IS7079A - Fenýlsúlfónýl-1,3-díhýdró-2H-indól-2-ón afleiður,framleiðsla þeirra og notkun í meðferðarskyni - Google Patents

Fenýlsúlfónýl-1,3-díhýdró-2H-indól-2-ón afleiður,framleiðsla þeirra og notkun í meðferðarskyni

Info

Publication number: IS7079A
Authority: IS; Iceland
Prior art keywords: phenylsulfonyl; indol; dihydro; derivatives; preparation
Prior art date: 2001-07-17

Application number

IS7079A

Other languages

English (en)

Other versions

IS2485B (is

Inventor

Di Malta Alain

Garcia Georges

Roux Richard

Schoentjes Bruno

Serradeil-Le Gal Claudine

Tonnerre Bernard

Wagnon Jean

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-17

Filing date

2003-12-15

Publication date

2003-12-15

2003-12-15 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

2003-12-15 Publication of IS7079A publication Critical patent/IS7079A/is

2008-12-15 Publication of IS2485B publication Critical patent/IS2485B/is

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
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Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Hematology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)

IS7079A 2001-07-17 2003-12-15 Fenýlsúlfónýl-1,3-díhýdró-2H-indól-2-ón afleiður,framleiðsla þeirra og notkun í meðferðarskyni IS2485B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0110359A FR2827604B1 (fr)	2001-07-17	2001-07-17	Nouveaux derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2- one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
PCT/FR2002/002500 WO2003008407A2 (fr)	2001-07-17	2002-07-15	Derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique

Publications (2)

Publication Number	Publication Date
IS7079A true IS7079A (is)	2003-12-15
IS2485B IS2485B (is)	2008-12-15

Family

ID=8866211

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7079A IS2485B (is)	2001-07-17	2003-12-15	Fenýlsúlfónýl-1,3-díhýdró-2H-indól-2-ón afleiður,framleiðsla þeirra og notkun í meðferðarskyni

Country Status (31)

Country	Link
US (1)	US7119086B2 (is)
EP (1)	EP1419150B1 (is)
JP (1)	JP4262088B2 (is)
KR (1)	KR20040017325A (is)
CN (1)	CN1224623C (is)
AR (1)	AR034792A1 (is)
AT (1)	ATE294171T1 (is)
AU (1)	AU2002340999B2 (is)
BR (1)	BR0211284A (is)
CA (1)	CA2450437A1 (is)
CO (1)	CO5550440A2 (is)
DE (1)	DE60203917T2 (is)
DK (1)	DK1419150T3 (is)
EA (1)	EA006019B1 (is)
ES (1)	ES2240814T3 (is)
FR (1)	FR2827604B1 (is)
HR (1)	HRP20040027A2 (is)
HU (1)	HUP0401461A3 (is)
IL (1)	IL159275A0 (is)
IS (1)	IS2485B (is)
MA (1)	MA27049A1 (is)
ME (1)	MEP24508A (is)
MX (1)	MXPA04000507A (is)
NO (1)	NO20040219L (is)
NZ (1)	NZ530144A (is)
PL (1)	PL366829A1 (is)
PT (1)	PT1419150E (is)
RS (1)	RS204A (is)
UA (1)	UA77181C2 (is)
WO (1)	WO2003008407A2 (is)
ZA (1)	ZA200309717B (is)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7754711B2 (en) *	2003-07-30	2010-07-13	Xenon Pharmaceuticals Inc.	Pyridazine derivatives and their use as therapeutic agents
RU2259999C2 (ru) *	2003-08-26	2005-09-10	ООО "Исследовательский институт химического разнообразия"	1-сульфонил-1,3-дигидроиндол-2-оны, фармацевтические композиции (варианты), способ их получения и применения
WO2005018531A2 (en) *	2003-08-26	2005-03-03	'chemical Diversity Research Institute', Ltd.	Pharmaceutical compositions, azo-heterocyclic compounds and method for the production and use thereof
EP1659121A4 (en)	2003-08-28	2008-11-26	Taisho Pharmaceutical Co Ltd	1,3-dihydro-2H-indol-2-one derivative
US20050070718A1 (en) *	2003-09-30	2005-03-31	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US8580842B2 (en) *	2003-09-30	2013-11-12	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
BRPI0510260A (pt)	2004-04-27	2007-10-23	Wyeth Corp	método para purificar um composto, e, kit farmacêutico
DE102004033834A1 (de) *	2004-07-13	2006-02-02	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate und diese enthaltende Arzneimittel
WO2006070742A1 (ja) *	2004-12-27	2006-07-06	Kyoto University	麻薬性鎮痛剤の耐性形成抑制剤
WO2006080574A1 (ja) *	2005-01-28	2006-08-03	Taisho Pharmaceutical Co., Ltd.	１，３－ジヒドロ－２ｈ－インドール－２－オン化合物、及び芳香族複素環が縮合したピロリジン－２－オン化合物
EP1861392A2 (de)	2005-03-24	2007-12-05	Abbott GmbH & Co. KG	Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
DE102005014936A1 (de) *	2005-03-24	2006-12-14	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
DE102005014904A1 (de) *	2005-03-26	2007-02-01	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
US7576082B2 (en)	2005-06-24	2009-08-18	Hoffman-La Roche Inc.	Oxindole derivatives
SG132540A1 (en)	2005-11-25	2007-06-28	Matsushita Electric Industrial Co Ltd	Magnetic trap for ferrous contaminants in lubricant
WO2007063123A1 (de)	2005-12-02	2007-06-07	Abbott Gmbh & Co. Kg	Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
DE102006040915A1 (de) *	2006-08-26	2008-03-20	Abbott Gmbh & Co. Kg	Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
TWI403508B (zh) *	2006-08-26	2013-08-01	Abbott Gmbh & Co Kg	經取代苯并咪唑酮衍生物、包含其之醫藥品及其用途
US8486979B2 (en)	2006-12-12	2013-07-16	Abbvie Inc.	1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) *	2006-12-12	2008-07-10	Abbott Laboratories	Pharmaceutical compositions and their methods of use
UY30846A1 (es)	2006-12-30	2008-07-31	Abbott Gmbh & Amp	Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
CN101611028B (zh) *	2006-12-30	2013-09-11	艾博特股份有限两合公司	取代的羟吲哚衍生物、以及它们用作加压素受体配体的用途
US8486931B2 (en) *	2007-03-02	2013-07-16	Abbott Gmbh & Co. Kg	Substituted oxindole compounds
FR2920023B1 (fr) *	2007-08-16	2013-02-08	Sanofi Aventis	Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique
EP2231644B1 (de) *	2007-12-07	2014-01-15	AbbVie Deutschland GmbH & Co KG	5,6-Disubstitutierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen
WO2009071691A2 (de) *	2007-12-07	2009-06-11	Abbott Gmbh & Co. Kg	Oxindol-derivate und ihre verwendung als medikament
EP2231643B1 (de)	2007-12-07	2012-10-31	Abbott GmbH & Co. KG	Amidomethyl-substitutierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen
US8703774B2 (en)	2007-12-07	2014-04-22	AbbVie Deutschland GmbH & Co. KG	Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
CN101952276B (zh)	2007-12-07	2014-10-22	Abbvie德国有限责任两合公司	5-卤素取代的羟吲哚衍生物和其用于治疗加压素依赖性疾病的用途
CN106146469A (zh)	2007-12-27	2016-11-23	Abbvie德国有限责任两合公司	取代的羟吲哚衍生物及其用于治疗加压素依赖性疾病的应用
FR2927625B1 (fr)	2008-02-19	2010-03-12	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique
FR2930249B1 (fr) *	2008-04-21	2010-05-14	Sanofi Aventis	Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.
WO2010017827A1 (en) *	2008-08-14	2010-02-18	European Molecular Biology Laboratory	6-substituted 1-sulfonyl-2, 3-dihydro-indole derivatives for the treatment of proliferative diseases
DK2349324T3 (en)	2008-10-17	2017-12-11	Sanofi Aventis Deutschland	COMBINATION OF AN INSULIN AND A GLP-1 AGONIST
FR2941947B1 (fr)	2009-02-12	2011-03-25	Sanofi Aventis	Derives de 3-benzofuranyl-indol-2-one subtitues en 3, leur preparation et leur application en therapeutique
FR2941946B1 (fr)	2009-02-12	2011-03-25	Sanofi Aventis	Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique
US9040568B2 (en)	2009-05-29	2015-05-26	Abbvie Inc.	Pharmaceutical compositions for the treatment of pain
EP2440202A1 (en) *	2009-06-10	2012-04-18	Abbott GmbH & Co. KG	Use of substituted oxindole derivatives for the treatment and prophylaxis of pain
ES2965209T3 (es)	2009-11-13	2024-04-11	Sanofi Aventis Deutschland	Composición farmacéutica que comprende desPro36exendina-4(1-39)-Lys6-NH2 y metionina
KR101836070B1 (ko)	2009-11-13	2018-03-09	사노피-아벤티스 도이칠란트 게엠베하	Ｇｌｐ－１ 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물
US8088815B2 (en)	2009-12-02	2012-01-03	Hoffman-La Roche Inc.	Spiroindolinone pyrrolidines
US8288431B2 (en)	2010-02-17	2012-10-16	Hoffmann-La Roche Inc.	Substituted spiroindolinones
US8217044B2 (en)	2010-04-28	2012-07-10	Hoffmann-La Roche Inc.	Spiroindolinone pyrrolidines
AU2011202239C1 (en)	2010-05-19	2017-03-16	Sanofi	Long-acting formulations of insulins
CN103179978A (zh)	2010-08-30	2013-06-26	赛诺菲-安万特德国有限公司	Ave0010用于制造供治疗2型糖尿病用的药物的用途
CN103380127B (zh)	2010-12-21	2016-08-10	拜耳知识产权有限责任公司	制备n-磺酰基取代的羟吲哚的方法
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ES2550357T3 (es)	2011-08-29	2015-11-06	Sanofi-Aventis Deutschland Gmbh	Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2
TWI559929B (en)	2011-09-01	2016-12-01	Sanofi Aventis Deutschland	Pharmaceutical composition for use in the treatment of a neurodegenerative disease
UA117480C2 (uk)	2013-04-03	2018-08-10	Санофі	Лікування цукрового діабету за допомогою складу інсуліну тривалої дії
HRP20230470T1 (hr)	2014-12-12	2023-07-21	Sanofi-Aventis Deutschland Gmbh	Formulacija fiksnog omjera inzulin glargin/liksisenatid
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
EP3912625A1 (en) *	2020-05-20	2021-11-24	Kaerus Bioscience Limited	Novel maxi-k potassium channel openers for the treatment of fragile x associated disorders
KR20230090589A (ko) *	2021-12-15	2023-06-22	국립해양생물자원관	성게 유래 펩타이드 및 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2714378B1 (fr) *	1993-12-24	1996-03-15	Sanofi Sa	Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant.
GB2326639A (en) *	1997-06-18	1998-12-30	Merck & Co Inc	Piperazine Oxytocin Receptor Antagonists
US20050070718A1 (en) *	2003-09-30	2005-03-31	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them

2001
- 2001-07-17 FR FR0110359A patent/FR2827604B1/fr not_active Expired - Fee Related
2002
- 2002-07-15 WO PCT/FR2002/002500 patent/WO2003008407A2/fr not_active Ceased
- 2002-07-15 AT AT02774822T patent/ATE294171T1/de active
- 2002-07-15 EA EA200301306A patent/EA006019B1/ru not_active IP Right Cessation
- 2002-07-15 DK DK02774822T patent/DK1419150T3/da active
- 2002-07-15 CA CA002450437A patent/CA2450437A1/en not_active Abandoned
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- 2002-07-15 KR KR10-2004-7000787A patent/KR20040017325A/ko not_active Abandoned
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- 2004-01-14 CO CO04002002A patent/CO5550440A2/es not_active Application Discontinuation
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Also Published As

Publication number	Publication date
DE60203917D1 (de)	2005-06-02
AU2002340999B2 (en)	2007-03-01
CO5550440A2 (es)	2005-08-31
JP2004536131A (ja)	2004-12-02
HK1061679A1 (en)	2004-09-30
WO2003008407A2 (fr)	2003-01-30
BR0211284A (pt)	2004-08-03
HUP0401461A3 (en)	2009-06-29
MXPA04000507A (es)	2004-07-23
JP4262088B2 (ja)	2009-05-13
RS204A (sr)	2006-12-15
HUP0401461A2 (hu)	2004-12-28
MEP24508A (en)	2010-10-10
IS2485B (is)	2008-12-15
CA2450437A1 (en)	2003-01-30
DE60203917T2 (de)	2006-02-16
AR034792A1 (es)	2004-03-17
EP1419150A2 (fr)	2004-05-19
CN1533387A (zh)	2004-09-29
US20040180878A1 (en)	2004-09-16
FR2827604A1 (fr)	2003-01-24
HRP20040027A2 (en)	2004-06-30
EA006019B1 (ru)	2005-08-25
ZA200309717B (en)	2004-12-15
KR20040017325A (ko)	2004-02-26
WO2003008407A3 (fr)	2003-10-16
NZ530144A (en)	2005-03-24
US7119086B2 (en)	2006-10-10
ES2240814T3 (es)	2005-10-16
DK1419150T3 (da)	2005-08-29
ATE294171T1 (de)	2005-05-15
PL366829A1 (en)	2005-02-07
PT1419150E (pt)	2005-08-31
EP1419150B1 (fr)	2005-04-27
CN1224623C (zh)	2005-10-26
NO20040219L (no)	2004-03-17
UA77181C2 (en)	2006-11-15
IL159275A0 (en)	2004-06-01
EA200301306A1 (ru)	2004-06-24
MA27049A1 (fr)	2004-12-20
FR2827604B1 (fr)	2003-09-19

Publication	Publication Date	Title
IS7079A (is)	2003-12-15	Fenýlsúlfónýl-1,3-díhýdró-2H-indól-2-ón afleiður,framleiðsla þeirra og notkun í meðferðarskyni
NO20012567D0 (no)	2001-05-25	Azepinoindolderivater, fremstilling og anvendelse derav
IS6661A (is)	2002-12-19	Bensimídasólafleiður, framleiðsla þeirra og meðferðarleg notkun
NO20035298D0 (no)	2003-11-28	CDK-inhiberende pyrimider, deres fremstilling og deres anvendelse som legemidler
IS2458B (is)	2008-11-15	Indólín-2-ón afleiður, framleiðsla og notkun þeirra sem mjaltavaka (ocytocin) viðtakabindlar
EE200300311A (et)	2003-10-15	Ftalasinoon-piperidinoderivaadid, nende kasutamine ja ravim
DK1161434T3 (da)	2003-05-26	Pyridopyranoazepinderivater, deres fremstilling og terapeutiske anvendelse
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DK1513836T3 (da)	2006-09-11	Piperazinylacylpiperidinderivater, fremstilling og terapeutisk anvendelse heraf
DK1590321T3 (da)	2010-08-09	Arylalkylcarbamat-derivater, fremstilling og terapeutisk anvendelse deraf
NO20031838D0 (no)	2003-04-24	Benzokazinonderivater, deres fremstilling og anvendelse
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DK1525193T3 (da)	2008-04-28	Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse
DK1043307T3 (da)	2003-09-22	3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
DK1387838T3 (da)	2006-08-14	Cyanoanthranylamid-derivater og deres anvendelse som lægemidler
DK1556382T3 (da)	2008-10-06	3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf
NO20033120D0 (no)	2003-07-08	2-arylimino-2,3-dihydrotiazolderivater, fremgangsmater for fremstilling derav og terapeutisk anvendelse derav
NO20024107L (no)	2002-09-27	Tienopyridin derivater, deres fremstilling og anvendelse
IS2487B (is)	2008-12-15	Asýloxýpýrrólidín afleiður, framleiðsla og meðferðarnotkun þar á
NO20001782L (no)	2000-10-09	3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
NO20033965D0 (no)	2003-09-08	Caloporosidderivater, fremgangsmåte for deres fremstilling og deres anvendelse
DK1458721T3 (da)	2007-03-26	3-heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino[4,5-b]indol-1-carbox-amidderivater, deres fremstilling og terapeutisk anvendelse
IS6391A (is)	2002-05-21	2-Arýlkínólín afleiður, framleiðsla og meðferðarleg notkun á þeim
DK1309594T3 (da)	2005-04-25	Benzimidazolderivater, fremstilling heraf og terapeutisk anvendelse heraf
NO20033118D0 (no)	2003-07-08	Mikanolide-derivater, deres fremstilling og terapeutiske anvendelser