IS2310B - Nefholssamsetning úr rótigótíni - Google Patents

Nefholssamsetning úr rótigótíni

Info

Publication number: IS2310B
Authority: IS; Iceland
Prior art keywords: rotigotine; nasal composition; cyclodextrin; alpha; viscosity
Prior art date: 2003-12-23

Application number

IS8487A

Other languages

English (en)

Other versions

IS8487A (is

Inventor

Krämer Robert

Original Assignee

Schwarz Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-23

Filing date

2006-05-26

Publication date

2007-11-15

2006-05-26 Application filed by Schwarz Pharma Ag filed Critical Schwarz Pharma Ag

2006-05-26 Publication of IS8487A publication Critical patent/IS8487A/is

2007-11-15 Publication of IS2310B publication Critical patent/IS2310B/is

Links

KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical group CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 2
229960003179 rotigotine Drugs 0.000 title abstract 2
229920001450 Alpha-Cyclodextrin Polymers 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 abstract 1
229940043377 alpha-cyclodextrin Drugs 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IS8487A 2003-12-23 2006-05-26 Nefholssamsetning úr rótigótíni IS2310B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03029680A EP1547592A1 (en)	2003-12-23	2003-12-23	Intranasal formulation of rotigotine
PCT/EP2004/014626 WO2005063236A1 (en)	2003-12-23	2004-12-22	Intranasal formulation of rotigotine

Publications (2)

Publication Number	Publication Date
IS8487A IS8487A (is)	2006-05-26
IS2310B true IS2310B (is)	2007-11-15

Family

ID=34530709

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8487A IS2310B (is)	2003-12-23	2006-05-26	Nefholssamsetning úr rótigótíni

Country Status (27)

Country	Link
US (1)	US7683040B2 (is)
EP (2)	EP1547592A1 (is)
JP (1)	JP4430067B2 (is)
KR (1)	KR100718760B1 (is)
CN (1)	CN100374112C (is)
AT (1)	ATE326961T1 (is)
AU (1)	AU2004308641B2 (is)
BR (1)	BRPI0407845A (is)
CA (1)	CA2516400C (is)
CY (1)	CY1105131T1 (is)
DE (1)	DE602004000982T2 (is)
DK (1)	DK1605932T3 (is)
EA (1)	EA008005B1 (is)
ES (1)	ES2262122T3 (is)
HR (1)	HRP20060240T3 (is)
IL (1)	IL170297A (is)
IS (1)	IS2310B (is)
MX (1)	MXPA05008909A (is)
NO (1)	NO20054018L (is)
NZ (1)	NZ541875A (is)
PL (1)	PL1605932T3 (is)
PT (1)	PT1605932E (is)
RS (1)	RS50534B (is)
SI (1)	SI1605932T1 (is)
UA (1)	UA79196C2 (is)
WO (1)	WO2005063236A1 (is)
ZA (1)	ZA200506550B (is)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19814084B4 (de)	1998-03-30	2005-12-22	Lts Lohmann Therapie-Systeme Ag	D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE10041478A1 (de)	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
DE10041479A1 (de) *	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
US20040048779A1 (en) *	2002-05-06	2004-03-11	Erwin Schollmayer	Use of rotigotine for treating the restless leg syndrome
DE10234673B4 (de) *	2002-07-30	2007-08-16	Schwarz Pharma Ag	Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8246979B2 (en)	2002-07-30	2012-08-21	Ucb Pharma Gmbh	Transdermal delivery system for the administration of rotigotine
US8211462B2 (en) *	2002-07-30	2012-07-03	Ucb Pharma Gmbh	Hot-melt TTS for administering rotigotine
US8246980B2 (en)	2002-07-30	2012-08-21	Ucb Pharma Gmbh	Transdermal delivery system
SI1426049T1 (en)	2002-12-02	2005-08-31	Sanol Arznei Schwarz Gmbh	Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease
DE10261696A1 (de)	2002-12-30	2004-07-15	Schwarz Pharma Ag	Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
DE10334188B4 (de) *	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
DE10359528A1 (de) *	2003-12-18	2005-07-28	Schwarz Pharma Ag	(S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
EP1547592A1 (en)	2003-12-23	2005-06-29	Schwarz Pharma Ag	Intranasal formulation of rotigotine
DE10361258A1 (de) *	2003-12-24	2005-07-28	Schwarz Pharma Ag	Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) *	2004-02-20	2005-09-08	Schwarz Pharma Ag	Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) *	2004-03-24	2006-07-06	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
TWI392670B (zh) *	2006-06-22	2013-04-11	Ucb Pharma Gmbh	經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途
EP1987815A1 (en) *	2007-05-04	2008-11-05	Schwarz Pharma Ag	Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders
AU2008328920B2 (en)	2007-11-28	2013-09-12	Ucb Pharma Gmbh	Polymorphic form of Rotigotine
US8580801B2 (en)	2008-07-23	2013-11-12	Robert I. Henkin	Phosphodiesterase inhibitor treatment
EP2281559A1 (en)	2009-06-26	2011-02-09	UCB Pharma GmbH	Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
PT3257504T (pt)	2009-12-22	2024-09-03	Ucb Biopharma Sprl	Polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina
EP2559435A1 (en)	2011-08-19	2013-02-20	UCB Pharma GmbH	Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke
DE102012013439A1 (de)	2012-07-03	2014-01-23	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor
WO2013075823A1 (en)	2011-11-22	2013-05-30	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermal therapeutic system comprising rotigotine and crystallization inhibitor
DE102012013421A1 (de)	2012-07-03	2014-01-09	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermales therapeutisches System (TTS) mit Rotigotin
CN103768043B (zh) *	2012-10-22	2015-12-09	苏州药明康德新药开发股份有限公司	采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法
TW201431570A (zh)	2012-11-22	2014-08-16	Ucb Pharma Gmbh	用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
CA2916183C (en)	2013-07-03	2022-03-29	Lts Lohmann Therapie-Systeme Ag	Transdermal therapeutic system with electronic component
WO2015126944A1 (en)	2014-02-18	2015-08-27	Henkin Robert I	Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
ES2924899T3 (es)	2014-05-20	2022-10-11	Lts Lohmann Therapie Systeme Ag	Sistema de administración transdérmica que contiene rotigotina
CN106456567A (zh)	2014-05-20	2017-02-22	Lts勒曼治疗系统股份公司	在经皮递送系统中调节活性剂释放的方法
JP6599899B2 (ja)	2014-05-20	2019-10-30	エルテーエスローマンテラピー−ジステーメアーゲー	界面介在物を含む経皮送達システム
US9956201B2 (en)	2014-07-21	2018-05-01	Spriaso Llc	Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms
CN110917125B (zh) *	2020-01-02	2022-08-12	安徽中医药大学	一种罗替戈汀鼻用胶束温敏凝胶的制备方法
JP2025502075A (ja) *	2022-01-06	2025-01-24	シラノセラピューティクス，インコーポレイテッド	パーキンソン病治療剤の改善された鼻投与
CN120053353A (zh) *	2024-05-31	2025-05-30	纳索菲德(上海)制药技术有限公司	一种巴氯芬鼻脑递释组合物

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5108991A (en)	1975-06-19	1992-04-28	Whitby Research, Inc.	Vehicle composition containing 1-substituted azacycloalkan-2-ones
DE3783683T2 (de)	1986-01-31	1993-05-19	Whitby Research Inc	Hautpenetration verbessernde zusammensetzungen.
US5218113A (en)	1986-01-31	1993-06-08	Whitby Research, Inc.	N-substituted thiolactams
US4992422A (en)	1986-01-31	1991-02-12	Whitby Research, Inc.	Compositions comprising 1-substituted azacycloalkanes
US4755535A (en)	1986-04-23	1988-07-05	Nelson Research & Development Co.	Compositions comprising 1-substituted azacycloalkenes
US5073544A (en)	1986-08-15	1991-12-17	Whitby, Inc.	Transdermal compositions of 1-oxohydrocarbyl-substituted azacyclohexanes
US4902676A (en)	1986-09-29	1990-02-20	Nelson Research & Development Co.	Compositions comprising N,N-dialkylalkanamides
DE3868866D1 (de)	1987-11-20	1992-04-09	Erba Carlo Spa	Ergolinderivate mit antiparkinsonwirkung.
US5472946A (en)	1988-04-08	1995-12-05	Peck; James V.	Transdermal penetration enhancers
US5073844A (en) *	1991-01-11	1991-12-17	The Annlouise Partnership	Lighted baggage piece
US6086905A (en)	1991-03-21	2000-07-11	Peck; James V.	Topical compositions useful as skin penetration barriers
US5308625A (en)	1992-09-02	1994-05-03	Cygnus Therapeutic Systems	Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
US5989586A (en)	1992-10-05	1999-11-23	Cygnus, Inc.	Two-phase matrix for sustained release drug delivery device
DK0865789T3 (da)	1993-03-26	2005-07-18	Franciscus Wilhelmus He Merkus	Farmaceutiske præparater til intranasal administration af dihydroergotamin
GB9324018D0 (en)	1993-11-23	1994-01-12	Merck Sharp & Dohme	Therapeutic agents
US5771890A (en)	1994-06-24	1998-06-30	Cygnus, Inc.	Device and method for sampling of substances using alternating polarity
AU2944995A (en)	1994-06-24	1996-01-19	Cygnus, Inc.	Iontophoretic sampling device and method
AUPN814496A0 (en)	1996-02-19	1996-03-14	Monash University	Dermal penetration enhancer
DE19814084B4 (de)	1998-03-30	2005-12-22	Lts Lohmann Therapie-Systeme Ag	D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE10041479A1 (de) *	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
AUPQ969800A0 (en)	2000-08-28	2000-09-21	Fujisawa Pharmaceutical Co., Ltd.	Pyrazolopyridine compound and pharmaceutical use thereof
PT1256339E (pt)	2001-05-08	2004-02-27	Lohmann Therapie Syst Lts	Sistema terapeutico transdermico para doenca de parkinson que induz niveis plasmaticos altos de rotigotina
FR2829028B1 (fr)	2001-08-29	2004-12-17	Aventis Pharma Sa	Association d'un antagoniste du recepteur cb1 et d'un produit qui active la neurotransmission dopaminergique dans le cerveau, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de
HU227543B1 (en)	2001-09-28	2011-08-29	Richter Gedeon Nyrt	N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them
FR2834212B1 (fr)	2001-12-27	2004-07-09	Besins Int Belgique	Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
CA2481934A1 (en)	2002-04-18	2003-10-30	Pharmacia Corporation	Combinations of cox-2 inhibitors and other agents for the treatment of parkinson's disease
US7038085B2 (en)	2002-10-25	2006-05-02	Collegium Pharmaceutical, Inc.	Stereoisomers of p-hydroxy-milnacipran, and methods of use thereof
US9102726B2 (en)	2002-12-04	2015-08-11	Argos Therapeutics, Inc.	Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same
DE10334188B4 (de)	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
US20050032873A1 (en)	2003-07-30	2005-02-10	Wyeth	3-Amino chroman and 2-amino tetralin derivatives
DE10359528A1 (de)	2003-12-18	2005-07-28	Schwarz Pharma Ag	(S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
EP1547592A1 (en)	2003-12-23	2005-06-29	Schwarz Pharma Ag	Intranasal formulation of rotigotine
JP2007518754A (ja)	2004-01-22	2007-07-12	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	モノアミン神経伝達物質再取込みインヒビターとドーパミンアゴニストを含む医薬組成物
KR20070045254A (ko)	2004-08-02	2007-05-02	슈바르츠 파르마 악티엔게젤샤프트	인돌리진 카르복사미드 및 그 아자 및 디아자유도체
DE102004054634A1 (de)	2004-11-12	2006-05-18	Schwarz Pharma Ag	Azaindolcarboxamide

2003
- 2003-12-23 EP EP03029680A patent/EP1547592A1/en not_active Withdrawn
2004
- 2004-12-22 KR KR1020057017173A patent/KR100718760B1/ko not_active Expired - Fee Related
- 2004-12-22 CN CNB2004800109827A patent/CN100374112C/zh not_active Expired - Fee Related
- 2004-12-22 JP JP2006508291A patent/JP4430067B2/ja not_active Expired - Fee Related
- 2004-12-22 EP EP04804221A patent/EP1605932B1/en not_active Expired - Lifetime
- 2004-12-22 NZ NZ541875A patent/NZ541875A/en unknown
- 2004-12-22 AU AU2004308641A patent/AU2004308641B2/en not_active Ceased
- 2004-12-22 PL PL04804221T patent/PL1605932T3/pl unknown
- 2004-12-22 WO PCT/EP2004/014626 patent/WO2005063236A1/en not_active Ceased
- 2004-12-22 RS YUP-2006/0653A patent/RS50534B/sr unknown
- 2004-12-22 UA UAA200508587A patent/UA79196C2/uk unknown
- 2004-12-22 EA EA200501159A patent/EA008005B1/ru not_active IP Right Cessation
- 2004-12-22 MX MXPA05008909A patent/MXPA05008909A/es active IP Right Grant
- 2004-12-22 DE DE602004000982T patent/DE602004000982T2/de not_active Expired - Lifetime
- 2004-12-22 HR HR20060240T patent/HRP20060240T3/xx unknown
- 2004-12-22 CA CA002516400A patent/CA2516400C/en not_active Expired - Fee Related
- 2004-12-22 BR BRPI0407845-4A patent/BRPI0407845A/pt not_active IP Right Cessation
- 2004-12-22 DK DK04804221T patent/DK1605932T3/da active
- 2004-12-22 ES ES04804221T patent/ES2262122T3/es not_active Expired - Lifetime
- 2004-12-22 SI SI200430027T patent/SI1605932T1/sl unknown
- 2004-12-22 PT PT04804221T patent/PT1605932E/pt unknown
- 2004-12-22 AT AT04804221T patent/ATE326961T1/de active
- 2004-12-22 US US10/545,530 patent/US7683040B2/en not_active Expired - Fee Related
2005
- 2005-08-16 ZA ZA200506550A patent/ZA200506550B/en unknown
- 2005-08-16 IL IL170297A patent/IL170297A/en not_active IP Right Cessation
- 2005-08-30 NO NO20054018A patent/NO20054018L/no not_active Application Discontinuation
2006
- 2006-05-26 IS IS8487A patent/IS2310B/is unknown
- 2006-08-09 CY CY20061101113T patent/CY1105131T1/el unknown

Also Published As

Publication number	Publication date
DE602004000982T2 (de)	2007-05-10
US7683040B2 (en)	2010-03-23
ZA200506550B (en)	2006-05-31
AU2004308641B2 (en)	2006-10-26
MXPA05008909A (es)	2005-10-05
EA008005B1 (ru)	2007-02-27
EP1605932B1 (en)	2006-05-24
PL1605932T3 (pl)	2006-09-29
KR100718760B1 (ko)	2007-05-15
UA79196C2 (en)	2007-05-25
JP4430067B2 (ja)	2010-03-10
IL170297A (en)	2010-06-30
NZ541875A (en)	2008-08-29
DE602004000982D1 (de)	2006-06-29
RS50534B (sr)	2010-05-07
JP2006526004A (ja)	2006-11-16
HRP20060240T3 (hr)	2007-05-31
SI1605932T1 (sl)	2006-08-31
CN1777422A (zh)	2006-05-24
IS8487A (is)	2006-05-26
ES2262122T3 (es)	2006-11-16
NO20054018L (no)	2005-08-30
ATE326961T1 (de)	2006-06-15
EP1547592A1 (en)	2005-06-29
CA2516400A1 (en)	2005-07-14
DK1605932T3 (da)	2006-09-18
CA2516400C (en)	2009-10-27
WO2005063236A1 (en)	2005-07-14
BRPI0407845A (pt)	2006-02-14
CY1105131T1 (el)	2009-11-04
HK1083596A1 (en)	2006-07-07
US20070191308A1 (en)	2007-08-16
AU2004308641A1 (en)	2005-07-14
CN100374112C (zh)	2008-03-12
EP1605932A1 (en)	2005-12-21
PT1605932E (pt)	2006-08-31
KR20060040578A (ko)	2006-05-10
EA200501159A1 (ru)	2006-02-24

Publication	Publication Date	Title
IS2310B (is)	2007-11-15	Nefholssamsetning úr rótigótíni
NO20061840L (no)	2006-06-26	Legemiddelbelegg som tilveiebringer hoy legemiddeltilsetning og fremgangsmater for a tilveiebringe samme
BR0011433A (pt)	2002-03-05	Imidazoquinolinas substituìdas com sulfonamida e sulfamida
EP1539122A4 (en)	2010-03-10	PHARMACEUTICAL AQUEOUS 2,6-DIISOPROPYLPHENOL COMPOSITIONS
CY1112981T1 (el)	2016-04-13	Μεθοδος και συνθεση για την αγωγη της ρινιτιδας
BRPI0412895A (pt)	2006-10-03	combinações de substáncias ativas fungicidas
MA28722B1 (fr)	2007-07-02	Composition pharmaceutique orodispersible pour administration oromucosale ou sublinguale d'agomelatine.
ATE367165T1 (de)	2007-08-15	Xanthangummi enthaltende reepithelialisierende pharmazeutische zubereitungen
DZ3269A1 (fr)	2001-08-09	Composition pharmaceutique comprenant le pemetrexed avec le monothioglycerol, la cysteine l ou l'acide thioglycolique
ATE464878T1 (de)	2010-05-15	Pharmazeutische zusammensetzung zur nasalen anwendung von fentanyl
ATE357212T1 (de)	2007-04-15	Wässrige pharmazeutische lösung enthaltend oxymetazolin und/oder xylometazolin
DE60239165D1 (de)	2011-03-24	Perkutane absorptionszubereitungen mit 3-methyl-1-phenyl-2-pyrazolin-5-on
ATE352287T1 (de)	2007-02-15	Flüssige pharmazeutische zusammensetzungen auf wasserbasis in suspensionsform zur oralen verabreichung von ibuprofen
WO2010066437A3 (de)	2011-02-24	Wässrige zusammensetzung enthaltend dexpanthenol und natriumchlorid
ATE410164T1 (de)	2008-10-15	Wässrige flüssige preparation von pranoprofen
UY27376A1 (es)	2003-02-28	Formulación de medicamento que contiene un antagonista de ltb4
HRP20070081T3 (hr)	2007-04-30	Nazalni farmaceutski pripravak piribedila
EP1556022A4 (en)	2010-03-10	Aqueous 2,6-diisopropylprophenol-containing pharmaceutical compositions
FR2834894B1 (fr)	2004-02-27	Composition pharmaceutique orodispersible de piribedil
FR2856302B1 (fr)	2005-12-02	Composition pharmaceutique utilisee en tant qu'agent anti-infectueux des voies respiratoires superieures
FR2826367B1 (fr)	2004-01-30	Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycopyranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant
ATE424399T1 (de)	2009-03-15	Pharmazeutische zusammensetzungen von risperidon in wässriger lösung
CO5560535A2 (es)	2005-09-30	Formulacion de medicamento que contiene un agonista ltb4
ITMC20030023A1 (it)	2004-09-07	"soluzione oftalmica acquosa preposta
ITRM20030213A1 (it)	2004-11-03	Composizione farmaceutica per l'uso nella cura delle