[go: up one dir, main page]

IL154059A0 - Zinc finger domain recognition code and uses thereof - Google Patents

Zinc finger domain recognition code and uses thereof

Info

Publication number
IL154059A0
IL154059A0 IL15405901A IL15405901A IL154059A0 IL 154059 A0 IL154059 A0 IL 154059A0 IL 15405901 A IL15405901 A IL 15405901A IL 15405901 A IL15405901 A IL 15405901A IL 154059 A0 IL154059 A0 IL 154059A0
Authority
IL
Israel
Prior art keywords
zinc finger
recognition code
finger domain
domain recognition
code
Prior art date
Application number
IL15405901A
Other languages
English (en)
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of IL154059A0 publication Critical patent/IL154059A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Collating Specific Patterns (AREA)
  • Enzymes And Modification Thereof (AREA)
IL15405901A 2000-07-21 2001-07-19 Zinc finger domain recognition code and uses thereof IL154059A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22006000P 2000-07-21 2000-07-21
PCT/EP2001/008367 WO2002008286A2 (en) 2000-07-21 2001-07-19 Zinc finger domain recognition code and uses thereof

Publications (1)

Publication Number Publication Date
IL154059A0 true IL154059A0 (en) 2003-07-31

Family

ID=22821881

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15405901A IL154059A0 (en) 2000-07-21 2001-07-19 Zinc finger domain recognition code and uses thereof

Country Status (9)

Country Link
US (2) US20040091878A1 (xx)
EP (1) EP1303608A2 (xx)
JP (1) JP2004519211A (xx)
AR (1) AR034129A1 (xx)
AU (1) AU2001278496A1 (xx)
CA (1) CA2416664A1 (xx)
IL (1) IL154059A0 (xx)
WO (1) WO2002008286A2 (xx)
ZA (1) ZA200300651B (xx)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057308A2 (en) * 2001-01-22 2002-07-25 Sangamo Biosciences, Inc. Zinc finger polypeptides and their use
SI1546322T1 (sl) * 2002-07-24 2011-05-31 Manoa Biosciences Inc Vektorji na osnovi transpozona in metode integracije nukleinskih kislin
WO2004069994A2 (en) * 2003-02-10 2004-08-19 Max-Delbrück-Centrum Für Molekulare Medizin (Mdc) Transposon-based targeting system
ATE497540T1 (de) * 2003-02-10 2011-02-15 Max Delbrueck Centrum Transposon-system zur gezielten integration
ATE536419T1 (de) 2003-02-10 2011-12-15 Max Delbrueck Centrum Transposon basiertes targeting- system
KR20060054196A (ko) * 2003-06-10 2006-05-22 주식회사 툴젠 전달가능한 dna-결합 단백질
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US8133733B2 (en) * 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
EP2418281B1 (en) * 2003-10-24 2016-06-01 Gencia Corporation Methods and compositions for delivering polynucleotides
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US8507277B2 (en) * 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
GB0328448D0 (en) * 2003-12-09 2004-01-14 Univ Leeds Agents for the regulation of transcription via zinc finger proteins
EP1707575A1 (de) * 2005-04-01 2006-10-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Ligation synthetischer Zinkfinger-Peptide zu seriellen Bindeproteinen für die spezifische Adressierung doppelstrangiger DNA-Bereiche (Zinkfinger-Sonden)
WO2007024029A1 (en) * 2005-08-26 2007-03-01 Kyoto University Antiviral agent and viral replication inhibitor
WO2007102618A1 (en) * 2006-03-08 2007-09-13 Kyoto University Nucleic acid cleaving agent
GB0607063D0 (en) 2006-04-07 2006-05-17 Cellcentric Ltd Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
US7977535B2 (en) 2006-07-12 2011-07-12 Board Of Trustees Of Michigan State University DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants
PT2205749T (pt) * 2007-09-27 2016-07-20 Dow Agrosciences Llc Proteínas de dedo de zinco modificadas por engenharia que visam genes de 5-enolpiruvil-chiquimato-3-fosfato-sintase
US20100316702A1 (en) * 2008-01-08 2010-12-16 The Regents Of The University Of California Compositions and methods for regulating erythropoeitin expression and ameliorating anemia and stimulating erythropoiesis
US10316288B2 (en) * 2008-04-30 2019-06-11 Sanbio, Inc. Neural regenerating cells with alterations in DNA methylation
EP2130836B1 (en) * 2008-06-03 2013-02-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Means and methods for producing zinc fingers and concatemers thereof
EP2461819A4 (en) * 2009-07-28 2013-07-31 Sangamo Biosciences Inc METHODS AND COMPOSITIONS FOR TREATING TRI-NUCLEOTIDE REPEAT DISORDERS
CN103003425A (zh) * 2010-06-07 2013-03-27 世良贵史 双生病毒复制抑制剂
US9746475B2 (en) 2011-03-14 2017-08-29 University Of Southern California Antibody and antibody mimetic for visualization and ablation of endogenous proteins
IL293650B2 (en) 2011-09-21 2024-10-01 Sangamo Therapeutics Inc Methods and compositions for regulation of transgene expression
JP2015013810A (ja) * 2011-10-27 2015-01-22 貴史 世良 ジェミニウイルス複製阻害剤
US10689643B2 (en) 2011-11-22 2020-06-23 Active Motif, Inc. Targeted transposition for use in epigenetic studies
MX374399B (es) 2012-02-29 2025-03-06 Sangamo Biosciences Inc Composiciones y sus usos para tratar y prevenir la enfermedad de huntington.
US9890364B2 (en) * 2012-05-29 2018-02-13 The General Hospital Corporation TAL-Tet1 fusion proteins and methods of use thereof
EP4074330A1 (en) * 2013-09-05 2022-10-19 Massachusetts Institute of Technology Tuning microbial populations with programmable nucleases
WO2015070212A1 (en) 2013-11-11 2015-05-14 Sangamo Biosciences, Inc. Methods and compositions for treating huntington's disease
KR102816410B1 (ko) * 2019-02-13 2025-06-04 프로바이오겐 아게 향상된 삽입 부위 선택 특성을 지닌 트랜스포사제(transposase)
WO2021101980A1 (en) * 2019-11-19 2021-05-27 The Regents Of The University Of California Compositions and methods of using engineered fusion proteins that bind g4c2 human repeats
CN113368253B (zh) * 2020-03-10 2022-06-10 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 基于沸石咪唑框架结构的药物载体及其制备方法与应用
WO2024026232A1 (en) * 2022-07-27 2024-02-01 Pioneer Hi-Bred International, Inc Guide rna trapped genome editing

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763209A (en) * 1988-09-26 1998-06-09 Arch Development Corporation Methods and materials relating to the functional domains of DNA binding proteins
EP0475779A1 (en) * 1990-09-14 1992-03-18 Vittal Mallya Scientific Research Foundation Process for the separation of proteins, polypeptides or metals using immobilized, optionally modified, phosvitin
JPH06505152A (ja) * 1990-12-21 1994-06-16 ザ ロックフェラー ユニヴァーシティ 肝集積性転写因子
US5792640A (en) * 1992-04-03 1998-08-11 The Johns Hopkins University General method to clone hybrid restriction endonucleases using lig gene
US5436150A (en) * 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5916794A (en) * 1992-04-03 1999-06-29 Johns Hopkins University Methods for inactivating target DNA and for detecting conformational change in a nucleic acid
US6107059A (en) * 1992-04-29 2000-08-22 Affymax Technologies N.V. Peptide library and screening method
AU684524B2 (en) * 1993-06-14 1997-12-18 Tet Systems Holding Gmbh & Co. Kg Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
CA2181548C (en) * 1994-01-18 2009-11-03 Carlos F. Barbas, Iii Zinc finger protein derivatives and methods therefor
US6140466A (en) * 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
US5837692A (en) * 1994-04-07 1998-11-17 Mercola; Dan Inhibition of the mitogenic activity of PDGF by mammalian EGr
US5972643A (en) * 1994-06-17 1999-10-26 Fred Hutchinson Cancer Research Center Isolated polynucleotide molecules encoding CTCF, a CCCTC-binding factor
US5831008A (en) * 1994-08-18 1998-11-03 La Jolla Cancer Research Foundation Retinoblastoma protein-interacting zinc finger proteins
GB9824544D0 (en) * 1998-11-09 1999-01-06 Medical Res Council Screening system
AU698152B2 (en) * 1994-08-20 1998-10-22 Gendaq Limited Improvements in or relating to binding proteins for recognition of DNA
US6008190A (en) * 1994-12-15 1999-12-28 California Institute Of Technology Cobalt Schiff base compounds
US5789538A (en) * 1995-02-03 1998-08-04 Massachusetts Institute Of Technology Zinc finger proteins with high affinity new DNA binding specificities
US6218522B1 (en) * 1996-03-19 2001-04-17 Shionogi & Co., Ltd. DNA molecule relating to suppression of gene expression and novel protein
US6090783A (en) * 1995-03-24 2000-07-18 Shionogi & Co., Ltd. DNA molecule relating to suppression of gene expression and novel protein
US5891418A (en) * 1995-06-07 1999-04-06 Rhomed Incorporated Peptide-metal ion pharmaceutical constructs and applications
CN1192106C (zh) * 1995-06-23 2005-03-09 丹尼斯科成分公司(丹尼斯科公司) 分离突变体及克隆互补基因的新方法
US6017734A (en) * 1995-07-07 2000-01-25 The Texas A & M University System Unique nucleotide and amino acid sequence and uses thereof
US5770720A (en) * 1995-08-30 1998-06-23 Barnes-Jewish Hospital Ubiquitin conjugating enzymes having transcriptional repressor activity
US5981217A (en) * 1995-12-11 1999-11-09 Mayo Foundation For Medical Education And Research DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts
US5905146A (en) * 1996-03-15 1999-05-18 University Of Arkansas DNA binding protein S1-3
US5928955A (en) * 1996-03-22 1999-07-27 California Institute Of Technology Peptidyl fluorescent chemosensor for divalent zinc
US5928941A (en) * 1996-10-07 1999-07-27 President And Fellows Of Harvard College Repressor kruppel-like factor
US5869250A (en) * 1996-12-02 1999-02-09 The University Of North Carolina At Chapel Hill Method for the identification of peptides that recognize specific DNA sequences
US6235538B1 (en) * 1997-03-05 2001-05-22 The Board Of Regents Of The University Of Oklahoma Test for detecting substances which alter the conformational structure of zinc fingers
GB9710809D0 (en) * 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
GB9710807D0 (en) * 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
WO1999010510A2 (en) * 1997-08-26 1999-03-04 Ariad Gene Therapeutics, Inc. Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain
US6153383A (en) * 1997-12-09 2000-11-28 Verdine; Gregory L. Synthetic transcriptional modulators and uses thereof
US6410248B1 (en) * 1998-01-30 2002-06-25 Massachusetts Institute Of Technology General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
IL137952A0 (en) * 1998-02-20 2001-10-31 Genome Dynamics Inc Method for designing dna-binding proteins of the zinc-finger class
ATE336578T1 (de) * 1998-03-17 2006-09-15 Gendaq Ltd Nukleinsäurebindungsproteine
US6100035A (en) * 1998-07-14 2000-08-08 Cistem Molecular Corporation Method of identifying cis acting nucleic acid elements
US6140081A (en) * 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
US6453242B1 (en) * 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
US6534261B1 (en) * 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
AU2001252428A1 (en) * 2000-05-08 2001-11-20 Gendaq Limited Nucleic acid binding polypeptides

Also Published As

Publication number Publication date
WO2002008286A2 (en) 2002-01-31
US20040091878A1 (en) 2004-05-13
ZA200300651B (en) 2003-11-11
JP2004519211A (ja) 2004-07-02
CA2416664A1 (en) 2002-01-31
EP1303608A2 (en) 2003-04-23
AU2001278496A1 (en) 2002-02-05
US20030134350A1 (en) 2003-07-17
AR034129A1 (es) 2004-02-04
WO2002008286A3 (en) 2002-07-11

Similar Documents

Publication Publication Date Title
IL154059A0 (en) Zinc finger domain recognition code and uses thereof
AU2003205343A1 (en) Zinc finger domain recognition code and uses thereof
GB2357335B (en) Fingerprint recognition and pointing device
AU5323201A (en) Systems and methods for recognizing preferred wagerers
GB0108491D0 (en) Engineering zinc fingers
EP1252601A4 (en) GRAPHIC USER INTERFACE FOR MANUSCRIPTED WRITING RECOGNITION
AU4351201A (en) Heparinase iii and uses thereof
EP1408978A4 (en) NOVEL PHENYLAMINO-PYRIMIDINES AND THEIR USE
EG23266A (en) Shrink resistant and wrinkle free textilles.
EP1368051A4 (en) UROCORTINE III AND SOME OF ITS USES
GB2366399B (en) Recognition of command related items in object code
EP1380006A4 (en) DEVICE FOR RECORDING AND RECOGNIZING MANUSCRIPTED CHARACTERS
EP1408985A4 (en) NEW PYRIDOPYRIMIDONE AND ITS USES
MXPA03007596A (es) Lacas de poliuretano de 1c de secado al horno y su uso.
AU2001284468A1 (en) Dot code and dot code reader
AU3979300A (en) Handwriting coding and recognition
GB0112469D0 (en) Data recognition and retrieval
AU2001229959A1 (en) Novel polypeptide---human zinc finger protein 57 containing bola structural domain and polynucleotide encoding it
AU2001293631A1 (en) A new polypeptide- human zinc finger protein fpm315-17 and the polynucleotide encoding it
AU2001264701A1 (en) Idea capture and evaluation
AU2003299520A8 (en) Urocortin-deficient mice and uses thereof
TW425838U (en) Finger cover
GB0009820D0 (en) A person or object locating and personal information system
AU2002212053A1 (en) A new polypeptide- human zinc finger protein 12.98 and the polynucloetide encoding it
AU2001249688A1 (en) Human leucine-rich repeat family member and uses thereof