IL154059A0 - Zinc finger domain recognition code and uses thereof - Google Patents
Zinc finger domain recognition code and uses thereofInfo
- Publication number
- IL154059A0 IL154059A0 IL15405901A IL15405901A IL154059A0 IL 154059 A0 IL154059 A0 IL 154059A0 IL 15405901 A IL15405901 A IL 15405901A IL 15405901 A IL15405901 A IL 15405901A IL 154059 A0 IL154059 A0 IL 154059A0
- Authority
- IL
- Israel
- Prior art keywords
- zinc finger
- recognition code
- finger domain
- domain recognition
- code
- Prior art date
Links
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title 1
- 239000011701 zinc Substances 0.000 title 1
- 229910052725 zinc Inorganic materials 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Collating Specific Patterns (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22006000P | 2000-07-21 | 2000-07-21 | |
| PCT/EP2001/008367 WO2002008286A2 (en) | 2000-07-21 | 2001-07-19 | Zinc finger domain recognition code and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL154059A0 true IL154059A0 (en) | 2003-07-31 |
Family
ID=22821881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15405901A IL154059A0 (en) | 2000-07-21 | 2001-07-19 | Zinc finger domain recognition code and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20040091878A1 (xx) |
| EP (1) | EP1303608A2 (xx) |
| JP (1) | JP2004519211A (xx) |
| AR (1) | AR034129A1 (xx) |
| AU (1) | AU2001278496A1 (xx) |
| CA (1) | CA2416664A1 (xx) |
| IL (1) | IL154059A0 (xx) |
| WO (1) | WO2002008286A2 (xx) |
| ZA (1) | ZA200300651B (xx) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002057308A2 (en) * | 2001-01-22 | 2002-07-25 | Sangamo Biosciences, Inc. | Zinc finger polypeptides and their use |
| SI1546322T1 (sl) * | 2002-07-24 | 2011-05-31 | Manoa Biosciences Inc | Vektorji na osnovi transpozona in metode integracije nukleinskih kislin |
| WO2004069994A2 (en) * | 2003-02-10 | 2004-08-19 | Max-Delbrück-Centrum Für Molekulare Medizin (Mdc) | Transposon-based targeting system |
| ATE497540T1 (de) * | 2003-02-10 | 2011-02-15 | Max Delbrueck Centrum | Transposon-system zur gezielten integration |
| ATE536419T1 (de) | 2003-02-10 | 2011-12-15 | Max Delbrueck Centrum | Transposon basiertes targeting- system |
| KR20060054196A (ko) * | 2003-06-10 | 2006-05-22 | 주식회사 툴젠 | 전달가능한 dna-결합 단백질 |
| US20090208478A1 (en) * | 2003-10-24 | 2009-08-20 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8133733B2 (en) * | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| EP2418281B1 (en) * | 2003-10-24 | 2016-06-01 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8507277B2 (en) * | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| GB0328448D0 (en) * | 2003-12-09 | 2004-01-14 | Univ Leeds | Agents for the regulation of transcription via zinc finger proteins |
| EP1707575A1 (de) * | 2005-04-01 | 2006-10-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Ligation synthetischer Zinkfinger-Peptide zu seriellen Bindeproteinen für die spezifische Adressierung doppelstrangiger DNA-Bereiche (Zinkfinger-Sonden) |
| WO2007024029A1 (en) * | 2005-08-26 | 2007-03-01 | Kyoto University | Antiviral agent and viral replication inhibitor |
| WO2007102618A1 (en) * | 2006-03-08 | 2007-09-13 | Kyoto University | Nucleic acid cleaving agent |
| GB0607063D0 (en) | 2006-04-07 | 2006-05-17 | Cellcentric Ltd | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
| US7977535B2 (en) | 2006-07-12 | 2011-07-12 | Board Of Trustees Of Michigan State University | DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants |
| PT2205749T (pt) * | 2007-09-27 | 2016-07-20 | Dow Agrosciences Llc | Proteínas de dedo de zinco modificadas por engenharia que visam genes de 5-enolpiruvil-chiquimato-3-fosfato-sintase |
| US20100316702A1 (en) * | 2008-01-08 | 2010-12-16 | The Regents Of The University Of California | Compositions and methods for regulating erythropoeitin expression and ameliorating anemia and stimulating erythropoiesis |
| US10316288B2 (en) * | 2008-04-30 | 2019-06-11 | Sanbio, Inc. | Neural regenerating cells with alterations in DNA methylation |
| EP2130836B1 (en) * | 2008-06-03 | 2013-02-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Means and methods for producing zinc fingers and concatemers thereof |
| EP2461819A4 (en) * | 2009-07-28 | 2013-07-31 | Sangamo Biosciences Inc | METHODS AND COMPOSITIONS FOR TREATING TRI-NUCLEOTIDE REPEAT DISORDERS |
| CN103003425A (zh) * | 2010-06-07 | 2013-03-27 | 世良贵史 | 双生病毒复制抑制剂 |
| US9746475B2 (en) | 2011-03-14 | 2017-08-29 | University Of Southern California | Antibody and antibody mimetic for visualization and ablation of endogenous proteins |
| IL293650B2 (en) | 2011-09-21 | 2024-10-01 | Sangamo Therapeutics Inc | Methods and compositions for regulation of transgene expression |
| JP2015013810A (ja) * | 2011-10-27 | 2015-01-22 | 貴史 世良 | ジェミニウイルス複製阻害剤 |
| US10689643B2 (en) | 2011-11-22 | 2020-06-23 | Active Motif, Inc. | Targeted transposition for use in epigenetic studies |
| MX374399B (es) | 2012-02-29 | 2025-03-06 | Sangamo Biosciences Inc | Composiciones y sus usos para tratar y prevenir la enfermedad de huntington. |
| US9890364B2 (en) * | 2012-05-29 | 2018-02-13 | The General Hospital Corporation | TAL-Tet1 fusion proteins and methods of use thereof |
| EP4074330A1 (en) * | 2013-09-05 | 2022-10-19 | Massachusetts Institute of Technology | Tuning microbial populations with programmable nucleases |
| WO2015070212A1 (en) | 2013-11-11 | 2015-05-14 | Sangamo Biosciences, Inc. | Methods and compositions for treating huntington's disease |
| KR102816410B1 (ko) * | 2019-02-13 | 2025-06-04 | 프로바이오겐 아게 | 향상된 삽입 부위 선택 특성을 지닌 트랜스포사제(transposase) |
| WO2021101980A1 (en) * | 2019-11-19 | 2021-05-27 | The Regents Of The University Of California | Compositions and methods of using engineered fusion proteins that bind g4c2 human repeats |
| CN113368253B (zh) * | 2020-03-10 | 2022-06-10 | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 基于沸石咪唑框架结构的药物载体及其制备方法与应用 |
| WO2024026232A1 (en) * | 2022-07-27 | 2024-02-01 | Pioneer Hi-Bred International, Inc | Guide rna trapped genome editing |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763209A (en) * | 1988-09-26 | 1998-06-09 | Arch Development Corporation | Methods and materials relating to the functional domains of DNA binding proteins |
| EP0475779A1 (en) * | 1990-09-14 | 1992-03-18 | Vittal Mallya Scientific Research Foundation | Process for the separation of proteins, polypeptides or metals using immobilized, optionally modified, phosvitin |
| JPH06505152A (ja) * | 1990-12-21 | 1994-06-16 | ザ ロックフェラー ユニヴァーシティ | 肝集積性転写因子 |
| US5792640A (en) * | 1992-04-03 | 1998-08-11 | The Johns Hopkins University | General method to clone hybrid restriction endonucleases using lig gene |
| US5436150A (en) * | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5916794A (en) * | 1992-04-03 | 1999-06-29 | Johns Hopkins University | Methods for inactivating target DNA and for detecting conformational change in a nucleic acid |
| US6107059A (en) * | 1992-04-29 | 2000-08-22 | Affymax Technologies N.V. | Peptide library and screening method |
| AU684524B2 (en) * | 1993-06-14 | 1997-12-18 | Tet Systems Holding Gmbh & Co. Kg | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| CA2181548C (en) * | 1994-01-18 | 2009-11-03 | Carlos F. Barbas, Iii | Zinc finger protein derivatives and methods therefor |
| US6140466A (en) * | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US5837692A (en) * | 1994-04-07 | 1998-11-17 | Mercola; Dan | Inhibition of the mitogenic activity of PDGF by mammalian EGr |
| US5972643A (en) * | 1994-06-17 | 1999-10-26 | Fred Hutchinson Cancer Research Center | Isolated polynucleotide molecules encoding CTCF, a CCCTC-binding factor |
| US5831008A (en) * | 1994-08-18 | 1998-11-03 | La Jolla Cancer Research Foundation | Retinoblastoma protein-interacting zinc finger proteins |
| GB9824544D0 (en) * | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| AU698152B2 (en) * | 1994-08-20 | 1998-10-22 | Gendaq Limited | Improvements in or relating to binding proteins for recognition of DNA |
| US6008190A (en) * | 1994-12-15 | 1999-12-28 | California Institute Of Technology | Cobalt Schiff base compounds |
| US5789538A (en) * | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US6218522B1 (en) * | 1996-03-19 | 2001-04-17 | Shionogi & Co., Ltd. | DNA molecule relating to suppression of gene expression and novel protein |
| US6090783A (en) * | 1995-03-24 | 2000-07-18 | Shionogi & Co., Ltd. | DNA molecule relating to suppression of gene expression and novel protein |
| US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
| CN1192106C (zh) * | 1995-06-23 | 2005-03-09 | 丹尼斯科成分公司(丹尼斯科公司) | 分离突变体及克隆互补基因的新方法 |
| US6017734A (en) * | 1995-07-07 | 2000-01-25 | The Texas A & M University System | Unique nucleotide and amino acid sequence and uses thereof |
| US5770720A (en) * | 1995-08-30 | 1998-06-23 | Barnes-Jewish Hospital | Ubiquitin conjugating enzymes having transcriptional repressor activity |
| US5981217A (en) * | 1995-12-11 | 1999-11-09 | Mayo Foundation For Medical Education And Research | DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts |
| US5905146A (en) * | 1996-03-15 | 1999-05-18 | University Of Arkansas | DNA binding protein S1-3 |
| US5928955A (en) * | 1996-03-22 | 1999-07-27 | California Institute Of Technology | Peptidyl fluorescent chemosensor for divalent zinc |
| US5928941A (en) * | 1996-10-07 | 1999-07-27 | President And Fellows Of Harvard College | Repressor kruppel-like factor |
| US5869250A (en) * | 1996-12-02 | 1999-02-09 | The University Of North Carolina At Chapel Hill | Method for the identification of peptides that recognize specific DNA sequences |
| US6235538B1 (en) * | 1997-03-05 | 2001-05-22 | The Board Of Regents Of The University Of Oklahoma | Test for detecting substances which alter the conformational structure of zinc fingers |
| GB9710809D0 (en) * | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) * | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| WO1999010510A2 (en) * | 1997-08-26 | 1999-03-04 | Ariad Gene Therapeutics, Inc. | Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain |
| US6153383A (en) * | 1997-12-09 | 2000-11-28 | Verdine; Gregory L. | Synthetic transcriptional modulators and uses thereof |
| US6410248B1 (en) * | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| IL137952A0 (en) * | 1998-02-20 | 2001-10-31 | Genome Dynamics Inc | Method for designing dna-binding proteins of the zinc-finger class |
| ATE336578T1 (de) * | 1998-03-17 | 2006-09-15 | Gendaq Ltd | Nukleinsäurebindungsproteine |
| US6100035A (en) * | 1998-07-14 | 2000-08-08 | Cistem Molecular Corporation | Method of identifying cis acting nucleic acid elements |
| US6140081A (en) * | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6453242B1 (en) * | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) * | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| AU2001252428A1 (en) * | 2000-05-08 | 2001-11-20 | Gendaq Limited | Nucleic acid binding polypeptides |
-
2001
- 2001-07-19 AU AU2001278496A patent/AU2001278496A1/en not_active Abandoned
- 2001-07-19 EP EP01956547A patent/EP1303608A2/en not_active Withdrawn
- 2001-07-19 CA CA002416664A patent/CA2416664A1/en not_active Abandoned
- 2001-07-19 JP JP2002514190A patent/JP2004519211A/ja active Pending
- 2001-07-19 US US10/333,487 patent/US20040091878A1/en not_active Abandoned
- 2001-07-19 IL IL15405901A patent/IL154059A0/xx unknown
- 2001-07-19 WO PCT/EP2001/008367 patent/WO2002008286A2/en not_active Ceased
- 2001-07-20 AR ARP010103462A patent/AR034129A1/es not_active Application Discontinuation
- 2001-07-23 US US09/911,261 patent/US20030134350A1/en not_active Abandoned
-
2003
- 2003-01-02 ZA ZA200300651A patent/ZA200300651B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002008286A2 (en) | 2002-01-31 |
| US20040091878A1 (en) | 2004-05-13 |
| ZA200300651B (en) | 2003-11-11 |
| JP2004519211A (ja) | 2004-07-02 |
| CA2416664A1 (en) | 2002-01-31 |
| EP1303608A2 (en) | 2003-04-23 |
| AU2001278496A1 (en) | 2002-02-05 |
| US20030134350A1 (en) | 2003-07-17 |
| AR034129A1 (es) | 2004-02-04 |
| WO2002008286A3 (en) | 2002-07-11 |
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