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IS4562A - Glýkósamstæður, lyf sem innihalda þær, og notkun glýkósamstæðnanna við framleiðslu lyfja - Google Patents

Glýkósamstæður, lyf sem innihalda þær, og notkun glýkósamstæðnanna við framleiðslu lyfja

Info

Publication number
IS4562A
IS4562A IS4562A IS4562A IS4562A IS 4562 A IS4562 A IS 4562A IS 4562 A IS4562 A IS 4562A IS 4562 A IS4562 A IS 4562A IS 4562 A IS4562 A IS 4562A
Authority
IS
Iceland
Prior art keywords
glycosides
drugs
manufacture
drugs containing
cytostatics
Prior art date
Application number
IS4562A
Other languages
English (en)
Other versions
IS1822B (is
Inventor
Lerchen Hans-Georg
Von Dem Bruch Karsten
Petersen Uwe
Baumgarten Jörg
Piel Norbert
Antonicek Horst-Peter
Weichel Walter
Sperzel Michael
Dieter Bremm Klaus
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of IS4562A publication Critical patent/IS4562A/is
Publication of IS1822B publication Critical patent/IS1822B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
IS4562A 1995-04-04 1997-09-18 Glýkósamstæður, lyf sem innihalda þær, og notkun glýkósamstæðnanna við framleiðslu lyfja IS1822B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19512484A DE19512484A1 (de) 1995-04-04 1995-04-04 Kohlenhydratmodifizierte Cytostatika
PCT/EP1996/001279 WO1996031532A1 (de) 1995-04-04 1996-03-22 Kohlenhydratmodifizierte cytostatika

Publications (2)

Publication Number Publication Date
IS4562A true IS4562A (is) 1997-09-18
IS1822B IS1822B (is) 2002-10-01

Family

ID=7758679

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4562A IS1822B (is) 1995-04-04 1997-09-18 Glýkósamstæður, lyf sem innihalda þær, og notkun glýkósamstæðnanna við framleiðslu lyfja

Country Status (27)

Country Link
US (1) US6271342B1 (is)
EP (1) EP0819135B1 (is)
JP (1) JPH11502860A (is)
KR (1) KR19980703591A (is)
CN (1) CN1185786A (is)
AT (1) ATE186738T1 (is)
AU (1) AU713466B2 (is)
BG (1) BG63048B1 (is)
BR (1) BR9604825A (is)
CA (1) CA2217164A1 (is)
CZ (1) CZ291098B6 (is)
DE (2) DE19512484A1 (is)
DK (1) DK0819135T3 (is)
EE (1) EE03619B1 (is)
ES (1) ES2140078T3 (is)
GR (1) GR3032605T3 (is)
HU (1) HUP9800513A3 (is)
IS (1) IS1822B (is)
MX (1) MX9707613A (is)
NO (1) NO974564L (is)
NZ (1) NZ305855A (is)
PL (1) PL183574B1 (is)
RU (1) RU2170234C2 (is)
SK (1) SK281785B6 (is)
TW (1) TW384290B (is)
UA (1) UA61054C2 (is)
WO (1) WO1996031532A1 (is)

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JP2001504453A (ja) * 1996-09-30 2001-04-03 バイエル・アクチエンゲゼルシヤフト 改変カンプトテシン誘導体からの複合糖質（２０―ｏ―結合）
DE19640970A1 (de) * 1996-10-04 1998-04-16 Bayer Ag Modifizierte Cytostatika
JP3101710B2 (ja) 1997-02-28 2000-10-23 工業技術院長 硫酸化オリゴ糖化合物
ID23424A (id) * 1997-05-14 2000-04-20 Bayer Ag Glikokonjugat dari 20(s)-kamptotesin
JP4669607B2 (ja) 1997-09-15 2011-04-13 ザ プロクター アンド ギャンブル カンパニー 抗微生物キノロン類、その組成物およびその使用
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US6613879B1 (en) * 1999-05-14 2003-09-02 Boehringer Ingelheim Pharma Kg FAP-activated anti-tumour compounds
DE10005275A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Neuartige Glycokonjugate
US7220824B1 (en) * 2000-08-28 2007-05-22 Bayer Aktiengesellschaft Integrin-mediated drug targeting
EP1219634A1 (en) * 2000-12-27 2002-07-03 Bayer Aktiengesellschaft Cytostatic-glycoconjugates having specifically cleavable peptidic linking units
EP1238678A1 (en) * 2001-03-08 2002-09-11 Bayer Aktiengesellschaft Enzyme-activated cytostatic conjugates with integrin ligands
WO2003040093A2 (de) * 2001-11-09 2003-05-15 Bayer Healthcare Ag Isotopencodierte affinitätsmarker 2
US7199149B2 (en) * 2003-10-01 2007-04-03 Bristol Myers Squibb Company Monocyclic and bicyclic lactams as factor Xa inhibitors
US20050227324A1 (en) 2003-12-19 2005-10-13 Genentech, Inc. Monovalent antibody fragments useful as therapeutics
HRP20110558T1 (hr) 2006-03-28 2011-09-30 Warner Chilcott Company Malatne soli i polimorfi od (3s, 5s)-7-[3-amino-5-metil-piperidinil]-1-ciklopropil-1, 4-dihidro-8-metoksi-4-okso-3-kinolinkarboksilne kiseline
WO2007110836A1 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A hydride reduction process for preparing quinolone intermediates
US7456279B2 (en) 2006-03-28 2008-11-25 The Procter & Gamble Company Coupling process for preparing quinolone intermediates
JP2018509384A (ja) * 2015-01-06 2018-04-05 イミューノヴァクシーン テクノロジーズ インコーポレイテッドＩｍｍｕｎｏｖａｃｃｉｎｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． リピドａ模倣体、調製方法、及びその使用
CN113599533A (zh) * 2015-11-25 2021-11-05 乐高化学生物科学股份有限公司 包含分支接头的抗体-药物缀合物及其相关方法
RS65660B1 (sr) 2015-11-25 2024-07-31 Ligachem Biosciences Inc Konјugati koji sadrže samozapaljive grupe i postupci povezani sa njima
KR101938800B1 (ko) 2017-03-29 2019-04-10 주식회사 레고켐 바이오사이언스 피롤로벤조디아제핀 이량체 전구체 및 이의 리간드-링커 접합체 화합물
JP7459063B2 (ja) 2018-05-09 2024-04-01 レゴケム バイオサイエンシズ， インク． 抗－ｃｄ１９抗体薬物複合体に関連する組成物および方法
KR20210028544A (ko) 2019-09-04 2021-03-12 주식회사 레고켐 바이오사이언스 인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도
KR102865327B1 (ko) * 2021-10-06 2025-09-29 주식회사 삼양사 포화 퓨로디옥신 유도체 화합물 및 그의 이차전지용 첨가제 용도

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Also Published As

Publication number Publication date
DK0819135T3 (da) 2000-05-08
RU2170234C2 (ru) 2001-07-10
DE59603678D1 (de) 1999-12-23
UA61054C2 (en) 2003-11-17
SK281785B6 (sk) 2001-07-10
DE19512484A1 (de) 1996-10-17
IS1822B (is) 2002-10-01
ES2140078T3 (es) 2000-02-16
PL322681A1 (en) 1998-02-16
CZ291098B6 (cs) 2002-12-11
BG63048B1 (bg) 2001-02-28
US6271342B1 (en) 2001-08-07
CA2217164A1 (en) 1996-10-10
MX9707613A (es) 1997-12-31
NZ305855A (en) 1999-11-29
WO1996031532A1 (de) 1996-10-10
NO974564D0 (no) 1997-10-02
BG101892A (en) 1998-05-29
AU5397696A (en) 1996-10-23
AU713466B2 (en) 1999-12-02
SK134597A3 (en) 1998-05-06
HUP9800513A3 (en) 1998-09-28
EE9700258A (et) 1998-04-15
HUP9800513A2 (hu) 1998-06-29
TW384290B (en) 2000-03-11
EE03619B1 (et) 2002-02-15
GR3032605T3 (en) 2000-05-31
EP0819135A1 (de) 1998-01-21
NO974564L (no) 1997-11-25
JPH11502860A (ja) 1999-03-09
ATE186738T1 (de) 1999-12-15
CZ314397A3 (cs) 1998-01-14
CN1185786A (zh) 1998-06-24
EP0819135B1 (de) 1999-11-17
BR9604825A (pt) 1999-01-05
KR19980703591A (ko) 1998-11-05
PL183574B1 (pl) 2002-06-28

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