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AR075790A2 - Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural) - Google Patents

Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)

Info

Publication number
AR075790A2
AR075790A2 ARP100100652A ARP100100652A AR075790A2 AR 075790 A2 AR075790 A2 AR 075790A2 AR P100100652 A ARP100100652 A AR P100100652A AR P100100652 A ARP100100652 A AR P100100652A AR 075790 A2 AR075790 A2 AR 075790A2
Authority
AR
Argentina
Prior art keywords
ngf
humans
growth factor
selective inhibitors
neural growth
Prior art date
Application number
ARP100100652A
Other languages
English (en)
Inventor
Heather Inoue
Haichun Huang
Kenneth D Wild Jr
Frank Martin
James J S Treanor
Tie J Zhang
Original Assignee
Amgen Inc
Medarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Medarex Inc filed Critical Amgen Inc
Publication of AR075790A2 publication Critical patent/AR075790A2/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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Abstract

Un anticuerpo humano aislado que se une específicamente a NGF, donde el anticuerpo comprende una cadena pesada con una region variable de cadena pesada y una region variable de cadena ligera donde la una region variable de cadena pesada comprende una secuencia de aminoácido con al menos 80% de identidad de secuencia a la secuencia de aminoácido establecida en SEQ ID Ns: 10, o un antígeno de union o un fragmento de inmunoglobulina funcional inmunologicamente del mismo.
ARP100100652A 2003-07-15 2010-03-04 Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural) AR075790A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48743103P 2003-07-15 2003-07-15

Publications (1)

Publication Number Publication Date
AR075790A2 true AR075790A2 (es) 2011-04-27

Family

ID=34215825

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP040102501A AR045056A1 (es) 2003-07-15 2004-07-15 Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf
ARP100100652A AR075790A2 (es) 2003-07-15 2010-03-04 Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)

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Application Number Title Priority Date Filing Date
ARP040102501A AR045056A1 (es) 2003-07-15 2004-07-15 Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf

Country Status (30)

Country Link
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