[go: up one dir, main page]

LV10253B - Indenoindole compounds ii - Google Patents

Indenoindole compounds ii

Info

Publication number
LV10253B
LV10253B LVP-93-568A LV930568A LV10253B LV 10253 B LV10253 B LV 10253B LV 930568 A LV930568 A LV 930568A LV 10253 B LV10253 B LV 10253B
Authority
LV
Latvia
Prior art keywords
lower alkyl
hydrogen
group
cor
alkyl group
Prior art date
Application number
LVP-93-568A
Other languages
English (en)
Other versions
LV10253A (lv
Inventor
Malcolm Sainsbury
Howard G Shertzer
Original Assignee
Univ Bath
Univ Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bath, Univ Cincinnati filed Critical Univ Bath
Publication of LV10253A publication Critical patent/LV10253A/xx
Publication of LV10253B publication Critical patent/LV10253B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
LVP-93-568A 1989-06-22 1993-06-14 Indenoindole compounds ii LV10253B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii
PCT/GB1990/000949 WO1990015799A1 (en) 1989-06-22 1990-06-20 Indenoindole compounds ii

Publications (2)

Publication Number Publication Date
LV10253A LV10253A (lv) 1994-10-20
LV10253B true LV10253B (en) 1995-04-20

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-568A LV10253B (en) 1989-06-22 1993-06-14 Indenoindole compounds ii

Country Status (34)

Country Link
EP (1) EP0409410B1 (el)
JP (1) JP3064411B2 (el)
KR (1) KR920702679A (el)
CN (1) CN1033029C (el)
AT (1) ATE135688T1 (el)
BG (1) BG60317B2 (el)
CA (1) CA2060897A1 (el)
DD (1) DD297960A5 (el)
DE (1) DE69025998T2 (el)
DK (1) DK0409410T3 (el)
DZ (1) DZ1428A1 (el)
ES (1) ES2084660T3 (el)
FI (1) FI100800B (el)
GR (1) GR3019779T3 (el)
HR (1) HRP920903B1 (el)
HU (1) HUT59097A (el)
IE (1) IE74682B1 (el)
IL (1) IL94830A (el)
IS (1) IS3590A7 (el)
LT (1) LT3675B (el)
LV (1) LV10253B (el)
MX (1) MX21244A (el)
MY (1) MY107311A (el)
NO (1) NO177932C (el)
NZ (1) NZ234175A (el)
PL (1) PL167761B1 (el)
PT (1) PT94468B (el)
RO (1) RO111573B1 (el)
RU (1) RU2104270C1 (el)
SE (1) SE8902274D0 (el)
SI (1) SI9011223B (el)
WO (1) WO1990015799A1 (el)
YU (1) YU122390A (el)
ZA (1) ZA904827B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU166291A (sh) * 1990-10-16 1994-04-05 University Of Bath Claverton Down Indenoindol jedinjenja
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
AU675141B2 (en) * 1993-07-20 1997-01-23 Adir Et Compagnie (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
AU2163600A (en) * 1998-12-04 2000-06-26 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2007009120A2 (en) 2005-07-14 2007-01-18 Irm Llc Heterotetracyclic compounds as tpo mimetics
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
CA3124852A1 (en) * 2011-06-16 2012-12-20 Korea Research Institute Of Chemical Technology Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
SI3882244T1 (sl) 2012-12-14 2025-07-31 Korea Research Institute Of Chemical Technology Spojina, farmacevtsko sprejemljiva sol ali optični izomer le-te, postopek za njeno pripravo in farmacevtski sestavek za preprečevanje ali zdravljenje virusnih bolezni, ki jo vsebuje kot učinkovino
CA3176618A1 (en) 2020-04-20 2021-10-28 Novartis Ag Antiviral 1,3-di-oxo-indene compounds
TWI832045B (zh) 2020-04-20 2024-02-11 瑞士商諾華公司 抗病毒性1,3-二氧代茚化合物

Also Published As

Publication number Publication date
CN1033029C (zh) 1996-10-16
LTIP912A (en) 1995-03-27
NO177932C (no) 1995-12-20
BG60317B2 (bg) 1994-07-25
HRP920903A2 (hr) 1994-04-30
PL285752A1 (en) 1991-03-11
IE902247L (en) 1990-12-22
CN1051554A (zh) 1991-05-22
DZ1428A1 (fr) 2004-09-13
HRP920903B1 (en) 1998-06-30
AU644084B2 (en) 1993-12-02
GR3019779T3 (en) 1996-07-31
YU122390A (sh) 1992-09-07
MY107311A (en) 1995-11-30
IL94830A (en) 1996-07-23
PT94468A (pt) 1991-02-08
WO1990015799A1 (en) 1990-12-27
EP0409410B1 (en) 1996-03-20
CA2060897A1 (en) 1990-12-23
DE69025998D1 (de) 1996-04-25
ZA904827B (en) 1991-04-24
DD297960A5 (de) 1992-01-30
FI100800B (fi) 1998-02-27
HU904825D0 (en) 1992-03-30
PL167761B1 (pl) 1995-10-31
SI9011223A (en) 1997-10-31
JP3064411B2 (ja) 2000-07-12
FI915999A0 (fi) 1991-12-19
IL94830A0 (en) 1991-04-15
NO915049L (no) 1992-02-21
LV10253A (lv) 1994-10-20
NZ234175A (en) 1992-12-23
IE902247A1 (en) 1991-01-16
EP0409410A1 (en) 1991-01-23
SI9011223B (sl) 1998-08-31
MX21244A (es) 1994-03-31
RU2104270C1 (ru) 1998-02-10
ES2084660T3 (es) 1996-05-16
DE69025998T2 (de) 1996-08-08
AU5836990A (en) 1991-01-08
SE8902274D0 (sv) 1989-06-22
PT94468B (pt) 1997-12-31
KR920702679A (ko) 1992-10-06
NO915049D0 (no) 1991-12-20
NO177932B (no) 1995-09-11
IS3590A7 (is) 1990-12-23
ATE135688T1 (de) 1996-04-15
LT3675B (en) 1996-01-25
JPH04505923A (ja) 1992-10-15
HUT59097A (en) 1992-04-28
DK0409410T3 (da) 1996-04-29
IE74682B1 (en) 1997-07-30
RO111573B1 (ro) 1996-11-29

Similar Documents

Publication Publication Date Title
ZA847650B (en) 1-methylamino-cyclopropane-1-carboxylic acid derivatives
EP0163599A3 (en) Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
ZA904827B (en) Indenoindole compounds ii
GR3004139T3 (el)
IE851205L (en) Beta-carbolines
HUT73437A (en) Novel pyrrolocarbazoles
SE8902273D0 (sv) Indenoindole compounds i
EP0161575A3 (en) B-carboline-3-carboxylic acid derivatives, method of preparing the same and their use
HUT47544A (en) Process for producing benzazepine-sulfonamides and antiarrhythmic agents comprising these compounds
ZA895623B (en) Tetracyclic antidepressants
JO1676B1 (en) Extra compounds indinol II
EP0470832A3 (en) Biphenyl 5, 5'-bis-alkanoic acid derivatives, their production and use thereof
DE3362523D1 (en) Optically active imidazolylpropanol compounds, and their production and use
AU4370489A (en) The use of oxidized polyamines, especially nn'-bis-(3- propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents
GB2021587A (en) Benzoquinolizines