CN1867585B - 抗人4-1bb(cd137)的完全人抗体 - Google Patents

抗人4-1bb(cd137)的完全人抗体 Download PDF

Info

Publication number: CN1867585B
Authority: CN; China
Prior art keywords: cells; ser; human; seq; leu
Prior art date: 2003-10-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CN2004800297756A

Other languages

English (en)

Chinese (zh)

Other versions

CN1867585A (zh

Inventor

玛丽亚·朱尔-孔克尔

劳拉·J·赫夫塔

马克·桑托罗

苏比内伊·甘古利

爱德华·L·哈尔克

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-10

Filing date

2004-10-12

Publication date

2011-02-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37426115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1867585(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-10-08 Priority claimed from US10/961,567 external-priority patent/US7288638B2/en

2004-10-12 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2006-11-22 Publication of CN1867585A publication Critical patent/CN1867585A/zh

2011-02-09 Application granted granted Critical

2011-02-09 Publication of CN1867585B publication Critical patent/CN1867585B/zh

2024-10-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

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Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CN2004800297756A 2003-10-10 2004-10-12 抗人4-1bb(cd137)的完全人抗体 Expired - Fee Related CN1867585B (zh)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US51019303P	2003-10-10	2003-10-10
US60/510,193		2003-10-10
US10/961,567		2004-10-08
US10/961,567 US7288638B2 (en)	2003-10-10	2004-10-08	Fully human antibodies against human 4-1BB
PCT/US2004/033587 WO2005035584A1 (en)	2003-10-10	2004-10-12	Fully human antibodies against human 4-1bb (cd137)

Publications (2)

Publication Number	Publication Date
CN1867585A CN1867585A (zh)	2006-11-22
CN1867585B true CN1867585B (zh)	2011-02-09

Family

ID=37426115

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN2004800297756A Expired - Fee Related CN1867585B (zh)	2003-10-10	2004-10-12	抗人4-1bb(cd137)的完全人抗体

Country Status (5)

Country	Link
CN (1)	CN1867585B (es)
AR (1)	AR046094A1 (es)
PE (1)	PE20050962A1 (es)
TW (1)	TWI332844B (es)
ZA (1)	ZA200602834B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US11242395B2 (en) *	2017-08-21	2022-02-08	Adagene Inc.	Anti-CD137 molecules and use thereof
US11952681B2 (en)	2018-02-02	2024-04-09	Adagene Inc.	Masked activatable CD137 antibodies

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2810359C (en) *	2010-09-09	2021-06-22	Pfizer Inc.	4-1bb binding molecules
KR101503341B1 (ko)	2014-03-12	2015-03-18	국립암센터	자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법
RU2017142008A (ru) *	2015-05-21	2019-06-24	Эллигейтор Биосайенс Аб	Новые полипептиды
EP3354661B1 (en)	2015-09-22	2020-06-03	Dingfu Biotarget Co., Ltd.	Fully human antibody against human cd137 and use thereof
GB201619648D0 (en) *	2016-11-21	2017-01-04	Alligator Bioscience Ab	Novel antibodies and uses thereof
CA3039772C (en)	2017-01-06	2020-08-25	Eutilex Co., Ltd.	Anti-human 4-1bb antibodies and uses thereof
US11987635B2 (en) *	2017-06-25	2024-05-21	Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.	Anti-4-1BB antibodies and methods of making and using thereof
JP7402521B2 (ja) *	2017-07-11	2023-12-21	コンパスセラピューティクスリミテッドライアビリティカンパニー	ヒトｃｄ１３７に結合するアゴニスト性抗体およびその使用
WO2019072274A1 (zh) *	2017-10-12	2019-04-18	瑞阳(苏州)生物科技有限公司	一种激动型4-1bb单克隆抗体
CN109651507B (zh)	2017-10-12	2021-11-26	瑞阳(苏州)生物科技有限公司	一种激动型4-1bb单克隆抗体
TWI701259B (zh)	2017-11-09	2020-08-11	大陸商上海懷越生物科技有限公司	４﹘１ｂｂ抗體及其製備方法和應用
RU2020127196A (ru) *	2018-01-22	2022-02-24	Цзянсу Хэнжуй Медицин Ко., Лтд.	Антитело против 4-1bb, его антигенсвязывающий фрагмент и его медицинское применение
WO2019196868A1 (en)	2018-04-10	2019-10-17	Wuxi Biologics (Shanghai) Co., Ltd.	A monoclonal antibody against human 4-1bb, method for preparing the same, and use thereof
CN110357961B (zh) *	2018-04-10	2022-08-23	无锡智康弘义生物科技有限公司	抗人4-1bb单克隆抗体及其制备方法和用途
CN112867733B (zh) *	2018-10-19	2023-01-06	苏州丁孚靶点生物技术有限公司	抗cd137抗体及其应用
CN111320691B (zh) *	2018-12-17	2022-04-05	程联胜	一种抗人4-1bb单克隆抗体及其应用
CN112010974B (zh) *	2019-05-30	2022-08-09	山东博安生物技术股份有限公司	一种特异性结合人4-1bb的抗体及其应用
CN113842456B (zh) *	2020-06-28	2022-07-26	上海齐鲁制药研究中心有限公司	一种抗人4-1bb的单克隆抗体制剂及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996029348A1 (en) *	1995-03-23	1996-09-26	Indiana University Foundation	Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
CN1232402A (zh) *	1996-10-11	1999-10-20	布里斯托尔-迈尔斯斯奎布公司	免疫调节的方法和组合物

2004
- 2004-10-07 AR ARP040103643A patent/AR046094A1/es active IP Right Grant
- 2004-10-08 TW TW093130653A patent/TWI332844B/zh not_active IP Right Cessation
- 2004-10-11 PE PE2004000974A patent/PE20050962A1/es active IP Right Grant
- 2004-10-12 CN CN2004800297756A patent/CN1867585B/zh not_active Expired - Fee Related
2006
- 2006-04-06 ZA ZA200602834A patent/ZA200602834B/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996029348A1 (en) *	1995-03-23	1996-09-26	Indiana University Foundation	Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
CN1232402A (zh) *	1996-10-11	1999-10-20	布里斯托尔-迈尔斯斯奎布公司	免疫调节的方法和组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Deryk T.Loo et al."Analysis of 4-1BBL and laminin binding to murine 4-1BB, amember of the tumor necrosis factor receptor superfamily,and comparison with human 4-1BB.The Journal of Biological chemistry272 10.1997,272(10),6448-6456.
Deryk T.Loo et al."Analysis of 4-1BBL and laminin binding to murine 4-1BB, amember of the tumor necrosis factor receptor superfamily,and comparison with human 4-1BB.The Journal of Biological chemistry272 10.1997,272(10),6448-6456. *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US11242395B2 (en) *	2017-08-21	2022-02-08	Adagene Inc.	Anti-CD137 molecules and use thereof
US12378319B2 (en) *	2017-08-21	2025-08-05	Adagene Inc.	Anti-CD137 molecules and use thereof
US11952681B2 (en)	2018-02-02	2024-04-09	Adagene Inc.	Masked activatable CD137 antibodies

Also Published As

Publication number	Publication date
ZA200602834B (en)	2007-07-25
TWI332844B (en)	2010-11-11
AR046094A1 (es)	2005-11-23
PE20050962A1 (es)	2005-11-17
CN1867585A (zh)	2006-11-22
TW200517124A (en)	2005-06-01

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CN1867585B (zh)	2011-02-09	抗人4-1bb(cd137)的完全人抗体
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KR20220050948A (ko)	2022-04-25	입양 세포 치료요법을 위한 면역 세포
JP2008535868A (ja)	2008-09-04	免疫調節組成物およびそのための使用
JP2007516694A (ja)	2007-06-28	変異体ｌｉｇｈｔによるｔ細胞腫瘍浸潤の増大
KR102914114B1 (ko)	2026-01-20	Steap1에 대한 키메라 수용체 및 이의 사용 방법
KR20260017491A (ko)	2026-02-05	Steap1에 대한 키메라 수용체 및 이의 사용 방법
JP2025529256A (ja)	2025-09-04	ゲノム工学遺伝子療法においてＣａｓヌクレアーゼの免疫寛容を促進するためのペプチドコンジュゲートおよびその使用
HK40006441B (zh)	2021-10-15	嵌合受体及其方法和用途

Legal Events

Date	Code	Title	Description
2006-11-22	C06	Publication
2006-11-22	PB01	Publication
2007-01-17	C10	Entry into substantive examination
2007-01-17	SE01	Entry into force of request for substantive examination
2011-02-09	C14	Grant of patent or utility model
2011-02-09	GR01	Patent grant
2024-10-08	CF01	Termination of patent right due to non-payment of annual fee
2024-10-08	CF01	Termination of patent right due to non-payment of annual fee	Granted publication date: 20110209