JO3680B1 - تركيبات صيدلانية موضعية - Google Patents
تركيبات صيدلانية موضعيةInfo
- Publication number
- JO3680B1 JO3680B1 JOP/2016/0097A JOP20160097A JO3680B1 JO 3680 B1 JO3680 B1 JO 3680B1 JO P20160097 A JOP20160097 A JO P20160097A JO 3680 B1 JO3680 B1 JO 3680B1
- Authority
- JO
- Jordan
- Prior art keywords
- topical pharmaceutical
- skin
- pharmaceutical compositions
- patient
- relates
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
يتعلق الاختراع الحالي بتركيبات مستحلبة صيدلانية موضعية تتضمن كمية فعالة علاجياً من 3، 5- ثاني هيدروكسي-4- أيزوبروبيل-ترانس- ستيلبين أو ملح مقبول صيدلانيا منه، طور زيتي، طور مائي، منشط للسطح، ومضاد للأكسدة، وفيها التركيب المستحلب عبارة عن مستحلب متجانس أو نشط والذي يذاب في طور الزيت. ويتعلق الاختراع أيضاً بطرق لعلاج حالات جلدية أو اضطراب الجلد في مريض بإعطاء التركيبات الحالية إلى جلد المريض
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562165097P | 2015-05-21 | 2015-05-21 | |
| US201662324450P | 2016-04-19 | 2016-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO3680B1 true JO3680B1 (ar) | 2020-08-27 |
Family
ID=56081527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2016/0097A JO3680B1 (ar) | 2015-05-21 | 2016-05-19 | تركيبات صيدلانية موضعية |
Country Status (35)
| Country | Link |
|---|---|
| US (5) | US10195160B2 (ar) |
| EP (2) | EP3297605B1 (ar) |
| JP (4) | JP6863904B2 (ar) |
| KR (2) | KR20240090730A (ar) |
| CN (2) | CN114042041B (ar) |
| AU (2) | AU2016263161B2 (ar) |
| BR (1) | BR112017024934A8 (ar) |
| CA (1) | CA2986251A1 (ar) |
| CL (1) | CL2017002939A1 (ar) |
| CO (1) | CO2017011795A2 (ar) |
| CR (1) | CR20170528A (ar) |
| CY (1) | CY1125318T1 (ar) |
| DK (1) | DK3297605T3 (ar) |
| DO (1) | DOP2017000270A (ar) |
| EA (1) | EA038624B1 (ar) |
| ES (1) | ES2914112T3 (ar) |
| HR (1) | HRP20220670T1 (ar) |
| HU (1) | HUE059066T2 (ar) |
| IL (3) | IL316851A (ar) |
| JO (1) | JO3680B1 (ar) |
| LT (1) | LT3297605T (ar) |
| MX (2) | MX377629B (ar) |
| PE (1) | PE20180038A1 (ar) |
| PH (1) | PH12017502092A1 (ar) |
| PL (1) | PL3297605T3 (ar) |
| PT (1) | PT3297605T (ar) |
| RS (1) | RS63402B1 (ar) |
| SG (1) | SG11201708666RA (ar) |
| SI (1) | SI3297605T1 (ar) |
| SM (1) | SMT202200224T1 (ar) |
| TW (1) | TWI705831B (ar) |
| UA (1) | UA125500C2 (ar) |
| UY (1) | UY36682A (ar) |
| WO (1) | WO2016185428A1 (ar) |
| ZA (1) | ZA202007965B (ar) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016263161B2 (en) | 2015-05-21 | 2019-02-28 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| US11617724B2 (en) * | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
| MX2020004785A (es) | 2017-11-10 | 2020-08-13 | Dermavant Sciences GmbH | Proceso para preparar tapinarof. |
| CN109085257B (zh) * | 2018-07-05 | 2021-04-06 | 中央民族大学 | 一种同时定量检测小鼠血浆中黄芪甲苷-iv、环黄芪醇的方法 |
| MX368750B (es) * | 2018-08-31 | 2019-10-15 | Cell Therapy And Tech S A De C V | Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. |
| US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
| JP6898622B2 (ja) * | 2019-01-30 | 2021-07-07 | 学校法人神奈川大学 | 皮膚又は粘膜の外用剤及びその製造方法、並びに皮膚又は粘膜の外用剤の基剤 |
| WO2020214855A1 (en) | 2019-04-17 | 2020-10-22 | Azora Therapeutics, Inc. | Topical compositions and methods for treating inflammatory skin diseases |
| KR20220008893A (ko) * | 2019-05-15 | 2022-01-21 | 레오 파마 에이/에스 | 피부 홍반성 루푸스의 치료 |
| US20200383887A1 (en) * | 2019-06-04 | 2020-12-10 | L'oreal | Oxygenate skin treatment system |
| EP3990567A4 (en) * | 2019-06-26 | 2023-07-12 | Locus Solutions IPCo, LLC | MULTI-FUNCTIONAL COMPOSITIONS INCLUDING CONCENTRATED ACIDS FOR ENHANCED OIL AND GAS RECOVERY |
| MX2022000960A (es) * | 2019-07-24 | 2022-03-22 | Sol Gel Tech Ltd | Tratamiento de trastornos de la piel con composiciones topicas de tapinarof-inhibidor de egfr. |
| US20220387349A1 (en) * | 2019-09-26 | 2022-12-08 | Sol-Gel Technologies Ltd | Treatment of cutaneous adverse effects caused by oncological therapy with topical tapinarof compositions |
| US20220331268A1 (en) * | 2019-09-26 | 2022-10-20 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with topical combination compositions comprising tapinarof and an additional ahr activator |
| WO2021090322A1 (en) * | 2019-11-06 | 2021-05-14 | Sol-Gel Technologies Ltd. | Method of treating palmoplantar keratoderma |
| JP2023503132A (ja) * | 2019-11-24 | 2023-01-26 | ソル - ゲル テクノロジーズ リミテッド | タピナロフおよびpde4阻害剤を含む局所用組成物による皮膚障害の治療 |
| GB202000167D0 (en) * | 2020-01-07 | 2020-02-19 | Cytovation As | Composition for treatment of neoplastic lesions |
| US11154486B2 (en) | 2020-02-14 | 2021-10-26 | William M. Yarbrough Foundation | Detergent compositions for washing urushiol and methods of treating urushiol induced contact dermatitis |
| US11191708B2 (en) * | 2020-02-17 | 2021-12-07 | William M. Yarbrough Foundation | Sodium lauroyl sarcosinate containing detergent compositions |
| MX2022015792A (es) * | 2020-06-24 | 2023-02-27 | Dermavant Sciences GmbH | Composiciones farmaceuticas topicas. |
| CN115867267A (zh) * | 2020-06-30 | 2023-03-28 | 德米拉公司 | RORγt抑制剂和其局部用途 |
| US12440529B2 (en) | 2020-09-22 | 2025-10-14 | Alphyn Biologics, Inc. | Topical Croton lechleri compositions and their use in the treatment of a bacterial colonization or primary or secondary bacterial infection of an underlying skin disorder |
| CA3198952A1 (en) * | 2020-11-23 | 2022-05-27 | Dermavant Sciences GmbH | Gel, ointment, and foam formulations of tapinarof and methods of use |
| WO2022178144A1 (en) * | 2021-02-17 | 2022-08-25 | Dermavant Sciences GmbH | Remittive effects of tapinarof in the treatment of plaque psoriasis, atopic dermatitis, or radiation dermatitis |
| JP2024508454A (ja) | 2021-02-25 | 2024-02-27 | アルフィン バイオロジックス、エルエルシー | 局所皮膚細菌性皮膚疾患治療用組成物 |
| CN113797159A (zh) * | 2021-10-22 | 2021-12-17 | 冠昊生物科技股份有限公司 | 一种本维莫德乳膏剂及其制备方法和用途 |
| JP2025529076A (ja) * | 2022-08-30 | 2025-09-04 | ダーマヴァント サイエンシーズ ゲーエムベーハー | AhR媒介疾患の治療に使用するタピナロおよびそのアナログ製剤 |
| CN120475952A (zh) * | 2022-12-08 | 2025-08-12 | 发道支付有限责任公司 | 用于治疗和预防脱发和头发花白的局部组合物 |
| WO2025031935A1 (en) | 2023-08-04 | 2025-02-13 | Sandoz Ag | Crystalline forms of tapinarof |
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