PE20081661A1 - Marcacion radioactiva por fluoracion de aziridinas - Google Patents
Marcacion radioactiva por fluoracion de aziridinasInfo
- Publication number
- PE20081661A1 PE20081661A1 PE2007001247A PE2007001247A PE20081661A1 PE 20081661 A1 PE20081661 A1 PE 20081661A1 PE 2007001247 A PE2007001247 A PE 2007001247A PE 2007001247 A PE2007001247 A PE 2007001247A PE 20081661 A1 PE20081661 A1 PE 20081661A1
- Authority
- PE
- Peru
- Prior art keywords
- gly
- phenyl
- compounds
- aziridin
- bala
- Prior art date
Links
- 150000001541 aziridines Chemical class 0.000 title 1
- 230000002285 radioactive effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 2,4,6-TRIISOPROPYL-PHENYL-SULPHONYL Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002600 positron emission tomography Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C07D203/24—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REFIERE A COMPUESTOS DERIVADOS DE AZIRIDINA DE FORMULA (I) DONDE R ES 2,4,6-TRIISOPROPIL-FENIL-SULFONILO, 3,4-DIMETOXI-FENIL-SULFONILO, FENIL-SULFONILO, ENTRE OTROS; R1 Y R4 SON CADA UNO H, ALQUILO(C1-C6), CICLOALQUILO(C3-C20), ARILO(C6-C12), HETEROARILO DE 5 A 14 ATOMOS EN EL ANILLO, ENTRE OTROS; L ES UN CONECTOR ADECUADO PARA ACOPLAR CON EL RADICAL AGENTE DE DIRECCIONAMIENTO TAL COMO ALQUILO(C1-C6), CICLOALQUILO(C3-C20), ALQUENILO(C2-C6), ARILO(C6-C12), ENTRE OTROS; B ES EL AGENTE DE DIRECCIONAMIENTO TAL COMO PEPTIDOS, PEPTIDOMIMETICOS, MOLECULAS PEQUENAS Y OLIGONUCLEOTIDOS. SON COMPUESTOS PREFERIDOS: GLY-VAL-BALA-PHE-GLY-AMIDA DE ACIDO 1-(TOLUEN-4-SULFONIL)-AZIRIDIN-2-CARBOXILICO, GLY-VAL-BALA-PHE-GLY-AMIDA DE ACIDO 1-(2,4,6-TRIISOPROPIL-BENCENSULFONIL)-AZIRIDIN-2-CARBOXILICO, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHOS COMPUESTOS SON FLUORADOS Y MARCADOS SIENDO UTILES PARA EL DIAGNOSTICO POR IMAGENES DE TUMORES, ESCLEROSIS MULTIPLE, ARTRITIS REUMATOIDE PARA TOMOGRAFIA POR EMISION DE POSITRONES
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07090001A EP1944288A1 (en) | 2007-01-09 | 2007-01-09 | Radiolabelling via fluorination of aziridines |
| EP07090079A EP1985624A3 (en) | 2007-04-23 | 2007-04-23 | Single step method of radiofluorination of biologically active compounds or biomolecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20081661A1 true PE20081661A1 (es) | 2009-01-18 |
Family
ID=38941926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2007001247A PE20081661A1 (es) | 2007-01-09 | 2007-09-14 | Marcacion radioactiva por fluoracion de aziridinas |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20090022664A1 (es) |
| EP (1) | EP2099747A1 (es) |
| JP (1) | JP2010522140A (es) |
| KR (1) | KR20090096716A (es) |
| AR (1) | AR062856A1 (es) |
| AU (1) | AU2007343454A1 (es) |
| BR (1) | BRPI0720884A2 (es) |
| CA (1) | CA2674408A1 (es) |
| CL (1) | CL2007002673A1 (es) |
| CO (1) | CO6220852A2 (es) |
| CR (1) | CR10917A (es) |
| DO (1) | DOP2009000173A (es) |
| EC (1) | ECSP099505A (es) |
| MA (1) | MA31175B1 (es) |
| MX (1) | MX2009007395A (es) |
| NO (1) | NO20092813L (es) |
| PA (1) | PA8747801A1 (es) |
| PE (1) | PE20081661A1 (es) |
| RU (1) | RU2009130455A (es) |
| SV (1) | SV2009003328A (es) |
| TN (1) | TN2009000233A1 (es) |
| TW (1) | TW200829275A (es) |
| UY (1) | UY30594A1 (es) |
| WO (1) | WO2008083729A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8784774B2 (en) | 2011-09-16 | 2014-07-22 | General Electric Company | Labeled molecular imaging agents and methods of use |
| US9468692B2 (en) | 2014-01-23 | 2016-10-18 | General Electric Company | Labeled molecular imaging agents and methods of use |
| US9468693B2 (en) | 2014-01-23 | 2016-10-18 | General Electric Company | Labeled molecular imaging agents and methods of use |
| NL2014828B1 (en) * | 2015-05-20 | 2017-01-31 | Out And Out Chemistry S P R L | Method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, a device and cassette for performing this method. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3954994A (en) * | 1968-10-03 | 1976-05-04 | Pfizer Inc. | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents |
| JPS5810380B2 (ja) * | 1975-01-31 | 1983-02-25 | 三共株式会社 | ペプチドノ セイホウ |
| US6015790A (en) * | 1997-10-06 | 2000-01-18 | Basf Aktiengesellschaft | Methods and compositions for treating rheumatoid arthritis |
| EP2098514A1 (en) * | 1999-07-21 | 2009-09-09 | The Trustees Of The University Of Pennsylvania | Preparation of compounds useful for the detection of hypoxia |
| SE9903998D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
| US6894057B2 (en) * | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| WO2004014377A1 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | 4-hydroxyquinoline derivatives as matrix metalloproteinase inhibitors |
| GB0222909D0 (en) * | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| US6875784B2 (en) * | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
| CN1212307C (zh) * | 2003-07-23 | 2005-07-27 | 中国科学院上海有机化学研究所 | 一种合成β-氟胺化合物的方法 |
| EP1799637A1 (en) * | 2004-09-23 | 2007-06-27 | Amgen, Inc | Substituted sulfonamidopropionamides and methods of use |
| CA2602146A1 (en) * | 2005-04-07 | 2006-10-19 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
-
2007
- 2007-09-07 AU AU2007343454A patent/AU2007343454A1/en not_active Abandoned
- 2007-09-07 EP EP07802294A patent/EP2099747A1/en not_active Withdrawn
- 2007-09-07 JP JP2009545069A patent/JP2010522140A/ja active Pending
- 2007-09-07 MX MX2009007395A patent/MX2009007395A/es unknown
- 2007-09-07 BR BRPI0720884-7A patent/BRPI0720884A2/pt not_active IP Right Cessation
- 2007-09-07 CA CA002674408A patent/CA2674408A1/en not_active Abandoned
- 2007-09-07 KR KR1020097014304A patent/KR20090096716A/ko not_active Withdrawn
- 2007-09-07 RU RU2009130455/04A patent/RU2009130455A/ru not_active Application Discontinuation
- 2007-09-07 WO PCT/EP2007/007968 patent/WO2008083729A1/en not_active Ceased
- 2007-09-07 US US11/851,786 patent/US20090022664A1/en not_active Abandoned
- 2007-09-10 TW TW096133836A patent/TW200829275A/zh unknown
- 2007-09-14 PE PE2007001247A patent/PE20081661A1/es not_active Application Discontinuation
- 2007-09-14 PA PA20078747801A patent/PA8747801A1/es unknown
- 2007-09-14 AR ARP070104087A patent/AR062856A1/es unknown
- 2007-09-14 UY UY30594A patent/UY30594A1/es not_active Application Discontinuation
- 2007-09-14 CL CL200702673A patent/CL2007002673A1/es unknown
-
2009
- 2009-06-08 TN TNP2009000233A patent/TN2009000233A1/fr unknown
- 2009-07-08 DO DO2009000173A patent/DOP2009000173A/es unknown
- 2009-07-09 SV SV2009003328A patent/SV2009003328A/es not_active Application Discontinuation
- 2009-07-09 CO CO09071219A patent/CO6220852A2/es not_active Application Discontinuation
- 2009-07-09 CR CR10917A patent/CR10917A/es unknown
- 2009-07-09 EC EC2009009505A patent/ECSP099505A/es unknown
- 2009-08-06 MA MA32154A patent/MA31175B1/fr unknown
- 2009-08-07 NO NO20092813A patent/NO20092813L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MA31175B1 (fr) | 2010-02-01 |
| NO20092813L (no) | 2009-09-22 |
| CR10917A (es) | 2009-08-27 |
| PA8747801A1 (es) | 2009-08-26 |
| RU2009130455A (ru) | 2011-02-20 |
| BRPI0720884A2 (pt) | 2014-03-25 |
| KR20090096716A (ko) | 2009-09-14 |
| CA2674408A1 (en) | 2008-07-17 |
| AR062856A1 (es) | 2008-12-10 |
| CO6220852A2 (es) | 2010-11-19 |
| JP2010522140A (ja) | 2010-07-01 |
| UY30594A1 (es) | 2008-09-02 |
| SV2009003328A (es) | 2009-12-14 |
| WO2008083729A1 (en) | 2008-07-17 |
| MX2009007395A (es) | 2009-07-17 |
| CL2007002673A1 (es) | 2008-07-18 |
| TN2009000233A1 (en) | 2010-10-18 |
| EP2099747A1 (en) | 2009-09-16 |
| DOP2009000173A (es) | 2010-10-31 |
| AU2007343454A1 (en) | 2008-07-17 |
| ECSP099505A (es) | 2009-08-28 |
| US20090022664A1 (en) | 2009-01-22 |
| TW200829275A (en) | 2008-07-16 |
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