IS5329A - Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðar - Google Patents
Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðarInfo
- Publication number
- IS5329A IS5329A IS5329A IS5329A IS5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A IS 5329 A IS5329 A IS 5329A
- Authority
- IS
- Iceland
- Prior art keywords
- adjuvant
- monoglyceride
- transport system
- antigen
- antigen transport
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- -1 are described Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cultivation Of Plants (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
| PCT/IS1998/000006 WO1999002186A2 (en) | 1997-07-09 | 1998-07-09 | Antigen delivery system comprising monoglyceride or diglyceride derivatives as adjuvant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS5329A true IS5329A (is) | 1999-12-29 |
Family
ID=36699745
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
| IS5329A IS5329A (is) | 1997-07-09 | 1999-12-29 | Flutningskerfi fyrir antígen þar sem monoglýseríðeða díglýseríð afleiður eru ónæmisglæðar |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4518A IS4518A (is) | 1997-07-09 | 1997-07-09 | Nýtt lyfjaform fyrir bóluefni |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6514503B1 (is) |
| EP (1) | EP1003551B1 (is) |
| JP (1) | JP2001509491A (is) |
| KR (1) | KR20010021622A (is) |
| CN (1) | CN1202863C (is) |
| AT (1) | ATE329617T1 (is) |
| AU (1) | AU745849B2 (is) |
| BR (1) | BR9810568A (is) |
| CA (1) | CA2295237A1 (is) |
| DE (1) | DE69834921T2 (is) |
| ES (1) | ES2267189T3 (is) |
| IS (2) | IS4518A (is) |
| WO (1) | WO1999002186A2 (is) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| HU225844B1 (en) * | 1998-05-07 | 2007-10-29 | Corixa Corp | Adjuvant composition and its use |
| ES2367625T3 (es) | 1999-05-13 | 2011-11-07 | Wyeth Holdings Corporation | Formulaciones de combinaciones de adyuvantes. |
| WO2001012222A1 (en) * | 1999-08-18 | 2001-02-22 | Kim Ho Youn | Immunological tolerance-induction agent |
| US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
| GB0007465D0 (en) * | 2000-03-29 | 2000-05-17 | Amersham Pharm Biotech Uk Ltd | Substrate for a lipase enzyme assay |
| CA2409406C (en) * | 2000-06-22 | 2010-09-14 | American Cyanamid Company | Qs-21 and il-12 as an adjuvant combination |
| NZ525887A (en) * | 2000-11-10 | 2005-08-26 | Wyeth Corp | Adjuvant combination formulations |
| CN1297316C (zh) * | 2001-06-07 | 2007-01-31 | 惠氏控股有限公司 | 作为佐剂的霍乱全毒素的突变体形式 |
| EP1404279A4 (en) * | 2001-06-07 | 2007-08-08 | Wyeth Corp | MUTANT FORMS OF CHOLERA HOLOTOXIN AS ADJUVANT |
| US20040241310A1 (en) * | 2001-08-16 | 2004-12-02 | Sveibjorn Gizurarson | Method of producing antibodies ex-vivo |
| WO2003047493A2 (en) * | 2001-12-03 | 2003-06-12 | Dor Biopharma Inc. | Stabilized reverse micelle compositions and uses thereof |
| CN1642576A (zh) * | 2002-02-25 | 2005-07-20 | 药物发展有限公司 | 吸收增强剂 |
| EP1476183A1 (en) * | 2002-02-25 | 2004-11-17 | Lyfjathroun HF, Biopharmaceutical Research | An immunological adjuvant |
| US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
| EP1566621A4 (en) * | 2002-11-21 | 2010-04-07 | Sapporo Immuno Diagnostic Lab | INSTRUMENT FOR COLLECTING AND RECOVERING SALIVE |
| WO2004056314A2 (en) * | 2002-12-17 | 2004-07-08 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of y2 receptor-binding peptides and methods for treating and preventing obesity |
| US8685718B2 (en) * | 2003-05-20 | 2014-04-01 | New York University | Mucosal immunization to prevent prion infection |
| WO2005019412A2 (en) | 2003-05-20 | 2005-03-03 | New York University | Mucosal immunization to prevent prion infection |
| US20060264505A1 (en) * | 2003-11-07 | 2006-11-23 | Stiefel Laboratories, Inc. | Dermatological compositions |
| US20050100621A1 (en) * | 2003-11-07 | 2005-05-12 | Popp Karl F. | Dermatological compositions |
| WO2005046721A2 (en) * | 2003-11-10 | 2005-05-26 | Uab Research Foundation | Compositions for reducing bacterial carriage and cns invasion and methods of using same |
| EP1917976B1 (en) | 2005-08-01 | 2011-03-16 | Hisamitsu Pharmaceutical Co. Inc. | Adjuvant or pharmaceutical preparation for transdermal or transmucosal administration |
| KR101523108B1 (ko) * | 2006-08-17 | 2015-05-26 | 더 유에이비 리서치 파운데이션 | 면역원성 pcpa 폴리펩티드 및 이의 용도 |
| EP2123296B1 (en) * | 2007-01-31 | 2019-05-22 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant for transdermal or transmucosal administration and pharmaceutical preparation containing the same |
| WO2008143676A1 (en) * | 2007-05-23 | 2008-11-27 | The Uab Research Foundation | Detoxified pneumococcal neuraminidase and uses thereof |
| JP2012505197A (ja) * | 2008-10-08 | 2012-03-01 | イミューン・ソリューションズ・リミテッド | 粘膜免疫を生成するための経口ワクチン |
| ES2720872T3 (es) * | 2009-03-11 | 2019-07-25 | Monsanto Technology Llc | Formulaciones herbicidas que comprenden glifosato y glicéridos alcoxilados |
| US9603919B2 (en) * | 2009-03-31 | 2017-03-28 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Method for prophylaxis of influenza using vaccine for intranasal administration |
| ES2625406T3 (es) | 2010-03-25 | 2017-07-19 | Oregon Health & Science University | Glicoproteínas de CMV y vectores recombinantes |
| WO2012170765A2 (en) | 2011-06-10 | 2012-12-13 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9993549B2 (en) | 2013-10-31 | 2018-06-12 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant composition, adjuvant preparation containing same, and kit |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| CU24534B1 (es) * | 2017-11-06 | 2021-07-02 | Ct Inmunologia Molecular | Adyuvantes nano-particulados que contienen variantes sintéticas del gangliósido gm3 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE545978A (is) * | 1955-03-11 | |||
| FR2253499B1 (is) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
| US4420484A (en) * | 1979-08-13 | 1983-12-13 | Sterling Drug Inc. | Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof |
| DE3225706C2 (de) * | 1982-07-09 | 1984-04-26 | A. Nattermann & Cie GmbH, 5000 Köln | Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen |
| JPS60149510A (ja) | 1984-01-13 | 1985-08-07 | Kao Corp | 農薬組成物 |
| US4610868A (en) | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
| US4771571A (en) * | 1986-12-31 | 1988-09-20 | Nabisco Brands, Inc. | Method for treating pineapple to prevent pineapple fruit diseases |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| EP0324455A3 (en) * | 1988-01-15 | 1991-03-27 | Hans O. Ribi | Novel polymeric immunological adjuvants |
| US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
| US5177091A (en) * | 1990-12-06 | 1993-01-05 | Ciba-Geigy Corporation | Use of carbazones as novel active ingredients in medicaments |
| GEP20033082B (en) * | 1991-03-15 | 2003-10-27 | Amgen Inc | Pegylation of Polypeptides |
| JPH06507172A (ja) * | 1991-04-19 | 1994-08-11 | アフィニティー バイオテック,インコーポレイテッド | 転換可能なミクロエマルジョン処方剤 |
| CA2083553A1 (en) | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
| GB9207799D0 (en) | 1992-04-09 | 1992-05-27 | Procter & Gamble | Aqueous compositions |
| US5314685A (en) * | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
| DE69329430T2 (de) * | 1992-10-16 | 2001-05-10 | Ibah, Inc. | Konvertierbare mikroemulsionsformulierungen |
| IT1255895B (it) * | 1992-10-20 | 1995-11-17 | Laura Chiodini | Composizioni farmaceutiche contenenti una calcitonina |
| CA2153780C (en) | 1993-01-15 | 2004-04-13 | Micro Vesicular Systems, Inc. | Method of inhibiting viral reproduction |
| DK17093D0 (da) * | 1993-02-15 | 1993-02-15 | Lyfjathroun H F | Farmaceutisk praeparat til topisk administrering af antigener og/eller vacciner til pattedyr via slimhinder |
| US5359030A (en) * | 1993-05-10 | 1994-10-25 | Protein Delivery, Inc. | Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| ES2141950T3 (es) * | 1994-08-05 | 2000-04-01 | Inpharma Sa | Composiciones que contienen troxerutina complejada con fosfatidilcolina para el tratamiento topico de la impotencia erectil. |
| FR2729307B1 (fr) * | 1995-01-18 | 1997-04-18 | Seppic Sa | Utilisation d'esters d'acides gras ethoxyles comme composants auto-emulsionnables notamment utiles pour la preparation de produits de traitement phytosanitaires ou de medicaments a usage veterinaire ou humain |
| US5744137A (en) * | 1995-02-06 | 1998-04-28 | The United States Of America As Represented By The Secretary Of The Agriculture | Oil emulsion vaccines prepared with animal, vegetable, and synthetic oils using a mixture of nonionic surfactants |
| US6008228A (en) * | 1995-06-06 | 1999-12-28 | Hoffman-La Roche Inc. | Pharmaceutical compositions containing proteinase inhibitors |
| ES2168481T3 (es) * | 1995-06-09 | 2002-06-16 | Scherer Technologies Inc R P | Capsulas de gelatina blanda conteniendo un material en particulas. |
| EP0781559B1 (en) * | 1995-11-30 | 2007-02-07 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Oil adjuvant vaccine and method for preparing same |
| SE9602280D0 (sv) * | 1996-06-10 | 1996-06-10 | Pharmatrix Ab | Immunstimulerande lipidformulering |
| ATE226078T1 (de) * | 1996-08-26 | 2002-11-15 | Takeda Chemical Industries Ltd | Pharmazeutische zusammensetzung enthaltend ein osteogenese foerderndes mittel und ein polyethylen-glycol |
| IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| FR2773489B1 (fr) * | 1998-01-15 | 2001-03-23 | Immunotech Sa | Nouvelle composition destinee a la voie oromuqueuse notamment pernasale |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| EP1034792A1 (en) * | 1999-03-11 | 2000-09-13 | Pasteur Merieux Serums Et Vaccins | Intranasal delivery of pneumococcal polysaccharide vaccines |
| US6458383B2 (en) * | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
| US6468559B1 (en) * | 2000-04-28 | 2002-10-22 | Lipocine, Inc. | Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods |
| US6495596B1 (en) * | 2001-03-23 | 2002-12-17 | Biozibe Laboratories, Inc. | Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2 |
| US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
-
1997
- 1997-07-09 IS IS4518A patent/IS4518A/is unknown
-
1998
- 1998-07-09 CN CNB988069660A patent/CN1202863C/zh not_active Expired - Fee Related
- 1998-07-09 AU AU84598/98A patent/AU745849B2/en not_active Ceased
- 1998-07-09 ES ES98935262T patent/ES2267189T3/es not_active Expired - Lifetime
- 1998-07-09 US US09/112,684 patent/US6514503B1/en not_active Expired - Fee Related
- 1998-07-09 JP JP2000501776A patent/JP2001509491A/ja active Pending
- 1998-07-09 EP EP98935262A patent/EP1003551B1/en not_active Expired - Lifetime
- 1998-07-09 CA CA002295237A patent/CA2295237A1/en not_active Abandoned
- 1998-07-09 DE DE69834921T patent/DE69834921T2/de not_active Expired - Fee Related
- 1998-07-09 AT AT98935262T patent/ATE329617T1/de not_active IP Right Cessation
- 1998-07-09 KR KR1020007000180A patent/KR20010021622A/ko not_active Ceased
- 1998-07-09 WO PCT/IS1998/000006 patent/WO1999002186A2/en not_active Ceased
- 1998-07-09 BR BR9810568-0A patent/BR9810568A/pt not_active Application Discontinuation
-
1999
- 1999-12-29 IS IS5329A patent/IS5329A/is unknown
-
2002
- 2002-07-12 US US10/195,226 patent/US20030099659A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU8459898A (en) | 1999-02-08 |
| ATE329617T1 (de) | 2006-07-15 |
| CA2295237A1 (en) | 1999-01-21 |
| CN1262626A (zh) | 2000-08-09 |
| IS4518A (is) | 1999-01-10 |
| EP1003551B1 (en) | 2006-06-14 |
| WO1999002186A3 (en) | 1999-04-01 |
| KR20010021622A (ko) | 2001-03-15 |
| JP2001509491A (ja) | 2001-07-24 |
| DE69834921D1 (de) | 2006-07-27 |
| WO1999002186A2 (en) | 1999-01-21 |
| CN1202863C (zh) | 2005-05-25 |
| DE69834921T2 (de) | 2007-01-18 |
| US6514503B1 (en) | 2003-02-04 |
| BR9810568A (pt) | 2000-09-19 |
| ES2267189T3 (es) | 2007-03-01 |
| US20030099659A1 (en) | 2003-05-29 |
| EP1003551A2 (en) | 2000-05-31 |
| AU745849B2 (en) | 2002-04-11 |
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