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PE20060337A1 - 17alfa-fluoroesteroides - Google Patents

17alfa-fluoroesteroides

Info

Publication number
PE20060337A1
PE20060337A1 PE2005000421A PE2005000421A PE20060337A1 PE 20060337 A1 PE20060337 A1 PE 20060337A1 PE 2005000421 A PE2005000421 A PE 2005000421A PE 2005000421 A PE2005000421 A PE 2005000421A PE 20060337 A1 PE20060337 A1 PE 20060337A1
Authority
PE
Peru
Prior art keywords
compound
17alpha
organos
carbons
alpha
Prior art date
Application number
PE2005000421A
Other languages
English (en)
Inventor
Ulrich Bothe
Bernd Menzenbach
Peter Droescher
Walter Elger
Gudrun Reddersen
Birgitt Schneider
Alexander Hillisch
Hans-Udo Schweikert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PE20060337A1 publication Critical patent/PE20060337A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

REFERIDA A UN COMPUESTO 17 ALFA-FLUOROESTEROIDE DE FORMULA I, DONDE R1 ES H O METILO; R2 Y R3 SON H, Cl, METILO; ENTRE LOS CARBONOS 6 Y 7 PUEDE HABER UNA UNION SIMPLE O DOBLE Y ENTRE LOS CARBONOS 9 Y 10 PUEDE HABER UNA UNION SIMPLE O DOBLE. ES COMPUESTO PREFERIDO (E)-17ALFA-FLUORO-3-OXO-ESTR-4-EN-17BETA-CARBALDEHIDOXIMA. TAMBIEN ESTA REFERIDA A UN PROCEDIMIENTO DE PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN A DICHO COMPUESTO, EL CUAL ES GESTAGENO E INHIBIDOR DE LA 5 ALFA-REDUCTASA, POR LO QUE ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES DE CIERTOS ORGANOS Y TEJIDOS, TANTO EN EL HOMBRE COMO EN LA MUJER, COMO CONSECUENCIA DE UN NIVEL AUMENTADO DE ANDROGENOS, TALES COMO ACNE, HIRSUTISMO, ALOPECIA, ENTRE OTRAS
PE2005000421A 2004-04-19 2005-04-15 17alfa-fluoroesteroides PE20060337A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004019406A DE102004019406A1 (de) 2004-04-19 2004-04-19 17α-Fluorsteroide

Publications (1)

Publication Number Publication Date
PE20060337A1 true PE20060337A1 (es) 2006-05-25

Family

ID=34964632

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005000421A PE20060337A1 (es) 2004-04-19 2005-04-15 17alfa-fluoroesteroides

Country Status (12)

Country Link
EP (1) EP1737880B1 (es)
JP (1) JP2007532688A (es)
AR (1) AR048829A1 (es)
AT (1) ATE464313T1 (es)
DE (2) DE102004019406A1 (es)
GT (1) GT200500092A (es)
PA (1) PA8630501A1 (es)
PE (1) PE20060337A1 (es)
SV (1) SV2006002086A (es)
TW (1) TW200538134A (es)
UY (1) UY28857A1 (es)
WO (1) WO2005100376A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202007019049U1 (de) * 2007-11-05 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Verwendung eines Gestagens in Kombination mit einem Estrogen zur Prophylaxe der Laktoseintoleranz bei der oralen Kontrazeption
US20130203718A1 (en) * 2010-05-07 2013-08-08 Marie-Edith Rafestin-Oblin Progesterone receptor antagonists and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7199115B2 (en) * 2004-04-19 2007-04-03 Schering Ag 17α-fluorosteroids, pharmaceutical compositions containing 17α-fluorosteroids and a method of making them

Also Published As

Publication number Publication date
DE502005009416D1 (de) 2010-05-27
WO2005100376A1 (de) 2005-10-27
ATE464313T1 (de) 2010-04-15
DE102004019406A1 (de) 2005-11-03
EP1737880A1 (de) 2007-01-03
AR048829A1 (es) 2006-05-31
TW200538134A (en) 2005-12-01
JP2007532688A (ja) 2007-11-15
EP1737880B1 (de) 2010-04-14
GT200500092A (es) 2006-05-09
PA8630501A1 (es) 2006-05-16
UY28857A1 (es) 2005-11-30
SV2006002086A (es) 2006-02-15

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed