PE20210138A1 - TIOFENOCARBOXAMIDAS SUSTITUIDAS Y ANAìLOGOS DE LAS MISMAS - Google Patents
TIOFENOCARBOXAMIDAS SUSTITUIDAS Y ANAìLOGOS DE LAS MISMASInfo
- Publication number
- PE20210138A1 PE20210138A1 PE2020002204A PE2020002204A PE20210138A1 PE 20210138 A1 PE20210138 A1 PE 20210138A1 PE 2020002204 A PE2020002204 A PE 2020002204A PE 2020002204 A PE2020002204 A PE 2020002204A PE 20210138 A1 PE20210138 A1 PE 20210138A1
- Authority
- PE
- Peru
- Prior art keywords
- hydrogen
- alkyl
- atom
- bromine
- compound
- Prior art date
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 15
- 229910052739 hydrogen Inorganic materials 0.000 abstract 14
- 239000001257 hydrogen Substances 0.000 abstract 14
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 10
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 7
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 5
- 229910052801 chlorine Inorganic materials 0.000 abstract 5
- 229910052799 carbon Inorganic materials 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 4
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 3
- 229910052794 bromium Inorganic materials 0.000 abstract 3
- 239000000460 chlorine Substances 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical group CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000005490 tosylate group Chemical group 0.000 abstract 2
- 125000002827 triflate group Chemical group FC(S(=O)(=O)O*)(F)F 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 241000589634 Xanthomonas Species 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- DENPQNAWGQXKCU-UHFFFAOYSA-N thiophene-2-carboxamide Chemical class NC(=O)C1=CC=CS1 DENPQNAWGQXKCU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/10—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
- A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
- A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/76—1,3-Oxazoles; Hydrogenated 1,3-oxazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P13/00—Herbicides; Algicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/0825—Preparations of compounds not comprising Si-Si or Si-cyano linkages
- C07F7/083—Syntheses without formation of a Si-C bond
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
La presente invencion se refiere a un compuesto de formula (I), donde: R1 y R2 son identicos y son un atomo de cloro o un atomo de bromo; R3 es metilo; R4 es hidrogeno, alquilo C1-C6, aralquilo, entre otros; R5 es hidrogeno, o R4 y R5 forman juntos con el atomo de carbono al cual estan unidos un ciclopropilo; R6 es hidrogeno, alquilo C1-C6, entre otros. Tambien se refiere a un proceso de obtencion de dicho compuesto. Adicionalmente, la presente invencion se refiere a: i) un compuesto de formula (VIa), donde: R1 y R2 son identicos y son un atomo de cloro o bromo; R4 es hidrogeno, alquilo C1-C6, aralquilo, entre otros; R5 es un atomo de hidrogeno, o R4 y R5 forman junto con el atomo de carbono al cual estan unidos un ciclopropilo; R6 es hidrogeno, alquilo C1-C6, entre otros; U2a es bromo, iodo, un grupo mesilato, un grupo tosilato o un grupo triflato, con la condicion de que cuando R1 y R2 son atomos de bromo, U2a no es un atomo de bromo; ii) un compuesto de formula (VIIIa), donde: R1 y R2 son identicos y son un atomo de cloro o un atomo de bromo; U1a es un grupo hidroxi o un grupo alcoxi C1-C6; y U2a es un grupo mesilato, un grupo tosilato o un grupo triflato; iii) un compuesto de formula (IXa) o (IXb), donde: R3 es metilo; R4 es hidrogeno, alquilo C1-C6, aralquilo, entre otros; R5 es hidrogeno, o R4 y R5 juntos con el atomo de carbono al cual estan unidos forman un ciclopropilo; R6 es hidrogeno; alquilo C1-C6, entre otros; U4a y U5a son cloro o bromo; y iv) un compuesto de formula (Xa) o (Xb), donde: R1 o R2 son cloro o bromo; R3 es metilo; R4 es hidrogeno, alquilo C1-C6, aralquilo, entre otros; R5 es hidrogeno o R4 y R5 forman junto con el atomo de carbono al cual estan unidos, un ciclopropilo; R6 es hidrogeno, alquilo C1-C6, entre otros; donde R4 es hidrogeno, alquilo C1-C6, aralquilo, entre otros, y R5 es hidrogeno cuando R6 es hidrogeno o alquilo C1-C6. Dichos compuestos son tiofenocarboxamidas sustituidas y analogos de estas que pueden usarse para proteger a los cultivos de enfermedades bacterianas, en particular de enfermedades bacterianas causadas por bacterias que pertenecen al genero Xanthomonas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18181930 | 2018-07-05 | ||
| PCT/EP2019/067824 WO2020007902A1 (en) | 2018-07-05 | 2019-07-03 | Substituted thiophenecarboxamides and analogues as antibacterials agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20210138A1 true PE20210138A1 (es) | 2021-01-21 |
Family
ID=62874661
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2020002204A PE20210138A1 (es) | 2018-07-05 | 2019-07-03 | TIOFENOCARBOXAMIDAS SUSTITUIDAS Y ANAìLOGOS DE LAS MISMAS |
| PE2020002205A PE20210139A1 (es) | 2018-07-05 | 2019-07-03 | Tiofenocarboxamidas sustituidas y analogos como agentes antibacterianos |
| PE2020002207A PE20210183A1 (es) | 2018-07-05 | 2019-07-03 | Tiofenocarboxamidas sustituidas y analogos de las mismas |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2020002205A PE20210139A1 (es) | 2018-07-05 | 2019-07-03 | Tiofenocarboxamidas sustituidas y analogos como agentes antibacterianos |
| PE2020002207A PE20210183A1 (es) | 2018-07-05 | 2019-07-03 | Tiofenocarboxamidas sustituidas y analogos de las mismas |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US11401254B2 (es) |
| EP (3) | EP3818049B1 (es) |
| JP (3) | JP7361056B2 (es) |
| KR (3) | KR102830548B1 (es) |
| CN (3) | CN112638894B (es) |
| AR (3) | AR115699A1 (es) |
| AU (3) | AU2019297400B2 (es) |
| CA (3) | CA3105410A1 (es) |
| CL (3) | CL2020003442A1 (es) |
| CO (3) | CO2020016675A2 (es) |
| CR (3) | CR20200641A (es) |
| EC (3) | ECSP20084434A (es) |
| ES (3) | ES2932727T3 (es) |
| HU (2) | HUE060281T2 (es) |
| MA (3) | MA53089B1 (es) |
| MX (3) | MX2021000033A (es) |
| PE (3) | PE20210138A1 (es) |
| PH (3) | PH12021550014A1 (es) |
| PL (3) | PL3818050T3 (es) |
| PT (3) | PT3818050T (es) |
| TW (3) | TWI823961B (es) |
| UA (3) | UA127855C2 (es) |
| WO (3) | WO2020007902A1 (es) |
| ZA (3) | ZA202100785B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20200641A (es) | 2018-07-05 | 2021-02-16 | Bayer Ag | Tiofenocarboxamidas sustituidas y analogos como agentes antibacterianos |
| CR20210678A (es) * | 2019-07-03 | 2022-02-15 | Bayer Ag | Carboxamidas de tiofeno sustituidas y derivados de estas |
| US12492196B2 (en) * | 2019-12-20 | 2025-12-09 | Bayer Aktiengesellschaft | Thienyloxazolones and analogues |
| ES3028757T3 (en) * | 2019-12-20 | 2025-06-20 | Bayer Ag | Substituted thiophene carboxamides and derivatives thereof |
| EP4285723A3 (en) * | 2019-12-20 | 2024-03-27 | Bayer Aktiengesellschaft | Substituted thiophene carboxamides, thiophene carboxylic acids and derivatives thereof |
| PL4077303T3 (pl) * | 2019-12-20 | 2024-10-28 | Bayer Aktiengesellschaft | Podstawione tiofenokarboksyamidy i ich pochodne jako mikrobiocydy |
| CN113233993B (zh) * | 2021-05-18 | 2022-07-01 | 贵州大学 | 一种阿魏酸酰胺衍生物及其合成方法 |
| CN117645875B (zh) * | 2024-01-29 | 2024-04-09 | 云南省生态环境科学研究院 | 一种微生物修复有机污染土壤改良剂 |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1563735A (es) * | 1967-12-08 | 1969-04-18 | ||
| DE3639877A1 (de) | 1986-11-21 | 1988-05-26 | Bayer Ag | Hetarylalkyl substituierte 5- und 6-ringheterocyclen |
| JPH03204875A (ja) * | 1989-10-03 | 1991-09-06 | Wakamoto Pharmaceut Co Ltd | テトラゾール酢酸誘導体、及び該誘導体を有効成分とするアルドースレダクターゼ阻害剤 |
| DE4011172A1 (de) * | 1990-04-06 | 1991-10-10 | Degussa | Verbindungen zur bekaempfung von pflanzenkrankheiten |
| US5245551A (en) | 1991-04-10 | 1993-09-14 | University Of Utah Research Foundation | Method of determining extinction coefficient of fluorescent dye and protein concentration of dye-protein conjugate |
| DE4412333A1 (de) * | 1994-04-11 | 1995-10-12 | Bayer Ag | Mikrobizide Mittel auf Basis von Dibrom-thiophen-carbonsäure-Derivaten |
| US5516730A (en) | 1994-08-26 | 1996-05-14 | Memc Electronic Materials, Inc. | Pre-thermal treatment cleaning process of wafers |
| DE4441626A1 (de) | 1994-11-23 | 1996-05-30 | Boehringer Mannheim Gmbh | Verfahren zum besonders sensitiven Nachweis von Nukleinsäuren |
| JPH0931069A (ja) * | 1995-07-24 | 1997-02-04 | Nissan Chem Ind Ltd | チアゾールカルボン酸誘導体および植物病害防除剤 |
| US5965606A (en) * | 1995-12-29 | 1999-10-12 | Allergan Sales, Inc. | Methods of treatment with compounds having RAR.sub.α receptor specific or selective activity |
| DK0981540T3 (da) | 1997-05-09 | 2006-11-06 | Agraquest Inc | Ny Bacillus-stamme til bekæmpelse af plantesygdomme og af majsrodgnaver |
| US6245551B1 (en) | 1999-03-30 | 2001-06-12 | Agraquest, Inc. | Strain of Bacillus pumilus for controlling plant diseases caused by fungi |
| JP2000336080A (ja) | 1999-05-28 | 2000-12-05 | Nippon Bayer Agrochem Co Ltd | イソチアゾールカルボキサミド類 |
| JP4071036B2 (ja) | 2001-11-26 | 2008-04-02 | クミアイ化学工業株式会社 | バシルスｓｐ．Ｄ７４７菌株およびそれを用いた植物病害防除剤および害虫防除剤 |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| DE10239481A1 (de) * | 2002-08-28 | 2004-03-04 | Bayer Cropscience Ag | Heterocyclylcarbonyl-aminocyclopropancarbonsäure-derivate |
| GB0225554D0 (en) * | 2002-11-01 | 2002-12-11 | Syngenta Participations Ag | Chemical compounds |
| DE10301419A1 (de) * | 2003-01-16 | 2004-07-29 | Bayer Cropscience Ag | Spiroverbindungen |
| TWI312272B (en) | 2003-05-12 | 2009-07-21 | Sumitomo Chemical Co | Pyrimidine compound and pests controlling composition containing the same |
| GB0414438D0 (en) | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
| CN1977297B (zh) | 2004-06-30 | 2011-09-14 | 优泊公司 | 模具内成型用标签 |
| WO2006040646A1 (en) * | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Benzimidazole or indole amides as inhibitors of pin1 |
| CA2581725C (en) | 2004-10-20 | 2013-01-08 | Kumiai Chemical Industry Co., Ltd. | 3-triazolylphenyl sulfide derivative, and insecticide, miticide and nematicide containing it as an active ingredient |
| PE20070171A1 (es) | 2005-06-30 | 2007-03-08 | Boehringer Ingelheim Int | GLICINAMIDAS SUSTITUIDAS CON EFECTO ANTITROMBOTICO E INHIBIDOR DEL FACTOR Xa |
| CN102936221B (zh) | 2005-10-06 | 2014-09-10 | 日本曹达株式会社 | 桥联环状胺化合物以及有害生物防除剂 |
| WO2007098356A1 (en) | 2006-02-16 | 2007-08-30 | Neurocrine Biosciences, Inc. | Congeners of milnacipran as monoamine re-uptake |
| CA2668859A1 (en) * | 2006-11-07 | 2008-05-15 | Proteologics Ltd. | Pyrimidine derivatives as posh and posh-ap inhibitors |
| AR065616A1 (es) | 2007-03-07 | 2009-06-17 | Sanofi Aventis | Sintesis regioselectiva de ullmann de acido 4- bromo-3- metil-5- propoxi- tiofeno-2- carboxilico |
| WO2008157844A1 (en) * | 2007-06-21 | 2008-12-24 | Forest Laboratories Holdings Limited | Novel piperazine derivatives as inhibitors of stearoyl-coa desaturase |
| JP2009078991A (ja) | 2007-09-25 | 2009-04-16 | Mitsui Chemicals Inc | チオフェンカルボン酸誘導体およびその製造方法、並びに殺菌剤 |
| BRPI0822486B1 (pt) | 2008-03-21 | 2019-04-02 | Trentino Sviluppo S.P.A. | Trichoderma atroviride sc1 para controle biológico de doenças fúngicas em plantas |
| JP5268461B2 (ja) | 2008-07-14 | 2013-08-21 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤 |
| CN101337937B (zh) | 2008-08-12 | 2010-12-22 | 国家农药创制工程技术研究中心 | 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物 |
| CN101337940B (zh) | 2008-08-12 | 2012-05-02 | 国家农药创制工程技术研究中心 | 具杀虫活性的含氮杂环二氯烯丙醚类化合物 |
| CN101715774A (zh) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | 一个具有杀虫活性化合物制备及用途 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| GB0820344D0 (en) | 2008-11-06 | 2008-12-17 | Syngenta Ltd | Herbicidal compositions |
| CA2746394C (en) | 2008-12-12 | 2017-08-29 | Syngenta Limited | Spiroheterocyclic n-oxypiperidines as pesticides |
| PL2379537T3 (pl) * | 2008-12-19 | 2013-03-29 | Elanco Tiergesundheit Ag | Pochodne izooksazoliny i ich zastosowanie jako pestycydów |
| WO2011085575A1 (zh) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | 邻杂环甲酰苯胺类化合物及其合成方法和应用 |
| AR081721A1 (es) | 2010-02-25 | 2012-10-17 | Nippon Soda Co | Compuesto de amina ciclica y acaricida |
| BR112012030408A2 (pt) | 2010-05-31 | 2015-09-29 | Syngenta Participations Ag | método de melhoramento de culturas |
| EP2604606B1 (en) * | 2010-08-09 | 2014-10-08 | Pharmadesign, Inc. | Inhibitor of casein kinase 1delta and casein kinase 1epsilon |
| WO2012029672A1 (ja) | 2010-08-31 | 2012-03-08 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 有害生物防除剤 |
| CN101967139B (zh) | 2010-09-14 | 2013-06-05 | 中化蓝天集团有限公司 | 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用 |
| JP2013540160A (ja) | 2010-10-22 | 2013-10-31 | ヤンセン ファーマシューティカ エヌ．ベー． | モノアシルグリセロールリパーゼ阻害剤としてのアミノ−ピロリジン−アゼチジンジアミド |
| US20120121455A1 (en) * | 2010-10-29 | 2012-05-17 | Sloan Valve Company | Low lead ingot |
| CN103313971B (zh) * | 2010-11-15 | 2015-12-02 | 拜耳知识产权有限责任公司 | N-芳基吡唑（硫代）甲酰胺 |
| BR112013021602A2 (pt) | 2011-02-23 | 2019-09-24 | Lupin Ltd | derivados de heteroarila como moduladores de nachr alfa7. |
| WO2013050317A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Limited | Polymorphs of an isoxazoline derivative |
| CN102391261A (zh) | 2011-10-14 | 2012-03-28 | 上海交通大学 | 一种n-取代噁二嗪类化合物及其制备方法和应用 |
| TWI566701B (zh) | 2012-02-01 | 2017-01-21 | 日本農藥股份有限公司 | 芳烷氧基嘧啶衍生物及包含該衍生物作為有效成分的農園藝用殺蟲劑及其使用方法 |
| US9334238B2 (en) | 2012-03-30 | 2016-05-10 | Basf Se | N-substituted pyridinylidenes for combating animal pests |
| EP2647626A1 (en) | 2012-04-03 | 2013-10-09 | Syngenta Participations AG. | 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides |
| US8901153B2 (en) | 2012-04-27 | 2014-12-02 | Dow Agrosciences, Llc. | Pesticidal compositions and processes related thereto |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| CN103109816B (zh) | 2013-01-25 | 2014-09-10 | 青岛科技大学 | 硫代苯甲酰胺类化合物及其应用 |
| CN103232431B (zh) | 2013-01-25 | 2014-11-05 | 青岛科技大学 | 一种二卤代吡唑酰胺类化合物及其应用 |
| US20140275503A1 (en) | 2013-03-13 | 2014-09-18 | Dow Agrosciences Llc | Process for the preparation of certain triaryl rhamnose carbamates |
| BR112015029268B1 (pt) | 2013-05-23 | 2020-10-20 | Syngenta Participations Ag | composição pesticida, pacote de combinação, utilização, método de aumento da eficácia e redução da fitotoxicidade de compostos de ácido tetrâmico ativos em termos pesticidas, método não terapêutico para combater e controlar pragas |
| CN103265527B (zh) | 2013-06-07 | 2014-08-13 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物及其制备方法和应用 |
| CN103524422B (zh) | 2013-10-11 | 2015-05-27 | 中国农业科学院植物保护研究所 | 苯并咪唑衍生物及其制备方法和用途 |
| JP2016534997A (ja) * | 2013-10-16 | 2016-11-10 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | Ｎ−シクロアルキル−ｎ−（ビヘテロシクリルメチレン）−（チオ）カルボキサミド誘導体 |
| WO2015058021A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| CA2925595A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| TW201613866A (en) | 2014-07-07 | 2016-04-16 | Bayer Cropscience Ag | Process for preparing fluorinated iminopyridine compounds |
| PE20171735A1 (es) | 2015-02-17 | 2017-12-04 | Nippon Soda Co | Composicion agroquimica |
| KR102859105B1 (ko) | 2015-03-26 | 2025-09-12 | 바이엘 크롭사이언스 엘피 | 신규 파에니바실루스 균주, 항진균 화합물, 및 그의 사용 방법 |
| CR20200641A (es) * | 2018-07-05 | 2021-02-16 | Bayer Ag | Tiofenocarboxamidas sustituidas y analogos como agentes antibacterianos |
| CR20210678A (es) * | 2019-07-03 | 2022-02-15 | Bayer Ag | Carboxamidas de tiofeno sustituidas y derivados de estas |
| US12492196B2 (en) * | 2019-12-20 | 2025-12-09 | Bayer Aktiengesellschaft | Thienyloxazolones and analogues |
| ES3028757T3 (en) * | 2019-12-20 | 2025-06-20 | Bayer Ag | Substituted thiophene carboxamides and derivatives thereof |
| EP4285723A3 (en) * | 2019-12-20 | 2024-03-27 | Bayer Aktiengesellschaft | Substituted thiophene carboxamides, thiophene carboxylic acids and derivatives thereof |
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