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LTPA2007001I1 - Pakeistieji 3,5-difenil-1,2,4-triazolai ir jų panaudojimas farmaciniais metalų chelatoriais - Google Patents

Pakeistieji 3,5-difenil-1,2,4-triazolai ir jų panaudojimas farmaciniais metalų chelatoriais

Info

Publication number
LTPA2007001I1
LTPA2007001I1 LTPA2007001C LTPA2007001C LTPA2007001I1 LT PA2007001 I1 LTPA2007001 I1 LT PA2007001I1 LT PA2007001 C LTPA2007001 C LT PA2007001C LT PA2007001 C LTPA2007001 C LT PA2007001C LT PA2007001 I1 LTPA2007001 I1 LT PA2007001I1
Authority
LT
Lithuania
Prior art keywords
triazoles
diphenyl
modified
metal chelators
pharmaceutical metal
Prior art date
Application number
LTPA2007001C
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4214048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTPA2007001(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LTPA2007001I1 publication Critical patent/LTPA2007001I1/lt
Publication of LTC0914118I2 publication Critical patent/LTC0914118I2/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTPA2007001C 1996-06-25 2007-01-16 Pakeistieji 3,5-difenil-1,2,4-triazolai ir jų panaudojimas farmaciniais metalų chelatoriais LTC0914118I2 (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH159396 1996-06-25
PCT/EP1997/003315 WO1997049395A1 (en) 1996-06-25 1997-06-24 Substituted 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators

Publications (2)

Publication Number Publication Date
LTPA2007001I1 true LTPA2007001I1 (lt) 2018-06-25
LTC0914118I2 LTC0914118I2 (lt) 2018-12-27

Family

ID=4214048

Family Applications (1)

Application Number Title Priority Date Filing Date
LTPA2007001C LTC0914118I2 (lt) 1996-06-25 2007-01-16 Pakeistieji 3,5-difenil-1,2,4-triazolai ir jų panaudojimas farmaciniais metalų chelatoriais

Country Status (36)

Country Link
US (3) US6465504B1 (lt)
EP (1) EP0914118B1 (lt)
JP (1) JP3541042B2 (lt)
KR (1) KR100616378B1 (lt)
CN (1) CN1146415C (lt)
AP (1) AP1127A (lt)
AR (1) AR007479A1 (lt)
AT (1) ATE226435T1 (lt)
AU (1) AU718037B2 (lt)
BG (1) BG64248B1 (lt)
BR (1) BR9709973A (lt)
CA (1) CA2255951C (lt)
CY (2) CY2429B1 (lt)
CZ (1) CZ291470B6 (lt)
DE (3) DE69716602T2 (lt)
DK (1) DK0914118T3 (lt)
ES (1) ES2187785T3 (lt)
FR (1) FR06C0049I2 (lt)
GE (1) GEP20084355B (lt)
HU (1) HU226232B1 (lt)
IL (1) IL127212A0 (lt)
LT (1) LTC0914118I2 (lt)
LU (1) LU91291I2 (lt)
MY (1) MY129541A (lt)
NL (1) NL300248I2 (lt)
NO (3) NO317180B1 (lt)
NZ (1) NZ333308A (lt)
OA (1) OA10946A (lt)
PL (1) PL194758B1 (lt)
PT (1) PT914118E (lt)
RU (1) RU2208010C2 (lt)
SI (1) SI0914118T1 (lt)
SK (1) SK284319B6 (lt)
TR (1) TR199802693T2 (lt)
TW (1) TW533205B (lt)
WO (1) WO1997049395A1 (lt)

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CN114276305B (zh) * 2021-12-28 2023-11-17 中山大学 一种三取代苯基-1,2,4-三氮唑衍生物及其制备和治疗神经元损伤的应用
CN114478410B (zh) * 2022-03-31 2022-11-29 中山大学 一种二取代苯基-1,2,4-三氮唑衍生物及其制备和应用
CN114591254B (zh) * 2022-03-31 2023-10-13 中山大学 一种3,5-二取代苯基-1,2,4-三氮唑衍生物及其制备方法和应用

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