BR9704554A - Utilização de lipídios complexos como adições de estabilização para composições farmacêuticas de misturas de enzimas de digestão - Google Patents

Utilização de lipídios complexos como adições de estabilização para composições farmacêuticas de misturas de enzimas de digestão

Info

Publication number: BR9704554A
Authority: BR; Brazil
Prior art keywords: pharmaceutical compositions; enzyme mixtures; complex lipids; digestion enzyme; stabilizing additions
Prior art date: 1996-08-28

Application number

BR9704554A

Other languages

English (en)

Other versions

BR9704554B1 (pt

Inventor

Manfred Galle

Original Assignee

Solvay Pharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-28

Filing date

1997-08-28

Publication date

1998-09-15

1997-08-28 Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh

1998-09-15 Publication of BR9704554A publication Critical patent/BR9704554A/pt

2011-12-27 Publication of BR9704554B1 publication Critical patent/BR9704554B1/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Enzymes And Modification Thereof (AREA)

BRPI9704554-3A 1996-08-28 1997-08-28 utilizaÇço de lipÍdios complexos como adiÇÕes de estabilizaÇço para composiÇÕes farmacÊuticas de misturas de enzimas de digestço, composiÇÕes farmacÊuticas soléveis em Água e kit para preparaÇço de soluÇÕes aquosas. BR9704554B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19634752		1996-08-28
DE19724845A DE19724845A1 (de)	1996-08-28	1997-06-12	Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (2)

Publication Number	Publication Date
BR9704554A true BR9704554A (pt)	1998-09-15
BR9704554B1 BR9704554B1 (pt)	2011-12-27

Family

ID=26028823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9704554-3A BR9704554B1 (pt)	1996-08-28	1997-08-28	utilizaÇço de lipÍdios complexos como adiÇÕes de estabilizaÇço para composiÇÕes farmacÊuticas de misturas de enzimas de digestço, composiÇÕes farmacÊuticas soléveis em Água e kit para preparaÇço de soluÇÕes aquosas.

Country Status (21)

Country	Link
US (1)	US5993806A (pt)
EP (1)	EP0826375B1 (pt)
JP (1)	JP4593697B2 (pt)
CN (1)	CN1199694C (pt)
AR (1)	AR008807A1 (pt)
AT (1)	ATE284225T1 (pt)
AU (1)	AU722151B2 (pt)
BR (1)	BR9704554B1 (pt)
CA (1)	CA2213151C (pt)
CZ (1)	CZ295329B6 (pt)
DE (2)	DE19724845A1 (pt)
DK (1)	DK0826375T3 (pt)
EE (1)	EE04179B1 (pt)
ES (1)	ES2235206T3 (pt)
HU (1)	HUP9701437A3 (pt)
NO (1)	NO973940L (pt)
NZ (1)	NZ328616A (pt)
PL (1)	PL190140B1 (pt)
PT (1)	PT826375E (pt)
SK (1)	SK284639B6 (pt)
TR (1)	TR199700872A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6074689A (en) *	1998-03-10	2000-06-13	Immucell Corporation	Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) *	2000-05-08	2003-01-14	주식회사 바이넥스	선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) *	2000-08-03	2000-09-27	Danisco	Solid phase glycerolysis
CA2427537A1 (en) *	2000-11-02	2002-05-10	Cilian Ag	Use of enzymes obtained from ciliates as medicaments for promoting digestion
US20030099626A1 (en) *	2001-11-20	2003-05-29	Health Education Corporation	Nutrient absorption enhancing compositions and methods
JP5032300B2 (ja) *	2004-03-22	2012-09-26	アボットプロダクツゲゼルシャフトミットベシュレンクテルハフツング	界面活性剤を含有している、リパーゼを含有する生成物の、とりわけパンクレアチンの経口医薬組成物
US7153504B2 (en) *	2004-07-30	2006-12-26	Can Technologies, Inc.	Stabilized pancreas product
EP1919293A4 (en) *	2005-07-20	2010-11-17	James S Brophy	MODIFICATION OF PARTICLE MORPHOLOGY TO ENHANCE THE FUNCTIONALITY OF A PRODUCT
EP2278002B1 (en) *	2005-07-29	2017-07-12	Abbott Laboratories GmbH	Pancreatin with reduced viral content
US9198871B2 (en)	2005-08-15	2015-12-01	Abbott Products Gmbh	Delayed release pancreatin compositions
US11266607B2 (en)	2005-08-15	2022-03-08	AbbVie Pharmaceuticals GmbH	Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en)	2006-05-22	2018-09-11	Abbott Products Gmbh	Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) *	2006-07-20	2011-07-28	Brophy James S	Modification of particle morphology to improve product functionality
US8444967B2 (en)	2010-07-09	2013-05-21	Master Supplements, Inc.	Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) *	2007-11-15	2009-05-21	Solvay Pharmaceuticals Gmbh	Process for separating and determining the viral load in a pancreatin sample
DE102009006594A1 (de)	2009-01-29	2010-08-05	Nordmark Arzneimittel Gmbh & Co. Kg	Pharmazeutisches Präparat
EP2391382B1 (de)	2009-01-29	2014-06-04	Nordmark Arzneimittel GmbH & Co.KG	Pharmazeutisches präparat enthaltend lipase bakteriellen ursprungs
CN108187033A (zh)	2010-10-01	2018-06-22	阿普塔利斯制药有限公司	肠溶包衣的低强度胰脂肪酶制剂
WO2015069677A1 (en) *	2013-11-05	2015-05-14	Aptalis Pharma Ltd.	High potency pancreatin pharmaceutical compositions
EP3030257B1 (en)	2013-08-09	2020-02-19	Allergan Pharmaceuticals International Limited	Digestive enzyme composition suitable for enteral administration
JP2014193909A (ja) *	2014-06-04	2014-10-09	Nordmark Arzneimittel Gmbh & Co Kg	医薬調製物
US20160120964A1 (en) *	2014-11-05	2016-05-05	George Shlieout	Processes for producing compositions with improved safety profile having lipase activity and compositions suitable for pharmaceutical use
US20180028454A1 (en)	2015-02-04	2018-02-01	Abbvie Inc.	Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114857A1 (de)	2015-09-04	2017-03-09	Nordmark Arzneimittel Gmbh & Co. Kg	Getränk, enthaltend eine pharmazeutische Zusammensetzung
DE102015114862A1 (de) *	2015-09-04	2017-03-09	Nordmark Arzneimittel Gmbh & Co. Kg	Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3956483A (en) *	1968-10-24	1976-05-11	Wilson Pharmaceutical & Chemical Corporation	Preparing pancreatin
US3991180A (en) *	1972-03-06	1976-11-09	Rohm And Haas Company	Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) *	1975-03-22	1980-04-24	Kali-Chemie Pharma Gmbh, 3000 Hannover	Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) *	1977-07-20	1981-11-25	Gist Brocades Nv	Enzyme particles
JPS58148814A (ja) *	1982-03-01	1983-09-05	Fujimoto Seiyaku Kk	消化酵素軟カプセル剤
JPS59169491A (ja) *	1983-03-15	1984-09-25	Duskin Franchise Co Ltd	酵素の安定化法
JPH0229950A (ja) *	1988-07-18	1990-01-31	Nec Corp	光ディスク
JP2679852B2 (ja) *	1989-11-29	1997-11-19	株式会社サム研究所	経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) *	1990-03-29	1990-05-30	Skua Investments Ltd	Pharmaceutical formulations
EP1961312A3 (en) *	1991-01-24	2010-03-31	Martek Biosciences Corporation	Microbial oil mixture and uses thereof
DE4200002A1 (de) *	1992-01-02	1993-07-08	Rudolf V Dipl Chem Dr Noronha	Reinigungstablette fuer die zahnprothesen
EP0719133A1 (en) *	1993-09-15	1996-07-03	Unilever Plc	Skin care method and composition
JPH09125096A (ja) *	1995-10-30	1997-05-13	Koei Sangyo:Kk	液状天然油脂洗剤

1997
- 1997-06-12 DE DE19724845A patent/DE19724845A1/de not_active Withdrawn
- 1997-07-09 CZ CZ19972184A patent/CZ295329B6/cs not_active IP Right Cessation
- 1997-08-01 AR ARP970103511A patent/AR008807A1/es unknown
- 1997-08-18 CA CA002213151A patent/CA2213151C/en not_active Expired - Fee Related
- 1997-08-20 AT AT97114330T patent/ATE284225T1/de not_active IP Right Cessation
- 1997-08-20 DE DE1997512108 patent/DE59712108D1/de not_active Expired - Lifetime
- 1997-08-20 ES ES97114330T patent/ES2235206T3/es not_active Expired - Lifetime
- 1997-08-20 PT PT97114330T patent/PT826375E/pt unknown
- 1997-08-20 DK DK97114330T patent/DK0826375T3/da active
- 1997-08-20 EP EP97114330A patent/EP0826375B1/de not_active Expired - Lifetime
- 1997-08-22 SK SK1159-97A patent/SK284639B6/sk unknown
- 1997-08-22 US US08/916,325 patent/US5993806A/en not_active Expired - Lifetime
- 1997-08-25 JP JP22800897A patent/JP4593697B2/ja not_active Expired - Lifetime
- 1997-08-25 HU HU9701437A patent/HUP9701437A3/hu unknown
- 1997-08-27 AU AU35309/97A patent/AU722151B2/en not_active Ceased
- 1997-08-27 NO NO973940A patent/NO973940L/no not_active Application Discontinuation
- 1997-08-27 PL PL97321825A patent/PL190140B1/pl unknown
- 1997-08-27 NZ NZ328616A patent/NZ328616A/xx unknown
- 1997-08-27 CN CNB971177007A patent/CN1199694C/zh not_active Expired - Fee Related
- 1997-08-28 EE EE9700249A patent/EE04179B1/xx not_active IP Right Cessation
- 1997-08-28 BR BRPI9704554-3A patent/BR9704554B1/pt not_active IP Right Cessation
- 1997-08-28 TR TR97/00872A patent/TR199700872A2/xx unknown

Also Published As

Publication number	Publication date
DE59712108D1 (de)	2005-01-13
TR199700872A3 (tr)	1999-04-21
HUP9701437A3 (en)	2001-03-28
NZ328616A (en)	1999-01-28
EP0826375A3 (de)	2002-08-14
DE19724845A1 (de)	1998-03-05
CA2213151C (en)	2008-04-01
AU722151B2 (en)	2000-07-20
NO973940L (no)	1998-03-02
JPH1077236A (ja)	1998-03-24
EE9700249A (et)	1998-04-15
SK115997A3 (en)	1998-07-08
AR008807A1 (es)	2000-02-23
ES2235206T3 (es)	2005-07-01
CN1174743A (zh)	1998-03-04
PL321825A1 (en)	1998-03-02
JP4593697B2 (ja)	2010-12-08
CN1199694C (zh)	2005-05-04
EP0826375B1 (de)	2004-12-08
PT826375E (pt)	2005-02-28
CA2213151A1 (en)	1998-02-28
EP0826375A2 (de)	1998-03-04
US5993806A (en)	1999-11-30
CZ218497A3 (cs)	1998-03-18
DK0826375T3 (da)	2005-01-24
HK1005224A1 (en)	1998-12-31
NO973940D0 (no)	1997-08-27
EE04179B1 (et)	2003-12-15
HU9701437D0 (en)	1997-10-28
HUP9701437A2 (hu)	1998-03-30
CZ295329B6 (cs)	2005-07-13
PL190140B1 (pl)	2005-11-30
BR9704554B1 (pt)	2011-12-27
ATE284225T1 (de)	2004-12-15
TR199700872A2 (xx)	1999-04-21
SK284639B6 (sk)	2005-08-04
AU3530997A (en)	1998-03-05

Publication	Publication Date	Title
BR9704554A (pt)	1998-09-15	Utilização de lipídios complexos como adições de estabilização para composições farmacêuticas de misturas de enzimas de digestão
ID24372A (id)	2000-07-13	SENYAWA-SENYAWA 4-AMINO-TIAZOL-2-IL SEBAGAI PENGHAMBAT-PENGHAMBAT CDKs
PT998272E (pt)	2003-09-30	Composicao farmaceutica para combinacao do descongestionante piperidinoalcanol
ATE235481T1 (de)	2003-04-15	Substituierte benzopyranderivate zur behandlung von entzündungen
PT1066027E (pt)	2003-12-31	Composicao farmaceutica de topiramato
ES2015535B3 (es)	1990-09-01	Composiciones detergentes, componentes de estas, y procedimientos para su preparacion
BR9708735A (pt)	1999-08-03	Derivados de uréia como inibidores da enzina impdh
ID29994A (id)	2001-10-25	Komposisi farmasi untuk melawan ccr5 terdiri dari turunan anilida
HUP0001170A3 (en)	2001-07-30	Pharmaceutical compositions containing benzimidazole-2-carbamate derivatives as active ingredients for the treatment of viral infections and cancer
EP1254899A3 (en)	2003-02-19	Piperazine derivatives and their use as anti-inflammatory agents
FI964583L (fi)	1996-11-15	Tokoferolikoostumuksia biologisesti aktiivisten aineiden antamiseksi
NO20002443L (no)	2000-05-11	FremgangsmÕte for fremstilling av derivater av taxoidklassen
FI20001412L (fi)	2000-06-14	Steroliesterit elintarvikelisäaineina
PT907364E (pt)	2002-12-31	Composicao farmaceutica de libertacao sustida
EP0785772A4 (en)	2005-12-21	LYOPHILISATE OF A LIPID COMPLEX OF WATER-INSOLUBLE CAMTOTHECINS
NO990435D0 (no)	1999-01-29	Fremstilling av estere som overflateaktive midler
ATE497786T1 (de)	2011-02-15	Zusammensetzungen und kits zur erhöhung der abgabe von therapeutischen mitteln an zellen
ID29966A (id)	2001-10-25	Sulfoniloksazolamina-sulfoniloksazolamina sebagai senyawa-senyawa aktif terapi
DE69927585D1 (de)	2006-02-16	Alpha-hydroxy fettsäurenderivate und zubereitungen zur äusserlichen anwendung diese enthaltend
PL332282A1 (en)	1999-08-30	Application of proteins as factors against autoimmunological diseases
PT1097159E (pt)	2003-03-31	Utilizacao de derivados de acidos fosfinicos e fosfonicos como medicamentos
MX9100886A (es)	1992-05-04	Activador de plasminogeno hibrido,procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
ID24694A (id)	2000-08-03	Pemakaian bentuk zat-zat sebagai katalis untuk pembuatan kaprolaktam
DE59813114D1 (de)	2006-03-02	BK-RiV-Präparate zur Behandlung von proliferativen Zellerkrangungen
ZA981729B (en)	1998-08-28	Use of pivagabin to prepare pharmaceutical compositions

Legal Events

Date	Code	Title	Description
2002-06-18	FB34	Technical and formal requirements: requirement - article 34 of industrial property law
2007-04-17	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2007-12-18	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2010-03-23	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2011-05-31	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2011-12-27	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/12/2011, OBSERVADAS AS CONDICOES LEGAIS.
2013-01-08	B25D	Requested change of name of applicant approved
2017-06-27	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
2017-10-24	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)