58148814A (ja) * 1982-03-01 1983-09-05 Fujimoto Seiyaku Kk 消化酵素軟カプセル剤
JPS59169491A (ja) * 1983-03-15 1984-09-25 Duskin Franchise Co Ltd 酵素の安定化法
JPH0229950A (ja) * 1988-07-18 1990-01-31 Nec Corp 光ディスク
JP2679852B2 (ja) * 1989-11-29 1997-11-19 株式会社サム研究所 経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
JP2731035B2 (ja) * 1991-01-24 1998-03-25 マーテック・コーポレイション 微生物油混合物およびその使用
DE4200002A1 (de) * 1992-01-02 1993-07-08 Rudolf V Dipl Chem Dr Noronha Reinigungstablette fuer die zahnprothesen
AU7656894A (en) * 1993-09-15 1995-04-03 Unilever Plc Skin care method and composition
JPH09125096A (ja) * 1995-10-30 1997-05-13 Koei Sangyo:Kk 液状天然油脂洗剤

Also Published As

Publication number Publication date
ES2235206T3 (es) 2005-07-01
JP4593697B2 (ja) 2010-12-08
NO973940D0 (no) 1997-08-27
CA2213151A1 (en) 1998-02-28
TR199700872A3 (tr) 1999-04-21
EE9700249A (et) 1998-04-15
NZ328616A (en) 1999-01-28
HUP9701437A3 (en) 2001-03-28
AU722151B2 (en) 2000-07-20
PL190140B1 (pl) 2005-11-30
CZ218497A3 (cs) 1998-03-18
JPH1077236A (ja) 1998-03-24
HUP9701437A2 (hu) 1998-03-30
AU3530997A (en) 1998-03-05
ATE284225T1 (de) 2004-12-15
DE59712108D1 (de) 2005-01-13
EP0826375A3 (de) 2002-08-14
CN1174743A (zh) 1998-03-04
NO973940L (no) 1998-03-02
PL321825A1 (en) 1998-03-02
CA2213151C (en) 2008-04-01
EP0826375B1 (de) 2004-12-08
CZ295329B6 (cs) 2005-07-13
HK1005224A1 (en) 1998-12-31
DK0826375T3 (da) 2005-01-24
EP0826375A2 (de) 1998-03-04
CN1199694C (zh) 2005-05-04
BR9704554A (pt) 1998-09-15
EE04179B1 (et) 2003-12-15
HU9701437D0 (en) 1997-10-28
SK115997A3 (en) 1998-07-08
AR008807A1 (es) 2000-02-23
SK284639B6 (sk) 2005-08-04
US5993806A (en) 1999-11-30
BR9704554B1 (pt) 2011-12-27
DE19724845A1 (de) 1998-03-05
TR199700872A2 (xx) 1999-04-21

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