PL2121687T3 - Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej - Google Patents
Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowejInfo
- Publication number
- PL2121687T3 PL2121687T3 PL07848681T PL07848681T PL2121687T3 PL 2121687 T3 PL2121687 T3 PL 2121687T3 PL 07848681 T PL07848681 T PL 07848681T PL 07848681 T PL07848681 T PL 07848681T PL 2121687 T3 PL2121687 T3 PL 2121687T3
- Authority
- PL
- Poland
- Prior art keywords
- tyrosine kinase
- kinase inhibitors
- protein tyrosine
- amine derivatives
- tricyclic amine
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 239000005483 tyrosine kinase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87153806P | 2006-12-22 | 2006-12-22 | |
| GB0625827A GB0625827D0 (en) | 2006-12-22 | 2006-12-22 | New compounds |
| US97958207P | 2007-10-12 | 2007-10-12 | |
| GB0719998A GB0719998D0 (en) | 2007-10-12 | 2007-10-12 | New compounds |
| PCT/GB2007/004960 WO2008078100A2 (en) | 2006-12-22 | 2007-12-21 | Tricyclic amine derivatives as protein tyrosine kinase inhibitors |
| EP07848681.8A EP2121687B1 (en) | 2006-12-22 | 2007-12-21 | Tricyclic amine derivatives as protein tyrosine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2121687T3 true PL2121687T3 (pl) | 2016-03-31 |
Family
ID=39322759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07848681T PL2121687T3 (pl) | 2006-12-22 | 2007-12-21 | Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8513276B2 (pl) |
| EP (1) | EP2121687B1 (pl) |
| JP (1) | JP5442449B2 (pl) |
| CN (1) | CN101679409B (pl) |
| AU (1) | AU2007337895C1 (pl) |
| CA (1) | CA2672213C (pl) |
| CY (1) | CY1117319T1 (pl) |
| HR (1) | HRP20151398T1 (pl) |
| MX (1) | MX2009006704A (pl) |
| NO (1) | NO342865B1 (pl) |
| PL (1) | PL2121687T3 (pl) |
| WO (1) | WO2008078100A2 (pl) |
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| JP5442448B2 (ja) * | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | Ｆｇｆｒインヒビターとしての二環式ヘテロ環式化合物 |
| PL2121687T3 (pl) | 2006-12-22 | 2016-03-31 | Astex Therapeutics Ltd | Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| ES2365966T3 (es) | 2007-09-14 | 2011-10-14 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-disustituidas. |
| WO2009033703A1 (en) | 2007-09-14 | 2009-03-19 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones |
| BRPI0816767B8 (pt) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos |
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| GB0906472D0 (en) * | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
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-
2007
- 2007-12-21 PL PL07848681T patent/PL2121687T3/pl unknown
- 2007-12-21 US US12/520,333 patent/US8513276B2/en not_active Expired - Fee Related
- 2007-12-21 WO PCT/GB2007/004960 patent/WO2008078100A2/en not_active Ceased
- 2007-12-21 MX MX2009006704A patent/MX2009006704A/es active IP Right Grant
- 2007-12-21 HR HRP20151398TT patent/HRP20151398T1/hr unknown
- 2007-12-21 EP EP07848681.8A patent/EP2121687B1/en active Active
- 2007-12-21 JP JP2009542227A patent/JP5442449B2/ja not_active Expired - Fee Related
- 2007-12-21 AU AU2007337895A patent/AU2007337895C1/en not_active Ceased
- 2007-12-21 CA CA2672213A patent/CA2672213C/en active Active
- 2007-12-21 CN CN200780047742.8A patent/CN101679409B/zh not_active Expired - Fee Related
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2009
- 2009-07-13 NO NO20092658A patent/NO342865B1/no unknown
-
2016
- 2016-01-11 CY CY20161100015T patent/CY1117319T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO342865B1 (no) | 2018-08-20 |
| AU2007337895C1 (en) | 2014-07-31 |
| CA2672213C (en) | 2016-02-16 |
| US8513276B2 (en) | 2013-08-20 |
| JP5442449B2 (ja) | 2014-03-12 |
| AU2007337895B2 (en) | 2014-01-30 |
| CA2672213A1 (en) | 2008-07-03 |
| NO20092658L (no) | 2009-09-17 |
| EP2121687B1 (en) | 2015-10-14 |
| CN101679409B (zh) | 2014-11-26 |
| CN101679409A (zh) | 2010-03-24 |
| WO2008078100A3 (en) | 2008-11-13 |
| AU2007337895A1 (en) | 2008-07-03 |
| MX2009006704A (es) | 2009-06-30 |
| WO2008078100A2 (en) | 2008-07-03 |
| CY1117319T1 (el) | 2017-04-26 |
| JP2010513448A (ja) | 2010-04-30 |
| US20100093718A1 (en) | 2010-04-15 |
| EP2121687A2 (en) | 2009-11-25 |
| HRP20151398T1 (hr) | 2016-02-12 |
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