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PT1747008E - Extrato em bruto de andrographis paniculata - Google Patents

Extrato em bruto de andrographis paniculata Download PDF

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Publication number
PT1747008E
PT1747008E PT05742174T PT05742174T PT1747008E PT 1747008 E PT1747008 E PT 1747008E PT 05742174 T PT05742174 T PT 05742174T PT 05742174 T PT05742174 T PT 05742174T PT 1747008 E PT1747008 E PT 1747008E
Authority
PT
Portugal
Prior art keywords
crude extracts
andrographis paniculata
paniculata
andrographis
crude
Prior art date
Application number
PT05742174T
Other languages
English (en)
Inventor
Xiaoqiang Yan
Tao Wang
Zhiming Ma
Weihan Zhang
Jifen Duan
Yu Cai
Original Assignee
Nutrition Science Partners Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrition Science Partners Ltd filed Critical Nutrition Science Partners Ltd
Publication of PT1747008E publication Critical patent/PT1747008E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
PT05742174T 2004-04-28 2005-04-26 Extrato em bruto de andrographis paniculata PT1747008E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56647704P 2004-04-28 2004-04-28

Publications (1)

Publication Number Publication Date
PT1747008E true PT1747008E (pt) 2015-03-31

Family

ID=35242143

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05742174T PT1747008E (pt) 2004-04-28 2005-04-26 Extrato em bruto de andrographis paniculata

Country Status (14)

Country Link
US (3) US7341748B2 (pt)
EP (1) EP1747008B1 (pt)
JP (1) JP5221128B2 (pt)
KR (3) KR101531116B1 (pt)
AU (1) AU2005237550B2 (pt)
CA (1) CA2564637C (pt)
DK (1) DK1747008T3 (pt)
ES (1) ES2534594T3 (pt)
HU (1) HUE025117T2 (pt)
PL (1) PL1747008T3 (pt)
PT (1) PT1747008E (pt)
RU (1) RU2383353C2 (pt)
TW (1) TWI373340B (pt)
WO (1) WO2005104722A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625945B2 (en) * 2004-03-11 2009-12-01 Hutchison MediPharma Enterprises Ltd. Andrographolide and analogues as inhibitors of TNFα and IL-1β expression
CA2564637C (en) 2004-04-28 2013-09-10 Hutchison Medipharma Enterprises Limited Crude extracts from andrographis paniculata
JP2007176934A (ja) * 2005-11-30 2007-07-12 Kose Corp 血小板活性化因子アセチルヒドロラーゼ機能調整剤
US20070202164A1 (en) * 2006-02-28 2007-08-30 Hutchison Medipharma Enterprises Limited Andrographis Extract Formulations
EP1882473A1 (en) * 2006-07-28 2008-01-30 Indena S.P.A. Use of anthocyanosides to prepare formulations for the treatment of mucositis induced by antitumoral drugs
US20090117209A1 (en) * 2007-11-02 2009-05-07 Hutchison Medipharma Enterprises Limited Andrographis paniculata extract
CN102481284A (zh) * 2009-03-24 2012-05-30 新加坡国立大学 穿心莲内酯化合物用于治疗炎症和气道病症的用途
MD480Z (ro) * 2011-07-07 2012-09-30 Elvira Andon Metoda de tratament al colitei ulceroase nespecifice acute
CN102702147B (zh) * 2012-06-18 2016-06-08 辽宁利锋科技开发有限公司 穿心莲内酯类似物及其治疗的应用
CN103145661B (zh) * 2013-03-25 2014-06-18 成都天台山制药有限公司 穿心莲内酯的新晶型
CN103145660B (zh) * 2013-03-25 2014-09-17 成都天台山制药有限公司 穿心莲内酯及其制备方法
CN103223028A (zh) * 2013-03-27 2013-07-31 张宗升 中药提取物
CN103766901A (zh) * 2014-01-08 2014-05-07 浙江大学 一种穿心莲丙素在制备减肥食品或药品中的应用
JP6386761B2 (ja) * 2014-03-19 2018-09-05 花王株式会社 インボルクリン発現抑制剤
MY176459A (en) * 2016-05-23 2020-08-10 Univ Putra Malaysia Extract of andrographis paniculata for cognitive enhancement
WO2018081959A1 (en) 2016-11-02 2018-05-11 Nutrition Science Partners Limited Extracts of andrographis paniculata, methods for preparation and use thereof
CN107349253A (zh) * 2017-06-23 2017-11-17 苏州凌科特新材料有限公司 无刺激医用消毒液及其制备方法
WO2022058422A1 (en) * 2020-09-17 2022-03-24 Dsm Ip Assets B.V. Use of andrographis paniculata extract to protect against air pollution related diseases
WO2024092327A1 (pt) * 2022-10-31 2024-05-10 Mey, Angelica Machado Composição para obtenção de bioativo natural para terapias oncológicas
KR102713383B1 (ko) * 2023-09-04 2024-10-04 김현주 인간을 제외한 동물의 면역력 증진을 위한 조성물

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1012941B (zh) 1989-07-29 1991-06-26 郭如明 穿心莲碱水法新工艺
WO1996017605A1 (en) * 1994-12-06 1996-06-13 Paracelsian, Inc. Use of andrographolide compounds to treat or prevent pathogenicity of diseases
US20030059471A1 (en) 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
ES2299241T3 (es) * 1998-03-17 2008-05-16 Chugai Seiyaku Kabushiki Kaisha Preventivos o remedios para enfermedades intestinales inflamatorias que contienen anticuerpos antagonistas del receptor il-6.
JP2000034233A (ja) * 1998-07-15 2000-02-02 Sumitomo Forestry Co Ltd 一酸化窒素産生抑制剤
JP2001058969A (ja) 1999-08-20 2001-03-06 Nettairin Saisei Gijutsu Kenkyu Kumiai 一酸化窒素産生抑制剤
EA008612B1 (ru) 2000-07-28 2007-06-29 Иммуфарм Апс Способ лечения обычной простуды, аллергического ринита и инфекций дыхательных путей
US6629835B2 (en) 2000-08-01 2003-10-07 Metaproteomics, Llc Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2
US6358526B1 (en) 2000-08-16 2002-03-19 Rexall Sundown Method of making tablets and tablet compositions produced therefrom
US7270835B2 (en) 2001-06-20 2007-09-18 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
US20030101076A1 (en) 2001-10-02 2003-05-29 Zaleski John R. System for supporting clinical decision making through the modeling of acquired patient medical information
US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
JP2003171301A (ja) 2001-11-09 2003-06-20 Mahidol Univ 歯周炎治療における補助剤としてのカルメグゲル
JP4669920B2 (ja) 2002-08-21 2011-04-13 沖縄県 血糖上昇抑制且つ血圧上昇抑制作用を有する機能性素材
CN1488376A (zh) 2003-05-09 2004-04-14 江西诚志信丰药业有限责任公司 一种治疗肠道疾病及鼻窦炎的药物胶囊及其制备方法
CN1626076B (zh) 2003-12-11 2010-10-06 天津天士力制药股份有限公司 一种穿心莲内酯滴丸及其制备方法
KR101065608B1 (ko) 2003-12-29 2011-09-19 주식회사 엘지생활건강 안드로그라폴라이드 또는 안드로그라폴라이드를유효성분으로 함유하는 천심련 추출물을 포함하는가려움증 억제 또는 완화 조성물
US7625945B2 (en) 2004-03-11 2009-12-01 Hutchison MediPharma Enterprises Ltd. Andrographolide and analogues as inhibitors of TNFα and IL-1β expression
CA2564637C (en) 2004-04-28 2013-09-10 Hutchison Medipharma Enterprises Limited Crude extracts from andrographis paniculata
US20070218114A1 (en) 2004-06-12 2007-09-20 Passionfor Life Healthcare Limited Soluble Strip for Oral or Topical Administration
CN1628764A (zh) 2004-08-19 2005-06-22 贵阳云岩西创药物科技开发有限公司 穿心莲制剂及其制备方法
US20070202164A1 (en) 2006-02-28 2007-08-30 Hutchison Medipharma Enterprises Limited Andrographis Extract Formulations
US20090117209A1 (en) 2007-11-02 2009-05-07 Hutchison Medipharma Enterprises Limited Andrographis paniculata extract

Also Published As

Publication number Publication date
ES2534594T3 (es) 2015-04-24
WO2005104722A2 (en) 2005-11-10
JP2007535542A (ja) 2007-12-06
KR20130012979A (ko) 2013-02-05
KR101534844B1 (ko) 2015-07-07
EP1747008A2 (en) 2007-01-31
USRE43423E1 (en) 2012-05-29
PL1747008T3 (pl) 2015-10-30
KR101531116B1 (ko) 2015-06-23
JP5221128B2 (ja) 2013-06-26
EP1747008B1 (en) 2015-01-14
RU2006141834A (ru) 2008-06-10
CA2564637C (en) 2013-09-10
USRE42718E1 (en) 2011-09-20
CA2564637A1 (en) 2005-11-10
KR20150047645A (ko) 2015-05-04
TW200538144A (en) 2005-12-01
EP1747008A4 (en) 2009-04-22
TWI373340B (en) 2012-10-01
KR101536892B1 (ko) 2015-07-14
KR20070033982A (ko) 2007-03-27
AU2005237550A1 (en) 2005-11-10
US7341748B2 (en) 2008-03-11
HUE025117T2 (en) 2016-02-29
US20060246156A1 (en) 2006-11-02
WO2005104722A3 (en) 2006-03-02
RU2383353C2 (ru) 2010-03-10
DK1747008T3 (en) 2015-03-30
AU2005237550B2 (en) 2010-09-23

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