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PE20199A1 - Pirazoles parasiticidas - Google Patents

Pirazoles parasiticidas

Info

Publication number
PE20199A1
PE20199A1 PE1997001081A PE00108197A PE20199A1 PE 20199 A1 PE20199 A1 PE 20199A1 PE 1997001081 A PE1997001081 A PE 1997001081A PE 00108197 A PE00108197 A PE 00108197A PE 20199 A1 PE20199 A1 PE 20199A1
Authority
PE
Peru
Prior art keywords
formula
preferred
halogen
alkyl
kpa
Prior art date
Application number
PE1997001081A
Other languages
English (en)
Inventor
Bernard Joseph Banks
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625290.3A external-priority patent/GB9625290D0/en
Priority claimed from GBGB9702235.4A external-priority patent/GB9702235D0/en
Priority claimed from GBGB9712045.5A external-priority patent/GB9712045D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of PE20199A1 publication Critical patent/PE20199A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)

Abstract

SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: R1 ES DE PREFERENCIA 2,6-DICLORO-4-TRIFLUOROMETILFENILO, 2,6-DICLORO-4-PENTAFLUOROTIOFENILO o 3-CLORO-5-TRIFLUOROMETILPIRIDIN-2-ILO; R3 ES DE PREFERENCIA CIANO; R5 ES H, ALQUILO C1-C4, NH2 o HALOGENO; R2 Y R4 SON DE PREFERENCIA IGUALES Y SON H, Cl o Br; R6 Y R8 SON DE PREFERENCIA H; R7 ES DE PREFERENCIA H, CF3 o CCl2F. TAMBIEN SE REFIERE AL COMPUESTO INTERMEDIO DE FORMULA (VII), EN DONDE: Ar ES FENILO o NAFTILO, OPCIONALMENTE SUSTITUIDOS CON ALQUILO C1-C4, ALCOXI C1-C4 o HALOGENO, DE PREFERENCIA, Ar ES 4-METILFENILO; R5 ES H, ALQUILO C1-C4 o HALOGENO; R7 ES H o ALQUILO OPCIONALMENTE SUSTITUIDO CON UNO O MAS HALOGENOS; R1 Y R3 SON COMO SE HA INDICADO PARA (I). ADEMAS SE REFIERE A LOS PROCEDIMIENTOS DE PREPARACION DEL COMPUESTO DE FORMULA (I), UNO DE LOS CUALES COMPRENDE: TERMOLISIS DE UN DERIVADO DE SAL DE METAL ALCALINO DE UN COMPUESTO DE FORMULA (VII), EN PRESENCIA DE ACETATO DE RODIO (II), UN ALQUENO DE FORMULA (R2)(R4)C=C(R6)(R8) Y DICLOROMETANO, EN DONDE: DICHA REACCION SE LLEVA A CABO A UNA PRESION DE 101 kPa A 2757 kPa Y A UNA TEMPERATURA DE APROXIMADAMENTE LA TEMPERATURA AMBIENTE A 80�C. LOS COMPUESTOS DE FORMULA (I) SON UTILES EN MEDICINA, VETERINARIA O AGRICULTURA, PARA EL CONTROL DE LAS INFESTACIONES PRODUCIDAS POR ACAROS, ARTROPODOS E INSECTOS, ENTRE OTROS
PE1997001081A 1996-12-05 1997-12-01 Pirazoles parasiticidas PE20199A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9625290.3A GB9625290D0 (en) 1996-12-05 1996-12-05 Parasiticidal agents
GBGB9702235.4A GB9702235D0 (en) 1997-02-04 1997-02-04 Parasiticidal agents
GBGB9712045.5A GB9712045D0 (en) 1997-06-10 1997-06-10 Parasiticidal agents

Publications (1)

Publication Number Publication Date
PE20199A1 true PE20199A1 (es) 1999-03-05

Family

ID=27268619

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1997001081A PE20199A1 (es) 1996-12-05 1997-12-01 Pirazoles parasiticidas

Country Status (39)

Country Link
US (2) US6075043A (es)
EP (1) EP0946515B1 (es)
JP (2) JP3950483B2 (es)
KR (1) KR100354311B1 (es)
CN (1) CN1106386C (es)
AR (1) AR013879A1 (es)
AT (1) ATE233736T1 (es)
AU (1) AU720705B2 (es)
BG (1) BG64127B1 (es)
BR (1) BR9713565A (es)
CA (1) CA2273951C (es)
CO (1) CO5031251A1 (es)
CZ (1) CZ295295B6 (es)
DE (1) DE69719547T2 (es)
DK (1) DK0946515T3 (es)
DZ (1) DZ2360A1 (es)
EA (1) EA002278B1 (es)
ES (1) ES2191870T3 (es)
HR (1) HRP970663B1 (es)
HU (1) HUP0000544A3 (es)
ID (1) ID21556A (es)
IL (1) IL129866A (es)
IS (1) IS1982B (es)
MA (1) MA24414A1 (es)
MY (1) MY117021A (es)
NO (2) NO992736D0 (es)
NZ (1) NZ335611A (es)
OA (1) OA11055A (es)
PA (1) PA8442101A1 (es)
PE (1) PE20199A1 (es)
PL (1) PL190926B1 (es)
PT (1) PT946515E (es)
RS (1) RS49720B (es)
SK (1) SK285203B6 (es)
TN (1) TNSN97197A1 (es)
TW (1) TW524667B (es)
UA (1) UA60321C2 (es)
UY (2) UY24798A1 (es)
WO (1) WO1998024767A1 (es)

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JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
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Also Published As

Publication number Publication date
UA60321C2 (uk) 2003-10-15
CO5031251A1 (es) 2001-04-27
IS1982B (is) 2005-01-14
YU25299A (sh) 2002-10-18
HK1029111A1 (en) 2001-03-23
BG103454A (en) 2000-01-31
BR9713565A (pt) 2000-03-14
DE69719547D1 (de) 2003-04-10
HUP0000544A3 (en) 2002-01-28
KR20000057432A (ko) 2000-09-15
CA2273951C (en) 2003-04-01
NZ335611A (en) 2001-01-26
BG64127B1 (bg) 2004-01-30
US6268509B1 (en) 2001-07-31
CN1106386C (zh) 2003-04-23
CZ295295B6 (cs) 2005-06-15
SK285203B6 (sk) 2006-08-03
JP3950483B2 (ja) 2007-08-01
HUP0000544A2 (hu) 2000-06-28
CN1258282A (zh) 2000-06-28
IL129866A (en) 2004-05-12
IL129866A0 (en) 2000-02-29
PT946515E (pt) 2003-06-30
ID21556A (id) 1999-06-24
NO992732L (no) 1999-08-05
RS49720B (sr) 2007-12-31
NO992732D0 (no) 1999-06-04
MA24414A1 (fr) 1998-07-01
AU720705B2 (en) 2000-06-08
US6075043A (en) 2000-06-13
OA11055A (en) 2002-03-07
KR100354311B1 (ko) 2002-09-28
NO992736D0 (no) 1999-06-04
JP2007211016A (ja) 2007-08-23
CZ195199A3 (cs) 2000-08-16
PL333922A1 (en) 2000-01-31
UY24798A1 (es) 2000-09-29
HRP970663A2 (en) 1998-10-31
PA8442101A1 (es) 2000-05-24
JP2000505812A (ja) 2000-05-16
ATE233736T1 (de) 2003-03-15
AU5485998A (en) 1998-06-29
EA199900447A1 (ru) 2000-02-28
NO313518B1 (no) 2002-10-14
DK0946515T3 (da) 2003-07-14
EA002278B1 (ru) 2002-02-28
IS5050A (is) 1999-05-11
DZ2360A1 (fr) 2002-12-28
TW524667B (en) 2003-03-21
ES2191870T3 (es) 2003-09-16
SK74099A3 (en) 2001-02-12
EP0946515B1 (en) 2003-03-05
MY117021A (en) 2004-04-30
AR013879A1 (es) 2001-01-31
CA2273951A1 (en) 1998-06-11
DE69719547T2 (de) 2003-10-02
UY24923A1 (es) 1998-09-01
WO1998024767A1 (en) 1998-06-11
EP0946515A1 (en) 1999-10-06
TNSN97197A1 (fr) 2005-03-15
PL190926B1 (pl) 2006-02-28
HRP970663B1 (en) 2003-10-31

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