IS2325B - Örgerðar samsetningar epleróns - Google Patents
Örgerðar samsetningar eplerónsInfo
- Publication number
- IS2325B IS2325B IS5953A IS5953A IS2325B IS 2325 B IS2325 B IS 2325B IS 5953 A IS5953 A IS 5953A IS 5953 A IS5953 A IS 5953A IS 2325 B IS2325 B IS 2325B
- Authority
- IS
- Iceland
- Prior art keywords
- microplated
- eplerone
- formulations
- microplated formulations
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11164698P | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/029136 WO2000033847A1 (en) | 1998-12-09 | 1999-12-08 | Micronized eplerenone compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS5953A IS5953A (is) | 2001-05-25 |
| IS2325B true IS2325B (is) | 2007-12-15 |
Family
ID=22339668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS5953A IS2325B (is) | 1998-12-09 | 2001-05-25 | Örgerðar samsetningar epleróns |
Country Status (30)
| Country | Link |
|---|---|
| US (7) | US6410054B1 (is) |
| EP (1) | EP1135139B1 (is) |
| JP (1) | JP2002531508A (is) |
| KR (1) | KR100671275B1 (is) |
| CN (1) | CN1230179C (is) |
| AR (1) | AR028982A1 (is) |
| AT (1) | ATE249223T1 (is) |
| AU (1) | AU763166B2 (is) |
| BR (1) | BR9915964A (is) |
| CA (1) | CA2326842A1 (is) |
| CZ (1) | CZ20011942A3 (is) |
| DE (1) | DE69911240T2 (is) |
| DK (1) | DK1135139T3 (is) |
| EA (1) | EA003266B1 (is) |
| ES (1) | ES2207977T3 (is) |
| HK (1) | HK1041641B (is) |
| HU (1) | HU224428B1 (is) |
| ID (1) | ID30115A (is) |
| IL (1) | IL143301A0 (is) |
| IS (1) | IS2325B (is) |
| MY (1) | MY125651A (is) |
| NO (1) | NO20012782L (is) |
| NZ (1) | NZ511869A (is) |
| PL (1) | PL198425B1 (is) |
| PT (1) | PT1135139E (is) |
| TR (1) | TR200101643T2 (is) |
| TW (1) | TWI234459B (is) |
| UA (1) | UA74141C2 (is) |
| WO (1) | WO2000033847A1 (is) |
| ZA (1) | ZA200104361B (is) |
Families Citing this family (94)
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|---|---|---|---|---|
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| EP1527782A1 (en) * | 1999-12-08 | 2005-05-04 | Pharmacia Corporation | Nanoparticulate eplerenone compositions |
| PT1175220E (pt) * | 1999-12-08 | 2005-07-29 | Pharmacia Corp | Composicoes de eplerenona em nanoparticulas |
| EP1280533A2 (en) * | 2000-05-11 | 2003-02-05 | Pharmacia Corporation | Aldosterone antagonist composition for release during aldosterone acrophase |
| EP1368009A2 (en) * | 2000-07-27 | 2003-12-10 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
| US20020123485A1 (en) * | 2000-07-27 | 2002-09-05 | Alexander John C. | Epoxy steroidal aldosterone antagonist and beta-adrenergic antagonist combination therapy for treatment of congestive heart failure |
| EP1313485B1 (en) * | 2000-08-28 | 2005-10-12 | Pharmacia Corporation | Use of an aldosterone receptor antagonist to improve cognitive function |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| JP4021327B2 (ja) | 2001-03-12 | 2007-12-12 | インターセプト ファーマスーティカル インコーポレイテッド | Fxrに対する作用薬としてのステロイド |
| US20040173146A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US20040173147A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| GB0114532D0 (en) * | 2001-06-14 | 2001-08-08 | Jagotec Ag | Novel compositions |
| ATE363917T1 (de) * | 2001-07-19 | 2007-06-15 | Pharmacia Corp | Kombination von einem aldosterone rezeptor antagonisten und einem hmg coa reduktase hemmer |
| MXPA04005803A (es) * | 2001-12-13 | 2004-11-01 | Pharmacia Corp | Metodos para tratamiento o profilaxis de efectos patogenicos mediados por aldosterona en un sujeto utilizando un antagonista de aldosterona epoxi-esteroidal. |
| CA2473797A1 (en) * | 2002-01-30 | 2003-08-07 | Pharmacia Corporation | Aldosterone antagonist and non-steroidal anti-inflammatory agent combination therapy to prevent or treat cardiovascular disorders |
| PL208114B1 (pl) * | 2002-02-26 | 2011-03-31 | Astrazeneca Ab | Kompozycja farmaceutyczna, sposób jej wytwarzania i zastosowanie |
| BR0308475A (pt) * | 2002-03-20 | 2005-01-11 | Pharmacia Corp | Formulação de eplerenona estável na armazenagem |
| US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
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-
1999
- 1999-08-12 UA UA2001063853A patent/UA74141C2/uk unknown
- 1999-12-07 AR ARP990106255A patent/AR028982A1/es not_active Application Discontinuation
- 1999-12-08 AT AT99963052T patent/ATE249223T1/de active
- 1999-12-08 PL PL349632A patent/PL198425B1/pl not_active IP Right Cessation
- 1999-12-08 HK HK02103113.4A patent/HK1041641B/zh unknown
- 1999-12-08 DE DE69911240T patent/DE69911240T2/de not_active Expired - Lifetime
- 1999-12-08 CA CA002326842A patent/CA2326842A1/en not_active Abandoned
- 1999-12-08 MY MYPI99005328A patent/MY125651A/en unknown
- 1999-12-08 CN CNB998141100A patent/CN1230179C/zh not_active Expired - Fee Related
- 1999-12-08 NZ NZ511869A patent/NZ511869A/en unknown
- 1999-12-08 IL IL14330199A patent/IL143301A0/xx not_active IP Right Cessation
- 1999-12-08 ID IDW00200101191A patent/ID30115A/id unknown
- 1999-12-08 PT PT99963052T patent/PT1135139E/pt unknown
- 1999-12-08 JP JP2000586339A patent/JP2002531508A/ja active Pending
- 1999-12-08 BR BR9915964-3A patent/BR9915964A/pt not_active Application Discontinuation
- 1999-12-08 TR TR2001/01643T patent/TR200101643T2/xx unknown
- 1999-12-08 US US09/456,614 patent/US6410054B1/en not_active Expired - Lifetime
- 1999-12-08 EP EP99963052A patent/EP1135139B1/en not_active Expired - Lifetime
- 1999-12-08 EA EA200100519A patent/EA003266B1/ru not_active IP Right Cessation
- 1999-12-08 ES ES99963052T patent/ES2207977T3/es not_active Expired - Lifetime
- 1999-12-08 DK DK99963052T patent/DK1135139T3/da active
- 1999-12-08 AU AU19368/00A patent/AU763166B2/en not_active Expired
- 1999-12-08 HU HU0104718A patent/HU224428B1/hu not_active IP Right Cessation
- 1999-12-08 CZ CZ20011942A patent/CZ20011942A3/cs unknown
- 1999-12-08 KR KR1020017007041A patent/KR100671275B1/ko not_active Expired - Fee Related
- 1999-12-08 WO PCT/US1999/029136 patent/WO2000033847A1/en not_active Ceased
-
2000
- 2000-02-22 TW TW088121495A patent/TWI234459B/zh not_active IP Right Cessation
-
2001
- 2001-05-25 IS IS5953A patent/IS2325B/is unknown
- 2001-05-28 ZA ZA200104361A patent/ZA200104361B/en unknown
- 2001-06-06 NO NO20012782A patent/NO20012782L/no unknown
-
2002
- 2002-01-31 US US10/066,360 patent/US6592902B2/en not_active Expired - Lifetime
- 2002-03-19 US US10/101,361 patent/US6495165B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,712 patent/US6558707B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,930 patent/US6534093B1/en not_active Expired - Lifetime
- 2002-11-06 US US10/289,025 patent/US6863902B2/en not_active Expired - Fee Related
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2004
- 2004-04-02 US US10/817,577 patent/US7157101B2/en not_active Expired - Lifetime
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