IL59623A0 - Preparation of 2,5-bus(2,2,2-trifluoro-ethoxy)n-(2-piperidylmethyl)benzamide - Google Patents

Preparation of 2,5-bus(2,2,2-trifluoro-ethoxy)n-(2-piperidylmethyl)benzamide

Info

Publication number: IL59623A0
Authority: IL; Israel
Prior art keywords: piperidylmethyl; benzamide; trifluoro; ethoxy; bus
Prior art date: 1979-03-19

Application number

IL59623A

Other versions

IL59623A (en

Original Assignee

Riker Laboratories Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-19

Filing date

1980-03-14

Publication date

1980-06-30

1980-03-14 Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc

1980-06-30 Publication of IL59623A0 publication Critical patent/IL59623A0/en

1982-12-15 Priority to IL67486A priority Critical patent/IL67486A0/en

1983-07-31 Publication of IL59623A publication Critical patent/IL59623A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL59623A 1979-03-19 1980-03-14 Preparation of 2,5-bis(2,2,2-trifluoroethoxy)-n-(2-piperidylmethyl)benzamide and 2,5-trifluoroethoxyacetophenone intermediates therefor IL59623A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL67486A IL67486A0 (en)	1979-03-19	1982-12-15	Process for the preparation of 1,4-bis(2,2,2-trifluoroethoxy)benzene

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2133179A	1979-03-19	1979-03-19
US2133279A	1979-03-19	1979-03-19

Publications (2)

Publication Number	Publication Date
IL59623A0 true IL59623A0 (en)	1980-06-30
IL59623A IL59623A (en)	1983-07-31

Family

ID=26694559

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL59623A IL59623A (en)	1979-03-19	1980-03-14	Preparation of 2,5-bis(2,2,2-trifluoroethoxy)-n-(2-piperidylmethyl)benzamide and 2,5-trifluoroethoxyacetophenone intermediates therefor

Country Status (14)

Country	Link
JP (8)	JPH01104045A (en)
CA (1)	CA1137486A (en)
CH (1)	CH643829A5 (en)
DE (1)	DE3010195A1 (en)
DK (3)	DK167062B1 (en)
ES (1)	ES8104227A1 (en)
FR (7)	FR2454438A1 (en)
GB (2)	GB2045760B (en)
IE (1)	IE49558B1 (en)
IL (1)	IL59623A (en)
IT (1)	IT1195262B (en)
NL (1)	NL191486C (en)
PT (1)	PT70967A (en)
SE (5)	SE447992B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2519979A1 (en) *	1982-01-21	1983-07-22	Rhone Poulenc Spec Chim	PROCESS FOR THE PREPARATION OF TRIFLUOROMETHOXY OR TRIFLUOROMETHYLTHIOPHENYLSULFONES
FR2519974A1 (en) *	1982-01-21	1983-07-22	Rhone Poulenc Spec Chim	PROCESS FOR THE ACYLATION OF HALOGENO OR TRIHALOGENOMETHYLBENZENES
FR2519975A1 (en) *	1982-01-21	1983-07-22	Rhone Poulenc Spec Chim	PROCESS FOR PREPARING TRIFLUOROMETHOXY OR TRIFLUOROMETHYLTHIOPHENYLCETONES
FR2519980A1 (en) *	1982-01-21	1983-07-22	Rhone Poulenc Spec Chim	PROCESS FOR THE SULFONYLATION OF HALOGENO OR TRIHALOGENOMETHYLBENZENES
FR2525588A1 (en) *	1982-04-22	1983-10-28	Rhone Poulenc Spec Chim	PROCESS FOR PREPARING PHENYLCETONES FROM HALOGENO OR TRIHALOGENOMETHYLBENZENES AND ALIPHATIC OR AROMATIC TRIHALOGENOMETHYL COMPOUNDS
FR2525589A1 (en)	1982-04-22	1983-10-28	Rhone Poulenc Spec Chim	PROCESS FOR PREPARING TRIFLUOROMETHOXY OR TRIFLUOROMETHYLTHIOPHENYLCETONES
EP0175188A1 (en) *	1984-09-11	1986-03-26	Nihon Tokushu Noyaku Seizo K.K.	Carbamoylimidazole derivatives
US4675448A (en) *	1985-02-13	1987-06-23	Ethyl Corporation	Chlorination process
FR2579594B1 (en) *	1985-03-29	1987-06-05	Rhone Poulenc Spec Chim	PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXY OR TRIFLUOROETHYLTHIOBENZENES
FR2579591B1 (en) *	1985-03-29	1988-10-14	Rhone Poulenc Spec Chim	PROCESS FOR THE PREPARATION OF PENTAFLUOROETHOXY AND PENTAFLUOROETHYLTHIOBENZENIQUE DERIVATIVES
NZ219913A (en) *	1986-04-25	1990-08-28	Riker Laboratories Inc	Various flecainide derivatives and antibodies raised thereto
DE3786037T2 (en) *	1986-04-25	1993-11-25	Abbott Lab	Tracer for use in immunological fluorescence polarization methods for the detection of flecainide.
DE3644798A1 (en) *	1986-12-31	1988-07-14	Hoechst Ag	NEW NITROHALOALCOXYBENZOLS, METHOD FOR THEIR PRODUCTION AND THEIR USE
FR2640262B1 (en) *	1988-12-14	1991-05-31	Rhone Poulenc Chimie	PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYLATED ARYLIC KETONES
IL121288A (en)	1997-07-11	2000-10-31	Finetech Ltd	Process and a novel intermediate for the preparation of flecainide
US6316627B1 (en)	1997-04-21	2001-11-13	Fine Tech Ltd.	Process for the preparation of flecainide
IL120715A (en)	1997-04-21	2000-07-16	Finetech Ltd	Process for the preparation of (2,2,2,-trifluoroethoxy)benzoic acids
US7196197B2 (en)	2003-09-17	2007-03-27	Apotex Pharmachem Inc.	Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof
JP4894226B2 (en) *	2005-10-31	2012-03-14	Ｄｉｃ株式会社	Method for producing fluorine-containing liquid crystal compound having hydroquinone skeleton
CN117326927A (en) *	2023-09-28	2024-01-02	清源创新实验室	Preparation method of 2,5-bis (2, 2-trifluoroethoxy) benzoic acid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3539642A (en) *	1967-07-19	1970-11-10	Geigy Chem Corp	2-phenyl-2-(1-naphthyl)acetamides
US3772304A (en) *	1969-10-30	1973-11-13	Hoffmann La Roche	4-hydroxy-isoquinolines and processes for their preparation
US3719687A (en) *	1970-07-22	1973-03-06	Riker Laboratories Inc	N-(2-dialkylaminoalkylene)amides of 1,1-dihydroperfluoroalkoxy-substituted aryl acids and salts thereof
US3655728A (en)	1970-07-22	1972-04-11	Riker Laboratories Inc	N-(2 - dialkylaminoalkylene)-esters of fluoroalkoxy-substituted aryl carboxylic acid and salts thereof
US3967949A (en) *	1973-06-18	1976-07-06	Eli Lilly And Company	Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents
US4169108A (en) *	1973-08-16	1979-09-25	Sterling Drug Inc.	5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols
US3900481A (en) *	1974-04-01	1975-08-19	Riker Laboratories Inc	Derivatives of pyrrolidine and piperidine
US4013670A (en) *	1974-04-01	1977-03-22	Riker Laboratories, Inc.	Derivatives of pyrrolidine and piperidine
US4005209A (en) *	1974-04-01	1977-01-25	Riker Laboratories, Inc.	Antiarrhythmic method utilizing fluoroalkoxy-N-piperidyl and pyridyl benzamides
IL49803A (en) *	1975-06-28	1979-11-30	Fisons Ltd	Preparation of pyrogallol
DE2616478C2 (en) *	1976-04-14	1986-05-22	Brickl, Rolf, Dr., 7951 Warthausen	Medicines, biocides and cosmetics containing fluoroacylresorcins
JPS6023656B2 (en) *	1976-09-02	1985-06-08	川研フアインケミカル株式会社	Method for producing alkoxy aromatic compounds
US4097481A (en) *	1976-11-08	1978-06-27	Riker Laboratories, Inc.	Tertiary amide derivatives of pyrrolidine and piperidine
US4071524A (en) *	1976-11-08	1978-01-31	Riker Laboratories, Inc.	Derivatives of urea

0
- GB GB8214964A patent/GB2097000B/en not_active Expired
1980
- 1980-03-04 CA CA000346919A patent/CA1137486A/en not_active Expired
- 1980-03-14 SE SE8002003A patent/SE447992B/en not_active IP Right Cessation
- 1980-03-14 DK DK112180A patent/DK167062B1/en not_active IP Right Cessation
- 1980-03-14 IL IL59623A patent/IL59623A/en unknown
- 1980-03-16 NL NL8001551A patent/NL191486C/en not_active IP Right Cessation
- 1980-03-17 ES ES489629A patent/ES8104227A1/en not_active Expired
- 1980-03-17 DE DE19803010195 patent/DE3010195A1/en active Granted
- 1980-03-18 IE IE549/80A patent/IE49558B1/en not_active IP Right Cessation
- 1980-03-18 PT PT70967A patent/PT70967A/en active IP Right Revival
- 1980-03-18 CH CH212880A patent/CH643829A5/en not_active IP Right Cessation
- 1980-03-18 FR FR8006019A patent/FR2454438A1/en active Granted
- 1980-03-18 GB GB8009041A patent/GB2045760B/en not_active Expired
- 1980-03-18 IT IT20746/80A patent/IT1195262B/en active Protection Beyond IP Right Term
1981
- 1981-01-07 FR FR8100142A patent/FR2468571A1/en active Granted
- 1981-01-07 FR FR8100141A patent/FR2468570A1/en active Granted
- 1981-01-07 FR FR8100143A patent/FR2468576A1/en active Granted
- 1981-01-07 FR FR8100145A patent/FR2468591A1/en active Granted
- 1981-01-07 FR FR8100144A patent/FR2468590A1/en active Granted
- 1981-01-07 FR FR8100140A patent/FR2468569A1/en active Granted
1984
- 1984-03-21 SE SE8401555A patent/SE463260B/en not_active IP Right Cessation
- 1984-03-21 SE SE8401554A patent/SE447993B/en not_active IP Right Cessation
1988
- 1988-06-01 JP JP63135363A patent/JPH01104045A/en active Granted
- 1988-06-01 JP JP63135370A patent/JPH01125344A/en active Granted
- 1988-06-01 JP JP63135365A patent/JPH01104044A/en active Granted
- 1988-06-01 JP JP63135364A patent/JPH01104043A/en active Granted
- 1988-06-01 JP JP63135369A patent/JPH01125343A/en active Granted
- 1988-06-01 JP JP63135367A patent/JPH01125341A/en active Granted
- 1988-06-01 JP JP63135368A patent/JPH01125342A/en active Granted
- 1988-06-01 JP JP63135366A patent/JPH01125339A/en active Granted
1989
- 1989-04-27 SE SE8901532A patent/SE463418B/en not_active IP Right Cessation
- 1989-04-27 SE SE8901533A patent/SE463419B/en not_active IP Right Cessation
1990
- 1990-05-17 DK DK122290A patent/DK164857C/en not_active IP Right Cessation
1991
- 1991-04-30 DK DK079891A patent/DK79891A/en unknown

Also Published As

Publication number	Publication date
GB2097000A (en)	1982-10-27
SE8002003L (en)	1980-09-20
FR2468571B1 (en)	1983-03-11
NL8001551A (en)	1980-09-23
FR2468590A1 (en)	1981-05-08
FR2468576A1 (en)	1981-05-08
JPH01104045A (en)	1989-04-21
FR2454438A1 (en)	1980-11-14
GB2045760A (en)	1980-11-05
SE463418B (en)	1990-11-19
SE8901533D0 (en)	1989-04-27
IL59623A (en)	1983-07-31
JPH01104044A (en)	1989-04-21
SE8401554D0 (en)	1984-03-21
CH643829A5 (en)	1984-06-29
JPH01125341A (en)	1989-05-17
FR2468591B1 (en)	1983-07-22
IE49558B1 (en)	1985-10-30
ES489629A0 (en)	1981-04-01
DK79891D0 (en)	1991-04-30
JPH01125339A (en)	1989-05-17
JPH0251908B2 (en)	1990-11-08
DE3010195A1 (en)	1980-10-02
SE447992B (en)	1987-01-12
FR2468591A1 (en)	1981-05-08
IT8020746A0 (en)	1980-03-18
FR2468570B1 (en)	1983-03-11
DK112180A (en)	1980-09-20
JPH0251906B2 (en)	1990-11-08
SE8901532L (en)	1989-04-27
DK122290D0 (en)	1990-05-17
SE463419B (en)	1990-11-19
IE800549L (en)	1980-09-19
ES8104227A1 (en)	1981-04-01
JPH01125343A (en)	1989-05-17
FR2468569B1 (en)	1983-03-11
DK122290A (en)	1990-05-17
IT1195262B (en)	1988-10-12
JPH022870B2 (en)	1990-01-19
SE463260B (en)	1990-10-29
JPH0339498B2 (en)	1991-06-14
SE8401555D0 (en)	1984-03-21
NL191486B (en)	1995-04-03
SE8401555L (en)	1984-03-21
SE8401554L (en)	1984-03-21
FR2454438B1 (en)	1982-07-23
JPH0251907B2 (en)	1990-11-08
FR2468571A1 (en)	1981-05-08
FR2468570A1 (en)	1981-05-08
JPH01125342A (en)	1989-05-17
DK164857B (en)	1992-08-31
NL191486C (en)	1995-08-04
FR2468590B1 (en)	1983-09-23
DK164857C (en)	1993-01-18
GB2097000B (en)	1983-11-30
CA1137486A (en)	1982-12-14
JPH022869B2 (en)	1990-01-19
FR2468569A1 (en)	1981-05-08
DK167062B1 (en)	1993-08-23
PT70967A (en)	1980-04-01
DE3010195C2 (en)	1990-10-25
SE8901533L (en)	1989-04-27
JPH0372212B2 (en)	1991-11-18
JPH0149695B2 (en)	1989-10-25
JPH01104043A (en)	1989-04-21
GB2045760B (en)	1983-05-11
JPH01125344A (en)	1989-05-17
SE8901532D0 (en)	1989-04-27
SE447993B (en)	1987-01-12
FR2468576B1 (en)	1983-01-21
DK79891A (en)	1991-04-30

Publication	Publication Date	Title
IL59623A0 (en)	1980-06-30	Preparation of 2,5-bus(2,2,2-trifluoro-ethoxy)n-(2-piperidylmethyl)benzamide
PH19006A (en)	1985-12-03	Process for the preparation of new optically active 1,4-dihydropyridine
PT74923B (en)	1986-11-13	Process for preparing 1,2-diaminocyclobutene-3,4-di ones substituted and pharmaceutical compositions therewith
IL60546A (en)	1983-09-30	Preparation of 2,6-dialkylcyclohexylamines
PT84127B (en)	1989-01-24	Process for the preparation of 1,2-disubstituted piperidines and of herbicide compositions containing the same
IL51149A (en)	1980-03-31	N-(1,3,4-thiadiazol-2yl)benzamide derivatives process for their preparation and insecticidal composition containing them
ZA872429B (en)	1987-11-25	N-substituted benzamides
GB2048868B (en)	1983-05-25	Preparation of 2',6'-dialkyl - n - alkoxymethyl - 2 - chloroacetanilides
IL52645A (en)	1980-02-29	Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides
DE2961373D1 (en)	1982-01-28	Process for the preparation of n-substituted 2,6-dialkyl anilines
NZ186425A (en)	1980-04-28	1,3-disubstituted ureas and 2-thioureas also pharmaceutical compositions containing them
IL57464A (en)	1983-10-31	N-(phenylcarbamoyl)benzimidates,process for their preparation and insecticidal compositions containing them
ZA802777B (en)	1981-06-24	N-(2,5-diazolyl)-alkyl-halogenoacetanilides, processes for their preparation and their use as herbicides
IL63217A (en)	1985-03-31	N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzamide,its preparation and pharmaceutical compositions containing it
PT79823B (en)	1987-01-07	Process for the preparation of n-(naphtyl-alquil)-hydroxilamines
IL60633A0 (en)	1980-09-16	Preparation of 1,1-dichloroalkenes
GB2058775B (en)	1983-05-05	Preparation of 2,5-diketogluconic acid
HK12283A (en)	1983-04-07	N-(1,3,4-thiadiazol-2-4l)benzamides
JPS6416755A (en)	1989-01-20	Manufacture of n-(3',4'-dimethoxycinnamoyl)-aniline derivative
ZA801565B (en)	1981-05-27	Process for the preparation of 2,5-bis(2,2,2-trifluoroethoxy)-n-(2-piperidylmethyl)benzamide
DE2960313D1 (en)	1981-08-06	N-(o-ethyl-s-n-propyl-(di)thiophosphoryloxy)-naphtalimides, process for their preparation, pesticidal compositions containing them, their preparation and use
GB2060631B (en)	1983-07-20	Preparation of 2-oxo-dihydrobenzo-(d)(1,3)-oxazines
GB2067190B (en)	1984-03-14	Preparation of 1,3,5-trichlorobenzene
GB2044768B (en)	1983-03-16	Preparation of 1,1,1,4,4,4,-hexofluorobutyne
DE3161273D1 (en)	1983-12-01	Process for the preparation of n-(1'-alkoxycarbonylethyl)-2,6-dialkyl anilines

Legal Events

Date	Code	Title	Description
1998-09-24	KB	Patent renewed