PE20021082A1 - Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologia - Google Patents
Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologiaInfo
- Publication number
- PE20021082A1 PE20021082A1 PE2002000306A PE2002000306A PE20021082A1 PE 20021082 A1 PE20021082 A1 PE 20021082A1 PE 2002000306 A PE2002000306 A PE 2002000306A PE 2002000306 A PE2002000306 A PE 2002000306A PE 20021082 A1 PE20021082 A1 PE 20021082A1
- Authority
- PE
- Peru
- Prior art keywords
- pharmaceutical composition
- macrolid
- ophthalmology
- local application
- based pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003981 vehicle Substances 0.000 abstract 3
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 abstract 2
- 239000010685 fatty oil Substances 0.000 abstract 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 abstract 2
- 150000003626 triacylglycerols Chemical class 0.000 abstract 2
- 235000013311 vegetables Nutrition 0.000 abstract 2
- -1 C12 FATTY ACIDS Chemical class 0.000 abstract 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 abstract 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 abstract 1
- 208000001860 Eye Infections Diseases 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 208000011323 eye infectious disease Diseases 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960002446 octanoic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA EN FORMA DE COLIRIO QUE COMPRENDE: a) UN ANTIBIOTICO MACROLIDO EN PARTICULAR AZALIDOS COMO AZITROMICINA Y b) UN VEHICULO OLEOSO O ACEITE GRASO DE ORIGEN VEGETAL, TRIGLICERIDOS DE ACIDOS CARBOXILICOS DE CADENA LINEAL DE C5-C12, SIENDO EL VEHICULO UN ACEITE GRASO DE ORIGEN VEGETAL COMPUESTO DE TRIGLICERIDOS ESENCIALMENTE ACIDOS GRASOS C5 A C12 COMO ACIDO CAPRILICO, ACIDO CAPRICO. EL VEHICULO OLEOSO PRESENTA UNA VISCOSIDAD ENTRE 10 mPa.s A 100 mPa.s, UNA DENSIDAD ENTRE 0.9 A 1 Y UN INDICE DE REFRACCION ENTRE 1 Y 2. LA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE INFECCIONES OCULARES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0105114A FR2823441B1 (fr) | 2001-04-12 | 2001-04-12 | Composition pharmaceutique a base de macrolides pour application locale en ophtalmologie et son procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20021082A1 true PE20021082A1 (es) | 2002-12-18 |
Family
ID=8862340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002000306A PE20021082A1 (es) | 2001-04-12 | 2002-04-11 | Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologia |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7064109B2 (es) |
| EP (1) | EP1377316B1 (es) |
| JP (2) | JP4558275B2 (es) |
| KR (1) | KR100835002B1 (es) |
| CN (1) | CN1496270B (es) |
| AR (1) | AR034033A1 (es) |
| AT (1) | ATE397460T1 (es) |
| BR (1) | BRPI0208367B8 (es) |
| CA (1) | CA2443728C (es) |
| CY (1) | CY1108302T1 (es) |
| CZ (1) | CZ300213B6 (es) |
| DE (1) | DE60226962D1 (es) |
| DK (1) | DK1377316T3 (es) |
| EA (1) | EA008088B1 (es) |
| EG (1) | EG23169A (es) |
| ES (1) | ES2307754T3 (es) |
| FR (1) | FR2823441B1 (es) |
| HR (1) | HRP20030907B1 (es) |
| HU (1) | HU230459B1 (es) |
| MA (1) | MA27005A1 (es) |
| MX (1) | MXPA03009349A (es) |
| OA (1) | OA12462A (es) |
| PA (1) | PA8543401A1 (es) |
| PE (1) | PE20021082A1 (es) |
| PL (1) | PL204403B1 (es) |
| PT (1) | PT1377316E (es) |
| SI (1) | SI1377316T1 (es) |
| TN (1) | TNSN03091A1 (es) |
| WO (1) | WO2002083178A1 (es) |
| ZA (1) | ZA200307718B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
| FR2884716B1 (fr) * | 2005-04-22 | 2009-08-21 | Thea Sa Lab | Utilisation de l'azithromycine pour la fabrication d'un medicament destine au traitement des infections oculaires |
| JPWO2007074904A1 (ja) * | 2005-12-28 | 2009-06-04 | わかもと製薬株式会社 | 水性医薬組成物 |
| BRPI0808410A2 (pt) * | 2007-02-28 | 2015-06-23 | Aciex Therapeutics Inc | Métodos e composições para normalizar secreções da glândula meibomiana |
| US20100158821A1 (en) * | 2008-12-22 | 2010-06-24 | Eastman Chemical Company | Antimicrobial agents, compositions and products containing the same, and methods of using the compositions and products |
| CN101780105B (zh) * | 2009-01-20 | 2011-09-28 | 沈阳兴齐制药有限公司 | 小牛血去蛋白提取物的滴眼液 |
| EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
| US8106111B2 (en) * | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
| EP2389939A1 (en) | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
| EP2394636B1 (en) * | 2010-05-28 | 2014-03-19 | Novagali Pharma S.A. | Method for treating retinal conditions using an intraocular tamponade |
| US9044508B2 (en) * | 2013-03-15 | 2015-06-02 | Insite Vision Corporation | Concentrated aqueous azalide formulations |
| EP3478269A4 (en) * | 2016-06-29 | 2020-04-08 | Otonomy, Inc. | OTIC FORMULATIONS BASED ON TRIGLYCERIDES AND THEIR USES |
| JOP20170147B1 (ar) * | 2016-07-07 | 2021-08-17 | Salvat Lab Sa | تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة |
| CN115475248A (zh) * | 2021-06-16 | 2022-12-16 | 云南拜奥泰克生物技术有限责任公司 | 一种新型药用甘油三酯溶剂及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1152644A (en) * | 1966-07-01 | 1969-05-21 | Abbott Lab | Stable Solutions of Erythromycin Free Base |
| JPS6468328A (en) * | 1987-09-09 | 1989-03-14 | Suntory Ltd | Anticorneoulcerative |
| JP2563336B2 (ja) * | 1987-06-01 | 1996-12-11 | エーザイ株式会社 | 角膜透過促進点眼剤 |
| FR2746035B1 (fr) * | 1996-03-15 | 1998-06-12 | Microparticules de gel composite susceptibles d'etre utilisees comme vecteur(s) de principe(s) actif(s), l'un de leurs procedes de preparation et leurs applications | |
| ES2221127T5 (es) * | 1997-12-02 | 2009-11-10 | Pfizer Products Inc. | Uso de acitromicina en el tratamiento topico de infecciones oculares. |
| JP2000159659A (ja) * | 1998-11-30 | 2000-06-13 | Kazuo Tsubota | 眼科用人工涙液 |
| US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
-
2001
- 2001-04-12 FR FR0105114A patent/FR2823441B1/fr not_active Expired - Lifetime
-
2002
- 2002-04-09 PA PA20028543401A patent/PA8543401A1/es unknown
- 2002-04-10 EG EG20020380A patent/EG23169A/xx active
- 2002-04-10 AR ARP020101319A patent/AR034033A1/es not_active Application Discontinuation
- 2002-04-11 US US10/474,811 patent/US7064109B2/en not_active Expired - Lifetime
- 2002-04-11 PT PT02732804T patent/PT1377316E/pt unknown
- 2002-04-11 TN TNPCT/FR2002/001263A patent/TNSN03091A1/fr unknown
- 2002-04-11 JP JP2002580979A patent/JP4558275B2/ja not_active Expired - Lifetime
- 2002-04-11 CZ CZ20032771A patent/CZ300213B6/cs not_active IP Right Cessation
- 2002-04-11 CA CA2443728A patent/CA2443728C/fr not_active Expired - Lifetime
- 2002-04-11 EP EP02732804A patent/EP1377316B1/fr not_active Expired - Lifetime
- 2002-04-11 HU HU0303864A patent/HU230459B1/hu unknown
- 2002-04-11 DE DE60226962T patent/DE60226962D1/de not_active Expired - Lifetime
- 2002-04-11 BR BRPI0208367A patent/BRPI0208367B8/pt not_active IP Right Cessation
- 2002-04-11 PE PE2002000306A patent/PE20021082A1/es not_active Application Discontinuation
- 2002-04-11 EA EA200301108A patent/EA008088B1/ru not_active IP Right Cessation
- 2002-04-11 AT AT02732804T patent/ATE397460T1/de active
- 2002-04-11 SI SI200230723T patent/SI1377316T1/sl unknown
- 2002-04-11 WO PCT/FR2002/001263 patent/WO2002083178A1/fr not_active Ceased
- 2002-04-11 MX MXPA03009349A patent/MXPA03009349A/es active IP Right Grant
- 2002-04-11 HR HR20030907A patent/HRP20030907B1/xx not_active IP Right Cessation
- 2002-04-11 DK DK02732804T patent/DK1377316T3/da active
- 2002-04-11 OA OA1200300246A patent/OA12462A/fr unknown
- 2002-04-11 KR KR1020037012372A patent/KR100835002B1/ko not_active Expired - Lifetime
- 2002-04-11 CN CN02806447XA patent/CN1496270B/zh not_active Expired - Lifetime
- 2002-04-11 PL PL363538A patent/PL204403B1/pl unknown
- 2002-04-11 ES ES02732804T patent/ES2307754T3/es not_active Expired - Lifetime
-
2003
- 2003-09-26 MA MA27325A patent/MA27005A1/fr unknown
- 2003-10-02 ZA ZA200307718A patent/ZA200307718B/en unknown
-
2008
- 2008-08-28 CY CY20081100927T patent/CY1108302T1/el unknown
-
2009
- 2009-10-08 JP JP2009234250A patent/JP5170780B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |