[go: up one dir, main page]

PE20050962A1 - Anticuerpos completamente humanos contra 4-1bb humano - Google Patents

Anticuerpos completamente humanos contra 4-1bb humano

Info

Publication number
PE20050962A1
PE20050962A1 PE2004000974A PE2004000974A PE20050962A1 PE 20050962 A1 PE20050962 A1 PE 20050962A1 PE 2004000974 A PE2004000974 A PE 2004000974A PE 2004000974 A PE2004000974 A PE 2004000974A PE 20050962 A1 PE20050962 A1 PE 20050962A1
Authority
PE
Peru
Prior art keywords
human
seq
refers
amino acids
sequence
Prior art date
Application number
PE2004000974A
Other languages
English (en)
Inventor
Maria Jure-Kunkel
Laura J Hefta
Marc Santoro
Subinay Ganguly
Edward L Halk
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37426115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050962(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PE20050962A1 publication Critical patent/PE20050962A1/es

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UN ANTICUERPO MONOCLONAL COMPLETAMENTE HUMANO Y PORCION DE ENLACE DE ANTIGENO DEL MISMO QUE SE ENLAZA ESPECIFICAMENTE A 4-1BB, QUE COMPRENDE UNA REGION VARIABLE DE CADENA LIGERA Y UN REGION VARIABLE DE CADENA PESADA, EN DONDE LA CADENA LIGERA COMPRENDE LOS RESIDUOS DE AMINOACIDOS 21-236 DE SEQ ID NO: 6 Y LA CADENA PESADA COMPRENDE LOS RESIDUOS DE AMINOACIDOS 20-467 DE SEQ IN NO: 3. TAMBIEN SE REFIERE A UN POLINUCLEOTIDO AISLADO QUE COMPRENDE UNA SECUENCIA DE NUCLEOTIDO QUE CODIFICA LA SECUENCIA DE AMINOACIDOS ANTERIORMENTE MENCIONADOS Y A UNA COMPOSICION FARMACEUTICA QUE LOS CONTIENE, EL CUAL SE UTILIZA EN EL TRATAMIENTO DEL CANCER
PE2004000974A 2003-10-10 2004-10-11 Anticuerpos completamente humanos contra 4-1bb humano PE20050962A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51019303P 2003-10-10 2003-10-10

Publications (1)

Publication Number Publication Date
PE20050962A1 true PE20050962A1 (es) 2005-11-17

Family

ID=37426115

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000974A PE20050962A1 (es) 2003-10-10 2004-10-11 Anticuerpos completamente humanos contra 4-1bb humano

Country Status (5)

Country Link
CN (1) CN1867585B (es)
AR (1) AR046094A1 (es)
PE (1) PE20050962A1 (es)
TW (1) TWI332844B (es)
ZA (1) ZA200602834B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110357961A (zh) * 2018-04-10 2019-10-22 无锡智康弘义生物科技有限公司 抗人4-1bb单克隆抗体及其制备方法和用途
US12054554B2 (en) 2018-04-10 2024-08-06 Wuxi Biologics (Shanghai) Co., Ltd. Monoclonal antibody against human 4-1BB, method for preparing the same, and use thereof

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2810359C (en) * 2010-09-09 2021-06-22 Pfizer Inc. 4-1bb binding molecules
KR101503341B1 (ko) 2014-03-12 2015-03-18 국립암센터 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법
RU2017142008A (ru) * 2015-05-21 2019-06-24 Эллигейтор Биосайенс Аб Новые полипептиды
EP3354661B1 (en) 2015-09-22 2020-06-03 Dingfu Biotarget Co., Ltd. Fully human antibody against human cd137 and use thereof
GB201619648D0 (en) * 2016-11-21 2017-01-04 Alligator Bioscience Ab Novel antibodies and uses thereof
CA3039772C (en) 2017-01-06 2020-08-25 Eutilex Co., Ltd. Anti-human 4-1bb antibodies and uses thereof
US11987635B2 (en) * 2017-06-25 2024-05-21 Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. Anti-4-1BB antibodies and methods of making and using thereof
JP7402521B2 (ja) * 2017-07-11 2023-12-21 コンパス セラピューティクス リミテッド ライアビリティ カンパニー ヒトcd137に結合するアゴニスト性抗体およびその使用
CN111511762B (zh) * 2017-08-21 2025-05-06 天演药业公司 抗cd137分子及其用途
WO2019072274A1 (zh) * 2017-10-12 2019-04-18 瑞阳(苏州)生物科技有限公司 一种激动型4-1bb单克隆抗体
CN109651507B (zh) 2017-10-12 2021-11-26 瑞阳(苏州)生物科技有限公司 一种激动型4-1bb单克隆抗体
TWI701259B (zh) 2017-11-09 2020-08-11 大陸商上海懷越生物科技有限公司 4﹘1bb抗體及其製備方法和應用
RU2020127196A (ru) * 2018-01-22 2022-02-24 Цзянсу Хэнжуй Медицин Ко., Лтд. Антитело против 4-1bb, его антигенсвязывающий фрагмент и его медицинское применение
WO2019148445A1 (en) 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
CN112867733B (zh) * 2018-10-19 2023-01-06 苏州丁孚靶点生物技术有限公司 抗cd137抗体及其应用
CN111320691B (zh) * 2018-12-17 2022-04-05 程联胜 一种抗人4-1bb单克隆抗体及其应用
CN112010974B (zh) * 2019-05-30 2022-08-09 山东博安生物技术股份有限公司 一种特异性结合人4-1bb的抗体及其应用
CN113842456B (zh) * 2020-06-28 2022-07-26 上海齐鲁制药研究中心有限公司 一种抗人4-1bb的单克隆抗体制剂及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996029348A1 (en) * 1995-03-23 1996-09-26 Indiana University Foundation Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
JP2001502325A (ja) * 1996-10-11 2001-02-20 ブリストル―マイヤーズ・スクイブ・カンパニー 免疫調整の方法および組成物

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110357961A (zh) * 2018-04-10 2019-10-22 无锡智康弘义生物科技有限公司 抗人4-1bb单克隆抗体及其制备方法和用途
CN110357961B (zh) * 2018-04-10 2022-08-23 无锡智康弘义生物科技有限公司 抗人4-1bb单克隆抗体及其制备方法和用途
US12054554B2 (en) 2018-04-10 2024-08-06 Wuxi Biologics (Shanghai) Co., Ltd. Monoclonal antibody against human 4-1BB, method for preparing the same, and use thereof

Also Published As

Publication number Publication date
ZA200602834B (en) 2007-07-25
TWI332844B (en) 2010-11-11
AR046094A1 (es) 2005-11-23
CN1867585A (zh) 2006-11-22
CN1867585B (zh) 2011-02-09
TW200517124A (en) 2005-06-01

Similar Documents

Publication Publication Date Title
PE20050962A1 (es) Anticuerpos completamente humanos contra 4-1bb humano
AR075790A2 (es) Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)
CO6220978A2 (es) Anticuerpos dirigidos a proteina-1 quimio-tactica de monocitos (mcp-1)y sus usos
PE20140231A1 (es) Proteinas de union a antigeno contra proproteina converstasa subtilisina/kexina tipo 9 (pcsk9)
AR033978A1 (es) Molecula de anticuerpo con especificidad para factor de necrosis tumoral alfa humano y usos de las mismas
PE20120429A1 (es) Proteinas de enlace de miostatina
CY1123978T1 (el) Σταθερα και διαλυτα αντισωματα που αναστελλουν ton tnf
ES2572177T3 (es) Anticuerpos neutralizantes anti-B7RP1 humanos
PE20070374A1 (es) ANTICUERPOS ANTI-MAdCAM
AR113225A2 (es) Anticuerpo monoclonal aislado que se une específicamente a cxcr4 humano expresado sobre la superficie de una célula y que es capaz de inducir apoptosis de célula tumorales cxcr4⁺ in vivo
AR086511A2 (es) Agentes de union especifica al factor de crecimiento de hepatocitos
CY1118443T1 (el) Anti-tnf αντισωματα, συνθεσεις, μεθοδοι και χρησεις
PE20050712A1 (es) Anticuerpos rg1
CY1114855T1 (el) Αντισωματα και μορια που προερχονται απο αυτα που δεσμευονται στις πρωτεϊνες toy steap-1
PE20080035A1 (es) Anticuerpos monoclonales humanos para la quinasa-1 tipo receptor de activina
PE20060817A1 (es) Anticuerpos anti-5t4 humanizados y conjugados anticuerpo anti-5t4/calicheamicina
PE20120014A1 (es) Anticuerpos humanos de alta afinidad contra pcsk9
PE20220708A1 (es) Anticuerpos anti-cd73
PE20141151A1 (es) Proteinas de union al antigeno cd27l
PE20130643A1 (es) Conjugados de anticuerpos multifuncionales
CY1107628T1 (el) Ανθρωπινα ctla-4 αντισωματα και χρησεις αυτων
PE20241623A1 (es) Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y usos de los mismos
CO6231038A2 (es) Proteinas de union, incluyendo anticuerpos derivados de anticuerpo y fragmentos de anticuerpo que se unen especificamente a cd154 y sus usos
PE20061115A1 (es) Anticuerpos anti-il-12, epitopos, composiciones, metodos y usos
EE200700052A (et) Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu

Legal Events

Date Code Title Description
FG Grant, registration