PL1676848T3 - Formy polimorficzne ryfaksyminy jako antybiotyki - Google Patents
Formy polimorficzne ryfaksyminy jako antybiotykiInfo
- Publication number
- PL1676848T3 PL1676848T3 PL06004220T PL06004220T PL1676848T3 PL 1676848 T3 PL1676848 T3 PL 1676848T3 PL 06004220 T PL06004220 T PL 06004220T PL 06004220 T PL06004220 T PL 06004220T PL 1676848 T3 PL1676848 T3 PL 1676848T3
- Authority
- PL
- Poland
- Prior art keywords
- rifaximin
- antibiotics
- polymorphous forms
- polymorphous
- forms
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 title 1
- 229960003040 rifaximin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1236—Cooking devices induction cooking plates or the like and devices to be used in combination with them adapted to induce current in a coil to supply power to a device and electrical heating devices powered in this way
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1245—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements
- H05B6/1263—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements using coil cooling arrangements
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Electromagnetism (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT002144A ITMI20032144A1 (it) | 2003-11-07 | 2003-11-07 | Forme polimorfe di rifaximina, processi per ottenerle e |
| EP04005541A EP1557421B1 (en) | 2003-11-07 | 2004-03-09 | Polymorphous form of rifaximin as antibiotic |
| EP06004220A EP1676848B1 (en) | 2003-11-07 | 2004-03-09 | Polymorphous forms of rifaximin as antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1676848T3 true PL1676848T3 (pl) | 2009-07-31 |
Family
ID=33187382
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06004220T PL1676848T3 (pl) | 2003-11-07 | 2004-03-09 | Formy polimorficzne ryfaksyminy jako antybiotyki |
| PL04005541T PL1557421T3 (pl) | 2003-11-07 | 2004-03-09 | Formy polimorficzne ryfaksyminy jako antybiotyki |
| PL06004219T PL1676847T3 (pl) | 2003-11-07 | 2004-03-09 | Formy polimorficzne ryfaksyminy jako antybiotyki |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04005541T PL1557421T3 (pl) | 2003-11-07 | 2004-03-09 | Formy polimorficzne ryfaksyminy jako antybiotyki |
| PL06004219T PL1676847T3 (pl) | 2003-11-07 | 2004-03-09 | Formy polimorficzne ryfaksyminy jako antybiotyki |
Country Status (37)
| Country | Link |
|---|---|
| US (5) | US7045620B2 (pl) |
| EP (6) | EP1676848B1 (pl) |
| JP (5) | JP2005139161A (pl) |
| KR (4) | KR20050043589A (pl) |
| CN (4) | CN1613858A (pl) |
| AR (3) | AR043547A1 (pl) |
| AT (3) | ATE361927T1 (pl) |
| AU (2) | AU2004200964A1 (pl) |
| BR (2) | BRPI0402382A (pl) |
| CA (2) | CA2460384A1 (pl) |
| CL (1) | CL2004000498A1 (pl) |
| CO (1) | CO5560083A1 (pl) |
| CY (3) | CY1108017T1 (pl) |
| DE (4) | DE602004006367C5 (pl) |
| DK (3) | DK1676847T3 (pl) |
| ES (3) | ES2244364T3 (pl) |
| HR (2) | HRP20040265A2 (pl) |
| IL (2) | IL160798A0 (pl) |
| IT (1) | ITMI20032144A1 (pl) |
| JO (1) | JO2470B1 (pl) |
| MA (1) | MA27069A1 (pl) |
| MD (1) | MD3653G8 (pl) |
| ME (1) | ME00424B (pl) |
| MX (2) | MXPA04002353A (pl) |
| NO (1) | NO334950B1 (pl) |
| NZ (1) | NZ531622A (pl) |
| PL (3) | PL1676848T3 (pl) |
| PT (3) | PT1557421E (pl) |
| RS (4) | RS54568B1 (pl) |
| RU (1) | RU2270200C2 (pl) |
| SI (3) | SI1676848T1 (pl) |
| TN (2) | TNSN04044A1 (pl) |
| TW (1) | TWI285107B (pl) |
| UA (1) | UA86384C2 (pl) |
| WO (1) | WO2005044823A2 (pl) |
| YU (1) | YU24804A (pl) |
| ZA (1) | ZA200401948B (pl) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
| US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
| US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
| ITMI20032144A1 (it) * | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
| US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
| PL1698630T3 (pl) | 2005-03-03 | 2014-12-31 | Alfasigma Spa | Nowe postacie polimorficzne rifaksyminy,sposoby ich wytwarzania i ich zastosowanie w preparatach leczniczych |
| ITBO20050123A1 (it) * | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
| EP2054066B1 (en) | 2006-08-02 | 2015-04-15 | Salix Pharmaceuticals, Inc. | Methods for treatment of radiation enteritis |
| ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
| NZ575550A (en) * | 2006-09-22 | 2011-12-22 | Cipla Ltd | Rifaximin |
| US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
| US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
| ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
| US8383151B2 (en) * | 2007-07-06 | 2013-02-26 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| ES2905795T3 (es) * | 2007-07-06 | 2022-04-12 | Lupin Ltd | Composiciones farmacéuticas de rifaximina |
| AU2016203925B2 (en) * | 2007-07-06 | 2016-10-20 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| JP5706693B2 (ja) | 2008-02-25 | 2015-04-22 | サリックス ファーマシューティカルズ リミテッド | リファキシミンの型およびその使用 |
| US11779571B2 (en) * | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
| CN101959412A (zh) * | 2008-02-26 | 2011-01-26 | 萨利克斯药品有限公司 | 治疗肠病的方法 |
| US20090324736A1 (en) | 2008-05-07 | 2009-12-31 | Salix Pharmaceuticals, Ltd. | Methods of treating bowel diseases by administering a bowel cleanser and an antibiotic |
| JP5567484B2 (ja) | 2008-09-26 | 2014-08-06 | あすか製薬株式会社 | 機能性消化管障害の予防及び/又は治療剤 |
| US7928115B2 (en) * | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| US12285414B2 (en) | 2008-10-02 | 2025-04-29 | Salix Pharmaceuticals, Inc. | Methods of treating hepatic encephalopathy |
| US20110035232A1 (en) | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| LT2350096T (lt) | 2008-10-02 | 2020-03-10 | Salix Pharmaceuticals, Ltd. | Hepatinės encefalopatijos gydymo būdai |
| US20100317681A1 (en) * | 2009-06-15 | 2010-12-16 | Salix Pharmaceuticals, Ltd. | Modulation of systemic exposure to rifaximin |
| CA2745980C (en) | 2008-12-10 | 2017-10-31 | Cipla Limited | Rifaximin complexes |
| IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
| KR20120025578A (ko) * | 2009-06-02 | 2012-03-15 | 샐릭스 파마슈티컬스 리미티드 | 간성 뇌병증의 치료방법 |
| BR112012005627A2 (pt) * | 2009-09-13 | 2017-02-21 | Salix Pharmaceuticals Ltd | "uso de rifaximina para preparação de um medicamento para tratar síndrome do intestino irritável (ibs)" |
| CN102665693A (zh) * | 2009-10-27 | 2012-09-12 | 鲁平有限公司 | 利福昔明固体分散体 |
| WO2011061748A1 (en) * | 2009-11-19 | 2011-05-26 | Strides Arcolab Limited | Rifaximin premix |
| WO2011061519A2 (en) | 2009-11-23 | 2011-05-26 | Cipla Limited | Topical foam composition |
| US8952159B2 (en) | 2009-12-28 | 2015-02-10 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
| CA2789929C (en) | 2010-02-18 | 2019-11-26 | Salix Pharmaceuticals, Ltd. | Methods for treating infection |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| US8513275B2 (en) * | 2010-06-03 | 2013-08-20 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| EP2582707A4 (en) * | 2010-06-16 | 2014-01-08 | Apotex Pharmachem Inc | POLYMORPHIC FORMS OF RIFAXIMINE |
| DK2593463T3 (da) | 2010-07-12 | 2020-08-10 | Salix Pharmaceuticals Inc | Formuleringer af rifaximin og anvendelser deraf |
| US8759513B2 (en) | 2010-09-13 | 2014-06-24 | Sequent Scientific Limited | Polymorphic form of rifaximin and process for its preparation |
| IT1403847B1 (it) * | 2010-09-22 | 2013-11-08 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina e loro uso. |
| WO2012060675A1 (es) * | 2010-11-05 | 2012-05-10 | Interquim, S.A. De C.V. | Proceso para la preparación de rifaximina amorfa |
| WO2012076832A1 (en) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
| CN103827122B (zh) * | 2011-02-11 | 2016-08-31 | 萨利克斯药品有限公司 | 利福昔明的形式及其用途 |
| CA2834829A1 (en) | 2011-05-02 | 2012-11-08 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
| ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
| WO2012155981A1 (en) | 2011-05-19 | 2012-11-22 | Friulchem Spa | New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby |
| ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
| ES2986825T3 (es) | 2011-11-02 | 2024-11-12 | Salix Pharmaceuticals Inc | Rifaximina para la repetición de tratamiento del síndrome del intestino irritable con predominio de diarrea |
| JP2013184902A (ja) * | 2012-03-06 | 2013-09-19 | Aska Pharmaceutical Co Ltd | リファキシミン含有結晶 |
| CA2876737A1 (en) | 2012-06-13 | 2013-12-19 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
| ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
| US9849090B2 (en) | 2012-12-12 | 2017-12-26 | Sun Pharmaceutical Industries Limited | Pharmaceutical compositions of rifaximin |
| US20160047819A1 (en) | 2013-03-15 | 2016-02-18 | Alfa Wassermann S.P.A. | Method for diagnosing vaginal infections |
| US20160038468A1 (en) | 2013-03-15 | 2016-02-11 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
| PL2983647T3 (pl) | 2013-04-12 | 2021-01-25 | Alfasigma S.P.A. | Podawanie nlpz oraz związane z tym składniki, sposoby i układy |
| US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
| ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
| EP3134415A4 (en) * | 2014-04-19 | 2017-10-25 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
| JP6693946B2 (ja) | 2014-05-04 | 2020-05-13 | サリックス ファーマスーティカルズ,インコーポレーテッド | Ibs微生物叢及びその使用 |
| RS60576B1 (sr) | 2014-05-12 | 2020-08-31 | Alfasigma Spa | Priprema i upotreba tau kristalnog oblika rifaksimina solvatisanog sa degme |
| WO2016003536A1 (en) * | 2014-06-30 | 2016-01-07 | Salix Pharmaceuticals, Inc. | Methods for retreating irritable bowel syndrome (ibs) |
| CN104083324B (zh) * | 2014-07-10 | 2017-05-10 | 青岛动保国家工程技术研究中心有限公司 | 一种利福昔明的兽用悬乳剂及其制备方法和应用 |
| EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
| CN104274391B (zh) * | 2014-10-08 | 2017-02-01 | 哈尔滨坤盟医药科技有限公司 | 一种含利福昔明的药物制剂 |
| WO2017021975A1 (en) * | 2015-08-06 | 2017-02-09 | Msn Laboratories Private Limited | Process for the preparation of crystalline forms of rifaximin |
| ES2893869T3 (es) | 2016-03-24 | 2022-02-10 | Sandoz Ag | Composición farmacéutica que contiene rifaximina alfa y delta |
| US10842782B2 (en) | 2016-03-24 | 2020-11-24 | Sandoz Ag | Storage stable composition comprising rifaximin alpha |
| US9988398B2 (en) * | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
| KR102494049B1 (ko) | 2016-09-30 | 2023-01-31 | 샐릭스 파마슈티컬스 인코포레이티드 | 리팍시민의 고체 분산물 형태 |
| CN106632396B (zh) * | 2017-01-06 | 2019-01-11 | 成都樵枫科技发展有限公司 | γ晶型利福昔明的制备方法和用途 |
| MX2018010065A (es) | 2017-04-26 | 2019-02-07 | Sandoz Ag | Forma de dosificacion oral que comprende rifaximina en forma beta. |
| DK3645539T3 (da) | 2017-06-26 | 2021-05-10 | Biofer Spa | Pyrido-imidazo-rifamycin-derivater som antibakterielt middel |
| WO2020128583A1 (en) * | 2018-12-19 | 2020-06-25 | Friulchem S.P.A. | Process for the manufacture of a tablet of rifaximin and tablet of rifaximin |
| CA3142214A1 (en) | 2019-06-03 | 2020-12-10 | Bausch Health Ireland Limited | Use of methylnaltrexone and rifaximin for treatment of increased gut permeability or associated disorders |
| EP4034091A1 (en) | 2019-09-24 | 2022-08-03 | Bausch Health Ireland Limited | Rifaximin liquid formulations |
| WO2021191312A1 (en) | 2020-03-24 | 2021-09-30 | Bausch Health Ireland Limited | Methods of treating covid-19 with rifaximin |
| WO2021229480A1 (en) * | 2020-05-15 | 2021-11-18 | Atra Pharmaceuticals Limited | Polymorph of rifaximin, process for the preparation thereof and pharmaceutical composition containing rifaximin |
| JP2023531268A (ja) | 2020-06-26 | 2023-07-21 | バウシュ ヘルス アイルランド リミテッド | 標的化放出リファキシミン組成物 |
| WO2022090490A1 (en) | 2020-10-29 | 2022-05-05 | Bausch Health Ireland Limited | Rifaximin liquid formulations for use in the treatment of sickle cell disease |
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|---|---|---|---|---|
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| IT1154655B (it) * | 1980-05-22 | 1987-01-21 | Alfa Farmaceutici Spa | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
| CA1215976A (en) | 1984-05-15 | 1986-12-30 | Vincenzo Cannata | New process for the synthesis of imidazo rifamycins |
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| IT1199413B (it) | 1984-09-26 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
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| ES2075454T3 (es) * | 1990-06-29 | 1995-10-01 | Lepetit Spa | Forma cristalina pura de rifapentina. |
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| UA75365C2 (en) * | 2000-08-16 | 2006-04-17 | Bristol Myers Squibb Co | Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon |
| WO2002036542A1 (en) * | 2000-10-31 | 2002-05-10 | Ciba Specialty Chemicals Holding Inc. | Crystalline forms of venlafaxine hydrochloride |
| IL156055A0 (en) * | 2000-11-30 | 2003-12-23 | Teva Pharma | Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms |
| ITMI20032144A1 (it) * | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
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