PE20001375A1 - Metodo para producir acido l-glutamico por fermentacion - Google Patents
Metodo para producir acido l-glutamico por fermentacionInfo
- Publication number
- PE20001375A1 PE20001375A1 PE1999001285A PE00128599A PE20001375A1 PE 20001375 A1 PE20001375 A1 PE 20001375A1 PE 1999001285 A PE1999001285 A PE 1999001285A PE 00128599 A PE00128599 A PE 00128599A PE 20001375 A1 PE20001375 A1 PE 20001375A1
- Authority
- PE
- Peru
- Prior art keywords
- glutamic acid
- fermentation
- produce
- pyruvate dehydrogenase
- producing ability
- Prior art date
Links
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 title abstract 12
- 229960002989 glutamic acid Drugs 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title 1
- 230000004151 fermentation Effects 0.000 title 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 abstract 2
- 230000003834 intracellular effect Effects 0.000 abstract 2
- 229930003451 Vitamin B1 Natural products 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 241000186254 coryneform bacterium Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960003495 thiamine Drugs 0.000 abstract 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract 1
- 239000011691 vitamin B1 Substances 0.000 abstract 1
- 235000010374 vitamin B1 Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N3/00—Spore forming or isolating processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
SE REFIERE A UNA BACTERIA CORINEFORME CON CAPACIDAD PARA PRODUCIR ACIDO L-GLUTAMICO QUE TIENE ACTIVIDAD INTRACELULAR AUMENTADA DE LA PIRUVATO DESHIDROGENASA OBTENIDA POR EL AUMENTO DE LAS REPLICAS DE UN GEN QUE CODIFICA LA PIRUVATO DESHIDROGENASA DERIVADO DE ESCHERICHIA COLI. TAMBIEN SE REFIERE A UN METODO PARA PRODUCIR ACIDO L-GLUTAMICO QUE COMPRENDE EL CULTIVO DE LAS BACTERIAS CORINEFORME EN UN MEDIO PARA PRODUCIR Y ACUMULAR ACIDO L-GLUTAMICO; EL MEDIO CONTIENE 20µg/L DE VITAMINA B1. TAMBIEN SE REFIERE A UN ADN QUE CODIFICA a)UNA PROTEINA QUE TIENE LA SECUENCIA DE AMINOACIDO DE LA SEQ ID NO 10 DE 922 AMINOACIDOS; b)UNA PROTEINA CON UNA SECUENCIA DE AMINOACIDO DE SEQ ID NO 10 INCLUYENDO SUSTITUCION, ELIMINACION, INSERCION, ADICION, INVERSION DE UNO O VARIOS AMINOACIDOS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36061998 | 1998-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20001375A1 true PE20001375A1 (es) | 2000-12-14 |
Family
ID=18470193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999001285A PE20001375A1 (es) | 1998-12-18 | 1999-12-17 | Metodo para producir acido l-glutamico por fermentacion |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1010755B1 (es) |
| CN (1) | CN100358999C (es) |
| AT (1) | ATE483792T1 (es) |
| BR (1) | BR9906279A (es) |
| DE (1) | DE69942821D1 (es) |
| ID (1) | ID24576A (es) |
| MY (1) | MY137515A (es) |
| PE (1) | PE20001375A1 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19956131A1 (de) * | 1999-11-23 | 2001-05-31 | Degussa | Neue für das pfk-Gen codierende Nukleotidsequenzen |
| WO2003076635A1 (en) * | 2002-03-13 | 2003-09-18 | Degussa Ag | Process for the preparation of l-amino acids using strains of the family enterobacteriaceae |
| AU2005320486B2 (en) | 2004-12-28 | 2009-08-13 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid |
| JP2009118740A (ja) | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| EP2192170B1 (en) | 2007-09-04 | 2017-02-15 | Ajinomoto Co., Inc. | Amino acid-producing microorganism and method of producing amino acid |
| JP5526785B2 (ja) | 2008-01-23 | 2014-06-18 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| PE20110369A1 (es) | 2008-09-08 | 2011-06-24 | Ajinomoto Kk | Un microorganismo que produce l-aminoacido y un metodo para producir un l-aminoacido |
| JPWO2011013707A1 (ja) | 2009-07-29 | 2013-01-10 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2013074795A (ja) | 2010-02-08 | 2013-04-25 | Ajinomoto Co Inc | 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法 |
| JP2014036576A (ja) | 2010-12-10 | 2014-02-27 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| WO2012157699A1 (ja) | 2011-05-18 | 2012-11-22 | 味の素株式会社 | 動物用免疫賦活剤、それを含む飼料及びその製造方法 |
| EP2778228B1 (en) | 2011-11-11 | 2017-05-17 | Ajinomoto Co., Inc. | Method for producing 2-ketoglutaric acid and derivatives thereof by using a bacterium from the genus pantoea or the genus corynebacterium |
| MY185322A (en) | 2013-05-13 | 2021-05-04 | Ajinomoto Kk | Method for producing l-amino acid |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのｌ−アミノ酸の製造方法 |
| WO2015060314A1 (ja) | 2013-10-21 | 2015-04-30 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
| KR102265924B1 (ko) | 2014-10-31 | 2021-06-15 | 삼성바이오에피스 주식회사 | Pdk 불활성화에 의한 폴리펩타이드의 생산 |
| KR101776375B1 (ko) * | 2015-03-18 | 2017-09-08 | 씨제이제일제당 (주) | 피루브산 디하이드로게나아제 변이체, 이를 포함하는 미생물 및 이를 이용한 l-아미노산 생산 방법 |
| JP6623690B2 (ja) | 2015-10-30 | 2019-12-25 | 味の素株式会社 | グルタミン酸系ｌ−アミノ酸の製造法 |
| JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| CN107974473B (zh) * | 2017-12-15 | 2020-06-19 | 内蒙古伊品生物科技有限公司 | 谷氨酸的发酵生产及后处理 |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| BR112021011882A2 (pt) | 2018-12-27 | 2021-09-08 | Ajinomoto Co., Inc. | Método para produzir um l-aminoácido básico |
| JP7491314B2 (ja) | 2019-02-22 | 2024-05-28 | 味の素株式会社 | ｙｄｉＪ遺伝子を過剰発現する腸内細菌科に属する細菌を用いたＬ－アミノ酸の製造方法 |
| JP7524909B2 (ja) | 2019-04-05 | 2024-07-30 | 味の素株式会社 | Ｌ－アミノ酸の製造方法 |
| JP7655312B2 (ja) | 2019-09-25 | 2025-04-02 | 味の素株式会社 | 細菌の発酵によるｌ－アミノ酸の製造方法 |
| JP7764852B2 (ja) | 2019-09-25 | 2025-11-06 | 味の素株式会社 | 細菌の発酵による２－メチル酪酸の製造方法 |
| PE20231508A1 (es) | 2020-10-28 | 2023-09-26 | Ajinomoto Kk | Metodo de produccion de l-aminoacido |
| US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
| WO2025141837A1 (ja) | 2023-12-28 | 2025-07-03 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
| JP7716823B1 (ja) | 2023-12-28 | 2025-08-01 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2520895B2 (ja) * | 1987-03-04 | 1996-07-31 | 旭化成工業株式会社 | Ｌ―グルタミン酸の製造方法 |
| EP0780477B1 (en) | 1994-08-19 | 2003-04-09 | Ajinomoto Co., Inc. | Process for producing l-lysine and l-glutamic acid by fermentation |
-
1999
- 1999-12-17 AT AT99125302T patent/ATE483792T1/de not_active IP Right Cessation
- 1999-12-17 EP EP99125302A patent/EP1010755B1/en not_active Expired - Lifetime
- 1999-12-17 BR BR9906279-8A patent/BR9906279A/pt not_active Application Discontinuation
- 1999-12-17 DE DE69942821T patent/DE69942821D1/de not_active Expired - Lifetime
- 1999-12-17 PE PE1999001285A patent/PE20001375A1/es not_active Application Discontinuation
- 1999-12-17 MY MYPI99005539A patent/MY137515A/en unknown
- 1999-12-18 CN CNB99122969XA patent/CN100358999C/zh not_active Expired - Fee Related
- 1999-12-20 ID IDP991158A patent/ID24576A/id unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN100358999C (zh) | 2008-01-02 |
| EP1010755A1 (en) | 2000-06-21 |
| ID24576A (id) | 2000-07-27 |
| BR9906279A (pt) | 2001-04-24 |
| ATE483792T1 (de) | 2010-10-15 |
| EP1010755B1 (en) | 2010-10-06 |
| MY137515A (en) | 2009-02-27 |
| DE69942821D1 (de) | 2010-11-18 |
| CN1270226A (zh) | 2000-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |