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IL137952A0 - Method for designing dna-binding proteins of the zinc-finger class - Google Patents

Method for designing dna-binding proteins of the zinc-finger class

Info

Publication number
IL137952A0
IL137952A0 IL13795299A IL13795299A IL137952A0 IL 137952 A0 IL137952 A0 IL 137952A0 IL 13795299 A IL13795299 A IL 13795299A IL 13795299 A IL13795299 A IL 13795299A IL 137952 A0 IL137952 A0 IL 137952A0
Authority
IL
Israel
Prior art keywords
zinc
binding proteins
designing dna
finger class
designing
Prior art date
Application number
IL13795299A
Original Assignee
Genome Dynamics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Dynamics Inc filed Critical Genome Dynamics Inc
Publication of IL137952A0 publication Critical patent/IL137952A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13795299A 1998-02-20 1999-02-19 Method for designing dna-binding proteins of the zinc-finger class IL137952A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7546698P 1998-02-20 1998-02-20
PCT/US1999/003692 WO1999042474A2 (en) 1998-02-20 1999-02-19 Method for designing dna-binding proteins of the zinc-finger class

Publications (1)

Publication Number Publication Date
IL137952A0 true IL137952A0 (en) 2001-10-31

Family

ID=22125943

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13795299A IL137952A0 (en) 1998-02-20 1999-02-19 Method for designing dna-binding proteins of the zinc-finger class

Country Status (8)

Country Link
US (1) US6205404B1 (en)
EP (1) EP1062227A2 (en)
JP (1) JP2003502007A (en)
KR (1) KR20010041088A (en)
AU (1) AU758728B2 (en)
CA (1) CA2321088A1 (en)
IL (1) IL137952A0 (en)
WO (1) WO1999042474A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0781331B1 (en) 1994-08-20 2008-09-03 Gendaq Limited Improvements in or relating to binding proteins for recognition of dna
GB9824544D0 (en) 1998-11-09 1999-01-06 Medical Res Council Screening system
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
US6410248B1 (en) 1998-01-30 2002-06-25 Massachusetts Institute Of Technology General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
ES2341926T3 (en) 1998-03-02 2010-06-29 Massachusetts Institute Of Technology POLYPROTEINS WITH ZINC FINGERS THAT HAVE IMPROVED LINKERS.
WO1999047656A2 (en) 1998-03-17 1999-09-23 Gendaq Limited Nucleic acid binding proteins
US6453242B1 (en) 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
GB2360285B (en) * 1999-01-12 2002-02-27 Sangamo Biosciences Inc Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
US6599692B1 (en) 1999-09-14 2003-07-29 Sangamo Bioscience, Inc. Functional genomics using zinc finger proteins
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7013219B2 (en) 1999-01-12 2006-03-14 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7070934B2 (en) 1999-01-12 2006-07-04 Sangamo Biosciences, Inc. Ligand-controlled regulation of endogenous gene expression
US7030215B2 (en) 1999-03-24 2006-04-18 Sangamo Biosciences, Inc. Position dependent recognition of GNN nucleotide triplets by zinc fingers
US20030104526A1 (en) 1999-03-24 2003-06-05 Qiang Liu Position dependent recognition of GNN nucleotide triplets by zinc fingers
US6794136B1 (en) 2000-11-20 2004-09-21 Sangamo Biosciences, Inc. Iterative optimization in the design of binding proteins
CA2394850C (en) 1999-12-06 2012-02-07 Sangamo Biosciences, Inc. Methods of using randomized libraries of zinc finger proteins for the identification of gene function
DE60126913T2 (en) * 2000-01-24 2007-06-28 Gendaq Ltd. NUCLEIC ACID BINDING POLYPEPTIDE IS IDENTIFIED BY FLEXIBLE LINKER-LINKED NUCLEIC ACID ACID
IL154059A0 (en) * 2000-07-21 2003-07-31 Syngenta Participations Ag Zinc finger domain recognition code and uses thereof
US20020061510A1 (en) * 2000-10-16 2002-05-23 Jonathan Miller Method and system for designing proteins and protein backbone configurations
US7067317B2 (en) 2000-12-07 2006-06-27 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
CA2431308C (en) 2000-12-07 2010-04-13 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US7947469B2 (en) 2001-01-22 2011-05-24 Gendaq, Ltd. Modulation of HIV infection
AU2002241946B2 (en) 2001-01-22 2007-04-26 Sangamo Therapeutics, Inc. Modified zinc finger binding proteins
WO2003016496A2 (en) * 2001-08-20 2003-02-27 The Scripps Research Institute Zinc finger binding domains for cnn
US7262054B2 (en) 2002-01-22 2007-08-28 Sangamo Biosciences, Inc. Zinc finger proteins for DNA binding and gene regulation in plants
EP1535235A1 (en) * 2002-05-28 2005-06-01 The Trustees of The University of Pennsylvania Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers
US7361635B2 (en) 2002-08-29 2008-04-22 Sangamo Biosciences, Inc. Simultaneous modulation of multiple genes
JP2020524490A (en) 2017-06-06 2020-08-20 ザイマージェン インコーポレイテッド HTP genome manipulation platform to improve Escherichia coli

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096815A (en) * 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
US5331573A (en) * 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
WO1996032475A2 (en) * 1995-04-12 1996-10-17 University Of Washington Methods for preparing dna-binding proteins

Also Published As

Publication number Publication date
WO1999042474A2 (en) 1999-08-26
CA2321088A1 (en) 1999-08-26
KR20010041088A (en) 2001-05-15
US6205404B1 (en) 2001-03-20
AU2871199A (en) 1999-09-06
WO1999042474A3 (en) 1999-10-21
EP1062227A2 (en) 2000-12-27
JP2003502007A (en) 2003-01-21
AU758728B2 (en) 2003-03-27

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