LT2792677T - Naujas junginys, tinkamas degeneracinių ir uždegiminių ligų gydymui - Google Patents

Naujas junginys, tinkamas degeneracinių ir uždegiminių ligų gydymui

Info

Publication number: LT2792677T
Authority: LT; Lithuania
Prior art keywords: degenerative; treatment; inflammatory diseases; novel compound; compound useful
Prior art date: 2009-06-26

Application number

LTEP14175887.0T

Other languages

English (en)

Inventor

Javier Blanc

Christel Jeanne Marie Menet

Original Assignee

Galapagos Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-26

Filing date

2010-06-25

Publication date

2017-07-25

2010-06-25 Application filed by Galapagos Nv filed Critical Galapagos Nv

2017-07-25 Publication of LT2792677T publication Critical patent/LT2792677T/lt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)

LTEP14175887.0T 2009-06-26 2010-06-25 Naujas junginys, tinkamas degeneracinių ir uždegiminių ligų gydymui LT2792677T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22068509P	2009-06-26	2009-06-26
US29818810P	2010-01-25	2010-01-25

Publications (1)

Publication Number	Publication Date
LT2792677T true LT2792677T (lt)	2017-07-25

Family

ID=42340530

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP14175887.0T LT2792677T (lt)	2009-06-26	2010-06-25	Naujas junginys, tinkamas degeneracinių ir uždegiminių ligų gydymui

Country Status (37)

Country	Link
US (2)	US8796457B2 (lt)
EP (2)	EP2445912B1 (lt)
JP (1)	JP5486084B2 (lt)
KR (1)	KR101712561B1 (lt)
CN (1)	CN102459261B (lt)
AR (1)	AR077221A1 (lt)
AU (1)	AU2010264635B2 (lt)
BR (1)	BRPI1014759A2 (lt)
CA (1)	CA2765988C (lt)
CL (1)	CL2011003276A1 (lt)
CO (1)	CO6491039A2 (lt)
CR (1)	CR20110673A (lt)
CY (1)	CY1119711T1 (lt)
DK (2)	DK2792677T3 (lt)
DO (1)	DOP2011000378A (lt)
EA (1)	EA020111B1 (lt)
ES (2)	ES2519170T3 (lt)
HR (2)	HRP20141057T1 (lt)
HU (1)	HUE034205T2 (lt)
IL (1)	IL216618A (lt)
JO (1)	JO3030B1 (lt)
LT (1)	LT2792677T (lt)
MA (1)	MA33447B1 (lt)
ME (1)	ME01916B (lt)
MX (1)	MX2011013451A (lt)
NZ (1)	NZ596836A (lt)
PE (1)	PE20120494A1 (lt)
PL (2)	PL2792677T3 (lt)
PT (2)	PT2445912E (lt)
RS (1)	RS53617B1 (lt)
SG (1)	SG177359A1 (lt)
SI (2)	SI2792677T1 (lt)
SM (2)	SMT201700333T1 (lt)
TW (1)	TWI469981B (lt)
UY (1)	UY32741A (lt)
WO (1)	WO2010149771A1 (lt)
ZA (1)	ZA201109502B (lt)

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JO3030B1 (ar)	2009-06-26	2016-09-05	Galapagos Nv	مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات
TWI462920B (zh)	2009-06-26	2014-12-01	葛萊伯格有限公司	用於治療退化性及發炎疾病之新穎化合物
JO3417B1 (ar)	2010-01-08	2019-10-20	Regeneron Pharma	الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
US8637038B2 (en)	2011-04-12	2014-01-28	Rigel Pharmaceuticals, Inc.	Methods for inhibiting allograft rejection
SG10201914052TA (en) *	2011-10-11	2020-03-30	Sanofi Biotechnology	Compositions for the treatment of rheumatoid arthritis and methods of using same
TWI589299B (zh)	2011-10-11	2017-07-01	再生元醫藥公司	用於治療類風濕性關節炎之組成物及其使用方法
CN104379173A (zh) *	2012-06-22	2015-02-25	加拉帕戈斯股份有限公司	用于治疗炎症的氨基三唑并吡啶及其药物组合物
MA38884A1 (fr)	2013-09-05	2017-06-30	Hoffmann La Roche	Composé de triazolopyridine, compositions et procédés d'utilisation associés
PE20161246A1 (es)	2013-12-05	2016-11-25	Pfizer	Acrilamidas de pirrolo[2,3-d]pirimidinilo, pirrolo[2,3-b]pirazinilo y pirrolo[2,3-d]piridinilo
GB201402070D0 (en)	2014-02-07	2014-03-26	Galapagos Nv	Pharmaceutical compositions for the treatment of inflammatory disorders
GB201402071D0 (en)	2014-02-07	2014-03-26	Galapagos Nv	Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PL3283114T3 (pl) *	2015-04-13	2024-01-03	Galapagos Nv	Sposoby leczenia zaburzeń sercowo-naczyniowych
US11414413B2 (en)	2016-07-26	2022-08-16	Suzhou Longbiotech Pharmaceuticals Co., Ltd.	Heterocyclic compound as JAK inhibitor, and salts and therapeutic use thereof
US11427581B2 (en)	2018-01-31	2022-08-30	Zhuhai United Laboratories Co., Ltd.	JAK inhibitor and use thereof
KR20210049871A (ko)	2018-08-29	2021-05-06	리제너론 파아마슈티컬스, 인크.	류마티스성 관절염을 갖는 대상체를 치료하기 위한 방법 및 조성물
MX2021009242A (es)	2019-01-31	2021-10-26	Sanofi Biotechnology	Anticuerpo anti-receptor de il-6 para tratar la artritis juvenil idiopatica.
AU2020261431A1 (en)	2019-04-24	2021-12-09	Regeneron Pharmaceuticals, Inc.	Methods of diagnosis and treatment of rheumatoid arthritis
TW202110892A (zh)	2019-06-04	2021-03-16	法商賽諾菲生物技術公司	治療具有類風濕性關節炎的個體中疼痛之組成物及方法
CN111072655B (zh) *	2019-12-30	2021-12-10	深圳市坤健创新药物研究院	一种三氮唑并吡啶类化合物及其制备方法和药用组合物与应用
AU2021276656A1 (en)	2020-05-19	2022-11-24	Cybin Irl Limited	Deuterated tryptamine derivatives and methods of use
US11596612B1 (en)	2022-03-08	2023-03-07	PTC Innovations, LLC	Topical anesthetics

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JP2006517580A (ja)	2003-02-14	2006-07-27	ファイザー・プロダクツ・インク	抗炎症化合物としてのトリアゾロピリジン
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WO2010010189A1 (en)	2008-07-25	2010-01-28	Galapagos Nv	Novel compounds useful for the treatment of degenerative and inflammatory diseases
WO2010010188A1 (en)	2008-07-25	2010-01-28	Galapagos Nv	Novel compounds useful for the treatment of degenerative and inflammatory diseases.
WO2010010187A1 (en)	2008-07-25	2010-01-28	Galapagos Nv	Novel compounds useful for the treatment of degenerative and inflammatory diseases
JO3041B1 (ar)	2008-07-25	2016-09-05	Galapagos Nv	مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
BRPI1009637A2 (pt)	2009-06-05	2019-04-30	Cephalon, Inc	composto, composição e uso de um composto
TWI462920B (zh)	2009-06-26	2014-12-01	葛萊伯格有限公司	用於治療退化性及發炎疾病之新穎化合物
JO3030B1 (ar)	2009-06-26	2016-09-05	Galapagos Nv	مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات

2010
- 2010-05-31 JO JOP/2010/0179A patent/JO3030B1/ar active
- 2010-06-23 TW TW99120587A patent/TWI469981B/zh not_active IP Right Cessation
- 2010-06-24 AR ARP100102236A patent/AR077221A1/es active IP Right Grant
- 2010-06-25 EA EA201270076A patent/EA020111B1/ru not_active IP Right Cessation
- 2010-06-25 BR BRPI1014759A patent/BRPI1014759A2/pt active Search and Examination
- 2010-06-25 ES ES10728648.6T patent/ES2519170T3/es active Active
- 2010-06-25 EP EP10728648.6A patent/EP2445912B1/en active Active
- 2010-06-25 NZ NZ596836A patent/NZ596836A/xx not_active IP Right Cessation
- 2010-06-25 PL PL14175887T patent/PL2792677T3/pl unknown
- 2010-06-25 LT LTEP14175887.0T patent/LT2792677T/lt unknown
- 2010-06-25 JP JP2012516762A patent/JP5486084B2/ja active Active
- 2010-06-25 SG SG2011096179A patent/SG177359A1/en unknown
- 2010-06-25 PT PT107286486T patent/PT2445912E/pt unknown
- 2010-06-25 UY UY0001032741A patent/UY32741A/es not_active Application Discontinuation
- 2010-06-25 EP EP14175887.0A patent/EP2792677B1/en active Active
- 2010-06-25 CN CN201080028413.0A patent/CN102459261B/zh active Active
- 2010-06-25 SM SM20170333T patent/SMT201700333T1/it unknown
- 2010-06-25 DK DK14175887.0T patent/DK2792677T3/en active
- 2010-06-25 ES ES14175887.0T patent/ES2634325T3/es active Active
- 2010-06-25 PL PL10728648T patent/PL2445912T3/pl unknown
- 2010-06-25 KR KR1020127002060A patent/KR101712561B1/ko not_active Expired - Fee Related
- 2010-06-25 AU AU2010264635A patent/AU2010264635B2/en not_active Ceased
- 2010-06-25 RS RS20140614A patent/RS53617B1/sr unknown
- 2010-06-25 HR HRP20141057AT patent/HRP20141057T1/hr unknown
- 2010-06-25 HU HUE14175887A patent/HUE034205T2/en unknown
- 2010-06-25 MA MA34555A patent/MA33447B1/fr unknown
- 2010-06-25 ME MEP-2014-132A patent/ME01916B/me unknown
- 2010-06-25 PE PE2011002144A patent/PE20120494A1/es active IP Right Grant
- 2010-06-25 SI SI201031494T patent/SI2792677T1/sl unknown
- 2010-06-25 PT PT141758870T patent/PT2792677T/pt unknown
- 2010-06-25 SI SI201030775T patent/SI2445912T1/sl unknown
- 2010-06-25 US US12/823,682 patent/US8796457B2/en active Active
- 2010-06-25 MX MX2011013451A patent/MX2011013451A/es active IP Right Grant
- 2010-06-25 DK DK10728648.6T patent/DK2445912T3/da active
- 2010-06-25 CA CA2765988A patent/CA2765988C/en not_active Expired - Fee Related
- 2010-06-25 WO PCT/EP2010/059067 patent/WO2010149771A1/en not_active Ceased
2011
- 2011-11-27 IL IL216618A patent/IL216618A/en not_active IP Right Cessation
- 2011-12-06 DO DO2011000378A patent/DOP2011000378A/es unknown
- 2011-12-14 CR CR20110673A patent/CR20110673A/es unknown
- 2011-12-22 CL CL2011003276A patent/CL2011003276A1/es unknown
- 2011-12-22 ZA ZA2011/09502A patent/ZA201109502B/en unknown
2012
- 2012-01-16 CO CO12005375A patent/CO6491039A2/es active IP Right Grant
2014
- 2014-08-04 US US14/451,127 patent/US9505754B2/en active Active
- 2014-11-10 SM SM201400169T patent/SMT201400169B/xx unknown
2017
- 2017-07-04 HR HRP20171024TT patent/HRP20171024T1/hr unknown
- 2017-07-24 CY CY20171100784T patent/CY1119711T1/el unknown

Also Published As

Publication number	Publication date
TWI469981B (zh)	2015-01-21
EA020111B1 (ru)	2014-08-29
SI2792677T1 (sl)	2017-08-31
KR101712561B1 (ko)	2017-03-06
PE20120494A1 (es)	2012-05-17
RS53617B1 (sr)	2015-04-30
ES2519170T3 (es)	2014-11-06
HK1168098A1 (en)	2012-12-21
TW201103937A (en)	2011-02-01
ES2634325T3 (es)	2017-09-27
CR20110673A (es)	2012-02-09
IL216618A0 (en)	2012-02-29
HRP20171024T1 (hr)	2017-10-06
US20100331359A1 (en)	2010-12-30
SG177359A1 (en)	2012-02-28
PL2445912T3 (pl)	2015-02-27
ZA201109502B (en)	2012-09-26
US8796457B2 (en)	2014-08-05
DK2792677T3 (en)	2017-07-10
JP2012530767A (ja)	2012-12-06
MA33447B1 (fr)	2012-07-03
CO6491039A2 (es)	2012-07-31
UY32741A (es)	2011-01-31
KR20120059487A (ko)	2012-06-08
ME01916B (me)	2015-05-20
US9505754B2 (en)	2016-11-29
JO3030B1 (ar)	2016-09-05
SI2445912T1 (sl)	2014-12-31
DK2445912T3 (da)	2014-11-10
CL2011003276A1 (es)	2012-08-31
CA2765988A1 (en)	2010-12-29
CN102459261B (zh)	2014-11-05
EP2792677B1 (en)	2017-04-26
MX2011013451A (es)	2012-04-30
HRP20141057T1 (en)	2015-03-13
HUE034205T2 (en)	2018-01-29
EP2445912B1 (en)	2014-08-13
AU2010264635A1 (en)	2011-12-22
EP2792677A1 (en)	2014-10-22
CA2765988C (en)	2017-08-29
PT2445912E (pt)	2014-11-07
PL2792677T3 (pl)	2017-09-29
HK1202537A1 (en)	2015-10-02
BRPI1014759A2 (pt)	2016-04-19
PT2792677T (pt)	2017-07-06
SMT201400169B (it)	2015-01-15
IL216618A (en)	2014-09-30
CN102459261A (zh)	2012-05-16
SMT201700333T1 (it)	2017-09-07
EP2445912A1 (en)	2012-05-02
DOP2011000378A (es)	2012-02-15
JP5486084B2 (ja)	2014-05-07
AR077221A1 (es)	2011-08-10
US20150031671A1 (en)	2015-01-29
WO2010149771A1 (en)	2010-12-29
NZ596836A (en)	2013-02-22
AU2010264635B2 (en)	2015-05-07
EA201270076A1 (ru)	2012-08-30
CY1119711T1 (el)	2018-06-27

Publication	Publication Date	Title
ZA201109502B (en)	2012-09-26	Novel compound useful for the treatment of degenerative and inflammatory diseases
ZA201100396B (en)	2011-10-26	Novel compounds useful for the treatment of degenerative and inflammatory diseases
ZA201307793B (en)	2015-04-29	Novel compound useful for the treatment of degenerative and inflammatory diseases
ZA200707591B (en)	2009-08-26	Dihyrothienopyrimidines for the treatment of inflammatory diseases
BRPI1015569A2 (pt)	2016-08-16	compostos úteis para o tratamento de doenças degenerativas e inflamatórias.
ZA201202596B (en)	2014-03-26	Compounds for the treatment of dyslipidemia and related diseases
IL224544B (en)	2018-07-31	Compound useful for the treatment of nonsense-mutation-mediated diseases and pharmaceutical composition comprising said compound
IL215592A0 (en)	2011-12-29	Compositions and methods for the treatment of inflammation
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