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PE20150334A1 - Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares - Google Patents

Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares

Info

Publication number
PE20150334A1
PE20150334A1 PE2014001487A PE2014001487A PE20150334A1 PE 20150334 A1 PE20150334 A1 PE 20150334A1 PE 2014001487 A PE2014001487 A PE 2014001487A PE 2014001487 A PE2014001487 A PE 2014001487A PE 20150334 A1 PE20150334 A1 PE 20150334A1
Authority
PE
Peru
Prior art keywords
avian
vaccines
immunize
herpes viruses
region located
Prior art date
Application number
PE2014001487A
Other languages
English (en)
Inventor
Ayumi Fujisawa
Mayumi Kubomura
Sakiko Saeki
Shuji Saito
Original Assignee
Ceva Sante Animale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48040245&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20150334(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ceva Sante Animale filed Critical Ceva Sante Animale
Publication of PE20150334A1 publication Critical patent/PE20150334A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se refiere a un virus del herpes aviar recombinante, que comprende al menos dos secuencias de nucleotidos recombinantes codificando cada secuencia de nucleotidos recombinante un peptido antigenico distinto, en donde dichas al menos dos secuencias de nucleotidos recombinantes se insertan en regiones no codificantes distintas del genoma viral seleccionadas entre la region localizada entre UL44 y UL45, la region localizada entre UL45 y UL46, la region localizada entre US10 y SORF3, la region localizada entre SORF3 y US2.
PE2014001487A 2012-03-30 2013-03-29 Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares PE20150334A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20120305390 EP2644702A1 (en) 2012-03-30 2012-03-30 Multivalent recombinant avian herpes virus and vaccine for immunizing avian species

Publications (1)

Publication Number Publication Date
PE20150334A1 true PE20150334A1 (es) 2015-03-25

Family

ID=48040245

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2014001487A PE20150334A1 (es) 2012-03-30 2013-03-29 Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares
PE2019002000A PE20191704A1 (es) 2012-03-30 2013-03-29 Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2019002000A PE20191704A1 (es) 2012-03-30 2013-03-29 Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares

Country Status (22)

Country Link
US (6) US10251951B2 (es)
EP (4) EP2644702A1 (es)
JP (2) JP6505593B2 (es)
KR (1) KR102070217B1 (es)
CN (2) CN111733143A (es)
BR (1) BR112014024094A2 (es)
CA (1) CA2868132C (es)
CO (1) CO7160021A2 (es)
ES (2) ES2636464T5 (es)
HU (2) HUE035395T2 (es)
MA (1) MA37446B1 (es)
MX (1) MX357365B (es)
MY (1) MY173016A (es)
PE (2) PE20150334A1 (es)
PH (2) PH12014502162B1 (es)
PL (2) PL3219802T3 (es)
PT (2) PT3219802T (es)
RU (2) RU2658439C2 (es)
TN (1) TN2014000392A1 (es)
UA (1) UA118335C2 (es)
WO (1) WO2013144355A1 (es)
ZA (1) ZA201406979B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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EP2644702A1 (en) 2012-03-30 2013-10-02 Ceva Sante Animale Multivalent recombinant avian herpes virus and vaccine for immunizing avian species
EP2845904A1 (en) 2013-09-06 2015-03-11 Ceva Sante Animale Recombinant Marek's disease viruses and uses thereof
CN104120110B (zh) * 2014-07-11 2017-01-18 中国农业科学院哈尔滨兽医研究所 表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株及其构建方法和应用
CN107043774B (zh) * 2014-09-25 2021-05-04 中国人民解放军第二军医大学东方肝胆外科医院 一种嵌合强启动子及其用途
AR103245A1 (es) * 2014-12-24 2017-04-26 Intervet Int Bv Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada
US10537628B2 (en) * 2015-08-10 2020-01-21 The Texas A&M University System Recombinant turkey herpesvirus vaccines and uses thereof
EP3471766B1 (en) 2016-06-17 2022-12-14 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens
CN106350475A (zh) * 2016-08-26 2017-01-25 江苏省农业科学院 一种新型火鸡疱疹病毒的细菌人工染色体、构建方法与应用
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CN107815469A (zh) * 2017-10-16 2018-03-20 北京市农林科学院 一种重组火鸡疱疹病毒及其制备方法
CN108060141B (zh) * 2017-12-14 2021-05-28 天津瑞普生物技术股份有限公司 Vp2基因和np基因重组腺病毒及其应用
CN109402071B (zh) * 2018-11-08 2021-04-27 中国农业大学 一种表达h9n2亚型禽流感病毒h9蛋白的重组火鸡疱疹病毒
EP3897709A1 (en) * 2018-12-21 2021-10-27 Ceva Santé Animale Recombinant avian herpes viruses containing multiple foreign genes
WO2020136220A1 (en) 2018-12-27 2020-07-02 Ceva Sante Animale Recombinant viruses and the uses thereof
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CN110684744A (zh) * 2019-10-22 2020-01-14 青岛易邦生物工程有限公司 一种表达鸡传染性法氏囊病病毒vp2基因的重组火鸡疱疹病毒株
CN114828882A (zh) 2019-12-20 2022-07-29 英特维特国际股份有限公司 多价hvt载体疫苗
US20240252624A1 (en) 2020-06-17 2024-08-01 Teshome Mebatsion Recombinant hvt vectors expressing influenza hemagglutinin and immunogenic compositions, and production and uses thereof
EP4228683A2 (en) * 2020-10-15 2023-08-23 Ceva Santé Animale Recombinant hvt and uses thereof
CN114369580A (zh) * 2020-10-15 2022-04-19 浙江诗华诺倍威生物技术有限公司 重组hvt及其用途
EP4267179A1 (en) * 2020-12-24 2023-11-01 Intervet International B.V. Multivalent hvt vector vaccine
EP4518893A1 (en) 2022-05-05 2025-03-12 Intervet International B.V. New multivalent hvt vector vaccine
EP4619031A1 (en) 2022-11-18 2025-09-24 Ceva Sante Animale Recombinant marek's disease virus and uses thereof
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UA118651C2 (uk) 2011-11-30 2019-02-25 Меріал Інк Рекомбінантний вектор hvt, який експресує антигени патогенів птахів, та композиція, що його містить
EP2644702A1 (en) 2012-03-30 2013-10-02 Ceva Sante Animale Multivalent recombinant avian herpes virus and vaccine for immunizing avian species
EP2845904A1 (en) 2013-09-06 2015-03-11 Ceva Sante Animale Recombinant Marek's disease viruses and uses thereof

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Publication number Publication date
PT3219802T (pt) 2020-07-27
KR20150003244A (ko) 2015-01-08
ES2636464T3 (es) 2017-10-05
PE20191704A1 (es) 2019-11-27
PL2831246T5 (pl) 2025-11-12
MA20150281A2 (fr) 2015-08-31
TN2014000392A1 (en) 2015-12-21
UA118335C2 (uk) 2019-01-10
EP2831246A1 (en) 2015-02-04
JP6845266B2 (ja) 2021-03-17
EP3708670A1 (en) 2020-09-16
ES2636464T5 (en) 2025-04-03
CA2868132C (en) 2021-08-31
MA37446B1 (fr) 2016-10-31
EP3219802A1 (en) 2017-09-20
BR112014024094A2 (pt) 2017-07-18
RU2766003C2 (ru) 2022-02-07
US11730807B2 (en) 2023-08-22
US10500270B2 (en) 2019-12-10
EP2644702A1 (en) 2013-10-02
PH12014502162A1 (en) 2014-12-10
US20150118250A1 (en) 2015-04-30
ES2807952T3 (es) 2021-02-24
US20180256706A1 (en) 2018-09-13
CA2868132A1 (en) 2013-10-03
PL2831246T3 (pl) 2017-10-31
HUE035395T2 (en) 2018-05-02
US20200108137A1 (en) 2020-04-09
JP2015512633A (ja) 2015-04-30
ZA201406979B (en) 2016-01-27
MY173016A (en) 2019-12-19
EP2831246B1 (en) 2017-05-03
CN104364381A (zh) 2015-02-18
JP6505593B2 (ja) 2019-04-24
US12440555B2 (en) 2025-10-14
RU2014143830A (ru) 2016-05-27
RU2018116857A (ru) 2018-10-24
US20240082390A1 (en) 2024-03-14
CN104364381B (zh) 2020-07-28
PT2831246T (pt) 2017-08-09
RU2018116857A3 (es) 2021-06-08
EP2831246B2 (en) 2024-11-06
WO2013144355A1 (en) 2013-10-03
MX2014011754A (es) 2014-11-26
CO7160021A2 (es) 2015-01-15
HUE050602T2 (hu) 2020-12-28
EP3219802B1 (en) 2020-04-29
PL3219802T3 (pl) 2020-08-24
CN111733143A (zh) 2020-10-02
JP2019080571A (ja) 2019-05-30
US11123425B2 (en) 2021-09-21
RU2658439C2 (ru) 2018-06-21
PH12019501067A1 (en) 2020-07-06
US10245315B2 (en) 2019-04-02
PH12014502162B1 (en) 2014-12-10
MX357365B (es) 2018-07-05
US20180256707A1 (en) 2018-09-13
KR102070217B1 (ko) 2020-01-28
US10251951B2 (en) 2019-04-09
US20210401973A1 (en) 2021-12-30

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