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LT2455374T - Junginių, naudingų kaip sglt inhibitoriai, gamybos būdas - Google Patents

Junginių, naudingų kaip sglt inhibitoriai, gamybos būdas

Info

Publication number
LT2455374T
LT2455374T LTEP12156035.3T LT12156035T LT2455374T LT 2455374 T LT2455374 T LT 2455374T LT 12156035 T LT12156035 T LT 12156035T LT 2455374 T LT2455374 T LT 2455374T
Authority
LT
Lithuania
Prior art keywords
sglt
inhibitors
preparation
compounds useful
compounds
Prior art date
Application number
LTEP12156035.3T
Other languages
English (en)
Inventor
Walter Ferdinand Maria Filliers
Patrick Hubert J. Nieste
Masanori Hatsuda
Masahiko Yoshinaga
Mitsuhiro Yada
Christopher Teleha
Rudy Laurent Maria Broeckx
Original Assignee
Janssen Pharmaceutica N.V.
Mitsubishi Tanabe Pharma Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42106967&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2455374(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica N.V., Mitsubishi Tanabe Pharma Corporation filed Critical Janssen Pharmaceutica N.V.
Publication of LT2455374T publication Critical patent/LT2455374T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
LTEP12156035.3T 2008-10-17 2009-10-15 Junginių, naudingų kaip sglt inhibitoriai, gamybos būdas LT2455374T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10626008P 2008-10-17 2008-10-17
US10623108P 2008-10-17 2008-10-17
US12/578,934 US9056850B2 (en) 2008-10-17 2009-10-14 Process for the preparation of compounds useful as inhibitors of SGLT

Publications (1)

Publication Number Publication Date
LT2455374T true LT2455374T (lt) 2021-05-10

Family

ID=42106967

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP12156035.3T LT2455374T (lt) 2008-10-17 2009-10-15 Junginių, naudingų kaip sglt inhibitoriai, gamybos būdas
LTEP12156039.5T LT2457908T (lt) 2008-10-17 2009-10-15 Junginių, tinkamų naudoti kaip sglt inhibitorius, gavimo būdas

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP12156039.5T LT2457908T (lt) 2008-10-17 2009-10-15 Junginių, tinkamų naudoti kaip sglt inhibitorius, gavimo būdas

Country Status (30)

Country Link
US (1) US9056850B2 (lt)
EP (3) EP2455374B1 (lt)
JP (3) JP6123111B2 (lt)
KR (2) KR101724598B1 (lt)
CN (3) CN105541814A (lt)
AR (1) AR073892A1 (lt)
AU (1) AU2009305413B2 (lt)
BR (1) BRPI0920356B1 (lt)
CA (2) CA2740853C (lt)
CL (1) CL2011000849A1 (lt)
CY (3) CY1113867T1 (lt)
DK (3) DK2457908T3 (lt)
EA (1) EA021373B1 (lt)
ES (3) ES2854598T3 (lt)
HK (1) HK1224289A1 (lt)
HR (3) HRP20130254T1 (lt)
HU (2) HUE052432T2 (lt)
IL (2) IL212270A0 (lt)
LT (2) LT2455374T (lt)
MX (1) MX2011004054A (lt)
NZ (1) NZ592204A (lt)
PL (3) PL2457908T3 (lt)
PT (3) PT2455374T (lt)
RS (3) RS61484B1 (lt)
SI (3) SI2346888T1 (lt)
SM (4) SMT201700092T1 (lt)
TW (3) TWI588143B (lt)
UA (1) UA107450C2 (lt)
WO (1) WO2010043682A2 (lt)
ZA (1) ZA201103587B (lt)

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NZ703128A (en) * 2010-05-11 2016-04-29 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
AU2011276332A1 (en) * 2010-07-06 2013-01-17 Janssen Pharmaceutica Nv Formulation for co-therapy treatment of diabetes
EP2697218B1 (en) 2011-04-13 2016-05-25 Janssen Pharmaceutica NV Process for the preparation of compounds useful as inhibitors of sglt2
US9035044B2 (en) 2011-05-09 2015-05-19 Janssen Pharmaceutica Nv L-proline and citric acid co-crystals of (2S, 3R, 4R, 5S,6R)-2-(3-((5-(4-fluorophenyl)thiopen-2-yl)methyl)4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
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CN111057049B (zh) * 2019-11-18 2021-06-01 杭州华东医药集团新药研究院有限公司 一种卡格列净半水化合物的制备方法
CN113943329A (zh) * 2020-07-16 2022-01-18 尚科生物医药（上海）有限公司 一种坎格列净中间体的非对映异构体的制备方法
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CN113372326A (zh) * 2021-06-23 2021-09-10 江苏法安德医药科技有限公司 一种2-(4-氟苯基)噻吩的分离提纯方法
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JPWO2023080243A1 (lt) * 2021-11-08 2023-05-11
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