[go: up one dir, main page]

KR830009034A - 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법 - Google Patents

7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법 Download PDF

Info

Publication number
KR830009034A
KR830009034A KR1019820000163A KR820000163A KR830009034A KR 830009034 A KR830009034 A KR 830009034A KR 1019820000163 A KR1019820000163 A KR 1019820000163A KR 820000163 A KR820000163 A KR 820000163A KR 830009034 A KR830009034 A KR 830009034A
Authority
KR
South Korea
Prior art keywords
chloro
acid
tetrahydrokinolin
sulfuric acid
cyclized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019820000163A
Other languages
English (en)
Other versions
KR870001920B1 (ko
Inventor
부두앵 미셸
리나르 후버
Original Assignee
엠 삘라트
로오느-푸우랜크 상뜨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 엠 삘라트, 로오느-푸우랜크 상뜨 filed Critical 엠 삘라트
Publication of KR830009034A publication Critical patent/KR830009034A/ko
Application granted granted Critical
Publication of KR870001920B1 publication Critical patent/KR870001920B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)

Abstract

내용 없음

Description

7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 3-m-클로로아닐리노프로피온산을 발연황산으로 환화시킨 후, 하기 구조식(II)의 중간체 방향족 설폰산을 묽은 황산에 의해 탈설폰화시킨다음, 얻어진 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온을 분리시키는 것을 특징으로 하는 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법.
    상기식에서, n은 1 또는 2이다.
  2. 제1항에 있어서, 0-40℃에서 10-70%의 삼산화황을 함유하는 발연황산으로 환화시키는 것을 특징으로 하는 방법.
  3. 제1항에 있어서, 환화 초기에 삼산화황/3-m-클로로아닐리노프로피온산의 몰비가 5-10인 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 반응 혼합물을 물에 희석시킨후 120-180℃에서 가열함으로서 탈설폰화반응을 실시하는 것을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR8200163A 1981-01-16 1982-01-15 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법 Expired KR870001920B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR763 1981-01-16
FR8100763A FR2498185A1 (fr) 1981-01-16 1981-01-16 Procede de preparation de la chloro-7 tetrahydro-1,2,3,4 quinolinone-4

Publications (2)

Publication Number Publication Date
KR830009034A true KR830009034A (ko) 1983-12-17
KR870001920B1 KR870001920B1 (ko) 1987-10-22

Family

ID=9254221

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8200163A Expired KR870001920B1 (ko) 1981-01-16 1982-01-15 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법

Country Status (13)

Country Link
US (1) US4421918A (ko)
EP (1) EP0056764B1 (ko)
JP (1) JPS57171971A (ko)
KR (1) KR870001920B1 (ko)
AT (1) ATE5721T1 (ko)
CA (1) CA1167041A (ko)
DE (1) DE3260022D1 (ko)
DK (1) DK148803C (ko)
FR (1) FR2498185A1 (ko)
HU (1) HU184983B (ko)
IE (1) IE51959B1 (ko)
IN (1) IN157561B (ko)
ZA (1) ZA82279B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114105871B (zh) * 2021-12-06 2023-11-14 青岛科技大学 一种8-羟基喹啉的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR806715A (fr) * 1936-01-11 1936-12-23 Ig Farbenindustrie Ag Procédé pour préparer des composés hétérocycliques de l'azote
US3281836A (en) * 1948-08-26 1966-10-25 Brown Robert Hanbury Interrogation gain control
US2558211A (en) * 1949-04-14 1951-06-26 Lilly Co Eli Preparation of 4-hydroxyquinoline compounds
FR1202105A (fr) 1956-06-14 1960-01-07 Basf Ag Procédé pour la production de quinolones-4 comportant un groupe hydoxyle sur le noyau benzénique
BE638349A (ko) * 1963-08-30
FR1514280A (fr) * 1967-01-10 1968-02-23 Roussel Uclaf Nouveau procédé de préparation de quinoléines substituées et produits ainsi obtenus

Also Published As

Publication number Publication date
HU184983B (en) 1984-11-28
EP0056764A1 (fr) 1982-07-28
JPS57171971A (en) 1982-10-22
DE3260022D1 (en) 1984-02-02
IE820077L (en) 1982-07-16
DK148803B (da) 1985-10-07
IE51959B1 (en) 1987-04-29
JPH0155270B2 (ko) 1989-11-22
DK16382A (da) 1982-07-17
KR870001920B1 (ko) 1987-10-22
US4421918A (en) 1983-12-20
CA1167041A (fr) 1984-05-08
ZA82279B (en) 1982-11-24
ATE5721T1 (de) 1984-01-15
FR2498185B1 (ko) 1983-08-26
IN157561B (ko) 1986-04-26
FR2498185A1 (fr) 1982-07-23
EP0056764B1 (fr) 1983-12-28
DK148803C (da) 1986-04-01

Similar Documents

Publication Publication Date Title
KR830007488A (ko) 안트라퀴논과 그 치환유도체류의 제조방법
KR830009034A (ko) 7-클로로-1,2,3,4-테트라하이드로키놀린-4-온의 제조방법
ATE55102T1 (de) Verfahren zur herstellung von trifluoromethyliodid.
GB1494979A (en) Process for the production of 1-aminobenzene-4-and-5-beta-sulphatoethylsulphone-2-sulphonic acid and their hydroxyethylsulphone-and vinylsulphone derivatives
KR880009937A (ko) 치환된 3-알킬퀴놀린-8-카르복실산의 제조방법
KR860008174A (ko) 항정신질환성 벤지소티아졸 s-산화물의 제조방법
GB1084375A (en) Method of making tetrabromophthalic acid anhydride
KR900701746A (ko) 2-할로-4-알킬술포닐벤조산의 제조방법
KR850000416A (ko) 디안트라퀴논-n,n'-디히드라진 및 그의 염소화 생성물의 제조방법
KR830009077A (ko) 푸란 유도체의 제조방법
GB927971A (en) Process for separating hydrocarbons
GB1370413A (en) Process for the production of anthraquinone sulphonic acids
ATE257T1 (de) Verfahren zur herstellung von naphthalin-1,3,5-trisulfonsaeure.
EP0300275A3 (de) Verfahren zur Herstellung von Aminoaryl-sulfonsäuren
KR830004234A (ko) 폴리설파이드 연쇄반응정지제 제조공정
KR840009285A (ko) 분지상 알카노인산의 제조방법
GB193029A (en) Process for purifying mineral oils
SU108138A1 (ru) Способ получени сульфокислот
KR960010671A (ko) 5h- 페닐-3,13- 디설포네이토디벤조포스폴 및 이의 제조방법
BG34339A3 (bg) Метод за отделяне на киселини от течни въглеводородни фракции
KR960022358A (ko) 시멘트용 가소제의 제조방법
KR890003677A (ko) 술폰화 3,3'-디클로로벤지딘 화합물 및 그의 제법
KR910004553A (ko) 7-하이드록시-1,2-나프트퀴논-2-디아지드-4-설폰산 또는 이의 염의 제조방법 및 이의 용도
GB907613A (en) Improvements relating to the purification of 2-naphthalene sulphonic acid
KR900004676A (ko) 1-아미노-2-클로로-4-히드록시안트라 퀴논의 제법

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19911023

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19911023