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KR830006229A - 이미다졸 유도체의 제조방법 - Google Patents

이미다졸 유도체의 제조방법 Download PDF

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Publication number
KR830006229A
KR830006229A KR1019810002007A KR810002007A KR830006229A KR 830006229 A KR830006229 A KR 830006229A KR 1019810002007 A KR1019810002007 A KR 1019810002007A KR 810002007 A KR810002007 A KR 810002007A KR 830006229 A KR830006229 A KR 830006229A
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KR
South Korea
Prior art keywords
hydrogen
imidazole derivative
alkyl
methyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019810002007A
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English (en)
Other versions
KR850000126B1 (ko
Inventor
데룽스 로마노
Original Assignee
쿠르트 네젤보쉬
에프. 호프만-라 롯슈 앤드 캄파니 아크티에게젤샤프트
한스 스튀클린
에프. 호프만-라 롯슈 앤드 캄파니 아크 티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 쿠르트 네젤보쉬, 에프. 호프만-라 롯슈 앤드 캄파니 아크티에게젤샤프트, 한스 스튀클린, 에프. 호프만-라 롯슈 앤드 캄파니 아크 티엔게젤샤프트 filed Critical 쿠르트 네젤보쉬
Publication of KR830006229A publication Critical patent/KR830006229A/ko
Application granted granted Critical
Publication of KR850000126B1 publication Critical patent/KR850000126B1/ko
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)

Abstract

내용 없음

Description

이미다졸 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 다음 구조식(Ⅱ)의 티에피노 이미다졸 또는 이들의 산부가염을 탈황촉매로 처리하여 다음 구조식(I)의 이미다졸 유도체 또는 이들의 생리학적으로 무독한 염을 제조하는 방법.
    상기 구조식에서
    X는 수소 또는 C1~4-n-알킬이며
    Y는 임의로 메틸 또는 불소에 의해 치환된 티에닐 또는 구조식(Y')의 그룹이고
    여기서
    R1,R2및 R3는 수소, 메틸, 불소, 하이드록시, 메톡시이거나 R1,R2및 R3중 2개가 인접한 탄소원자와 함께 메틸렌 디옥시 또는 에틸렌디옥시를 형성하거나, R1,R2및 R3중 하나는 모노-또는 디-(C1~4-n-알킬)-아미노이고 다른 두개는 수소이다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810002007A 1980-06-05 1981-06-04 이미다졸 유도체의 제조방법 Expired KR850000126B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH434780 1980-06-05
CH4347/80 1980-06-05

Publications (2)

Publication Number Publication Date
KR830006229A true KR830006229A (ko) 1983-09-20
KR850000126B1 KR850000126B1 (ko) 1985-02-27

Family

ID=4274400

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002007A Expired KR850000126B1 (ko) 1980-06-05 1981-06-04 이미다졸 유도체의 제조방법

Country Status (22)

Country Link
US (1) US4582844A (ko)
EP (1) EP0041652B1 (ko)
JP (1) JPS5731667A (ko)
KR (1) KR850000126B1 (ko)
AT (1) ATE6369T1 (ko)
AU (1) AU7111581A (ko)
BR (1) BR8103553A (ko)
CA (1) CA1161847A (ko)
CS (1) CS220340B2 (ko)
DE (1) DE3162356D1 (ko)
DK (1) DK193181A (ko)
ES (1) ES502777A0 (ko)
FI (1) FI811527L (ko)
GR (1) GR77076B (ko)
IL (1) IL63009A0 (ko)
MC (1) MC1394A1 (ko)
NO (1) NO811908L (ko)
NZ (1) NZ197248A (ko)
PH (1) PH15876A (ko)
PT (1) PT73143B (ko)
ZA (1) ZA813644B (ko)
ZW (1) ZW10781A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501892A (en) * 1982-07-28 1985-02-26 The Upjohn Company Pyridyl benzenediols
IT1193608B (it) * 1983-01-21 1988-07-21 Pierrel Spa Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico
US4790775A (en) * 1988-02-09 1988-12-13 E. I. Du Pont De Nemours And Company Transition connector
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
JP6064653B2 (ja) * 2013-02-15 2017-01-25 東洋インキＳｃホールディングス株式会社 蛍光材料、蛍光性樹脂組成物および化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE585507A (ko) * 1960-03-31
US3473901A (en) * 1963-02-08 1969-10-21 Rohm & Haas Fuel compositions
CH496710A (de) * 1967-12-16 1970-09-30 Basf Ag Verfahren zur Herstellung von substituierten Imidazolen
DD99787A1 (ko) * 1969-06-23 1973-08-20
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles
DE2701372A1 (de) * 1977-01-14 1978-07-20 Veba Chemie Ag Verfahren zur herstellung cyclischer amidine
DE2733466A1 (de) * 1977-07-25 1979-02-22 Basf Ag Verfahren zur herstellung von imidazolen

Also Published As

Publication number Publication date
CS220340B2 (en) 1983-03-25
GR77076B (ko) 1984-09-06
DE3162356D1 (en) 1984-03-29
NO811908L (no) 1981-12-07
PT73143B (en) 1983-05-11
EP0041652A1 (de) 1981-12-16
EP0041652B1 (de) 1984-02-22
US4582844A (en) 1986-04-15
ZW10781A1 (en) 1981-12-30
PH15876A (en) 1983-04-13
ATE6369T1 (de) 1984-03-15
AU7111581A (en) 1981-12-10
DK193181A (da) 1981-12-06
NZ197248A (en) 1984-07-31
KR850000126B1 (ko) 1985-02-27
CA1161847A (en) 1984-02-07
BR8103553A (pt) 1982-03-02
ES8300755A1 (es) 1982-11-16
MC1394A1 (fr) 1982-04-27
IL63009A0 (en) 1981-09-13
FI811527A7 (fi) 1981-12-06
FI811527L (fi) 1981-12-06
JPS5731667A (en) 1982-02-20
ZA813644B (en) 1982-06-30
ES502777A0 (es) 1982-11-16
PT73143A (en) 1981-07-01

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