PE20180327A1 - Proceso para preparar 4-amino-piridazinas - Google Patents
Proceso para preparar 4-amino-piridazinasInfo
- Publication number
- PE20180327A1 PE20180327A1 PE2017002379A PE2017002379A PE20180327A1 PE 20180327 A1 PE20180327 A1 PE 20180327A1 PE 2017002379 A PE2017002379 A PE 2017002379A PE 2017002379 A PE2017002379 A PE 2017002379A PE 20180327 A1 PE20180327 A1 PE 20180327A1
- Authority
- PE
- Peru
- Prior art keywords
- prepare
- dichloropyridazinamine
- compound
- formula
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B31/00—Reduction in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B39/00—Halogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Esta referido a un proceso para preparar un compuesto de piridazinamina de formula V, que comprende la etapa de hacer reaccionar (a) un compuesto de dicloropiridazinamina de formula IVa, o (b) un compuesto de dicloropiridazinamina de formula IVb, (c) o mezclas de (a) y (b) con hidrogeno en presencia de un catalizador de hidrogenacion, en donde R1 es H, alquilo C1-C2, o alcoxi C1-C2-alquilo C1-C2. Tambien se refiere a los nuevos compuestos de dicloropiridazinamina de formulas IVa, IVb, o mezclas de las mismas, en donde el grupo amino es un grupo etilamino
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562159392P | 2015-05-11 | 2015-05-11 | |
| EP15169166 | 2015-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20180327A1 true PE20180327A1 (es) | 2018-02-13 |
Family
ID=53274420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017002379A PE20180327A1 (es) | 2015-05-11 | 2016-05-10 | Proceso para preparar 4-amino-piridazinas |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10584102B2 (es) |
| EP (2) | EP3294725B1 (es) |
| JP (1) | JP6833718B2 (es) |
| KR (2) | KR102585412B1 (es) |
| CN (1) | CN107592859A (es) |
| AU (1) | AU2016260784B2 (es) |
| BR (1) | BR112017023935B1 (es) |
| CA (2) | CA3187499A1 (es) |
| CL (1) | CL2017002813A1 (es) |
| CO (1) | CO2017012403A2 (es) |
| ES (1) | ES2882543T3 (es) |
| IL (1) | IL255302B (es) |
| MX (2) | MX390421B (es) |
| PE (1) | PE20180327A1 (es) |
| RU (1) | RU2742663C2 (es) |
| WO (1) | WO2016180833A1 (es) |
| ZA (1) | ZA201708142B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015295287B2 (en) | 2014-07-31 | 2019-07-04 | Basf Se | Process for preparing pyrazoles |
| CN107848922A (zh) | 2015-05-08 | 2018-03-27 | 巴斯夫农业公司 | 柠檬烯‑4‑醇的制备方法 |
| BR112017023932A2 (pt) | 2015-05-08 | 2018-07-17 | Basf Agro Bv | processo para a preparação de epóxido de terpinoleno |
| WO2016180833A1 (en) | 2015-05-11 | 2016-11-17 | Basf Se | Process for preparing 4-amino-pyridazines |
| WO2017133942A1 (en) | 2016-02-02 | 2017-08-10 | Basf Se | Catalytic hydrogenation process for preparing pyrazoles |
| AU2017284971B2 (en) | 2016-06-15 | 2021-01-21 | BASF Agro B.V. | Process for the epoxidation of a tetrasubstituted alkene |
| ES2833202T3 (es) | 2016-06-15 | 2021-06-14 | Basf Agro Bv | Procedimiento para la epoxidación de un alqueno tetrasustituido |
| US10526264B2 (en) | 2016-07-07 | 2020-01-07 | Basf Se | Oxy-cope rearrangement for the manufacture of insecticidal cyclopentene compounds |
| WO2018082964A1 (en) | 2016-11-04 | 2018-05-11 | Basf Se | Process for the production of pyridazinyl-amides in a one-pot synthesis |
| DK3535257T3 (da) | 2016-11-04 | 2021-03-01 | Basf Se | Fremgangsmåde til oprensning af pyrazolpyridaziner |
| US10538493B2 (en) | 2016-11-17 | 2020-01-21 | Basf Se | Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol |
| ES2927792T3 (es) | 2017-02-14 | 2022-11-10 | Basf Se | Formulación estable de piridazinpirazolamidas plaguicidas |
| EP3601202B1 (en) | 2017-03-20 | 2023-05-10 | Basf Se | Process for preparing bromotrichloromethane |
| PT3908584T (pt) * | 2019-01-11 | 2023-05-31 | Basf Se | Formas cristalinas de 1-(1,2-dimetilpropil)-n-etil-5- metil-n-piridazin-4-il-pirazol-4-carboxamida |
| MX2021013408A (es) | 2019-05-03 | 2021-12-10 | Basf Se | Estabilizacion de concentrados en suspension mediante lignosulfonato altamente sulfonado. |
| EP3962270B1 (en) | 2019-05-03 | 2025-07-23 | Basf Se | Stabilization of suspension concentrates by hydrophobic fumed silica |
| PL3962269T3 (pl) | 2019-05-03 | 2025-11-03 | Basf Se | Stabilizacja koncentratów w postaci stężonej zawiesiny z użyciem etoksylowanego rycynooleinianu |
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| US4A (en) * | 1836-08-10 | Thomas Blanchard | Stock shaving or rounding machine for edges ends etc of ships' tackle-blocks | |
| US4728355A (en) * | 1985-10-10 | 1988-03-01 | Fmc Corporation | Pyridazinylurea plant regulators |
| RU2069660C1 (ru) * | 1994-08-23 | 1996-11-27 | Акционерное общество открытого типа "Научно-исследовательский и проектный институт азотной промышленности и продуктов органического синтеза" | Способ получения производных 4-аминопиридина |
| DE4430757A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue 4-Aminopyridazine, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
| TW406075B (en) * | 1994-12-13 | 2000-09-21 | Upjohn Co | Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds |
| ES2172670T3 (es) * | 1995-07-06 | 2002-10-01 | Novartis Ag | Pirrolpirimidinas y procedimientos para su preparacion. |
| US6258822B1 (en) | 1997-08-06 | 2001-07-10 | Abbott Laboratories | Urokinase inhibitors |
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| PL354998A1 (en) | 1999-07-28 | 2004-03-22 | Aventis Pharmaceuticals Products Inc. | Substituted oxoazaheterocyclyl compounds |
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| WO2002100352A2 (en) | 2001-06-12 | 2002-12-19 | Merck & Co., Inc. | Nr2b receptor antagonists for the treatment or prevention of migraines |
| SG155941A1 (en) * | 2004-09-22 | 2009-10-29 | Janssen Pharmaceutica Nv | Inhibitors of the interaction between mdm2 and p53 |
| JP2007326784A (ja) | 2006-06-06 | 2007-12-20 | Sagami Chem Res Center | １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法 |
| US20110189167A1 (en) | 2007-04-20 | 2011-08-04 | Flynn Daniel L | Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases |
| KR20100065340A (ko) | 2007-08-27 | 2010-06-16 | 바스프 에스이 | 무척추 해충을 방제하기 위한 피라졸 화합물 |
| WO2009068652A1 (en) | 2007-11-30 | 2009-06-04 | Smithkline Beecham Corporation | 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators |
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| JP5536073B2 (ja) | 2008-09-24 | 2014-07-02 | ビーエーエスエフ ソシエタス・ヨーロピア | 無脊椎動物系害虫を防除するためのピラゾール化合物 |
| US8853125B2 (en) | 2008-09-24 | 2014-10-07 | Basf Se | Pyrazole compounds for controlling invertebrate pests |
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| WO2014063929A1 (en) * | 2012-10-23 | 2014-05-01 | Basf Se | Substituted pesticidal pyrazole compounds |
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| UA112028C2 (uk) | 2012-12-14 | 2016-07-11 | Пфайзер Лімітед | Похідні імідазопіридазину як модулятори гамка-рецептора |
| WO2015055497A1 (en) * | 2013-10-16 | 2015-04-23 | Basf Se | Substituted pesticidal pyrazole compounds |
| MX2016009945A (es) | 2014-01-31 | 2016-10-31 | Basf Se | Pirazoles para el control de plagas de invertebrados. |
| WO2015162133A1 (en) | 2014-04-22 | 2015-10-29 | Basf Se | C3-c4-cycloalkenyl-comprising pyrazoles for controlling invertebrate pests |
| WO2015169734A1 (en) | 2014-05-05 | 2015-11-12 | Basf Se | Pyrazoles for controlling invertebrate pests |
| WO2015189080A1 (en) | 2014-06-12 | 2015-12-17 | Basf Se | Pesticidally active mixtures |
| AU2015295287B2 (en) | 2014-07-31 | 2019-07-04 | Basf Se | Process for preparing pyrazoles |
| WO2016128261A2 (en) | 2015-02-11 | 2016-08-18 | Basf Se | Pesticidal mixture comprising a pyrazole compound, an insecticide and a fungicide |
| WO2016128239A1 (en) | 2015-02-11 | 2016-08-18 | Basf Se | Pesticidal mixture comprising a pyrazole compound and a biopesticide |
| WO2016128240A1 (en) | 2015-02-11 | 2016-08-18 | Basf Se | Pesticidal mixture comprising a pyrazole compound and two fungicides |
| WO2016180833A1 (en) | 2015-05-11 | 2016-11-17 | Basf Se | Process for preparing 4-amino-pyridazines |
| WO2017133942A1 (en) | 2016-02-02 | 2017-08-10 | Basf Se | Catalytic hydrogenation process for preparing pyrazoles |
-
2016
- 2016-05-10 WO PCT/EP2016/060461 patent/WO2016180833A1/en not_active Ceased
- 2016-05-10 ES ES16724331T patent/ES2882543T3/es active Active
- 2016-05-10 US US15/572,303 patent/US10584102B2/en active Active
- 2016-05-10 AU AU2016260784A patent/AU2016260784B2/en active Active
- 2016-05-10 KR KR1020177035243A patent/KR102585412B1/ko active Active
- 2016-05-10 RU RU2017142621A patent/RU2742663C2/ru active
- 2016-05-10 BR BR112017023935-3A patent/BR112017023935B1/pt active IP Right Grant
- 2016-05-10 EP EP16724331.0A patent/EP3294725B1/en active Active
- 2016-05-10 KR KR1020237033245A patent/KR102800555B1/ko active Active
- 2016-05-10 JP JP2017557929A patent/JP6833718B2/ja active Active
- 2016-05-10 PE PE2017002379A patent/PE20180327A1/es not_active Application Discontinuation
- 2016-05-10 MX MX2017014287A patent/MX390421B/es unknown
- 2016-05-10 CN CN201680026456.2A patent/CN107592859A/zh active Pending
- 2016-05-10 CA CA3187499A patent/CA3187499A1/en active Pending
- 2016-05-10 EP EP21163074.4A patent/EP3872073A1/en active Pending
- 2016-05-10 CA CA2984703A patent/CA2984703C/en active Active
-
2017
- 2017-10-29 IL IL255302A patent/IL255302B/en active IP Right Grant
- 2017-11-07 MX MX2021015546A patent/MX2021015546A/es unknown
- 2017-11-07 CL CL2017002813A patent/CL2017002813A1/es unknown
- 2017-11-30 CO CONC2017/0012403A patent/CO2017012403A2/es unknown
- 2017-11-30 ZA ZA2017/08142A patent/ZA201708142B/en unknown
-
2019
- 2019-12-31 US US16/731,289 patent/US11046656B2/en active Active
-
2021
- 2021-05-18 US US17/323,337 patent/US12162841B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |