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IS2469B - Fjölbrigða klópídógrel vetnissúlfat form - Google Patents

Fjölbrigða klópídógrel vetnissúlfat form

Info

Publication number
IS2469B
IS2469B IS5716A IS5716A IS2469B IS 2469 B IS2469 B IS 2469B IS 5716 A IS5716 A IS 5716A IS 5716 A IS5716 A IS 5716A IS 2469 B IS2469 B IS 2469B
Authority
IS
Iceland
Prior art keywords
hydrogen sulfate
clopidogrel hydrogen
sulfate forms
forms
clopidogrel
Prior art date
Application number
IS5716A
Other languages
English (en)
Other versions
IS5716A (is
Inventor
Bousquet André
Castro Bertrand
Saint-Germain Jean
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9527349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2469(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of IS5716A publication Critical patent/IS5716A/is
Publication of IS2469B publication Critical patent/IS2469B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS5716A 1998-06-15 2000-11-17 Fjölbrigða klópídógrel vetnissúlfat form IS2469B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807464A FR2779726B1 (fr) 1998-06-15 1998-06-15 Forme polymorphe de l'hydrogenosulfate de clopidogrel
PCT/FR1999/001371 WO1999065915A1 (fr) 1998-06-15 1999-06-10 Forme polymorphe de l'hydrogenosulfate de clopidogrel

Publications (2)

Publication Number Publication Date
IS5716A IS5716A (is) 2000-11-17
IS2469B true IS2469B (is) 2008-12-15

Family

ID=9527349

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5716A IS2469B (is) 1998-06-15 2000-11-17 Fjölbrigða klópídógrel vetnissúlfat form

Country Status (43)

Country Link
US (2) US6429210B1 (is)
EP (1) EP1087976B1 (is)
JP (1) JP3641584B2 (is)
KR (1) KR100511238B1 (is)
CN (1) CN1128805C (is)
AP (1) AP1344A (is)
AR (1) AR014854A1 (is)
AT (1) ATE222256T1 (is)
AU (1) AU752170B2 (is)
BG (1) BG64508B1 (is)
BR (1) BR9911219A (is)
CA (1) CA2334870C (is)
CO (1) CO5040084A1 (is)
CZ (1) CZ299654B6 (is)
DE (1) DE69902536T2 (is)
DK (1) DK1087976T3 (is)
DZ (1) DZ2817A1 (is)
EA (1) EA002386B1 (is)
EE (1) EE03972B1 (is)
EG (1) EG24015A (is)
ES (1) ES2181439T3 (is)
FR (1) FR2779726B1 (is)
HR (1) HRP20000863B1 (is)
HU (1) HU225871B1 (is)
ID (1) ID28264A (is)
IL (2) IL139790A0 (is)
IS (1) IS2469B (is)
ME (1) ME00686B (is)
MY (1) MY129439A (is)
NO (1) NO327161B1 (is)
NZ (1) NZ507914A (is)
OA (1) OA11567A (is)
PL (1) PL201894B1 (is)
PT (1) PT1087976E (is)
RS (1) RS49870B (is)
SA (1) SA99200321B1 (is)
SK (1) SK286340B6 (is)
TR (1) TR200003417T2 (is)
TW (1) TW562805B (is)
UA (1) UA70323C2 (is)
UY (1) UY25693A1 (is)
WO (1) WO1999065915A1 (is)
ZA (1) ZA200006386B (is)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
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US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
HUP0200438A3 (en) * 2002-02-06 2003-10-28 Egis Gyogyszergyar Nyilvanosan Novel clopidogrel hydrochloride polymorphs, process for the preparation thereof, their use and pharmaceutical compositions containing them
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CA2486174A1 (en) * 2002-05-31 2003-12-11 Schering Corporation Xanthine phosphodiesterase v inhibitor polymorphs
US6800759B2 (en) 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
CZ297472B6 (cs) * 2002-08-27 2006-12-13 Zentiva, A.S. Zpusob výroby clopidogrelu hydrogensulfátu krystalické formy I
US20040067995A1 (en) * 2002-10-02 2004-04-08 Wong Pancras C. Novel combination of a factor Xa inhibitor and clopidogrel
ITMI20022228A1 (it) * 2002-10-21 2004-04-22 Dinamite Dipharma S P A Sali di clopidogrel con acidi alchil-solforici.
WO2004048385A2 (en) * 2002-11-28 2004-06-10 Instytut Farmaceutyczny A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate
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US7732608B2 (en) * 2003-04-25 2010-06-08 Cadila Healthcare Limited Salts of clopidogrel and process for preparation
SK50112006A3 (sk) 2003-07-02 2006-05-04 Egis Gy�Gyszergy�R Rt. Spôsob prípravy amorfnej formy liečiva - inhibítora zrážania krvných doštičiek
US20070142637A1 (en) * 2003-07-02 2007-06-21 Egis Gyogyszergyar Rt. Process for the preparation of crystalline polymorph of a platelet aggregation inhibitor drug
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DE10337773A1 (de) * 2003-08-13 2005-03-24 Krka Tovarna Zdravil, D.D. Kristallisation von festen Formen von Clopidogrel-Additionssalzen
GB0321256D0 (en) * 2003-09-11 2003-10-08 Generics Uk Ltd Novel crystalline compounds
ES2339944T3 (es) * 2003-11-03 2010-05-27 Cadila Healthcare Limited Procedimientos para preparar la forma i de bisulfato de (s)-(+)-clopidogrel.
CA2457459A1 (en) * 2004-02-11 2005-08-11 Brantford Chemicals Inc. Resolution of racemates of methyl alpha-5-(4,5,6,7-tetrahydro(3,2-c)thienopyridyl)-(2-chlorophenyl) acetate
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EP1772455A3 (en) * 2004-03-05 2007-06-27 IPCA Laboratories Limited Industrial process for preparation a polmorph of clopidogrel hydrogen sulphate
CA2562532C (en) * 2004-04-09 2010-02-16 Hanmi Pharm. Co., Ltd. Crystalline clopidogrel naphthalenesulfonate or hydrate thereof, method for preparing same and pharmaceutical composition containing same
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AU2005236034A1 (en) * 2004-04-20 2005-11-03 Sanofi-Aventis Polymorphic forms of methyl (+) - (S) -alpha- (2-chlorophenyl) -6, 7-dihydrothieno [3,2-c]pyridine-5(4H) acetate hydrobromide, clopidrogel hydrobromide
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CN102367257B (zh) * 2011-11-21 2014-05-07 天津红日药业股份有限公司 氯吡格雷盐酸盐的单晶晶型，它们的制备及应用
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JP5905165B2 (ja) 2013-08-02 2016-04-20 サノフイ アセチルサリチル酸およびクロピドグレルを含む医薬錠剤
CN103524528A (zh) * 2013-09-16 2014-01-22 吉林省博大伟业制药有限公司 一种改进的ⅱ型硫酸氢氯吡格雷结晶制备方法
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KR101710922B1 (ko) 2015-06-03 2017-02-28 경동제약 주식회사 클로피도그렐 황산염 결정형 i형의 제조방법
CN107698620A (zh) 2015-06-23 2018-02-16 江苏天士力帝益药业有限公司 一种氘代噻吩并哌啶衍生物、制备方法及其应用
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CN107163060B (zh) * 2017-05-24 2021-03-02 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型ii制备方法
CN107337683B (zh) * 2017-08-16 2019-08-16 中荣凯特（北京）生物科技有限公司 一种噻吩并吡啶类衍生物硫酸氢盐的晶型ⅱ及其制备方法和应用
CN109438467B (zh) * 2018-11-14 2021-03-26 四川青木制药有限公司 一种硫酸氢氯吡格雷ⅱ型球形结晶的制备方法
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Family Cites Families (2)

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FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2664276B1 (fr) 1990-07-04 1992-10-23 Sanofi Sa Derive thienyl-2 glycidique, son procede de preparation et son utilisation comme intermediaire de synthese.

Also Published As

Publication number Publication date
AR014854A1 (es) 2001-04-11
KR100511238B1 (ko) 2005-08-31
TR200003417T2 (tr) 2001-03-21
IL139790A (en) 2006-10-05
EP1087976A1 (fr) 2001-04-04
NO327161B1 (no) 2009-05-04
BR9911219A (pt) 2001-03-06
US6504030B1 (en) 2003-01-07
US6429210B1 (en) 2002-08-06
EP1087976B1 (fr) 2002-08-14
FR2779726A1 (fr) 1999-12-17
PL344998A1 (en) 2001-11-19
NO20006395L (no) 2001-02-15
HUP0104343A3 (en) 2003-03-28
UA70323C2 (uk) 2004-10-15
SA99200321B1 (ar) 2006-10-11
HU225871B1 (en) 2007-11-28
EE03972B1 (et) 2003-02-17
CZ20004637A3 (cs) 2001-04-11
PT1087976E (pt) 2002-11-29
BG104987A (en) 2001-11-30
YU77700A (sh) 2003-04-30
KR20010052835A (ko) 2001-06-25
RS49870B (sr) 2008-08-07
SK286340B6 (en) 2008-07-07
EA002386B1 (ru) 2002-04-25
JP3641584B2 (ja) 2005-04-20
HK1033829A1 (en) 2001-09-28
DK1087976T3 (da) 2002-12-02
HRP20000863B1 (en) 2003-04-30
AU752170B2 (en) 2002-09-05
ZA200006386B (en) 2001-05-07
AU4048399A (en) 2000-01-05
TW562805B (en) 2003-11-21
IL139790A0 (en) 2002-02-10
ATE222256T1 (de) 2002-08-15
MY129439A (en) 2007-04-30
CA2334870C (en) 2005-03-15
CO5040084A1 (es) 2001-05-29
US20020198229A1 (en) 2002-12-26
EG24015A (en) 2008-03-24
AP1344A (en) 2004-12-15
NO20006395D0 (no) 2000-12-14
OA11567A (en) 2004-05-24
CN1305483A (zh) 2001-07-25
PL201894B1 (pl) 2009-05-29
CA2334870A1 (en) 1999-12-23
UY25693A1 (es) 2000-03-31
IS5716A (is) 2000-11-17
FR2779726B1 (fr) 2001-05-18
WO1999065915A1 (fr) 1999-12-23
EE200000745A (et) 2002-04-15
ES2181439T3 (es) 2003-02-16
CZ299654B6 (cs) 2008-10-08
SK19092000A3 (sk) 2001-05-10
ID28264A (id) 2001-05-10
NZ507914A (en) 2002-11-26
HRP20000863A2 (en) 2001-10-31
CN1128805C (zh) 2003-11-26
BG64508B1 (bg) 2005-05-31
DE69902536T2 (de) 2003-03-13
DE69902536D1 (en) 2002-09-19
EA200001187A1 (ru) 2001-08-27
ME00686B (me) 2008-08-07
AP2000001979A0 (en) 2000-12-31
DZ2817A1 (fr) 2004-06-02
HUP0104343A2 (hu) 2002-03-28
JP2002518399A (ja) 2002-06-25

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