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AR049009A1 - Gel - crema que contiene ivermectina - Google Patents

Gel - crema que contiene ivermectina

Info

Publication number
AR049009A1
AR049009A1 ARP050101014A ARP050101014A AR049009A1 AR 049009 A1 AR049009 A1 AR 049009A1 AR P050101014 A ARP050101014 A AR P050101014A AR P050101014 A ARP050101014 A AR P050101014A AR 049009 A1 AR049009 A1 AR 049009A1
Authority
AR
Argentina
Prior art keywords
gel
ivermectine
melting point
cream containing
oily phase
Prior art date
Application number
ARP050101014A
Other languages
English (en)
Inventor
Fanny Astruc
Sandrine Orsoni
Laurent Fredon
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of AR049009A1 publication Critical patent/AR049009A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composicion farmacéutica a base de un compuesto de la familia de las avermectinas, en forma de un gel-crema, que comprende en un medio fisiologicamente aceptable, una fase aceitosa dispersada en una fase acuosa para un emulsionante polimérico no tensioactivo, y dicha fase aceitosa comprende aceites que tienen un punto de fusion inferior a 30sC y está exenta de cuerpos grasos solidos que tengan un punto de fusion superior a 30sC. Procedimiento de preparacion y utilizacion en la fabricacion de una preparacion farmacéutica destinada al tratamiento de las afecciones dermatologicas, rosácea, entre otras.
ARP050101014A 2004-03-18 2005-03-16 Gel - crema que contiene ivermectina AR049009A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0402798A FR2867684B1 (fr) 2004-03-18 2004-03-18 Gel creme contenant de l'ivermectine

Publications (1)

Publication Number Publication Date
AR049009A1 true AR049009A1 (es) 2006-06-21

Family

ID=34896615

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050101014A AR049009A1 (es) 2004-03-18 2005-03-16 Gel - crema que contiene ivermectina

Country Status (14)

Country Link
EP (1) EP1729811B1 (es)
JP (1) JP5248853B2 (es)
KR (1) KR101278806B1 (es)
CN (1) CN1933856B (es)
AR (1) AR049009A1 (es)
AT (1) ATE465758T1 (es)
AU (1) AU2005224038B2 (es)
BR (1) BRPI0508167A (es)
CA (1) CA2558254C (es)
ES (1) ES2345664T3 (es)
FR (1) FR2867684B1 (es)
RU (1) RU2389494C2 (es)
WO (1) WO2005089806A1 (es)
ZA (1) ZA200606667B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2854074B1 (fr) 2003-04-24 2007-11-23 Galderma Res & Dev Utilisation de l'ivermectine pour le traitement de desordres dermatologiques
BRPI0410503B8 (pt) 2003-04-24 2021-05-25 Galderma Sa composição tópica e uso da composição
CA2620814A1 (en) * 2005-09-30 2007-05-18 Galderma S.A. Use of at least one compound of the family of the avermectins or of the family of the milbemycins in the treatment of ophthalmic pathologies
FR2894823B1 (fr) 2005-12-20 2008-02-29 Galderma Sa Composition de type emulsion inverse comprenant de l'ivermectine, et ses utilisations en cosmetique et en dermatologie
FR2900052B1 (fr) 2006-04-19 2011-02-18 Galderma Sa Composition comprenant au moins une phase aqueuse et au moins une phase grasse comprenant de l'ivermectine
FR2903002B1 (fr) * 2006-07-03 2012-08-17 Oreal Composition associant un derive c-glycoside et un polymere emulsionnant
FR2902999B1 (fr) 2006-07-03 2012-09-28 Oreal Utilisation de derives c-glycoside a titre d'actif prodesquamant
FR2906466B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des milbemycines pour le traitement de desordres dermatologiques chez l'homme
FR2906469B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques chez l'homme
FR2906467B1 (fr) * 2006-09-28 2012-11-09 Galderma Sa Utilisation de composes de la famille des milbemycines pour le traitement de desordres dermatologiques chez l'homme
FR2906465B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques chez l'homme
FR2906468B1 (fr) * 2006-09-28 2012-09-21 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques
EP2453003B1 (en) * 2006-12-15 2017-05-03 Colgate-Palmolive Company Liquid Detergent Composition
US8901163B2 (en) * 2007-01-03 2014-12-02 Galderma S.A. Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or plants using avermectin compound
FR2937972B1 (fr) 2008-11-04 2013-03-29 Galderma Res & Dev Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
TW201041508A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
CN103356687B (zh) * 2012-10-19 2016-06-01 厦门大学 一种伊维菌素及其衍生物的用途
RU2530644C2 (ru) * 2012-11-01 2014-10-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Противоугревая фармацевтическая композиция и способ ее получения
FR3002444B1 (fr) * 2013-02-25 2015-03-13 Oreal Composition cosmetique de type gel
FR3002448B1 (fr) * 2013-02-25 2015-04-03 Oreal Composition cosmetique de type gel
US9782425B2 (en) 2013-07-08 2017-10-10 Galderma S.A. Treatment of papulopustular rosacea with ivermectin
US9233117B2 (en) * 2013-07-08 2016-01-12 Galderma S. A. Treatment of inflammatory lesions of rosacea with ivermectin
JP6448641B2 (ja) * 2013-11-29 2019-01-09 ガルデルマ・ソシエテ・アノニム アトピー性皮膚炎の治療及び／又は予防のためのアベルメクチンファミリー又はミルベマイシンファミリーの化合物
WO2015109312A1 (en) 2014-01-20 2015-07-23 Merial Inc. Topical delivery formulation
US10849854B2 (en) 2015-10-13 2020-12-01 Galderma S.A. Process for preparing a composition comprising a high concentration of one or more avermectins
JP6901472B2 (ja) 2015-10-13 2021-07-14 ガルデルマ エス．エー． １種又は複数のアベルメクチンを含む安定したエマルションを調製する方法
EP4062907A1 (fr) 2021-03-23 2022-09-28 Substipharm Formulation par voie orale d'ivermectine et utilisations
CN116421560A (zh) * 2023-05-26 2023-07-14 山东中牧兽药有限公司 一种阿苯达唑伊维菌素的微乳剂及其制备方法
CN120037250A (zh) * 2025-04-07 2025-05-27 江苏知原药业股份有限公司 一种伊维菌素外用药物组合物、制备方法及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880005918A (ko) * 1986-11-10 1988-07-21 원본미기재 안정하며 빨리 분해되는 국소피부조성물
US5474979A (en) * 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
US5952372A (en) * 1998-09-17 1999-09-14 Mcdaniel; William Robert Method for treating rosacea using oral or topical ivermectin
MXPA01007486A (es) * 1999-01-25 2003-06-24 Optime Therapeutics Inc Formulaciones de liposomas.
CN1237337A (zh) * 1999-05-26 1999-12-08 解俊峰 阿维菌素、伊维菌素微乳剂
US6133310A (en) * 1999-08-26 2000-10-17 Parks; L. Dean Method of treatment of rosacea
RU2149007C1 (ru) * 1999-09-28 2000-05-20 Закрытое акционерное общество "Агроветсервис" Антипаразитарная, антимикробная противовоспалительная мазь пролонгированного действия
US6319945B1 (en) * 2000-06-29 2001-11-20 L. Dean Parks Method of treatment of seborrheic dermatitis
US6399651B1 (en) * 2000-06-29 2002-06-04 L. Dean Parks Method of treating dermatoses using avermectin compound
US6399652B1 (en) * 2000-06-29 2002-06-04 L. Dean Parks Method of treating acne vulgaris using avermectin compound
CA2473760C (en) * 2002-02-08 2008-11-04 Merck & Co., Inc. Topical ivermectin composition
BRPI0410503B8 (pt) * 2003-04-24 2021-05-25 Galderma Sa composição tópica e uso da composição
FR2854074B1 (fr) * 2003-04-24 2007-11-23 Galderma Res & Dev Utilisation de l'ivermectine pour le traitement de desordres dermatologiques

Also Published As

Publication number Publication date
BRPI0508167A (pt) 2007-08-07
EP1729811B1 (en) 2010-04-28
ATE465758T1 (de) 2010-05-15
KR20070001148A (ko) 2007-01-03
ZA200606667B (en) 2007-10-31
KR101278806B1 (ko) 2013-06-25
FR2867684B1 (fr) 2006-05-05
JP5248853B2 (ja) 2013-07-31
CN1933856B (zh) 2010-12-08
CN1933856A (zh) 2007-03-21
RU2006136805A (ru) 2008-04-27
WO2005089806A1 (en) 2005-09-29
AU2005224038B2 (en) 2011-06-23
CA2558254A1 (en) 2005-09-29
CA2558254C (en) 2013-01-15
EP1729811A1 (en) 2006-12-13
JP2007529465A (ja) 2007-10-25
FR2867684A1 (fr) 2005-09-23
AU2005224038A1 (en) 2005-09-29
ES2345664T3 (es) 2010-09-29
RU2389494C2 (ru) 2010-05-20

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