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PE20121533A1 - Metodo para producir l-aminoacido - Google Patents

Metodo para producir l-aminoacido

Info

Publication number
PE20121533A1
PE20121533A1 PE2012000256A PE2012000256A PE20121533A1 PE 20121533 A1 PE20121533 A1 PE 20121533A1 PE 2012000256 A PE2012000256 A PE 2012000256A PE 2012000256 A PE2012000256 A PE 2012000256A PE 20121533 A1 PE20121533 A1 PE 20121533A1
Authority
PE
Peru
Prior art keywords
amino acid
produce
enhance
activity
bacteria
Prior art date
Application number
PE2012000256A
Other languages
English (en)
Inventor
Takeshi Nagahiko
Jun Nakamura
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20121533A1 publication Critical patent/PE20121533A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

SE REFIERE A UN METODO PARA PRODUCIR UN L-AMINOACIDO TAL COMO L-GLUTAMICO, L-GLUTAMINA, L-PROLINA, L-ARGININA, L-LEUCINA Y L-CISTEINA, EL CUAL COMPRENDE: A) CULTIVAR UNA BACTERIA CORINEFORME QUE TIENE CAPACIDAD PARA PRODUCIR L-AMINOACIDO, B) ACUMULAR EL L-AMINOACIDO EN EL MEDIO O CELULAS DE LA BACTERIA, Y C) RECOLECTAR EL L-AMINOACIDO DEL MEDIO O LAS CELULAS; EN DONDE DICHA BACTERIA CORINEFORME HA SIDO MODIFICADA PARA i) POTENCIAR LA ACTIVIDAD DE LA ANHIDRASA CARBONICA AUMENTANDO EL NUMERO DE COPIAS DEL GEN QUE CODIFICA LA ANHIDRASA CARBONICA O MODIFICANDO UNA SECUENCIA DE CONTROL DE EXPRESION DEL GEN, ii) IMPARTIR ACTIVIDAD DE D-XILOSA-5-FOSFATO FOSFOCETOLASA O DE FRUCTOSA-6-FOSFATO FOSFOCETOLASA, iii) POTENCIAR LA ACTIVIDAD DE FOSFOTRANSACETILASA, iv) POTENCIAR LA ACTIVIDAD DE FOSFOENOLPIRUVATO CARBOXILASA
PE2012000256A 2009-08-25 2010-07-21 Metodo para producir l-aminoacido PE20121533A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009194636A JP2012223091A (ja) 2009-08-25 2009-08-25 Ｌ−アミノ酸の製造法

Publications (1)

Publication Number Publication Date
PE20121533A1 true PE20121533A1 (es) 2012-11-27

Family

ID=43627693

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000256A PE20121533A1 (es) 2009-08-25 2010-07-21 Metodo para producir l-aminoacido

Country Status (6)

Country Link
US (1) US20120237985A1 (es)
EP (1) EP2471943B1 (es)
JP (1) JP2012223091A (es)
CN (1) CN102498216B (es)
PE (1) PE20121533A1 (es)
WO (1) WO2011024583A1 (es)

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BR112012027464A2 (pt) 2010-06-04 2019-09-24 Novozymes Inc célula hospedeira, método para produzir um ácido dicarboxílico c4, e, método para aumentar a produção de ácido dicarboxílico c4.
CN103080126B (zh) 2010-06-21 2016-05-11 诺维信股份有限公司 具有c4-二羧酸转运蛋白活性的多肽和编码该多肽的多核苷酸
BR112012028031A2 (pt) 2010-06-21 2019-09-24 Novozymes Inc célula hospedeira, e , métodos para produzir um ácido dicarboxílico c4 e para aumentar a produção de ácido dicarboxílico c4.
CN103492551A (zh) 2011-02-28 2014-01-01 诺维信股份有限公司 用于生产c4-二羧酸的微生物
ES2579706T3 (es) 2011-08-19 2016-08-16 Novozymes, Inc. Microorganismos recombinantes para la producción de ácidos C4-dicarboxílicos
KR101735935B1 (ko) 2015-07-20 2017-05-16 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
JP7066977B2 (ja) * 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
CN111040979B (zh) * 2018-10-11 2022-05-10 中国科学院天津工业生物技术研究所 一种代谢工程改造谷氨酸棒杆菌高产l-半胱氨酸的方法
CN112522175B (zh) * 2020-12-30 2023-08-18 内蒙古伊品生物科技有限公司 一种改造基因bbd29_09525产l-谷氨酸的重组菌株及其构建方法与应用
CN116286759A (zh) * 2022-12-30 2023-06-23 内蒙古伊品生物科技有限公司 氨基酸产量相关蛋白cynT及其生物材料和应用
WO2025016203A1 (zh) * 2023-07-18 2025-01-23 宁夏伊品生物科技股份有限公司 利用重组大肠杆菌生产l-精氨酸的方法及其所用重组菌
KR20250078646A (ko) * 2023-11-23 2025-06-04 대상 주식회사 L-글루탐산 생산능이 향상된 변이 미생물 및 이를 이용한 l-글루탐산의 생산 방법

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