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IL85026A - Serum-free growth medium comprising an iron-chelate and an aurin tricarboxylic acid and use thereof - Google Patents

Serum-free growth medium comprising an iron-chelate and an aurin tricarboxylic acid and use thereof

Info

Publication number
IL85026A
IL85026A IL8502688A IL8502688A IL85026A IL 85026 A IL85026 A IL 85026A IL 8502688 A IL8502688 A IL 8502688A IL 8502688 A IL8502688 A IL 8502688A IL 85026 A IL85026 A IL 85026A
Authority
IL
Israel
Prior art keywords
growth medium
chelate
iron
serum
tricarboxylic acid
Prior art date
Application number
IL8502688A
Other languages
English (en)
Other versions
IL85026A0 (en
Original Assignee
Medi Cult As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medi Cult As filed Critical Medi Cult As
Publication of IL85026A0 publication Critical patent/IL85026A0/xx
Publication of IL85026A publication Critical patent/IL85026A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
IL8502688A 1987-01-09 1988-01-05 Serum-free growth medium comprising an iron-chelate and an aurin tricarboxylic acid and use thereof IL85026A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO870095A NO162160C (no) 1987-01-09 1987-01-09 Serumfritt vekstmedium, samt anvendelse derav.

Publications (2)

Publication Number Publication Date
IL85026A0 IL85026A0 (en) 1988-06-30
IL85026A true IL85026A (en) 1992-09-06

Family

ID=19889567

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8502688A IL85026A (en) 1987-01-09 1988-01-05 Serum-free growth medium comprising an iron-chelate and an aurin tricarboxylic acid and use thereof

Country Status (16)

Country Link
US (2) US5045467A (pt)
EP (1) EP0274445B1 (pt)
JP (2) JPH0697996B2 (pt)
KR (1) KR880009124A (pt)
AT (1) ATE92098T1 (pt)
AU (1) AU596491B2 (pt)
BR (1) BR8800040A (pt)
CA (1) CA1321961C (pt)
DE (1) DE3882540T2 (pt)
DK (1) DK169765B1 (pt)
ES (1) ES2008411A6 (pt)
FI (1) FI87230C (pt)
IL (1) IL85026A (pt)
IT (1) IT1215675B (pt)
NO (1) NO162160C (pt)
NZ (1) NZ223139A (pt)

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CA1307486C (en) * 1987-10-29 1992-09-15 Michael T. Largen Hybridoma production
SE8801537D0 (sv) * 1988-04-26 1988-04-26 Ellco Food Ab Cellodlingsmedium samt forfarande for dess framstellning
JPH03180175A (ja) * 1989-12-07 1991-08-06 Snow Brand Milk Prod Co Ltd 無血清培地
US5378612A (en) * 1990-05-11 1995-01-03 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Culture medium for production of recombinant protein
CA2111984A1 (en) * 1991-06-21 1993-01-07 Peter B. Suhr-Jessen Iron chelate culture medium additive
GB9215834D0 (en) * 1992-07-24 1992-09-09 Celltech Ltd Cell culture
DE4313620A1 (de) * 1993-04-26 1994-10-27 Biotechnolog Forschung Gmbh Hamsterzellinien und Verfahren zur Glykoproteingewinnung
US5434185A (en) * 1993-05-17 1995-07-18 The University Of Kentucky Research Foundation Method for inhibiting angiogenesis with aurintricarboxylic acid, its analogues or salts
US5405772A (en) * 1993-06-18 1995-04-11 Amgen Inc. Medium for long-term proliferation and development of cells
US5846529A (en) * 1993-08-23 1998-12-08 Nexell Therapeutics, Inc. Infusion of neutrophil precursors for treatment of neutropenia
US6037174A (en) * 1993-08-23 2000-03-14 Nexell Therapeutics, Inc. Preparation of serum-free suspensions of human hematopoietic cells or precursor cells
US5395822A (en) * 1993-09-20 1995-03-07 Izumi; Yukitoshi Use of pyruvate to prevent neuronal degeneration associated with ischemia
US5593880A (en) * 1994-02-10 1997-01-14 Viratest International, Inc. Dual-state nutritional medium for the transport and maintenance of cells
US5908782A (en) * 1995-06-05 1999-06-01 Osiris Therapeutics, Inc. Chemically defined medium for human mesenchymal stem cells
AU2260097A (en) * 1996-03-12 1997-10-01 Life Technologies, Inc. Hematopoietic cell culture nutrient supplement
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
US6511848B2 (en) * 1996-04-17 2003-01-28 Winfried Albert Process for producing and multiplying lymphocytes
EP1482031B1 (en) 1996-08-30 2015-10-28 Life Technologies Corporation Serum-free mammalian cell culture medium, and uses thereof
US6833271B2 (en) * 1996-12-04 2004-12-21 Medi-Cult A/S Serum-free cell culture media
GB9625175D0 (en) * 1996-12-04 1997-01-22 Medi Cult As Serum-free cell culture media
US5804420A (en) * 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium
AU2878200A (en) * 1999-02-11 2000-08-29 Schepens Eye Research Institute, Inc., The Growth medium for human corneal endothelial cells
ATE384120T1 (de) * 1999-08-27 2008-02-15 Invitrogen Corp Metallbindende verbindungen und deren verwendung in zusammensetzungen für zellkulturmedien
US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
GB0003231D0 (en) * 2000-02-11 2000-04-05 Medi Cult As Cell culture media
US20030096414A1 (en) * 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
JP2004535189A (ja) * 2001-06-04 2004-11-25 エムエル ラボラトリーズ ピーエルシー 組換えタンパク質の高レベルの大規模生成のための組成物および方法
US7087369B2 (en) * 2003-12-17 2006-08-08 The Regents Of The University Of California Cornea preservation medium
US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
US20080090753A1 (en) * 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
PL1807504T3 (pl) 2004-11-02 2011-07-29 Ares Trading Sa Bezsurowicza pożywka hodowlana dla komórek ssaczych
US8273553B2 (en) 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
ATE547511T1 (de) 2004-12-23 2012-03-15 Medimmune Llc Nichttumorbildende mdck-zellinie zur vermehrung von viren
JP4944112B2 (ja) 2005-08-26 2012-05-30 アレス トレーディング ソシエテ アノニム グリコシル化されたインターフェロンベータの調製方法
WO2007080919A1 (ja) 2006-01-13 2007-07-19 Japan Science And Technology Agency 動物細胞を無血清培養するための培地用添加剤、キット及びこれらの利用
RU2463345C2 (ru) * 2006-07-13 2012-10-10 Вайет Получение гликопротеинов
KR101464783B1 (ko) 2006-09-15 2014-11-26 메디뮨 엘엘씨 높은 역가로 바이러스 증식을 지원하는 ｍｄｃｋ 세포주 및 이를 이용한 생물반응기 공정
WO2009032040A1 (en) 2007-08-29 2009-03-12 Millipore Corporation Serum-free growth medium for acholeplasma laidlawii and methods for retention testing sterilizing grade filters
EP2334328A4 (en) 2008-09-24 2012-08-29 Medimmune Llc METHOD FOR CLEANING VIRUSES
KR101712501B1 (ko) * 2008-11-11 2017-03-07 고쿠리츠다이가쿠호진 히로시마다이가쿠 분화 유도 배지용 첨가제 및 그의 용도
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
DK2545928T3 (en) 2010-03-10 2016-10-03 Two Cells Co Ltd CELL PREPARATION CONTAINING MESENYKYMAL STEM CELLS AND METHOD OF PRODUCING THEREOF
CN109370980B (zh) 2012-05-02 2023-05-09 生命技术公司 高产量瞬时表达系统
EP3122770A4 (en) * 2014-03-23 2017-08-23 Advantech Bioscience Farmacêutica Ltda. Enhancement of recombinant protein expression with copper
TW201630622A (zh) 2014-12-16 2016-09-01 美國禮來大藥廠 速效胰島素組合物
US10119117B2 (en) 2016-01-28 2018-11-06 Nanogen Pharmaceutical Biotechnology Co., Ltd Universal, glycosylation enhancer, completely chemically defined medium formulation
KR102604992B1 (ko) * 2017-03-31 2023-11-24 베링거 인겔하임 인터내셔날 게엠베하 관류 배지
CN110835622B (zh) * 2018-08-16 2021-04-27 上海药明生物技术有限公司 用于调节哺乳动物细胞乳酸代谢的培养基及其应用
WO2025033487A1 (ja) * 2023-08-09 2025-02-13 国立研究開発法人産業技術総合研究所 血清または血清代替物の品質管理方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466917A (en) * 1981-02-12 1984-08-21 New York University Malaria vaccine
US4544632A (en) * 1981-06-12 1985-10-01 Yuichi Yamamura Human T cell lines and method of producing same
IL65765A (en) * 1982-05-13 1985-09-29 Israel State Method of preventing virus replication in plants
US4604284A (en) * 1983-09-20 1986-08-05 Hoffmann-La Roche Inc. Homogeneous immune interferon fragment
EP0156169B1 (en) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
JPS6158584A (ja) * 1984-08-30 1986-03-25 Ube Ind Ltd 細胞増殖促進剤及び細胞増殖促進方法
JP2967117B2 (ja) * 1989-03-14 1999-10-25 旭化成工業株式会社 電子線硬化型導電性ペースト組成物

Also Published As

Publication number Publication date
DK678687D0 (da) 1987-12-22
DE3882540D1 (de) 1993-09-02
FI87230B (fi) 1992-08-31
JP2524313B2 (ja) 1996-08-14
EP0274445A3 (en) 1989-12-13
ES2008411A6 (es) 1989-07-16
NZ223139A (en) 1991-09-25
JPH0697996B2 (ja) 1994-12-07
FI87230C (fi) 1992-12-10
FI875793A0 (fi) 1987-12-31
IT1215675B (it) 1990-02-22
IT8819024A0 (it) 1988-01-08
EP0274445A2 (en) 1988-07-13
JPH06292570A (ja) 1994-10-21
NO870095L (no) 1988-07-11
IL85026A0 (en) 1988-06-30
ATE92098T1 (de) 1993-08-15
DK169765B1 (da) 1995-02-20
EP0274445B1 (en) 1993-07-28
AU1011588A (en) 1988-07-14
KR880009124A (ko) 1988-09-14
JPS63279786A (ja) 1988-11-16
CA1321961C (en) 1993-09-07
FI875793L (fi) 1988-07-10
DE3882540T2 (de) 1993-11-18
US5045467A (en) 1991-09-03
NO162160C (no) 1989-11-15
DK678687A (da) 1988-07-10
US5045454A (en) 1991-09-03
BR8800040A (pt) 1988-08-02
NO870095D0 (no) 1987-01-09
NO162160B (no) 1989-08-07
AU596491B2 (en) 1990-05-03

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees