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PE20020421A1 - Produccion de terpenoides ciclicos - Google Patents

Produccion de terpenoides ciclicos

Info

Publication number
PE20020421A1
PE20020421A1 PE2001000881A PE2001000881A PE20020421A1 PE 20020421 A1 PE20020421 A1 PE 20020421A1 PE 2001000881 A PE2001000881 A PE 2001000881A PE 2001000881 A PE2001000881 A PE 2001000881A PE 20020421 A1 PE20020421 A1 PE 20020421A1
Authority
PE
Peru
Prior art keywords
methylobacter
encoding gene
production
cyclic
substrate
Prior art date
Application number
PE2001000881A
Other languages
English (en)
Inventor
Deana J Dicosimo
Mattheos Koffas
Siqun Wang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of PE20020421A1 publication Critical patent/PE20020421A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/30Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UN METODO PARA LA PRODUCCION DE TERPENOS CICLICO A PARTIR DE GERANIL PIROFOSFATO EN UN HUESPED MICROBIANO METILOTROPICO O METANOTROPICO TRANSFORMADO COMO METHYLOMONAS 16a (ATTC PTA 2402), METHYLOBACTER, METHYLOCOCCUS, METHYLOSINUS, METHYLOCICTIS, METHYLOMICROBIUM, METHAMONAS, METHYLOPHILUS; QUE UTILIZAN LA VIA ISOPRENOIDE SIENDO EL SUSTRATO METANO, METANOL, FORMALDEHIDO, ACIDO FORMICO, AMINAS METILADAS, TIOLES METILADOS, DIOXIDO DE CARBONO; LA VIA EMBDEN MEYERHOF; VIA ENTNER DOUDEROFF Y ADEMAS CONTIENEN UN GEN CODIFICADOR DE TERPENO CICLICO SINTASA COMO SINTASA DE LIMONENO, PINENO, BORNIL, PELANDRENO, CINEOLE, SABINENO; BAJO EL CONTROL DE SECUENCIAS REGULADORAS; O UN GEN CODIFICADOR DE LA ENZIMA BISFOSFATO FRUCTOSA ALDOLASA; CETODEOXI FOSFOGLUCONATO ALDOLASA; MANTENIENDO A LAS CELULAS HUESPED EN CONDICIONES DE DESARROLLO CON UN SUSTRATO DE CARBONO. LOS MONOTERPENOS PROPORCIONAN SABOR Y FRAGANCIA Y SE UTILIZAN COMO COMPONENTES EN DISOLVENTES INDUSTRIALES SIENDO OBTENIDOS POR FUENTES NATURALES O SINTESIS QUIMICA, AMBOS PROCEDIMIENTOS CONSUMEN TIEMPO Y SON COSTOSOS
PE2001000881A 2000-09-01 2001-09-03 Produccion de terpenoides ciclicos PE20020421A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22990700P 2000-09-01 2000-09-01
US22985800P 2000-09-01 2000-09-01

Publications (1)

Publication Number Publication Date
PE20020421A1 true PE20020421A1 (es) 2002-06-25

Family

ID=26923677

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000881A PE20020421A1 (es) 2000-09-01 2001-09-03 Produccion de terpenoides ciclicos

Country Status (11)

Country Link
US (2) US6818424B2 (es)
EP (2) EP1313841A2 (es)
JP (2) JP2005500805A (es)
KR (1) KR20030034160A (es)
AU (2) AU2001288477A1 (es)
CA (2) CA2417246A1 (es)
IL (1) IL154090A0 (es)
MX (1) MXPA03001822A (es)
NO (2) NO20030343L (es)
PE (1) PE20020421A1 (es)
WO (2) WO2002020815A2 (es)

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WO2002079395A2 (en) 2001-01-26 2002-10-10 Cargill, Incorporated Carotenoid biosynthesis

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US6969595B2 (en) 2005-11-29
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