[go: up one dir, main page]

IL155624A0 - Novel imidazole derivatives, production method thereof and use thereof - Google Patents

Novel imidazole derivatives, production method thereof and use thereof

Info

Publication number
IL155624A0
IL155624A0 IL15562401A IL15562401A IL155624A0 IL 155624 A0 IL155624 A0 IL 155624A0 IL 15562401 A IL15562401 A IL 15562401A IL 15562401 A IL15562401 A IL 15562401A IL 155624 A0 IL155624 A0 IL 155624A0
Authority
IL
Israel
Prior art keywords
production method
imidazole derivatives
novel imidazole
novel
derivatives
Prior art date
Application number
IL15562401A
Other languages
English (en)
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL155624A0 publication Critical patent/IL155624A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
IL15562401A 2000-11-17 2001-11-16 Novel imidazole derivatives, production method thereof and use thereof IL155624A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000351780 2000-11-17
JP2001247618 2001-08-17
JP2001336880 2001-11-01
PCT/JP2001/010002 WO2002040484A2 (en) 2000-11-17 2001-11-16 Novel imidazole derivatives, production method thereof and use thereof

Publications (1)

Publication Number Publication Date
IL155624A0 true IL155624A0 (en) 2003-11-23

Family

ID=27345219

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15562401A IL155624A0 (en) 2000-11-17 2001-11-16 Novel imidazole derivatives, production method thereof and use thereof
IL155624A IL155624A (en) 2000-11-17 2003-04-28 History 7,6 - Dihydro - 5 H - Pyrrolo [2,1 - c] Imidazole - 7 - All converted in position 7 and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155624A IL155624A (en) 2000-11-17 2003-04-28 History 7,6 - Dihydro - 5 H - Pyrrolo [2,1 - c] Imidazole - 7 - All converted in position 7 and pharmaceutical preparations containing them

Country Status (26)

Country Link
US (1) US7141598B2 (es)
EP (2) EP1681290B9 (es)
JP (2) JP3753971B2 (es)
KR (3) KR100809899B1 (es)
CN (3) CN100572363C (es)
AR (1) AR034854A1 (es)
AT (2) ATE533768T1 (es)
AU (3) AU2002214296C1 (es)
BR (1) BR0115306B1 (es)
CA (1) CA2429133C (es)
CY (1) CY1105423T1 (es)
DE (1) DE60119963T2 (es)
DK (1) DK1334106T3 (es)
ES (1) ES2260303T3 (es)
HU (1) HU229408B1 (es)
IL (2) IL155624A0 (es)
MX (1) MXPA03004347A (es)
MY (1) MY134929A (es)
NO (1) NO326366B1 (es)
NZ (1) NZ526387A (es)
PE (1) PE20020596A1 (es)
PL (1) PL204934B1 (es)
PT (1) PT1334106E (es)
SI (1) SI1334106T1 (es)
TW (1) TWI306099B (es)
WO (1) WO2002040484A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1471056B1 (en) * 2002-01-10 2012-07-11 Takeda Pharmaceutical Company Limited Process for producing fused imidazole compound, reformatsky reagent in stable form, and process for producing the same
JP4745616B2 (ja) * 2003-02-26 2011-08-10 武田薬品工業株式会社 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾール誘導体の安定化方法
WO2004075890A1 (ja) * 2003-02-26 2004-09-10 Takeda Pharmaceutical Company 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾ－ル誘導体の安定化方法
CA2519211A1 (en) * 2003-03-17 2004-09-30 Takeda Pharmaceutical Company Limited Release control compositions
JP4837895B2 (ja) * 2003-03-17 2011-12-14 武田薬品工業株式会社 放出制御組成物
US7282507B2 (en) * 2004-05-03 2007-10-16 Janssen Pharmaceutica N.V. Indole derivatives as selective androgen receptor modulators (SARMS)
AR049125A1 (es) * 2004-05-28 2006-06-28 Speedel Experimenta Ag Heterociclos biciclicos nitrogenados inhibidores de la aromatasa.
US8828429B2 (en) 2005-03-03 2014-09-09 Takeda Pharmaceutical Company Limited Release-control composition
GT200600381A (es) * 2005-08-25 2007-03-28 Compuestos organicos
TW200804378A (en) 2005-12-09 2008-01-16 Speedel Experimenta Ag Organic compounds
JP5230448B2 (ja) * 2006-02-10 2013-07-10 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 選択的アンドローゲン受容体モジュレーターとして有用な新イミダゾロピラゾール誘導体
AR060225A1 (es) * 2006-03-31 2008-06-04 Speedel Experimenta Ag Proceso para preparar 6,7- dihidro-5h-imidazo (1,5-a) piridin -8- ona
AU2008319767B8 (en) * 2007-10-29 2014-01-09 Takeda Pharmaceutical Company Limited Pyrrolo [1,2-C] imidazole derivatives for use in the prophylaxis or treatment of cancer which is refractory to known cancer therapies
JOP20190230A1 (ar) 2009-01-15 2017-06-16 Incyte Corp طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به
UY33740A (es) * 2010-11-18 2012-05-31 Takeda Pharmaceutical Método para tratar el cáncer de mama y cáncer de ovarios
EA201391447A1 (ru) 2011-04-01 2014-02-28 Такеда Фармасьютикал Компани Лимитед Твердая композиция
CA2838971C (en) 2011-06-15 2019-07-30 Takeda Pharmaceutical Company Limited Production method of imidazole derivatives

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
NZ221729A (en) 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
AU606677B2 (en) 1987-04-22 1991-02-14 Merrell Dow Pharmaceuticals Inc. 17 beta -(cyclopropylimino) androst-5-EN-3 beta- Ol and related compounds useful as C17-20 lyase inhibitors
US5057521A (en) * 1988-10-26 1991-10-15 Ciba-Geigy Corporation Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
US4966898A (en) 1989-08-15 1990-10-30 Merrell Dow Pharmaceuticals Inc. 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
WO1992015404A1 (en) 1991-03-01 1992-09-17 S.L. Electrostatic Technology, Inc. Powder coating method for producing circuit board laminae and the like
US5457102A (en) 1994-07-07 1995-10-10 Janssen Pharmaceutica, N.V. Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives
PT625155E (pt) * 1992-01-27 2002-01-30 Janssen Pharmaceutica Nv Derivados de 1h-benzimidazol substituidos por pirrolo-imidazolilo e imidazopiridinilo utilizados como inibidores de aromatase
CA2132449C (en) 1992-03-31 2002-09-10 Susan E. Barrie 17 - substituted steroids useful in cancer treatment
GB9310635D0 (en) 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
HUT75871A (en) 1993-09-30 1997-05-28 Yamanouchi Co Azole derivatives and pharmaceutical compositions thereof
WO1996014090A1 (en) 1994-11-07 1996-05-17 Janssen Pharmaceutica N.V. Compositions comprising carbazoles and cyclodextrins
AU6015796A (en) 1995-06-14 1997-01-15 Yamanouchi Pharmaceutical Co., Ltd. Fused imidazole derivatives and medicinal composition thereof
CA2281598A1 (en) 1997-02-21 1998-08-27 Tetsuya Aono Fused ring compounds, process for producing the same and use thereof
ATE264304T1 (de) 1997-10-02 2004-04-15 Daiichi Seiyaku Co Dihydronaphthalinderivate und verfahren zur herstellung derselben
US6573289B1 (en) 1998-04-23 2003-06-03 Takeda Chemical Industries, Ltd. Naphthalene derivatives, their production and use
PE20010781A1 (es) * 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion

Also Published As

Publication number Publication date
DE60119963D1 (de) 2006-06-29
HK1056168A1 (en) 2004-02-06
NO20032234D0 (no) 2003-05-16
JP2003201282A (ja) 2003-07-18
EP1681290B9 (en) 2013-06-19
CN1680336A (zh) 2005-10-12
JP2006045239A (ja) 2006-02-16
HUP0400549A2 (hu) 2004-06-28
NZ526387A (en) 2004-02-27
HUP0400549A3 (en) 2004-09-28
BR0115306A (pt) 2004-02-10
PE20020596A1 (es) 2002-08-13
PT1334106E (pt) 2006-08-31
ATE327237T1 (de) 2006-06-15
WO2002040484A3 (en) 2002-09-26
KR20030048156A (ko) 2003-06-18
KR20050105287A (ko) 2005-11-03
EP1681290A2 (en) 2006-07-19
PL362766A1 (en) 2004-11-02
AU2005225035A1 (en) 2005-11-10
CA2429133A1 (en) 2002-05-23
US7141598B2 (en) 2006-11-28
EP1681290A3 (en) 2006-07-26
CN1900079A (zh) 2007-01-24
AU2002214296C1 (en) 2006-04-13
CN1329394C (zh) 2007-08-01
ATE533768T1 (de) 2011-12-15
NO326366B1 (no) 2008-11-17
TWI306099B (en) 2009-02-11
EP1681290B1 (en) 2011-11-16
PL204934B1 (pl) 2010-02-26
AU2005225035B2 (en) 2007-02-22
AU1429602A (en) 2002-05-27
KR100809899B1 (ko) 2008-03-10
CN100572363C (zh) 2009-12-23
HU229408B1 (hu) 2013-12-30
WO2002040484A2 (en) 2002-05-23
AU2002214296B2 (en) 2005-09-29
KR20080002929A (ko) 2008-01-04
ES2260303T3 (es) 2006-11-01
US20040033935A1 (en) 2004-02-19
EP1334106B1 (en) 2006-05-24
JP3753971B2 (ja) 2006-03-08
BR0115306B1 (pt) 2013-12-24
MXPA03004347A (es) 2004-05-04
CA2429133C (en) 2009-08-18
KR100725442B1 (ko) 2007-06-07
DE60119963T2 (de) 2006-10-05
NO20032234L (no) 2003-07-16
CN1474819A (zh) 2004-02-11
SI1334106T1 (sl) 2006-10-31
CY1105423T1 (el) 2010-04-28
AR034854A1 (es) 2004-03-24
IL155624A (en) 2006-12-31
DK1334106T3 (da) 2006-09-18
MY134929A (en) 2008-01-31
EP1334106A2 (en) 2003-08-13
JP4427496B2 (ja) 2010-03-10

Similar Documents

Publication Publication Date Title
PL365787A1 (en) Heterocyclic compounds, their production and use
HRP20040930A2 (en) Acyl-4-carboxyphenylurea derivatives, method for production and use thereof
PL347885A1 (en) Azepinoindole derivatives, the production and use thereof
HUP0303715A3 (en) Aqueous adhesive system, method for the production and use thereof
AU1429602A (en) Novel imidazole derivatives, production method thereof and use thereof
PL350190A1 (en) Epothilon derivatives, method for the production and the use thereof as pharmaceuticals
HUP0302295A3 (en) Thienodibenzoazulene derivatives, process for their preparation and use thereof
IL161893A0 (en) 5-Phenylpyrimidines, agents comprising the same, method for production and use thereof
PL366168A1 (en) Impregnate, method for the production and use thereof
HUP0302065A3 (en) Chromanone derivatives, production and use thereof
PL371317A1 (en) Acyl-3-carboxyphenylurea derivatives, method for production and use thereof
IL151082A0 (en) Thienopyridine derivatives, their production and use
AU2001295579A1 (en) Pants and method for the production thereof
AU2796602A (en) Coniosetin and derivatives thereof, method for producing the same and use thereof
IL152612A0 (en) Cyclipostins, a method for their production and the use of the same
AU2002227966A1 (en) Coniosetin and derivatives thereof, method for producing the same and use thereof
AU2001262229A1 (en) Cyclipostins, a method for their production and the use of the same
HU0001397D0 (en) 3-amino-3-arylpropan-1-ol derivatives, production and use thereof
IL157793A0 (en) Caloporoside derivatives, methods for the production thereof and their use
AU2795202A (en) Klainetin and derivatives thereof, method for their production and the use of the same
AU2003264894A8 (en) Novel method for preparing alpha-glycosylceramides, novel alpha-glycosylceramide derivatives and their uses
AU6730001A (en) Component, method for production and use thereof
AU2002227952A1 (en) Klainetin and derivatives thereof, method for their production and the use of the same
IL151216A0 (en) Pluraflavins and derivatives thereof, process for their preparation and use thereof
PL347407A1 (en) Method of obtaining derivatives of 5,6,7,8-tetrahydronaphtalen-2-ole

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed