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IS8619A - Ræktun mannafósturstofnfrumna - Google Patents

Ræktun mannafósturstofnfrumna

Info

Publication number
IS8619A
IS8619A IS8619A IS8619A IS8619A IS 8619 A IS8619 A IS 8619A IS 8619 A IS8619 A IS 8619A IS 8619 A IS8619 A IS 8619A IS 8619 A IS8619 A IS 8619A
Authority
IS
Iceland
Prior art keywords
cultivation
stem cells
embryonic stem
human embryonic
human
Prior art date
Application number
IS8619A
Other languages
English (en)
Inventor
A. Thomson James
Ludwig Teneille
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of IS8619A publication Critical patent/IS8619A/is

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
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    • C12N2501/80Neurotransmitters; Neurohormones
    • C12N2501/845Gamma amino butyric acid [GABA]
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IS8619A 2004-09-08 2007-03-06 Ræktun mannafósturstofnfrumna IS8619A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60804004P 2004-09-08 2004-09-08
US69510005P 2005-06-29 2005-06-29
PCT/US2005/031839 WO2006029198A2 (en) 2004-09-08 2005-09-08 Culturing human embryonic stem cells

Publications (1)

Publication Number Publication Date
IS8619A true IS8619A (is) 2007-03-06

Family

ID=35809711

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8619A IS8619A (is) 2004-09-08 2007-03-06 Ræktun mannafósturstofnfrumna

Country Status (16)

Country Link
US (2) US7442548B2 (is)
EP (2) EP1797172B1 (is)
JP (1) JP2008518585A (is)
KR (1) KR20070058584A (is)
AU (1) AU2005282414C1 (is)
BR (1) BRPI0514641A (is)
CA (1) CA2579652A1 (is)
DK (1) DK3196296T3 (is)
ES (2) ES2624586T3 (is)
GB (1) GB2432835B (is)
IL (1) IL181438A (is)
IS (1) IS8619A (is)
MX (1) MX2007002389A (is)
NO (1) NO344696B1 (is)
NZ (1) NZ553235A (is)
WO (1) WO2006029198A2 (is)

Families Citing this family (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE549395T1 (de) * 2004-09-08 2012-03-15 Wisconsin Alumni Res Found Medium und kultur von embryonalen stammzellen
ES2624586T3 (es) * 2004-09-08 2017-07-17 Wisconsin Alumni Research Foundation Cultivo de células madre embrionarias humanas
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
CN101484575B (zh) 2005-06-08 2013-10-02 森托科尔公司 用于眼变性的细胞疗法
WO2007026353A2 (en) * 2005-08-29 2007-03-08 Technion Research & Development Foundation Ltd. Media for culturing stem cells
WO2007042225A2 (en) * 2005-10-07 2007-04-19 Cellartis Ab A method for obtaining a xeno-free hbs cell line
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
GB0622394D0 (en) 2006-11-09 2006-12-20 Univ Cambridge Tech Differentiation of pluripotent cells
WO2008089351A1 (en) * 2007-01-17 2008-07-24 Wisconsin Alumni Research Foundation Improved culture of stem cells
FI20075417A0 (fi) * 2007-06-05 2007-06-05 Marjo-Riitta Suuronen Koostumuksia ja menetelmiä alkion kantasolujen kasvatukseen
AT505008B1 (de) 2007-06-06 2008-10-15 Angewandte Biotechnologie Gmbh Verfahren zum kultivieren von sehnenzellen aus nicht embryonalen pluripotenten zellen mesenchymaler herkunft
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
KR101617243B1 (ko) 2007-07-31 2016-05-02 라이프스캔, 인코포레이티드 인간 배아 줄기 세포의 분화
WO2009070592A2 (en) 2007-11-27 2009-06-04 Lifescan, Inc. Differentiation of human embryonic stem cells
CA2715878C (en) 2008-02-21 2017-06-13 Centocor Ortho Biotech Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
US9458431B2 (en) 2008-03-17 2016-10-04 Agency For Science, Technology And Research Microcarriers for stem cell culture
WO2009116951A2 (en) 2008-03-17 2009-09-24 Agency For Science, Technology And Research Microcarriers for stem cell culture
US20120028352A1 (en) * 2008-03-17 2012-02-02 Agency For Science, Technology And Research Microcarriers for Stem Cell Culture
EP2275531B1 (en) * 2008-03-31 2015-12-23 Oriental Yeast Co., Ltd. Method for proliferation of pluripotent stem cells
US8623648B2 (en) 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
DK2297307T3 (en) 2008-06-04 2016-07-25 Cellular Dynamics Int Inc PROCEDURES FOR THE MANUFACTURE OF IPS CELLS USING NON-VIRAL METHODS
KR20180018839A (ko) 2008-06-30 2018-02-21 얀센 바이오테크 인코포레이티드 만능 줄기 세포의 분화
RU2011103183A (ru) * 2008-06-30 2012-08-10 Сентокор Орто Байотек Инк. (Us) Дифференцирование плюрипотентных стволовых клеток
WO2010013845A1 (en) 2008-07-30 2010-02-04 Kyoto University Method of efficiently establishing induced pluripotent stem cells
CN107988261A (zh) 2008-08-12 2018-05-04 细胞动力国际有限公司 产生ips细胞的方法
US8648170B2 (en) 2008-09-19 2014-02-11 Wisconsin Alumni Research Foundation Peptide-presenting surfaces for long-term culture of pluripotent cells
MX349178B (es) 2008-10-31 2017-07-17 Centocor Ortho Biotech Inc Diferenciación de células madre embrionarias humanas al linaje endocrino pancreático.
CN102272291B (zh) 2008-10-31 2018-01-16 詹森生物科技公司 人胚胎干细胞向胰腺内分泌谱系的分化
US8895300B2 (en) 2008-11-04 2014-11-25 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
MX2011005288A (es) 2008-11-20 2011-06-01 Centocor Ortho Biotech Inc Celulas madre pluripotentes en microportadores.
ES2584053T3 (es) 2008-11-20 2016-09-23 Janssen Biotech, Inc. Métodos y composiciones para la unión de células y cultivo en sustratos planos
WO2010068955A2 (en) 2008-12-13 2010-06-17 Dna Microarray MICROENVIRONMENT NICHE ASSAY FOR CiPS SCREENING
JP6189581B2 (ja) 2009-02-20 2017-08-30 セルラー ダイナミクス インターナショナル, インコーポレイテッド 幹細胞の分化のための方法および組成物
US8609417B2 (en) * 2009-04-13 2013-12-17 The Regents Of The University Of California Methods and compositions for stem cell cultures
EP3150701B1 (en) 2009-06-05 2018-10-03 FUJIFILM Cellular Dynamics, Inc. Reprogramming t cells and hematopoietic cells
US20120171771A1 (en) 2009-07-08 2012-07-05 Cellular Dynamics International, Inc. Modified ips cells having a mutant form of a human immunodeficiency virus (hiv) cellular entry gene
AU2010276440B2 (en) 2009-07-20 2014-07-03 Janssen Biotech Inc. Differentiation of human embryonic stem cells
US10076544B2 (en) 2009-07-20 2018-09-18 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
CA2768720C (en) 2009-07-20 2018-12-18 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
JP5885255B2 (ja) 2009-08-28 2016-03-15 セルラー ダイナミクス インターナショナル, インコーポレイテッド 罹患組織における遺伝的変異の同定
US8415155B2 (en) 2009-10-19 2013-04-09 Cellular Dynamics International, Inc. Cardiomyocyte production
ES2665006T3 (es) * 2009-10-29 2018-04-24 Janssen Biotech, Inc. Células madre pluripotentes
EP4166652A1 (en) 2009-11-12 2023-04-19 Technion Research & Development Foundation Ltd. Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
WO2011079018A2 (en) * 2009-12-23 2011-06-30 Centocor Ortho Biotech Inc. Differentiation of human embryonic stem cells
CA2784415C (en) * 2009-12-23 2019-06-18 Jean Xu Differentiation of human embryonic stem cells
US9969981B2 (en) 2010-03-01 2018-05-15 Janssen Biotech, Inc. Methods for purifying cells derived from pluripotent stem cells
KR101903562B1 (ko) 2010-05-12 2018-10-02 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
WO2011159797A2 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
JP5984217B2 (ja) 2010-06-15 2016-09-06 セルラー ダイナミクス インターナショナル, インコーポレイテッド 少量の末梢血からの人工多能性幹細胞の作製
EP2588594B1 (en) 2010-07-01 2022-11-30 Regenerative Research Foundation Methods for culturing undifferentiated cells using sustained release compositions
JP5897002B2 (ja) 2010-07-07 2016-04-13 セルラー ダイナミクス インターナショナル, インコーポレイテッド プログラミングによる内皮細胞の産生
CA2806858C (en) 2010-08-04 2021-06-15 Cellular Dynamics International, Inc. Reprogramming immortalized b cells
RU2627168C2 (ru) 2010-08-31 2017-08-03 Янссен Байотек, Инк. Дифференцирование эмбриональных стволовых клеток человека
MX348537B (es) 2010-08-31 2017-06-07 Janssen Biotech Inc Diferencia de celulas madre pluripotentes.
RU2620938C2 (ru) 2010-08-31 2017-05-30 Янссен Байотек, Инк. Дифференцирование эмбриональных стволовых клеток человека
US9181529B2 (en) 2010-10-19 2015-11-10 Cellular Dynamics International, Inc. Titration of differentiation medium components
US9574179B2 (en) 2011-02-08 2017-02-21 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
JP6185907B2 (ja) 2011-03-30 2017-08-23 セルラー ダイナミクス インターナショナル, インコーポレイテッド 神経分化のための多能性幹細胞の予備刺激
KR101293300B1 (ko) * 2011-04-05 2013-08-09 (주)로고스바이오시스템스 세포의 분리시기를 판정하는 방법과, 이를 이용한 세포의 계대 배양 방법 및 계대 배양 장치
WO2013009825A1 (en) 2011-07-11 2013-01-17 Cellular Dynamics International, Inc. Methods for cell reprogramming and genome engineering
US8497124B2 (en) 2011-12-05 2013-07-30 Factor Bioscience Inc. Methods and products for reprogramming cells to a less differentiated state
KR102196339B1 (ko) 2011-12-05 2020-12-29 팩터 바이오사이언스 인크. 세포를 형질감염시키는 방법들 및 생성물들
CN105143446B (zh) 2011-12-22 2020-11-03 詹森生物科技公司 人胚胎干细胞分化成单一激素胰岛素阳性细胞
US9434920B2 (en) 2012-03-07 2016-09-06 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
KR102285014B1 (ko) 2012-06-08 2021-08-03 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 췌장 내분비 세포로의 분화
CN104769112A (zh) 2012-11-01 2015-07-08 菲克特生物科学股份有限公司 用于在细胞中表达蛋白质的方法和产品
RU2658488C2 (ru) 2012-12-31 2018-06-21 Янссен Байотек, Инк. Способ получения клеток, экспрессирующих маркеры, характерные для панкреатических эндокринных клеток
KR20150103203A (ko) 2012-12-31 2015-09-09 얀센 바이오테크 인코포레이티드 췌장 내분비 세포 내로의 분화를 위한 인간 만능 세포의 현탁 및 클러스터링
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
EP4219683A1 (en) 2012-12-31 2023-08-02 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators
WO2014130770A1 (en) 2013-02-22 2014-08-28 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
JP6602288B2 (ja) 2013-04-03 2019-11-06 フジフィルム セルラー ダイナミクス,インコーポレイテッド 浮遊液中で内胚葉前駆細胞を培養するための方法および組成物
AU2014256876B2 (en) 2013-04-26 2020-11-12 Cornell, University Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells
AU2015210769B2 (en) 2014-01-31 2019-02-07 Factor Bioscience Inc. Methods and products for nucleic acid production and delivery
ES2939807T3 (es) 2014-03-21 2023-04-27 Fujifilm Cellular Dynamics Inc Producción de neuronas dopaminérgicas del mesencéfalo y métodos para su utilización
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
EP3143127B1 (en) 2014-05-16 2021-07-14 Janssen Biotech, Inc. Use of small molecules to enhance mafa expression in pancreatic endocrine cells
AU2015305515B2 (en) 2014-08-19 2020-12-03 FUJIFILM Cellular Dynamics, Inc. Neural networks formed from cells derived from pluripotent stem cells
EP3207122B1 (en) 2014-10-14 2019-05-08 FUJIFILM Cellular Dynamics, Inc. Generation of keratinocytes from pluripotent stem cells and maintenance of keratinocyte cultures
US10167451B2 (en) 2014-12-22 2019-01-01 The Chinese University Of Hong Kong Combinational use of mechanical manipulation and programin derivatives to increase Oct4, Sox2, or Nanog expression in fibroblasts
EP4406585A3 (en) 2015-02-13 2024-10-23 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
CA2997952A1 (en) 2015-09-08 2017-03-16 Kapil BHARTI Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells
AU2016318774B2 (en) 2015-09-08 2022-08-18 FUJIFILM Cellular Dynamics, Inc. MACS-based purification of stem cell-derived retinal pigment epithelium
US10093903B2 (en) 2015-10-19 2018-10-09 FUJIFILM Cellular Dynamics, Inc. Production of virus-receptive pluripotent stem cell (PSC)-derived hepatocytes
KR102857712B1 (ko) 2015-10-20 2025-09-11 후지필름 셀룰러 다이내믹스, 인코포레이티드 면역 세포로의 만능 줄기 세포의 지정된 분화 방법
IL258899B2 (en) 2015-10-30 2024-03-01 Univ California Methods of generating t-cells from stem cells and immunotherapeutic methods using the t-cells
EP3397753B1 (en) 2015-12-30 2021-10-27 FUJIFILM Cellular Dynamics, Inc. Microtissue formation using stem cell-derived human hepatocytes
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
EP3456816A4 (en) * 2016-05-09 2019-12-11 Kyowa Hakko Bio Co., Ltd. MEDIUM, ADDITIVE FOR ALBUMIN-FREE MEDIUM AND METHOD FOR GROWING PLURIPOTENT STEM CELLS
CA3029582A1 (en) 2016-07-01 2018-01-04 Research Development Foundation Elimination of proliferating cells from stem cell-derived grafts
US10590383B2 (en) 2016-08-16 2020-03-17 FUJIFILM Cellular Dynamics, Inc. Methods for differentiating pluripotent cells
IL308824A (en) 2016-08-17 2024-01-01 Factor Bioscience Inc Nucleic acid products and methods of administration thereof
JP7248571B2 (ja) 2016-10-05 2023-03-29 フジフィルム セルラー ダイナミクス,インコーポレイテッド MeCP2が破壊された誘導多能性幹細胞からの成熟系列の生成
CN110891967B (zh) 2017-04-18 2025-03-14 富士胶片细胞动力公司 抗原特异性免疫效应细胞
AU2019256723B2 (en) 2018-04-20 2025-09-04 FUJIFILM Cellular Dynamics, Inc. Method for differentiation of ocular cells and use thereof
EP3883617A1 (en) 2018-11-19 2021-09-29 The United States of America, as represented by the Secretary, Department of Health and Human Services Biodegradable tissue replacement implant and its use
AU2019386140A1 (en) 2018-11-28 2021-06-24 Board Of Regents, The University Of Texas System Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
MX2021006393A (es) 2018-11-29 2021-10-13 Univ Texas Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas.
KR20220039719A (ko) 2019-07-03 2022-03-29 팩터 바이오사이언스 인크. 양이온성 지질 및 이의 용도
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
MX2022015002A (es) 2020-05-29 2023-03-03 Fujifilm Cellular Dynamics Inc Bicapa del epitelio pigmentario de la retina y fotorreceptores y uso de los mismos.
IL298085A (en) 2020-05-29 2023-01-01 Fujifilm Cellular Dynamics Inc Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof
IL302728A (en) 2020-11-13 2023-07-01 Catamaran Bio Inc Genetically modified natural killer cells and methods of use thereof
WO2022115611A1 (en) 2020-11-25 2022-06-02 Catamaran Bio, Inc. Cellular therapeutics engineered with signal modulators and methods of use thereof
EP4319876A1 (en) 2021-04-07 2024-02-14 Fujifilm Cellular Dynamics, Inc. Dopaminergic precursor cells and methods of use
US20240368541A1 (en) 2021-05-03 2024-11-07 Astellas Institute For Regenerative Medicine Methods of generating mature corneal endothelial cells
EP4334435A1 (en) 2021-05-07 2024-03-13 Astellas Institute for Regenerative Medicine Methods of generating mature hepatocytes
US20220389436A1 (en) 2021-05-26 2022-12-08 FUJIFILM Cellular Dynamics, Inc. Methods to prevent rapid silencing of genes in pluripotent stem cells
US20240271089A1 (en) 2021-05-28 2024-08-15 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Methods to generate macular, central and peripheral retinal pigment epithelial cells
WO2022251477A1 (en) 2021-05-28 2022-12-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells
CN113322225A (zh) * 2021-05-31 2021-08-31 郑州优倍得生物科技有限公司 一种人胚胎干细胞体外扩增用添加剂及扩增方法
US20230078230A1 (en) 2021-09-13 2023-03-16 FUJIFILM Cellular Dynamics, Inc. Methods for the production of committed cardiac progenitor cells
US20240034992A1 (en) 2021-10-29 2024-02-01 FUJIFILM Cellular Dynamics, Inc. Dopaminergic neurons comprising mutations and methods of use thereof
CA3259802A1 (en) 2022-06-29 2024-01-04 FUJIFILM Cellular Dynamics, Inc. IPSC-DERIVED ASTROCYTES AND THEIR METHODS OF USE
JP2025532957A (ja) 2022-09-30 2025-10-03 フジフィルム セルラー ダイナミクス,インコーポレイテッド 心臓線維芽細胞の作製方法
EP4680255A1 (en) 2023-03-16 2026-01-21 The United States of America, as represented by the Secretary, Department of Health and Human Services Methods for producing stable human chondroctyes and their use for promoting cartillage growth and repair
AU2024343386B2 (en) 2023-11-03 2025-12-18 Axent Biosciences Inc. Thermoreversible polymers with improved stability and methods and uses thereof
WO2025245202A1 (en) 2024-05-21 2025-11-27 FUJIFILM Cellular Dynamics, Inc. Particle counting and biomass measurements of aggregated cell compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7410798B2 (en) * 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
JP2005510232A (ja) * 2001-11-26 2005-04-21 アドバンスド セル テクノロジー、インク. 再プログラムされたヒト体細胞核ならびに自系および同系なヒト幹細胞の製造および使用方法
DK1572984T3 (en) * 2002-12-16 2016-06-13 Technion Res & Dev Foundation FEEDER CELL-FREE, XENOPHRIC CULTIVATION SYSTEM FOR HUMAN EMBRYONAL STEM CELLS
KR100632851B1 (ko) * 2004-01-20 2006-10-13 한국원자력연구소 전분화능 줄기세포의 분화를 억제하는 방법
ES2624586T3 (es) * 2004-09-08 2017-07-17 Wisconsin Alumni Research Foundation Cultivo de células madre embrionarias humanas
ATE549395T1 (de) * 2004-09-08 2012-03-15 Wisconsin Alumni Res Found Medium und kultur von embryonalen stammzellen

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