JP2012527461A - 真菌を防除するための化合物および方法 - Google Patents

真菌を防除するための化合物および方法 Download PDF

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Publication number: JP2012527461A
Authority: JP; Japan
Prior art keywords: substituted; unsubstituted; alkyl; compounds; compound
Prior art date: 2009-05-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2012511870A

Other languages

English (en)

Japanese (ja)

Inventor

デイヴィス，ジョージ

ロー，ウィリアム

レンガ，ジェームス

ティスデル，フランシス

ヤップ，モーリス

ヤング，デイヴィッド

Original Assignee

ダウアグロサイエンシィズエルエルシー

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-05-19

Filing date

2010-05-03

Publication date

2012-11-08

2010-05-03 Application filed by ダウアグロサイエンシィズエルエルシー filed Critical ダウアグロサイエンシィズエルエルシー

2012-11-08 Publication of JP2012527461A publication Critical patent/JP2012527461A/ja

Status Pending legal-status Critical Current

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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UY34632A (es)	2012-02-24	2013-05-31	Novartis Ag	Compuestos de oxazolidin- 2- ona y usos de los mismos
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Citations (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345640A (en) *	1971-02-01	1974-01-30	Shell Int Research	Piperazinyl pyrimidines
JPS57179167A (en) *	1981-04-07	1982-11-04	Pharmindustrie	Piperazinopyrimidine compound and manufacture
JPS60214777A (ja) *	1984-02-17	1985-10-28	ワ−ナ−−ランバ−ト・コンパニ−	抗菌剤
US5250530A (en) *	1989-07-11	1993-10-05	Hoechst Aktiengesellschaft	Aminopyrimidine derivatives, and their use as fungicides
US5792778A (en) *	1995-08-10	1998-08-11	Merck & Co., Inc.	2-substituted aryl pyrroles, compositions containing such compounds and methods of use
US5859041A (en) *	1996-06-10	1999-01-12	Merck & Co., Inc.	Substituted imidazoles having cytokine inhibitory activity
WO1999021840A1 (en) *	1997-10-28	1999-05-06	Warner-Lambert Company	Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents
US5958934A (en) *	1996-05-23	1999-09-28	Syntex (U.S.A.) Inc.	Aryl pyrimidine derivatives and uses thereof
JP2002503245A (ja) *	1997-06-12	2002-01-29	ローン−プーラン・ロレ・リミテツド	イミダゾリル−環式アセタール
JP2002543188A (ja) *	1999-05-04	2002-12-17	シンジェンタパーティシペーションズアクチェンゲゼルシャフト	農薬ピリミジン誘導体
WO2003000682A1 (en) *	2001-06-25	2003-01-03	Merck & Co., Inc.	(pyrimidyl)(phenyl)substituted fused heteroaryl p38 inhibiting and pkg kinase inhibiting compounds
JP2003503311A (ja) *	1999-04-14	2003-01-28	ノバルティスアクチエンゲゼルシャフト	置換アゾール類
US6525059B1 (en) *	1998-11-20	2003-02-25	G. D. Searle & Company	Substituted pyrazoles as p38 kinase inhibitors
JP2003512467A (ja) *	1999-10-27	2003-04-02	ノバルティスアクチエンゲゼルシャフト	チアゾールおよびイミダゾ（４，５−ｂ）ピリジン化合物ならびにそれらの医薬用途
WO2003026661A1 (fr) *	2001-09-14	2003-04-03	Yamanouchi Pharmaceutical Co., Ltd.	Accelerateur de secretion de l'insuline et nouveau derive de pyrimidine
JP2003535062A (ja) *	2000-06-01	2003-11-25	メルクエンドカムパニーインコーポレーテッド	Ｊｎｋ阻害剤としての（二置換フェニル）ピリミジニルイミダゾール誘導体の使用
JP2004506736A (ja) *	2000-08-22	2004-03-04	グラクソ　グループ　リミテッド	タンパク質キナーゼ阻害剤としての縮合ピラゾール誘導体
JP2004525149A (ja) *	2001-03-30	2004-08-19	スミスクラインビーチャムコーポレーション	ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
JP2004525150A (ja) *	2001-03-30	2004-08-19	スミスクラインビーチャムコーポレーション	治療用化合物としてのピラゾロピリジン類の使用
JP2004529119A (ja) *	2001-03-08	2004-09-24	スミスクラインビーチャムコーポレーション	ピラゾロピリジン誘導体
JP2004339210A (ja) *	2003-04-21	2004-12-02	Tanabe Seiyaku Co Ltd	ｐ３８ＭＡＰキナーゼ阻害剤
JP2005504081A (ja) *	2001-09-20	2005-02-10	ザプロクターアンドギャンブルカンパニー	炎症性サイトカインの放出を阻害する化合物
WO2005100353A1 (en) *	2004-04-15	2005-10-27	Almirall Prodesfarma, Sa	Condensed pyridine derivatives useful as a28 adenosine receptor antagonists
US6979686B1 (en) *	2001-12-07	2005-12-27	Pharmacia Corporation	Substituted pyrazoles as p38 kinase inhibitors
JP2006502164A (ja) *	2002-09-06	2006-01-19	バイオジェン・アイデック・エムエイ・インコーポレイテッド	イミダゾロピリジンならびにその生成および使用方法
JP2006502189A (ja) *	2002-09-18	2006-01-19	ザプロクターアンドギャンブルカンパニー	炎症性サイトカインを抑制する６，７−ジヒドロ−５Ｈ−ピラゾロ［１，２−ａ］ピラゾール−１−オン
JP2006504755A (ja) *	2002-10-15	2006-02-09	スミスクラインビーチャムコーポレーション	Ｇｓｋ−３阻害薬としてのピリダジン化合物
JP2006506462A (ja) *	2002-08-14	2006-02-23	バーテックス　ファーマシューティカルズ　インコーポレイテッド	プロテインキナーゼインヒビターおよびそれらの使用
JP2006515916A (ja) *	2002-08-21	2006-06-08	ザクト‐デザイン、アンド、エンジニアリング、プロプライエタリー、リミテッド	トルク伝達機構
JP2006528983A (ja) *	2003-05-15	2006-12-28	アークルインコーポレイテッド	ｐ３８の阻害物質としてのイミダゾチアゾール類およびイミダゾオキサゾール誘導体
WO2006137658A1 (en) *	2005-06-20	2006-12-28	Dongbu Hitek Co., Ltd.	New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory acitivity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
JP2007514003A (ja) *	2003-12-15	2007-05-31	アルミラルプロデスファルマアーゲー	アデノシン受容体アンタゴニストとしての２，６−ビスヘテロアリール−４−アミノピリミジン
WO2007083692A1 (ja) *	2006-01-23	2007-07-26	Kumiai Chemical Industry Co., Ltd.	アミノピリミジン誘導体及び農園芸用植物病害防除剤
WO2007084560A2 (en) *	2006-01-17	2007-07-26	Signal Pharmaceuticals, Llc	INHIBITORS OF TNFα, PDE4 AND B-RAF, COMPOSITIONS THEREOF AND METHODS OF USE THEREWITH
JP2007534671A (ja) *	2004-03-02	2007-11-29	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	４−ベンゾイミダゾール−２−イル−ピリダジン−３−オン−誘導体、その製造および医薬におけるその使用
JP2007534624A (ja) *	2003-07-16	2007-11-29	ニューロジェン・コーポレーション	ビアリールピペラジニル−ピリジン類縁体
WO2007146087A2 (en) *	2006-06-06	2007-12-21	Avigen, Inc.	SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE
JP2008503522A (ja) *	2004-06-25	2008-02-07	ビーエーエスエフ　アクチェンゲゼルシャフト	２−置換ピリジン類、それらの製造方法および有害菌を抑制するためのそれらの使用
JP2008505166A (ja) *	2004-07-01	2008-02-21	アストラゼネカアクチボラグ	抗癌剤としてのアジン−カルボキサミド
JP2008516962A (ja) *	2004-10-15	2008-05-22	バイオジェン・アイデック・エムエイ・インコーポレイテッド	血管傷害を治療する方法
WO2008079346A1 (en) *	2006-12-21	2008-07-03	Vertex Pharmaceuticals Incorporated	5-cyan0-4- (pyrrolo [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors
WO2008080938A1 (en) *	2006-12-28	2008-07-10	Basf Se	Use 2-substituted pyridines for cancer treatment
JP2008528473A (ja) *	2005-01-25	2008-07-31	アストラゼネカアクチボラグ	化学物質
JP2009507032A (ja) *	2005-09-02	2009-02-19	アボット・ラボラトリーズ	新規なイミダゾ系複素環
WO2009071701A1 (en) *	2007-12-07	2009-06-11	Novartis Ag	Pyrazole derivatives and use thereof as inhibitors of cyclin dependent kinases
WO2009076440A2 (en) *	2007-12-12	2009-06-18	E.I. Du Pont De Nemours And Company	Fungicidal bicyclic pyrazoles
WO2009081112A2 (en) *	2007-12-24	2009-07-02	Syngenta Limited	Chemical compounds
WO2009087212A2 (en) *	2008-01-11	2009-07-16	Novartis Ag	Pyridine derivatives
WO2009109907A1 (en) *	2008-03-06	2009-09-11	Actelion Pharmaceuticals Ltd	Novel pyrimidine-pyridine derivatives
WO2009125870A1 (en) *	2008-04-09	2009-10-15	Mitsubishi Tanabe Pharma Corporation	Pyrimidine, pyridine and triazine derivatives as maxi-k channel openers.
JP2009542940A (ja) *	2006-06-27	2009-12-03	ユナイテッド・ステイツ・ジプサム・カンパニー	基礎を構築する不燃性の強化セメント質軽量パネル及び金属枠システム
WO2009152325A1 (en) *	2008-06-12	2009-12-17	Janssen Pharmaceutica Nv	Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor
JP2010536492A (ja) *	2007-08-23	2010-12-02	エヌティーケイエンタープライズ、インコーポレイテッド	間質コラーゲンの収縮をほとんど又はまったく生じないようにｌｔｋ及び他の外科的な眼科手術を規定し制御するシステム並びに方法
JP2010538128A (ja) *	2007-08-31	2010-12-09	マーテックバイオサイエンシーズコーポレーション	多価不飽和脂肪酸を含む固体脂肪組成物ならびにその使用および製造の方法
JP2010538892A (ja) *	2007-09-18	2010-12-16	エアバス・オペレイションズ・ゲーエムベーハー	航空機又は宇宙船の細分化用圧力隔壁及び細分化方法
JP2010540962A (ja) *	2007-10-04	2010-12-24	ローレンス・リバモア・ナショナル・セキュリティ・エルエルシー	レーザー慣性閉じ込め核融合・核分裂発電プラントの制御
JP2011513686A (ja) *	2008-02-29	2011-04-28	オー−フレックス・テクノロジーズ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	太陽熱システム

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6052146B2 (ja)	1979-12-25	1985-11-18	石原産業株式会社	Ｎ−ピリジルアニリン系化合物、それらの製造方法及びそれらを含有する有害生物防除剤
US4791110A (en) *	1985-06-14	1988-12-13	Eli Lilly And Company	Fungicidal pyridazines
TW440563B (en) *	1996-05-23	2001-06-16	Hoffmann La Roche	Aryl pyrimidine derivatives and a pharmaceutical composition thereof
GB9927844D0 (en) *	1999-11-26	2000-01-26	Glaxo Group Ltd	Chemical compounds
ES2234433B1 (es) *	2003-12-15	2006-11-01	Almirall Prodesfarma, S.A.	4-aminopirimidinas como antagonistas de receptores de adenosina.
DE102007010801A1 (de) *	2007-03-02	2008-09-04	Bayer Cropscience Ag	Diaminopyrimidine als Fungizide
DE102007061756A1 (de) *	2007-12-20	2009-06-25	Bayer Healthcare Ag	Substituierte 4-Aminopyrimidin-5-carbonsäuren und ihre Verwendung

2010
- 2010-05-03 CA CA2760911A patent/CA2760911A1/en not_active Abandoned
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- 2010-05-03 KR KR1020117027465A patent/KR20120016247A/ko not_active Withdrawn
- 2010-05-03 RU RU2011151603/04A patent/RU2011151603A/ru not_active Application Discontinuation
- 2010-05-03 WO PCT/US2010/033327 patent/WO2010135070A1/en not_active Ceased
- 2010-05-03 US US12/772,248 patent/US8759356B2/en not_active Expired - Fee Related
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- 2010-05-03 CN CN2010800221108A patent/CN102438993A/zh active Pending
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- 2010-05-03 SI SI201030324T patent/SI2432767T1/sl unknown
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2014
- 2014-05-28 US US14/288,797 patent/US20140275123A1/en not_active Abandoned

Patent Citations (58)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345640A (en) *	1971-02-01	1974-01-30	Shell Int Research	Piperazinyl pyrimidines
JPS57179167A (en) *	1981-04-07	1982-11-04	Pharmindustrie	Piperazinopyrimidine compound and manufacture
JPS60214777A (ja) *	1984-02-17	1985-10-28	ワ−ナ−−ランバ−ト・コンパニ−	抗菌剤
US5250530A (en) *	1989-07-11	1993-10-05	Hoechst Aktiengesellschaft	Aminopyrimidine derivatives, and their use as fungicides
US5792778A (en) *	1995-08-10	1998-08-11	Merck & Co., Inc.	2-substituted aryl pyrroles, compositions containing such compounds and methods of use
US5958934A (en) *	1996-05-23	1999-09-28	Syntex (U.S.A.) Inc.	Aryl pyrimidine derivatives and uses thereof
US5859041A (en) *	1996-06-10	1999-01-12	Merck & Co., Inc.	Substituted imidazoles having cytokine inhibitory activity
JP2002503245A (ja) *	1997-06-12	2002-01-29	ローン−プーラン・ロレ・リミテツド	イミダゾリル−環式アセタール
WO1999021840A1 (en) *	1997-10-28	1999-05-06	Warner-Lambert Company	Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents
US6525059B1 (en) *	1998-11-20	2003-02-25	G. D. Searle & Company	Substituted pyrazoles as p38 kinase inhibitors
JP2003503311A (ja) *	1999-04-14	2003-01-28	ノバルティスアクチエンゲゼルシャフト	置換アゾール類
JP2002543188A (ja) *	1999-05-04	2002-12-17	シンジェンタパーティシペーションズアクチェンゲゼルシャフト	農薬ピリミジン誘導体
JP2003512467A (ja) *	1999-10-27	2003-04-02	ノバルティスアクチエンゲゼルシャフト	チアゾールおよびイミダゾ（４，５−ｂ）ピリジン化合物ならびにそれらの医薬用途
JP2003535062A (ja) *	2000-06-01	2003-11-25	メルクエンドカムパニーインコーポレーテッド	Ｊｎｋ阻害剤としての（二置換フェニル）ピリミジニルイミダゾール誘導体の使用
JP2004506736A (ja) *	2000-08-22	2004-03-04	グラクソ　グループ　リミテッド	タンパク質キナーゼ阻害剤としての縮合ピラゾール誘導体
JP2004529119A (ja) *	2001-03-08	2004-09-24	スミスクラインビーチャムコーポレーション	ピラゾロピリジン誘導体
JP2004525149A (ja) *	2001-03-30	2004-08-19	スミスクラインビーチャムコーポレーション	ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
JP2004525150A (ja) *	2001-03-30	2004-08-19	スミスクラインビーチャムコーポレーション	治療用化合物としてのピラゾロピリジン類の使用
WO2003000682A1 (en) *	2001-06-25	2003-01-03	Merck & Co., Inc.	(pyrimidyl)(phenyl)substituted fused heteroaryl p38 inhibiting and pkg kinase inhibiting compounds
WO2003026661A1 (fr) *	2001-09-14	2003-04-03	Yamanouchi Pharmaceutical Co., Ltd.	Accelerateur de secretion de l'insuline et nouveau derive de pyrimidine
JP2005504081A (ja) *	2001-09-20	2005-02-10	ザプロクターアンドギャンブルカンパニー	炎症性サイトカインの放出を阻害する化合物
US6979686B1 (en) *	2001-12-07	2005-12-27	Pharmacia Corporation	Substituted pyrazoles as p38 kinase inhibitors
JP2006506462A (ja) *	2002-08-14	2006-02-23	バーテックス　ファーマシューティカルズ　インコーポレイテッド	プロテインキナーゼインヒビターおよびそれらの使用
JP2006515916A (ja) *	2002-08-21	2006-06-08	ザクト‐デザイン、アンド、エンジニアリング、プロプライエタリー、リミテッド	トルク伝達機構
JP2006502164A (ja) *	2002-09-06	2006-01-19	バイオジェン・アイデック・エムエイ・インコーポレイテッド	イミダゾロピリジンならびにその生成および使用方法
JP2006502189A (ja) *	2002-09-18	2006-01-19	ザプロクターアンドギャンブルカンパニー	炎症性サイトカインを抑制する６，７−ジヒドロ−５Ｈ−ピラゾロ［１，２−ａ］ピラゾール−１−オン
JP2006504755A (ja) *	2002-10-15	2006-02-09	スミスクラインビーチャムコーポレーション	Ｇｓｋ−３阻害薬としてのピリダジン化合物
JP2004339210A (ja) *	2003-04-21	2004-12-02	Tanabe Seiyaku Co Ltd	ｐ３８ＭＡＰキナーゼ阻害剤
JP2006528983A (ja) *	2003-05-15	2006-12-28	アークルインコーポレイテッド	ｐ３８の阻害物質としてのイミダゾチアゾール類およびイミダゾオキサゾール誘導体
JP2007534624A (ja) *	2003-07-16	2007-11-29	ニューロジェン・コーポレーション	ビアリールピペラジニル−ピリジン類縁体
JP2007514003A (ja) *	2003-12-15	2007-05-31	アルミラルプロデスファルマアーゲー	アデノシン受容体アンタゴニストとしての２，６−ビスヘテロアリール−４−アミノピリミジン
JP2007534671A (ja) *	2004-03-02	2007-11-29	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	４−ベンゾイミダゾール−２−イル−ピリダジン−３−オン−誘導体、その製造および医薬におけるその使用
JP2007532603A (ja) *	2004-04-15	2007-11-15	ラボラトリオス・アルミラル・ソシエダッド・アノニマ	Ａ２ｂアデノシン受容体アンタゴニストとして有用なピリジン誘導体
WO2005100353A1 (en) *	2004-04-15	2005-10-27	Almirall Prodesfarma, Sa	Condensed pyridine derivatives useful as a28 adenosine receptor antagonists
JP2008503522A (ja) *	2004-06-25	2008-02-07	ビーエーエスエフ　アクチェンゲゼルシャフト	２−置換ピリジン類、それらの製造方法および有害菌を抑制するためのそれらの使用
JP2008505166A (ja) *	2004-07-01	2008-02-21	アストラゼネカアクチボラグ	抗癌剤としてのアジン−カルボキサミド
JP2008516962A (ja) *	2004-10-15	2008-05-22	バイオジェン・アイデック・エムエイ・インコーポレイテッド	血管傷害を治療する方法
JP2008528473A (ja) *	2005-01-25	2008-07-31	アストラゼネカアクチボラグ	化学物質
WO2006137658A1 (en) *	2005-06-20	2006-12-28	Dongbu Hitek Co., Ltd.	New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory acitivity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
JP2009507032A (ja) *	2005-09-02	2009-02-19	アボット・ラボラトリーズ	新規なイミダゾ系複素環
WO2007084560A2 (en) *	2006-01-17	2007-07-26	Signal Pharmaceuticals, Llc	INHIBITORS OF TNFα, PDE4 AND B-RAF, COMPOSITIONS THEREOF AND METHODS OF USE THEREWITH
WO2007083692A1 (ja) *	2006-01-23	2007-07-26	Kumiai Chemical Industry Co., Ltd.	アミノピリミジン誘導体及び農園芸用植物病害防除剤
WO2007146087A2 (en) *	2006-06-06	2007-12-21	Avigen, Inc.	SUBSTITUTED PYRAZOLO [1,5-α] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE
JP2009542940A (ja) *	2006-06-27	2009-12-03	ユナイテッド・ステイツ・ジプサム・カンパニー	基礎を構築する不燃性の強化セメント質軽量パネル及び金属枠システム
WO2008079346A1 (en) *	2006-12-21	2008-07-03	Vertex Pharmaceuticals Incorporated	5-cyan0-4- (pyrrolo [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors
WO2008080938A1 (en) *	2006-12-28	2008-07-10	Basf Se	Use 2-substituted pyridines for cancer treatment
JP2010536492A (ja) *	2007-08-23	2010-12-02	エヌティーケイエンタープライズ、インコーポレイテッド	間質コラーゲンの収縮をほとんど又はまったく生じないようにｌｔｋ及び他の外科的な眼科手術を規定し制御するシステム並びに方法
JP2010538128A (ja) *	2007-08-31	2010-12-09	マーテックバイオサイエンシーズコーポレーション	多価不飽和脂肪酸を含む固体脂肪組成物ならびにその使用および製造の方法
JP2010538892A (ja) *	2007-09-18	2010-12-16	エアバス・オペレイションズ・ゲーエムベーハー	航空機又は宇宙船の細分化用圧力隔壁及び細分化方法
JP2010540962A (ja) *	2007-10-04	2010-12-24	ローレンス・リバモア・ナショナル・セキュリティ・エルエルシー	レーザー慣性閉じ込め核融合・核分裂発電プラントの制御
WO2009071701A1 (en) *	2007-12-07	2009-06-11	Novartis Ag	Pyrazole derivatives and use thereof as inhibitors of cyclin dependent kinases
WO2009076440A2 (en) *	2007-12-12	2009-06-18	E.I. Du Pont De Nemours And Company	Fungicidal bicyclic pyrazoles
WO2009081112A2 (en) *	2007-12-24	2009-07-02	Syngenta Limited	Chemical compounds
WO2009087212A2 (en) *	2008-01-11	2009-07-16	Novartis Ag	Pyridine derivatives
JP2011513686A (ja) *	2008-02-29	2011-04-28	オー−フレックス・テクノロジーズ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	太陽熱システム
WO2009109907A1 (en) *	2008-03-06	2009-09-11	Actelion Pharmaceuticals Ltd	Novel pyrimidine-pyridine derivatives
WO2009125870A1 (en) *	2008-04-09	2009-10-15	Mitsubishi Tanabe Pharma Corporation	Pyrimidine, pyridine and triazine derivatives as maxi-k channel openers.
WO2009152325A1 (en) *	2008-06-12	2009-12-17	Janssen Pharmaceutica Nv	Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BIOORG. MED. CHEM. LETT., vol. １４, JPN6014026111, 2004, pages 2083 - 2086, ISSN: 0002839004 *
BIOORG. MED. CHEM. LETT., vol. １９, JPN6014026093, 13 March 2009 (2009-03-13), pages 2099 - 2102, ISSN: 0002839001 *
COMPTES RENDUS DE L'ACADEMIE BULGARE DES SCIENCE, vol. ３４, JPN6014026120, 1981, pages 1677 - 1680, ISSN: 0002839009 *
EUR. J. MED. CHEM., vol. ２６, JPN6014026114, 1991, pages 729 - 733, ISSN: 0002839006 *
J. HETEROCYCLIC CHEM., vol. ２７, JPN6014026117, 1990, pages 1527 - 1536, ISSN: 0002839007 *
J. MED. CHEM., vol. ３０, JPN6014026119, 1987, pages 1622 - 1626, ISSN: 0002839008 *
J. MED. CHEM., vol. ３８, JPN6014026113, 1995, pages 973 - 982, ISSN: 0002839005 *
J. ORG. CHEM., vol. ７２, JPN6014026096, 2007, pages 3606 - 3607, ISSN: 0002839003 *
STEVENS K L: "SYNTHESIS AND EVALUATION OF PYRAZOLO[1,5-B]PYRIDAZINES AS SELECTIVE CYCLIN 以下備考", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. V18 N21, JPN5012012742, 1 November 2008 (2008-11-01), GB, pages 5758 - 5762, ISSN: 0002839002 *

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