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IL89156A - Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics - Google Patents

Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics

Info

Publication number
IL89156A
IL89156A IL89156A IL8915689A IL89156A IL 89156 A IL89156 A IL 89156A IL 89156 A IL89156 A IL 89156A IL 8915689 A IL8915689 A IL 8915689A IL 89156 A IL89156 A IL 89156A
Authority
IL
Israel
Prior art keywords
methyl
group
tetrahydroisoquinoline
piperidinyl
therapeutics
Prior art date
Application number
IL89156A
Other languages
English (en)
Other versions
IL89156A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8809447A external-priority patent/FR2634204B2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL89156A0 publication Critical patent/IL89156A0/xx
Publication of IL89156A publication Critical patent/IL89156A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL89156A 1988-07-12 1989-02-02 Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics IL89156A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8809447A FR2634204B2 (fr) 1987-08-07 1988-07-12 Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL89156A0 IL89156A0 (en) 1989-09-10
IL89156A true IL89156A (en) 1993-05-13

Family

ID=9368349

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89156A IL89156A (en) 1988-07-12 1989-02-02 Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics

Country Status (15)

Country Link
US (1) US4925850A (da)
EP (1) EP0351255B1 (da)
JP (1) JPH0225481A (da)
KR (1) KR900001676A (da)
AT (1) ATE95816T1 (da)
AU (1) AU606778B2 (da)
DE (1) DE68909855D1 (da)
DK (1) DK50089A (da)
FI (1) FI890520L (da)
HU (1) HU201543B (da)
IL (1) IL89156A (da)
NO (1) NO171786C (da)
NZ (1) NZ227853A (da)
PT (1) PT89643B (da)
ZA (1) ZA89905B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.
US5132311A (en) * 1990-06-27 1992-07-21 G. D. Searle & Co. Cyanoquanidine type III antiarrhythmic agents and use
FR2747386B1 (fr) * 1996-04-12 1998-05-15 Synthelabo Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
JP2000517301A (ja) * 1996-08-14 2000-12-26 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー テトラヒドロイソキノリン誘導体およびそれらの薬理学的使用
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
ID28385A (id) 1998-10-08 2001-05-17 Smithkline Beecham Plc Turunan-turunan tetrahidrobenzazepina yang berguna sebagai modulator reseptor d3 dopamina (bahan antipsikotik)
DE10060176B4 (de) 2000-12-04 2008-06-19 Precitec Kg Laserbearbeitungskopf
KR101042208B1 (ko) * 2008-09-26 2011-06-20 현대종합금속 주식회사 셀프 쉴디드(ｓｅｌｆ－ｓｈｉｅｌｄｅｄ) 아크 용접 플럭스 충전 와이어
AU2010264422B2 (en) 2009-06-26 2014-12-18 Sanofi Novel fumarate salts of a histamine H3 receptor antagonist

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1580180A (da) * 1967-03-14 1969-09-05
FR7607M (da) * 1968-04-25 1970-01-19
GB1250719A (da) * 1969-03-19 1971-10-20
US3836536A (en) * 1972-06-08 1974-09-17 Warner Lambert Co 1,2,3,4-tetrahydro-3-aminomethyliso-quinolines
FR2426046A1 (fr) * 1978-05-18 1979-12-14 Synthelabo Derive de tetrahydro-isoquinoleine, sa preparation et son application en therapeutique
US4220778A (en) * 1978-10-30 1980-09-02 G. D. Searle & Co. 8-Aryl-1,2,3,4-tetrahydroisoquinoline and derivatives thereof
US4766131A (en) * 1980-10-17 1988-08-23 Pennwalt Corporation 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
HU201543B (en) 1990-11-28
NO890440D0 (no) 1989-02-03
PT89643B (pt) 1994-02-28
DK50089D0 (da) 1989-02-03
ATE95816T1 (de) 1993-10-15
AU2961789A (en) 1990-01-18
DK50089A (da) 1990-01-13
FI890520A7 (fi) 1990-01-13
EP0351255A2 (fr) 1990-01-17
US4925850A (en) 1990-05-15
AU606778B2 (en) 1991-02-14
KR900001676A (ko) 1990-02-27
DE68909855D1 (de) 1993-11-18
FI890520L (fi) 1990-01-13
IL89156A0 (en) 1989-09-10
HUT50327A (en) 1990-01-29
NO171786B (no) 1993-01-25
PT89643A (pt) 1989-10-04
EP0351255A3 (en) 1990-05-02
NO890440L (no) 1990-01-15
JPH0225481A (ja) 1990-01-26
NZ227853A (en) 1990-06-26
FI890520A0 (fi) 1989-02-03
EP0351255B1 (fr) 1993-10-13
ZA89905B (en) 1989-10-25
NO171786C (no) 1993-05-05

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees