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IS8217A - Bætt framleiðsla rósúvastatínkalsíumsalts - Google Patents

Bætt framleiðsla rósúvastatínkalsíumsalts

Info

Publication number
IS8217A
IS8217A IS8217A IS8217A IS8217A IS 8217 A IS8217 A IS 8217A IS 8217 A IS8217 A IS 8217A IS 8217 A IS8217 A IS 8217A IS 8217 A IS8217 A IS 8217A
Authority
IS
Iceland
Prior art keywords
calcium salt
improved production
rosuvastatin calcium
rosuvastatin
production
Prior art date
Application number
IS8217A
Other languages
English (en)
Other versions
IS2751B (is
Inventor
Norman Crabb Jeffrey
Horbury John
Philip Taylor Nigel
Original Assignee
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33512687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8217(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited
Publication of IS8217A publication Critical patent/IS8217A/is
Publication of IS2751B publication Critical patent/IS2751B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS8217A 2003-06-05 2006-01-02 Bætt@framleiðsla@rósúvastatínkalsíumsalts IS2751B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0312896.4A GB0312896D0 (en) 2003-06-05 2003-06-05 Chemical process
GBGB0324793.9A GB0324793D0 (en) 2003-06-05 2003-10-24 Chemical process
PCT/GB2004/002373 WO2004108691A1 (en) 2003-06-05 2004-06-03 Improved production of rosuvastatin calcium salt

Publications (2)

Publication Number Publication Date
IS8217A true IS8217A (is) 2006-01-02
IS2751B IS2751B (is) 2011-09-15

Family

ID=33512687

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8217A IS2751B (is) 2003-06-05 2006-01-02 Bætt@framleiðsla@rósúvastatínkalsíumsalts

Country Status (25)

Country Link
US (1) US8063213B2 (is)
EP (1) EP1633727B1 (is)
JP (1) JP4651615B2 (is)
KR (1) KR101099934B1 (is)
CN (1) CN100422157C (is)
AR (1) AR044773A1 (is)
AT (1) ATE464297T1 (is)
AU (1) AU2004245291B2 (is)
BR (1) BRPI0410922B8 (is)
CA (1) CA2527314C (is)
CO (1) CO5640116A2 (is)
DE (1) DE602004026576D1 (is)
ES (1) ES2341858T3 (is)
GB (2) GB0312896D0 (is)
IL (1) IL172075A (is)
IS (1) IS2751B (is)
MX (1) MXPA05013128A (is)
MY (1) MY140820A (is)
NO (1) NO332971B1 (is)
NZ (1) NZ543962A (is)
RU (1) RU2361864C2 (is)
SA (1) SA04250223B1 (is)
TW (1) TWI341310B (is)
UY (1) UY28341A1 (is)
WO (1) WO2004108691A1 (is)

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GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
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EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
WO2004054986A2 (en) 2002-12-16 2004-07-01 Astrazeneca Uk Limited Process for the preparation of pyrimidine compounds
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
EP1737828A1 (en) * 2004-01-19 2007-01-03 Ranbaxy Laboratories Limited Amorphous magnesium salts of rosuvastatin
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
MX2007010138A (es) * 2005-02-22 2007-09-27 Teva Pharma Preparacion de rosuvastatina.
CN101203496B (zh) 2005-06-24 2011-04-20 力奇制药公司 纯的无定形瑞舒伐他汀钙的制备方法
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MX2007004423A (es) * 2005-08-16 2007-06-14 Teva Pharma Calcio de rosuvastatina con bajo contenido de sal.
BRPI0605917A2 (pt) 2005-08-16 2009-05-26 Teva Pharma intermediário cristalino de rosuvastatina
HU227696B1 (en) * 2006-04-13 2011-12-28 Egyt Gyogyszervegyeszeti Gyar Zinc salt of rosuvastatin, process for its preparation and pharmaceutical compositions containing it
EP2024341B1 (en) 2006-05-03 2015-12-02 MSN Laboratories Private Limited Novel process for statins and its pharmaceutically acceptable salts thereof
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TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process
HU230981B1 (hu) * 2007-10-12 2019-08-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás rosuvastatin só előállítására
WO2009143776A1 (zh) 2008-05-27 2009-12-03 常州制药厂有限公司 瑞舒伐他汀钙盐的制备方法及其中间体
EP2138165A1 (en) 2008-06-27 2009-12-30 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical composition comprising a statin
PL2309992T3 (pl) 2008-06-27 2018-05-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Kompozycja farmaceutyczna zawierająca statynę
US20110245285A1 (en) * 2008-09-09 2011-10-06 Biocon Limited Process for preparation of rosuvastatin acetonide calcium
EP2373609B1 (en) 2008-12-19 2013-10-16 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
EP2387561A4 (en) 2009-01-19 2012-07-25 Msn Lab Ltd IMPROVED PROCESS FOR THE PREPARATION OF HIGH-PURITY (3R, 5S) -7-β-CYCLOPROPYL-4- (4-FLUOROPHENYL) QUINOLIN-3-YL-3,5-DIHYDROXY-6 (E) -HEPTENOIC ACID, INCLUDING ITS PHARMACEUTICALLY ACCEPTABLE SALTS
WO2011086584A2 (en) 2010-01-18 2011-07-21 Msn Laboratories Limited Improved process for the preparation of amide intermediates and their use thereof
WO2011132172A1 (en) 2010-04-23 2011-10-27 Ranbaxy Laboratories Limited NOVEL INTERMEDIATES FOR THE PREPARATION OF HMG-CoA REDUCTASE INHIBITORS
WO2012011129A2 (en) * 2010-07-22 2012-01-26 Msn Laboratories Limited Novel polymorph of bis[(e)-7-[4-(4-fluorophenyl)-6-iso-propyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid] calcium salt
CN105753834B (zh) * 2016-03-25 2018-08-21 河南师范大学 一种瑞舒伐他汀钙关键手性中间体的合成方法

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Also Published As

Publication number Publication date
RU2361864C2 (ru) 2009-07-20
NZ543962A (en) 2008-09-26
KR101099934B1 (ko) 2011-12-28
MY140820A (en) 2010-01-29
TW200510337A (en) 2005-03-16
ATE464297T1 (de) 2010-04-15
WO2004108691A1 (en) 2004-12-16
DE602004026576D1 (de) 2010-05-27
CN1798741A (zh) 2006-07-05
HK1087405A1 (en) 2006-10-13
CA2527314A1 (en) 2004-12-16
NO20055730D0 (no) 2005-12-05
AR044773A1 (es) 2005-10-05
JP2006526602A (ja) 2006-11-24
BRPI0410922B8 (pt) 2021-05-25
EP1633727A1 (en) 2006-03-15
US20080221323A1 (en) 2008-09-11
BRPI0410922A (pt) 2006-06-27
AU2004245291A1 (en) 2004-12-16
NO20055730L (no) 2005-12-27
NO332971B1 (no) 2013-02-11
BRPI0410922B1 (pt) 2016-02-23
JP4651615B2 (ja) 2011-03-16
CO5640116A2 (es) 2006-05-31
CN100422157C (zh) 2008-10-01
IS2751B (is) 2011-09-15
RU2005138370A (ru) 2006-07-10
UY28341A1 (es) 2005-01-31
ES2341858T3 (es) 2010-06-29
GB0312896D0 (en) 2003-07-09
TWI341310B (en) 2011-05-01
SA04250223B1 (ar) 2008-12-23
KR20060017848A (ko) 2006-02-27
EP1633727B1 (en) 2010-04-14
MXPA05013128A (es) 2006-03-16
AU2004245291B2 (en) 2008-02-14
CA2527314C (en) 2012-02-21
IL172075A (en) 2011-06-30
GB0324793D0 (en) 2003-11-26
US8063213B2 (en) 2011-11-22

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