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BR9812182A - Cloreto de n,n-bis(fenilcarbamoilmetil) dimetilamÈnio e seus derivados no tratamento da dor - Google Patents

Cloreto de n,n-bis(fenilcarbamoilmetil) dimetilamÈnio e seus derivados no tratamento da dor

Info

Publication number
BR9812182A
BR9812182A BR9812182-0A BR9812182A BR9812182A BR 9812182 A BR9812182 A BR 9812182A BR 9812182 A BR9812182 A BR 9812182A BR 9812182 A BR9812182 A BR 9812182A
Authority
BR
Brazil
Prior art keywords
phenylcarbamoylmethyl
pain
bis
derivatives
treatment
Prior art date
Application number
BR9812182-0A
Other languages
English (en)
Inventor
Bernard A Macleod
David M J Quastel
Original Assignee
Nortran Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nortran Pharmaceuticals Inc filed Critical Nortran Pharmaceuticals Inc
Publication of BR9812182A publication Critical patent/BR9812182A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"CLORETO DE N,N-BIS(FENILCARBAMOILMETIL)DIMETILAMÈNIO E SEUS DERIVADOS NO TRATAMENTO DA DOR". O cloreto de N,N-Bis(fenilcarbamoilmetil)dimetilamónio e seus derivados foram descobertos serem úteis no tratamento da dor ao mesmo tempo em que evitam os efeitos colaterais associados com as medicações convencionais.
BR9812182-0A 1997-09-03 1998-09-03 Cloreto de n,n-bis(fenilcarbamoilmetil) dimetilamÈnio e seus derivados no tratamento da dor BR9812182A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5631297P 1997-09-03 1997-09-03
PCT/CA1998/000842 WO1999011252A2 (en) 1997-09-03 1998-09-03 N,n-bis (phenylcarbamoylmethyl) dimethylammonium chloride and derivatives in the treatment of pain

Publications (1)

Publication Number Publication Date
BR9812182A true BR9812182A (pt) 2002-01-15

Family

ID=22003584

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812182-0A BR9812182A (pt) 1997-09-03 1998-09-03 Cloreto de n,n-bis(fenilcarbamoilmetil) dimetilamÈnio e seus derivados no tratamento da dor

Country Status (11)

Country Link
EP (1) EP1009397B1 (pt)
JP (1) JP2001514216A (pt)
CN (1) CN1276722A (pt)
AT (1) ATE238047T1 (pt)
AU (1) AU8970198A (pt)
BR (1) BR9812182A (pt)
CA (1) CA2303815A1 (pt)
DE (1) DE69813839T2 (pt)
ES (1) ES2197500T3 (pt)
TW (1) TW536401B (pt)
WO (1) WO1999011252A2 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2326777C (en) 1998-04-01 2011-12-20 Nortran Pharmaceuticals Inc. Aminocyclohexyl ether compounds and uses thereof
EP1087760A1 (en) * 1998-06-09 2001-04-04 Nortran Pharmaceuticals Inc. Compositions and methods for treatment of cough
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7057053B2 (en) 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
ATE325789T1 (de) 2003-05-02 2006-06-15 Cardiome Pharma Corp Aminocyclohexylether-verbindungen und deren verwendung
US7674820B2 (en) 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
US8058304B2 (en) 2004-04-01 2011-11-15 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
CA2561819A1 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
JP5583325B2 (ja) 2004-11-08 2014-09-03 カーディオム ファーマ コーポレイション イオンチャネル調節化合物の投与レジメ
AU2007322033B2 (en) 2006-11-20 2013-07-11 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
JP6205133B2 (ja) 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
AU2016301282B2 (en) 2015-08-03 2022-03-17 Children's Medical Center Corporation Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
KR102887727B1 (ko) 2019-03-11 2025-11-18 녹시온 테라퓨틱스 인코포레이티드 에스테르 치환된 이온 채널 차단제 및 사용 방법
MA55307A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques chargés et procédés d'utilisation
JP7692834B2 (ja) 2019-03-11 2025-06-16 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2020380118A1 (en) 2019-11-06 2022-05-19 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP4118070A4 (en) 2020-03-11 2024-04-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
WO2023100836A1 (ja) * 2021-11-30 2023-06-08 マルホ株式会社 医薬組成物
CN118265526A (zh) * 2021-11-30 2024-06-28 玛路弘株式会社 药物组合物

Also Published As

Publication number Publication date
EP1009397A2 (en) 2000-06-21
JP2001514216A (ja) 2001-09-11
ATE238047T1 (de) 2003-05-15
WO1999011252A2 (en) 1999-03-11
DE69813839T2 (de) 2004-03-04
EP1009397B1 (en) 2003-04-23
ES2197500T3 (es) 2004-01-01
DE69813839D1 (de) 2003-05-28
HK1028957A1 (en) 2001-03-16
AU8970198A (en) 1999-03-22
CN1276722A (zh) 2000-12-13
CA2303815A1 (en) 1999-03-11
WO1999011252A3 (en) 1999-05-06
TW536401B (en) 2003-06-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007.