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PT2240578T - Furina recombinante substancialmente isenta de proteínas animais e métodos para a sua produção - Google Patents

Furina recombinante substancialmente isenta de proteínas animais e métodos para a sua produção

Info

Publication number
PT2240578T
PT2240578T PT08869658T PT08869658T PT2240578T PT 2240578 T PT2240578 T PT 2240578T PT 08869658 T PT08869658 T PT 08869658T PT 08869658 T PT08869658 T PT 08869658T PT 2240578 T PT2240578 T PT 2240578T
Authority
PT
Portugal
Prior art keywords
methods
animal protein
producing same
free recombinant
recombinant furin
Prior art date
Application number
PT08869658T
Other languages
English (en)
Inventor
Plaimauer Barbara
Von Fircks Simone
Grillberger Leopold
Hasslacher Meinhard
Geyer Roland
Mitterer Artur
Reiter Manfred
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40524590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2240578(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Publication of PT2240578T publication Critical patent/PT2240578T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6454—Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT08869658T 2007-12-31 2008-12-19 Furina recombinante substancialmente isenta de proteínas animais e métodos para a sua produção PT2240578T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1815207P 2007-12-31 2007-12-31

Publications (1)

Publication Number Publication Date
PT2240578T true PT2240578T (pt) 2019-06-19

Family

ID=40524590

Family Applications (1)

Application Number Title Priority Date Filing Date
PT08869658T PT2240578T (pt) 2007-12-31 2008-12-19 Furina recombinante substancialmente isenta de proteínas animais e métodos para a sua produção

Country Status (18)

Country Link
US (2) US20090181423A1 (pt)
EP (2) EP3521422B1 (pt)
JP (2) JP5806465B2 (pt)
KR (1) KR101618144B1 (pt)
CN (2) CN110066782B (pt)
AR (2) AR069892A1 (pt)
AU (1) AU2008346817B2 (pt)
BR (1) BRPI0821467B8 (pt)
CA (1) CA2710260C (pt)
DK (1) DK2240578T3 (pt)
ES (2) ES2735173T3 (pt)
HU (1) HUE043863T2 (pt)
MX (1) MX2010007344A (pt)
NZ (1) NZ586411A (pt)
PL (2) PL2240578T3 (pt)
PT (1) PT2240578T (pt)
SG (2) SG192471A1 (pt)
WO (1) WO2009088713A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2147097A2 (en) * 2007-05-22 2010-01-27 Baxter Int PREPARATIVE PURIFICATION METHOD FOR HUMAN FURINE
BRPI0821467B8 (pt) 2007-12-31 2021-05-25 Baxalta GmbH composição de furina recombinante, método para produzir a composição de furina recombinante, e, método para produzir uma proteína madura utilizando a composição de furina recombinante
US8241623B1 (en) 2009-02-09 2012-08-14 David Bermudes Protease sensitivity expression system
PT3064508T (pt) 2010-07-08 2019-12-05 Baxalta Inc Método de produção de fvw recombinante de elevado peso molecular na cultura de células
WO2012122611A1 (en) * 2011-03-11 2012-09-20 Universidade De São Paulo - Usp Method for the production of recombinant human factor viii
WO2012167271A1 (en) 2011-06-02 2012-12-06 Baxter International Inc. Formulations of recombinant furin
TWI666319B (zh) * 2014-08-12 2019-07-21 美商巴克斯歐塔公司 在分泌ｆｕｒｉｎ之哺乳動物表現系統中生產經完全加工且具功能性之因子Ｘ
IL253071B2 (en) 2014-12-22 2024-04-01 Genzyme Corp Methods for growing mammalian cells
US11299533B2 (en) 2017-06-23 2022-04-12 Takeda Pharmaceutical Company Limited Purification of factor VIII subspecies

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1815207A (en) 1929-01-18 1931-07-21 John H Moffat Vehicle parking and locking device
NL9000917A (nl) 1989-10-25 1991-05-16 Holland Biotechnology Farmaceutisch preparaat met endoproteolytische activiteit; werkwijze voor endoproteolytische processing van (precursor) eiwitten en voor de (micro) biologische bereiding van eiwitten.
ES2109336T3 (es) 1990-11-26 1998-01-16 Genetics Inst Expresion de pace en celulas huesped y metodos de utilizacion de la misma.
US5604201A (en) * 1993-01-08 1997-02-18 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Methods and reagents for inhibiting furin endoprotease
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
EP1983044B1 (en) 1996-10-10 2016-08-10 Life Technologies Corporation Animal cell culture media comprising plant-derived nutrients
AT407750B (de) 1999-02-19 2001-05-25 Immuno Ag Verfahren zur herstellung einer vwf-präparation
US6596526B1 (en) * 2000-06-09 2003-07-22 Baxter Aktiengesellschaft Furin polypeptides with improved characteristics
SE0103084D0 (sv) * 2001-09-14 2001-09-14 Amersham Pharm Biotech Ab Generation of ion exchange media
US20030091976A1 (en) 2001-11-14 2003-05-15 Ciphergen Biosystems, Inc. Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
PT2287288E (pt) * 2002-07-09 2012-12-10 Baxter Int Meio isento de proteína animal para cultura de células
NZ548126A (en) * 2004-02-27 2009-10-30 Ge Healthcare Bio Sciences Ab A process for the purification of antibodies involving addition of a second resin
WO2007077217A2 (en) * 2006-01-04 2007-07-12 Baxter International Inc. Oligopeptide-free cell culture media
EP2147097A2 (en) * 2007-05-22 2010-01-27 Baxter Int PREPARATIVE PURIFICATION METHOD FOR HUMAN FURINE
BRPI0821467B8 (pt) 2007-12-31 2021-05-25 Baxalta GmbH composição de furina recombinante, método para produzir a composição de furina recombinante, e, método para produzir uma proteína madura utilizando a composição de furina recombinante
US9718255B2 (en) 2011-11-03 2017-08-01 Barson Composites Corporation Corrosion-resistant diffusion coatings

Also Published As

Publication number Publication date
PL3521422T3 (pl) 2021-12-20
ES2735173T3 (es) 2019-12-16
EP2240578B1 (en) 2019-03-20
US20090181423A1 (en) 2009-07-16
CN101910401A (zh) 2010-12-08
AU2008346817A1 (en) 2009-07-16
DK2240578T3 (da) 2019-06-17
EP2240578A1 (en) 2010-10-20
SG10201805749QA (en) 2018-08-30
CN110066782B (zh) 2024-04-16
CA2710260C (en) 2023-07-11
BRPI0821467B1 (pt) 2019-10-15
JP2015154790A (ja) 2015-08-27
CA2710260A1 (en) 2009-07-16
NZ586411A (en) 2012-06-29
JP5806465B2 (ja) 2015-11-10
US20110076719A1 (en) 2011-03-31
AR113492A2 (es) 2020-05-06
BRPI0821467A2 (pt) 2014-10-14
AU2008346817B2 (en) 2014-07-24
JP2011507550A (ja) 2011-03-10
MX2010007344A (es) 2010-11-09
SG192471A1 (en) 2013-08-30
HUE043863T2 (hu) 2019-09-30
KR101618144B1 (ko) 2016-05-17
WO2009088713A1 (en) 2009-07-16
PL2240578T3 (pl) 2019-09-30
CN110066782A (zh) 2019-07-30
EP3521422B1 (en) 2021-10-06
EP3521422A1 (en) 2019-08-07
KR20100114057A (ko) 2010-10-22
BRPI0821467B8 (pt) 2021-05-25
US9127264B2 (en) 2015-09-08
AR069892A1 (es) 2010-02-24
ES2897561T3 (es) 2022-03-01

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